메뉴 건너뛰기




Volumn 64, Issue 1, 2003, Pages 42-50

Transgenic mouse models of human CYP3A4 gene regulation

Author keywords

[No Author keywords available]

Indexed keywords

16ALPHA CARBONITRILE; BETA GALACTOSIDASE; CONSTITUTIVE ANDROSTANE RECEPTOR; CYANIDE; CYTOCHROME P450 3A4; DEXAMETHASONE; DRUG METABOLIZING ENZYME; PHENOBARBITAL; PREGNANE X RECEPTOR; PREGNENOLONE; STEROID RECEPTOR; UNCLASSIFIED DRUG; XENOBIOTIC AGENT;

EID: 0038575830     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.64.1.42     Document Type: Article
Times cited : (63)

References (40)
  • 1
    • 0024412071 scopus 로고
    • Cytochrome P-450 hPCN3, a novel cytochrome P-450 IIIA gene product that is differentially expressed in adult human liver, cDNA and deduced amino acid sequence and distinct specificities of cDNA-expressed hPCN1 and hPCN3 for the metabolism of steroid hormones and cyclosporine
    • Aoyama T, Yamano S, Waxman DJ, Lapenson DP, Meyer UA, Fischer V, Tyndale R, Inaba T, Kalow W, and Gelboin HV (1989) Cytochrome P-450 hPCN3, a novel cytochrome P-450 IIIA gene product that is differentially expressed in adult human liver, cDNA and deduced amino acid sequence and distinct specificities of cDNA-expressed hPCN1 and hPCN3 for the metabolism of steroid hormones and cyclosporine. J Biol Chem 264:10388-10395.
    • (1989) J Biol Chem , vol.264 , pp. 10388-10395
    • Aoyama, T.1    Yamano, S.2    Waxman, D.J.3    Lapenson, D.P.4    Meyer, U.A.5    Fischer, V.6    Tyndale, R.7    Inaba, T.8    Kalow, W.9    Gelboin, H.V.10
  • 2
    • 0033583336 scopus 로고    scopus 로고
    • 6α-Hydroxylation of taurochenodeoxycholic acid and lithocholic acid by CYP3A4 in human liver microsomes
    • Araya Z and Wikvall K (1999) 6α-Hydroxylation of taurochenodeoxycholic acid and lithocholic acid by CYP3A4 in human liver microsomes. Biochim Biophys Acta 1438:47-54.
    • (1999) Biochim Biophys Acta , vol.1438 , pp. 47-54
    • Araya, Z.1    Wikvall, K.2
  • 3
    • 0029992789 scopus 로고    scopus 로고
    • Trans-species gene transfer for analysis of glucocorticoid-inducible transcriptional activation of transiently expressed human CYP3A4 and rabbit CYP3A6 in primary cultures of adult rat and rabbit hepatocytes
    • Barwick JL, Quattrochi LC, Mills AS, Potenza C, Tukey RH, and Guzelian PS (1996) Trans-species gene transfer for analysis of glucocorticoid-inducible transcriptional activation of transiently expressed human CYP3A4 and rabbit CYP3A6 in primary cultures of adult rat and rabbit hepatocytes. Mol Pharmacol 50:10-16.
    • (1996) Mol Pharmacol , vol.50 , pp. 10-16
    • Barwick, J.L.1    Quattrochi, L.C.2    Mills, A.S.3    Potenza, C.4    Tukey, R.H.5    Guzelian, P.S.6
  • 6
    • 0025646757 scopus 로고
    • Catalytic activities of human liver cytochrome P-450 IIIA4 expressed in Saccharomyces cerevisiae
    • Brian WR, Sari MA, Iwasaki M, Shimada T, Kaminsky LS, and Guengerich FP (1990) Catalytic activities of human liver cytochrome P-450 IIIA4 expressed in Saccharomyces cerevisiae. Biochemistry 29:11280-11292.
    • (1990) Biochemistry , vol.29 , pp. 11280-11292
    • Brian, W.R.1    Sari, M.A.2    Iwasaki, M.3    Shimada, T.4    Kaminsky, L.S.5    Guengerich, F.P.6
  • 8
    • 0023688694 scopus 로고
    • Structure and expression of the human metallothionein-IG gene. Differential promoter activity of two linked metanothionein-I genes in response to heavy metals
    • Foster R, Jahroudi N, Varshney U, and Gedamu L (1988) Structure and expression of the human metallothionein-IG gene. Differential promoter activity of two linked metanothionein-I genes in response to heavy metals. J Biol Chem 263:11528-11535.
    • (1988) J Biol Chem , vol.263 , pp. 11528-11535
    • Foster, R.1    Jahroudi, N.2    Varshney, U.3    Gedamu, L.4
  • 10
    • 0036070955 scopus 로고    scopus 로고
    • Transcriptional regulation of the human CYP3A4 gene by the constitutive androstane receptor
    • Goodwin B, Hodgson E, D'Costa DJ, Robertson GR, and Liddle C (2002) Transcriptional regulation of the human CYP3A4 gene by the constitutive androstane receptor. Mol Pharmacol 62:359-365.
