메뉴 건너뛰기




Volumn 77, Issue 3, 2005, Pages 337-345

Recent developments in genomewide association scans: A workshop summary and review

Author keywords

[No Author keywords available]

Indexed keywords

ALLELE; CONFERENCE PAPER; DNA DETERMINATION; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENE MAPPING; GENETIC MARKER; GENETIC RISK; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GENOME ANALYSIS; GENOTYPE; HAPLOTYPE; HUMAN; PRIORITY JOURNAL; QUANTITATIVE TRAIT LOCUS; SINGLE NUCLEOTIDE POLYMORPHISM; STATISTICAL MODEL; TECHNIQUE; TECHNOLOGY;

EID: 23944469845     PISSN: 00029297     EISSN: None     Source Type: Journal    
DOI: 10.1086/432962     Document Type: Conference Paper
Times cited : (167)

References (82)
  • 2
    • 0036866635 scopus 로고    scopus 로고
    • Identification of the sources of error in allele frequency estimations from pooled DNA indicates an optimal experimental design
    • Barratt BJ, Payne F, Rance HE, Nutland S, Todd JA, Clayton DG (2002) Identification of the sources of error in allele frequency estimations from pooled DNA indicates an optimal experimental design. Ann Hum Genet 66:393-405
    • (2002) Ann Hum Genet , vol.66 , pp. 393-405
    • Barratt, B.J.1    Payne, F.2    Rance, H.E.3    Nutland, S.4    Todd, J.A.5    Clayton, D.G.6
  • 4
    • 0001677717 scopus 로고
    • Controlling the false discovery rate: A practical and powerful approach to multiple testing
    • Benjamini Y, Hochberg Y (1995) Controlling the false discovery rate: a practical and powerful approach to multiple testing. J R Stat Soc B 57:289-300
    • (1995) J R Stat Soc B , vol.57 , pp. 289-300
    • Benjamini, Y.1    Hochberg, Y.2
  • 5
    • 0028070381 scopus 로고
    • Limits of resolution of genetic linkage studies: Implications for the positional cloning of human disease genes
    • Boehnke M (1994) Limits of resolution of genetic linkage studies: implications for the positional cloning of human disease genes. Am J Hum Genet 55:379-390
    • (1994) Am J Hum Genet , vol.55 , pp. 379-390
    • Boehnke, M.1
  • 6
    • 0037373275 scopus 로고    scopus 로고
    • Discovering genotypes underlying human phenotypes: Past successes for mendelian disease, future approaches for complex disease
    • Botstein D, Risch N (2003) Discovering genotypes underlying human phenotypes: past successes for mendelian disease, future approaches for complex disease. Nat Genet 33:228-237
    • (2003) Nat Genet , vol.33 , pp. 228-237
    • Botstein, D.1    Risch, N.2
  • 7
    • 0035257236 scopus 로고    scopus 로고
    • Association study designs for complex diseases
    • Cardon LR, Bell JI (2001) Association study designs for complex diseases. Nat Rev Genet 2:91-99
    • (2001) Nat Rev Genet , vol.2 , pp. 91-99
    • Cardon, L.R.1    Bell, J.I.2
  • 8
    • 0037442092 scopus 로고    scopus 로고
    • Population stratification and spurious allelic association
    • Cardon LR, Palmer LJ (2003) Population stratification and spurious allelic association. Lancet 361:598-604
    • (2003) Lancet , vol.361 , pp. 598-604
    • Cardon, L.R.1    Palmer, L.J.2
  • 9
    • 0034139518 scopus 로고    scopus 로고
    • Mining for SNPs: Putting the common variants-common disease hypothesis to the test
    • Cargill M, Daley GQ (2000) Mining for SNPs: putting the common variants-common disease hypothesis to the test. Pharmacogenomics 1:27-37
    • (2000) Pharmacogenomics , vol.1 , pp. 27-37
    • Cargill, M.1    Daley, G.Q.2
  • 10
    • 2642583283 scopus 로고    scopus 로고
    • Mapping complex disease loci in whole-genome association studies
    • Carlson CS, Eberle MA, Kruglyak L, Nickerson DA (2004) Mapping complex disease loci in whole-genome association studies. Nature 429:446-452
    • (2004) Nature , vol.429 , pp. 446-452
