In vivo activation of the human CYP3A4 promoter in mouse liver and regulation by pregnane X receptors

Biochemical Pharmacology

Volumn 65, Issue 11, 2003, Pages 1889-1896

  Zhang, Weisheng ^a   Purchio, Anthony ^a   Chen, Kevin ^a   Burns, Stacy M ^b   Contag, Christopher H ^b   Contag, Pamela R ^a  

^a Xenogen Corporation   (United States)

^b STANFORD UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Cytochrome P450; Drug metabolism; Gene expression; Imaging; In vivo; Luciferase; Pregnane X receptor

Indexed keywords

CYTOCHROME P450 3A4; DEXAMETHASONE; DIMER; PREGNANE X RECEPTOR; RETINOID X RECEPTOR; RIFAMPICIN; XENOBIOTIC AGENT;

ANIMAL TISSUE; ARTICLE; BIOLUMINESCENCE; CONTROLLED STUDY; DIMERIZATION; DRUG ACTIVITY; ENZYME ACTIVATION; FEMALE; GENE EXPRESSION; HUMAN; IMAGING; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; REGULATORY MECHANISM;

EID: 0038392537     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(03)00188-6     Document Type: Article

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