    • (2002) Mol Pharmacol , vol.62 , pp. 359-365
    • Goodwin, B.1    Hodgson, E.2    D'Costa, D.J.3    Robertson, G.R.4    Liddle, C.5
  • 11
    • 0032702726 scopus 로고    scopus 로고
    • The orphan human pregnane X receptor mediates the transcriptional activation of CYP3A4 by rifampicin through a distal enhancer module
    • Goodwin BJ, Hodgson E, and Liddle C (1999) The orphan human pregnane X receptor mediates the transcriptional activation of CYP3A4 by rifampicin through a distal enhancer module. Mol Pharmacol 56:1329-1339.
    • (1999) Mol Pharmacol , vol.56 , pp. 1329-1339
    • Goodwin, B.J.1    Hodgson, E.2    Liddle, C.3
  • 12
    • 0023141516 scopus 로고
    • In situ detection of β-galactosidase in lenses of transgenic mice with a γ-crystallin/lacZ gene
    • Goring DR, Rossant J, Clapoff S, Breitman ML, and Tsui LC (1987) In situ detection of β-galactosidase in lenses of transgenic mice with a γ-crystallin/lacZ gene. Science (Wash DC) 235:456-458.
    • (1987) Science (Wash DC) , vol.235 , pp. 456-458
    • Goring, D.R.1    Rossant, J.2    Clapoff, S.3    Breitman, M.L.4    Tsui, L.C.5
  • 13
    • 0028556593 scopus 로고
    • A novel form of mouse cytochrome P450 3A (Cyp3A-16). Its cDNA cloning and expression in fetal liver
    • Itoh S, Satoh M, Abe Y, Hashimoto H, Yanagimoto T, and Kamataki T (1994) A novel form of mouse cytochrome P450 3A (Cyp3A-16). Its cDNA cloning and expression in fetal liver. Eur J Biochem 226:877-882.
    • (1994) Eur J Biochem , vol.226 , pp. 877-882
    • Itoh, S.1    Satoh, M.2    Abe, Y.3    Hashimoto, H.4    Yanagimoto, T.5    Kamataki, T.6
  • 16
    • 0024356688 scopus 로고
    • Isolation of a new human fetal liver cytochrome P450 cDNA clone: Evidence for expression of a limited number of forms of cytochrome P450 in human fetal livers
    • Komori M, Nishio K, Fujitani T, Ohi H, Kitada M, Mima S, Itahashi K, and Kamataki T (1989) Isolation of a new human fetal liver cytochrome P450 cDNA clone: evidence for expression of a limited number of forms of cytochrome P450 in human fetal livers. Arch Biochem Biophys 272:219-225.
    • (1989) Arch Biochem Biophys , vol.272 , pp. 219-225
    • Komori, M.1    Nishio, K.2    Fujitani, T.3    Ohi, H.4    Kitada, M.5    Mima, S.6    Itahashi, K.7    Kamataki, T.8
  • 17
    • 0030750270 scopus 로고    scopus 로고
    • Expression of CYP3A in the human liver - Evidence that the shift between CYP3A7 and CYP3A4 occurs immediately after birth
    • Lacroix D, Sonnier M, Moncion A, Cheron G, and Cresteil T (1997) Expression of CYP3A in the human liver - evidence that the shift between CYP3A7 and CYP3A4 occurs immediately after birth. Eur J Biochem 247:625-634.
    • (1997) Eur J Biochem , vol.247 , pp. 625-634
    • Lacroix, D.1    Sonnier, M.2    Moncion, A.3    Cheron, G.4    Cresteil, T.5
  • 19
    • 0032169485 scopus 로고    scopus 로고
    • The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions
    • Lehmann JM, McKee DD, Watson MA, Willson TM, Moore JT, and Kliewer SA (1998) The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions. J Clin Investig 102:1016-1023.
    • (1998) J Clin Investig , vol.102 , pp. 1016-1023
    • Lehmann, J.M.1    McKee, D.D.2    Watson, M.A.3    Willson, T.M.4    Moore, J.T.5    Kliewer, S.A.6
  • 20
    • 0031785886 scopus 로고    scopus 로고
    • Separate and interactive regulation of cytochrome P450 3A4 by triiodothyronine, dexamethasone and growth hormone in cultured hepatocytes
    • Liddle C, Goodwin BJ, George J, Tapner M, and Farrell GC (1998) Separate and interactive regulation of cytochrome P450 3A4 by triiodothyronine, dexamethasone and growth hormone in cultured hepatocytes. J Clin Endocrinol Metab 83:2411-2416.
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 2411-2416
    • Liddle, C.1    Goodwin, B.J.2    George, J.3    Tapner, M.4    Farrell, G.C.5
  • 26
    • 0023061373 scopus 로고
    • P450 genes: Structure, evolution and regulation
    • Nebert DW and Gonzalez FJ (1987) P450 genes: structure, evolution and regulation. Annu Rev Biochem 56:945-993.