    • Carlson, C.S.1    Eberle, M.A.2    Kruglyak, L.3    Nickerson, D.A.4
  • 11
    • 0344091561 scopus 로고    scopus 로고
    • Additional SNPs and linkage-disequilibrium analyses are necessary for whole-genome association studies in humans
    • Carlson CS, Eberle MA, Rieder MJ, Smith JD, Kruglyak L, Nickerson DA (2003) Additional SNPs and linkage-disequilibrium analyses are necessary for whole-genome association studies in humans. Nat Genet 33:518-521
    • (2003) Nat Genet , vol.33 , pp. 518-521
    • Carlson, C.S.1    Eberle, M.A.2    Rieder, M.J.3    Smith, J.D.4    Kruglyak, L.5    Nickerson, D.A.6
  • 12
    • 0035922669 scopus 로고    scopus 로고
    • Epidemiological methods for studying genes and environmental factors in complex diseases
    • Clayton DG, McKeigue PM (2001) Epidemiological methods for studying genes and environmental factors in complex diseases. Lancet 358:1357-1360
    • (2001) Lancet , vol.358 , pp. 1357-1360
    • Clayton, D.G.1    McKeigue, P.M.2
  • 13
    • 0030688004 scopus 로고    scopus 로고
    • Variations on a theme: Cataloging human DNA sequence variation
    • Collins FS, Guyer MS, Charkravarti A (1997) Variations on a theme: cataloging human DNA sequence variation. Science 278:1580-1581
    • (1997) Science , vol.278 , pp. 1580-1581
    • Collins, F.S.1    Guyer, M.S.2    Charkravarti, A.3
  • 14
    • 0035528921 scopus 로고    scopus 로고
    • Genomic control, a new approach to genetic-based association studies
    • Devlin B, Roeder K, Wasserman L (2001) Genomic control, a new approach to genetic-based association studies. Theor Pop Biol 60:155-160
    • (2001) Theor Pop Biol , vol.60 , pp. 155-160
    • Devlin, B.1    Roeder, K.2    Wasserman, L.3
  • 15
    • 0035992248 scopus 로고    scopus 로고
    • Empirical Bayes methods and false discovery rates for microarrays
    • Efron B, Tibshirani R (2002) Empirical Bayes methods and false discovery rates for microarrays. Genet Epidemiol 23: 70-86
    • (2002) Genet Epidemiol , vol.23 , pp. 70-86
    • Efron, B.1    Tibshirani, R.2
  • 16
    • 7444260846 scopus 로고    scopus 로고
    • The ENCODE (ENCyclopedia of DNA Elements) Project
    • ENCODE Project Consortium (2004) The ENCODE (ENCyclopedia Of DNA Elements) Project. Science 306:636-640
    • (2004) Science , vol.306 , pp. 636-640
  • 20
    • 0034917944 scopus 로고    scopus 로고
    • A transmission/disequilibrium test that allows for genotyping errors in the analysis of single-nucleotide polymorphism data
    • Gordon D, Heath SC, Liu X, Ott J (2001) A transmission/disequilibrium test that allows for genotyping errors in the analysis of single-nucleotide polymorphism data. Am J Hum Genet 69:371-380
    • (2001) Am J Hum Genet , vol.69 , pp. 371-380
    • Gordon, D.1    Heath, S.C.2    Liu, X.3    Ott, J.4
  • 21
    • 18544362940 scopus 로고    scopus 로고
    • Increasing power for tests of genetic association in the presence of phenotype and/or genotype error by use of double-sampling
    • Gordon D, Yang Y, Haynes C, Finch SJ, Mendell NR, Brown AM, Haroutunian V (2004) Increasing power for tests of genetic association in the presence of phenotype and/or genotype error by use of double-sampling. Stat Appl Genet Mol Biol 3:1-35
    • (2004) Stat Appl Genet Mol Biol , vol.3 , pp. 1-35
    • Gordon, D.1    Yang, Y.2    Haynes, C.3    Finch, S.J.4    Mendell, N.R.5    Brown, A.M.6    Haroutunian, V.7
  • 22
    • 19944401078 scopus 로고    scopus 로고
    • Incorporating individual error rate into association test of unmatched case-control design
    • Hao K, Wang X (2004) Incorporating individual error rate into association test of unmatched case-control design. Hum Hered 58:154-163
    • (2004) Hum Hered , vol.58 , pp. 154-163
    • Hao, K.1    Wang, X.2
