A nuclear export signal in the N-terminal regulatory domain of IκBα controls cytoplasmic localization of inactive NF-κB/IκBα complexes

Proceedings of the National Academy of Sciences of the United States of America

Volumn 97, Issue 3, 2000, Pages 1014-1019

  Huang, Tony T ^a   Kudo, Nobuaki ^b   Yoshida, Minoru ^b   Miyamoto, Shigeki ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; IMMUNOGLOBULIN KAPPA CHAIN; LEPTOMYCIN B; SIGNAL PEPTIDE;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CELL MEMBRANE PERMEABILITY; CELL NUCLEUS; CELL STRAIN COS1; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOPLASM; EMBRYO; HELA CELL; HUMAN; HUMAN CELL; INTRACELLULAR TRANSPORT; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; SIGNAL TRANSDUCTION; SITE DIRECTED MUTAGENESIS;

AMINO ACID MOTIFS; ANIMALS; BIOLOGICAL TRANSPORT; CARRIER PROTEINS; CELL NUCLEUS; CERCOPITHECUS AETHIOPS; COS CELLS; CYTOPLASM; DNA; DNA-BINDING PROTEINS; FATTY ACIDS, UNSATURATED; HELA CELLS; HUMANS; I-KAPPA B PROTEINS; KARYOPHERINS; MACROMOLECULAR SUBSTANCES; MODELS, BIOLOGICAL; MUTAGENESIS, SITE-DIRECTED; NF-KAPPA B; PROTEIN SORTING SIGNALS; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECOMBINANT FUSION PROTEINS; SIGNAL TRANSDUCTION; TRANSCRIPTION, GENETIC; TRANSFECTION;

ANIMALIA;

EID: 0033953587     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.97.3.1014     Document Type: Article

References (34)

1. Baeuerle, P. A. & Baltimore, D. (1996) Cell 87, 13-20.
2. Verma, I. M., Stevenson, J. K., Schwarz, E. M., Van Antwerp, D. & Miyamoto, S. (1995) Genes Dev. 9, 2723-2735.
3. Baeuerle, P. A. & Baltimore, D. (1988) Cell 53, 211-217.
4. Arenzana-Seisdedos, F., Turpin, T., Rodriguez, M., Thomas, D., Hay, R. T., Virelizier, J.-L. & Dargemont, C. (1997) J. Cell Sci. 110, 369-378.
5. Cheng, Q., Cant, C. A., Moll, T., Hofer-Warbinek, R., Wagner, E., Birnstiel, M. L., Bach, F. H. & de Martin, R. (1994) J. Biol. Chem. 269, 13551-13557.
6. Chiao, P. J., Miyamoto, S. & Verma, I. M. (1994) Proc. Natl. Acad. Sci. USA 91, 28-32.
7. Arenzana-Seisdedos, F., Thompson, J., Rodriguez, M. S., Bachelerie, F., Thomas, D. & Hay, R. T. (1995) Mol. Cell. Biol. 15, 2689-2696.
8. Mattaj, I. W. & Englmeier, L. (1998) Annu. Rev. Biochem. 67, 265-306.
9. Fritz, C. C. & Green, M. R. (1996) Curr. Biol. 6, 848-854.
10. Toyoshima, F., Moriguchi, T., Wada, A., Fukuda, M. & Nishida, E. (1998) EMBO J. 17, 2728-2735.
11. Wen, W., Meinkoth, J. L., Tsien, R. Y. & Taylor, S. S. (1995) Cell 82, 463-473.
12. Nishi, K., Yoshida, M., Fujiwara, D., Nishikawa, M., Horinouchi, S. & Beppu, T. (1994) J. Biol. Chem. 269, 6320-6324.
13. Stade, K., Ford, C. S., Guthrie, C. & Weis, K. (1997) Cell 90, 1041-1050.
14. Kudo, N., Khochbin, S., Nishi, K., Kitano, K., Yanagida, M., Yoshida, M. & Horinouchi, S. (1997) J. Biol. Chem. 272, 29742-29751.
15. Fornerod, M., Ohno, M., Yoshida, M. & Mattaj, I. W. (1997) Cell 90, 1051-1060.
16. Fukuda, M., Asano, S., Nakamura, T., Adachi, M., Yoshida, M., Yanagida, M. & Nishida, E. (1997) Nature (London) 390, 308-311.
17. Kudo, N., Wolff, B., Sekimoto, T., Schreiner, E. P., Yoneda, Y., Yanagida, M., Horinouchi, S. & Yoshida, M. (1998) Exp. Cell Res. 242, 540-547.
18. Beg, A. A., Ruben, S. M., Scheinman, R. I., Haskill, S., Rosen, C. A. & Baldwin, A. S. J. (1992) Genes Dev. 6, 1899-1913.
19. Ganchi, P. A., Sun, S. C., Greene, W. C. & Ballard, D. W. (1992) Mol. Biol. Cell 3, 1339-1352.
20. Huxford, T., Huang, D.-B., Malek, S. & Ghosh, G. (1998) Cell 95, 759-770.
21. Jacobs, M. D. & Harrison, S. C. (1998) Cell 95, 749-758.
22. Sachdev, S. & Hannink, M. (1998) Mol. Cell. Biol. 18, 5445-5456.
23. Rodriguez, M. S., Thompson, J., Hay, R. T. & Dargemont, C. (1999) J. Biol. Chem. 274, 9108-9115.
24. Kudo, N., Matsumori, N., Taoka, H., Fujiwara, D., Schreiner, E. P., Wolff, B., Yosida, M. & Horinouchi, S. (1999) Proc. Natl. Acad. Sci. USA 96, 9112-9117.
25. Miyamoto, S., Seufzer, B. & Shumway, S. (1998) Mol. Cell. Biol. 18, 19-29.
26. Cao, Z. D., Xiong, J., Takeuchi, M., Kurama, T. & Goeddel, D. V. (1996) Nature (London) 383, 443-446.
27. Poste, G. (1972) Exp. Cell Res. 73, 273-286.
28. Nolan, G. P., Ghosh, S., Liou, H. C., Tempst, P. & Baltimore, D. (1991) Cell 64, 961-969.
29. Ghosh, S., Gifford, A. M., Riviere, L. R., Tempst, P., Nolan, G. P. & Baltimore, D. (1990) Cell 62, 1019-1029.
30. Ossareh-Nazari, B., Bachelerie, F. & Dargemont, C. (1997) Science 278, 141-144.
31. Lin, Y.-Z., Yao, S., Veach, R. A., Torgerson, T. R. & Hawiger, J. (1995) J. Biol. Chem. 270, 14255-14258.
32. Sachdev, S., Hoffmann, A. & Hannink, M. (1998) Mol. Cell. Biol. 18, 2524-2534.
33. Luque, I. & Gelinas, C. (1998) Mol. Cell. Biol. 18, 1213-1224.
34. Latimer, M., Ernst, M. K., Dunn, L. L., Drutskaya, M. & Rice, N. R. (1998) Mol. Cell. Biol. 18, 2640-2649.