    • (1987) Annu Rev Biochem , vol.56 , pp. 945-993
    • Nebert, D.W.1    Gonzalez, F.J.2
  • 27
    • 0036045940 scopus 로고    scopus 로고
    • Differential metabolism of alprazolam by liver and brain cytochrome (P4503A) to pharmacologically active metabolite
    • Pai HV, Upadhya SC, Chinta SJ, Hegde SN, and Ravindranath V (2002) Differential metabolism of alprazolam by liver and brain cytochrome (P4503A) to pharmacologically active metabolite. Pharmacogenomics J 2:243-258.
    • (2002) Pharmacogenomics J , vol.2 , pp. 243-258
    • Pai, H.V.1    Upadhya, S.C.2    Chinta, S.J.3    Hegde, S.N.4    Ravindranath, V.5
  • 28
    • 0033548431 scopus 로고    scopus 로고
    • Distinctive roles of STAT5a and STAT5b in sexual dimorphism of hepatic P450 gene expression
    • Park S-H, Liu X, Hennighausen L, Davey HW, and Waxman DJ (1999) Distinctive roles of STAT5a and STAT5b in sexual dimorphism of hepatic P450 gene expression. J Biol Chem 274:7421-7430.
    • (1999) J Biol Chem , vol.274 , pp. 7421-7430
    • Park, S.-H.1    Liu, X.2    Hennighausen, L.3    Davey, H.W.4    Waxman, D.J.5
  • 30
    • 0027180023 scopus 로고
    • Identification of the fetal liver cytochrome 3A7 in human endometrium and placenta
    • Schuetz JD, Kauma S, and Guzelian PS (1993) Identification of the fetal liver cytochrome 3A7 in human endometrium and placenta. J Clin Investig 92:1018-1024.
    • (1993) J Clin Investig , vol.92 , pp. 1018-1024
    • Schuetz, J.D.1    Kauma, S.2    Guzelian, P.S.3
  • 31
    • 0028175687 scopus 로고
    • Selective expression of cytochrome P450 CYP3A mRNAs in embryonic and adult human liver
    • Schuetz JD, Beach DL, and Guzelian PS (1994) Selective expression of cytochrome P450 CYP3A mRNAs in embryonic and adult human liver. Pharmacogenetics 4:11-20.
    • (1994) Pharmacogenetics , vol.4 , pp. 11-20
    • Schuetz, J.D.1    Beach, D.L.2    Guzelian, P.S.3
  • 32
    • 0028237729 scopus 로고
    • Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: Studies with liver microsomes of 30 Japanese and 30 Caucasians
    • Shimada T, Yamazaki H, Mimura M, Inui Y, and Guengerich FP (1994) Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians. J Pharmacol Exp Ther 270:414-423.
    • (1994) J Pharmacol Exp Ther , vol.270 , pp. 414-423
    • Shimada, T.1    Yamazaki, H.2    Mimura, M.3    Inui, Y.4    Guengerich, F.P.5
  • 34
    • 0036509526 scopus 로고    scopus 로고
    • Toxicological consequences of differential regulation of cytochrome P450 isoforms in rat brain regions by phenobarbital
    • Upadhya SC, Chinta SJ, Pai HV, Boyd MR, and Ravindranath V (2002) Toxicological consequences of differential regulation of cytochrome P450 isoforms in rat brain regions by phenobarbital. Arch Biochem Biophys 399:56-65.
    • (2002) Arch Biochem Biophys , vol.399 , pp. 56-65
    • Upadhya, S.C.1    Chinta, S.J.2    Pai, H.V.3    Boyd, M.R.4    Ravindranath, V.5
  • 35
    • 0024556650 scopus 로고
    • Erythromycin breath test as an assay of glucocorticoid-inducible liver cytochromes P-450. Studies in rats and patients
    • Watkins PB, Murray SA, Winkelman LG, Heuman DM, Wrighton SA, and Guzelian PS (1989) Erythromycin breath test as an assay of glucocorticoid-inducible liver cytochromes P-450. Studies in rats and patients. J Clin Investig 83:688-697.
    • (1989) J Clin Investig , vol.83 , pp. 688-697
    • Watkins, P.B.1    Murray, S.A.2    Winkelman, L.G.3    Heuman, D.M.4    Wrighton, S.A.5    Guzelian, P.S.6
  • 39
    • 0036534671 scopus 로고    scopus 로고
    • Estrogen-dependent regulation of the expression of hepatic Cyp2b and 3a isoforms: Assessment using aromatase-deficient mice
    • Yamada H, Gohyama N, Honda S, Hara T, Harada N, and Oguri K (2002) Estrogen-dependent regulation of the expression of hepatic Cyp2b and 3a isoforms: assessment using aromatase-deficient mice. Toxicol Appl Pharmacol 180:1-10.
    • (2002) Toxicol Appl Pharmacol , vol.180 , pp. 1-10
    • Yamada, H.1    Gohyama, N.2    Honda, S.3    Hara, T.4    Harada, N.5    Oguri, K.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.