  • 24
    • 13144306071 scopus 로고    scopus 로고
    • Genome-wide association studies for common disease and complex traits
    • Hirschhorn JN, Daly MJ (2005) Genome-wide association studies for common disease and complex traits. Nat Rev Genet 6:95-108
    • (2005) Nat Rev Genet , vol.6 , pp. 95-108
    • Hirschhorn, J.N.1    Daly, M.J.2
  • 29
    • 6344233909 scopus 로고    scopus 로고
    • Finding haplotype tagging SNPs by use of principal components analysis
    • Lin Z, Altman RB (2004) Finding haplotype tagging SNPs by use of principal components analysis. Am J Hum Genet 75: 850-861
    • (2004) Am J Hum Genet , vol.75 , pp. 850-861
    • Lin, Z.1    Altman, R.B.2
  • 30
    • 13144282294 scopus 로고    scopus 로고
    • Exhaustive allelic transmission disequilibrium tests as a new approach to genomewide association studies
    • Lin S, Chakravarti A, Cutler DJ (2004) Exhaustive allelic transmission disequilibrium tests as a new approach to genomewide association studies. Nat Genet 36:1181-1188
    • (2004) Nat Genet , vol.36 , pp. 1181-1188
    • Lin, S.1    Chakravarti, A.2    Cutler, D.J.3
  • 32
    • 0037312921 scopus 로고    scopus 로고
    • Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease
    • Lohmueller KE, Pearce CL, Pike MC, Lander ES, Hirschhorn JN (2003) Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease. Nat Genet 33:177-182
    • (2003) Nat Genet , vol.33 , pp. 177-182
    • Lohmueller, K.E.1    Pearce, C.L.2    Pike, M.C.3    Lander, E.S.4    Hirschhorn, J.N.5
  • 35
    • 16844366786 scopus 로고    scopus 로고
    • Genome-wide strategies for detecting multiple loci that influence complex diseases
    • Marchini J, Donnelly P, Cardon LR (2005) Genome-wide strategies for detecting multiple loci that influence complex diseases. Nat Genet 37:413-417
    • (2005) Nat Genet , vol.37 , pp. 413-417
    • Marchini, J.1    Donnelly, P.2    Cardon, L.R.3
  • 36
    • 0037371453 scopus 로고    scopus 로고
    • Undetected genotyping errors cause apparent overtransmission of common alleles in the transmission/disequilibrium test
    • Mitchell AA, Cutler DJ, Chakravarti A (2003) Undetected genotyping errors cause apparent overtransmission of common alleles in the transmission/ disequilibrium test. Am J Hum Genet 72:598-610
    • (2003) Am J Hum Genet , vol.72 , pp. 598-610
    • Mitchell, A.A.1    Cutler, D.J.2    Chakravarti, A.3
  • 39
    • 4143134235 scopus 로고    scopus 로고
    • The future of association studies: Gene-based analysis and replication
    • Neale BM, Sham PC (2004) The future of association studies: gene-based analysis and replication. Am J Hum Genet 75: 353-362
    • (2004) Am J Hum Genet , vol.75 , pp. 353-362
    • Neale, B.M.1    Sham, P.C.2
  • 41
    • 0043122919 scopus 로고    scopus 로고
    • SIFT: Predicting amino acid changes that affect protein function
    • Ng PC, Henikoff S (2003) SIFT: Predicting amino acid changes that affect protein function. Nucleic Acids Res 31:3812-3814
    • (2003) Nucleic Acids Res , vol.31 , pp. 3812-3814
    • Ng, P.C.1    Henikoff, S.2
  • 42
    • 0036468808 scopus 로고    scopus 로고
    • Linkage disequilibrium: What history has to tell us
    • Nordborg M, Taveré S (2002) Linkage disequilibrium: what history has to tell us. Trends Genet 18:83-90
    • (2002) Trends Genet , vol.18 , pp. 83-90
    • Nordborg, M.1    Taveré, S.2
  • 43
    • 1842539516 scopus 로고    scopus 로고
    • A simple correction for multiple testing for single-nucleotide polymorphisms in linkage disequilibrium with each other
    • Nyholt DR (2004) A simple correction for multiple testing for single-nucleotide polymorphisms in linkage disequilibrium with each other. Am J Hum Genet 74:765-769
    • (2004) Am J Hum Genet , vol.74 , pp. 765-769
    • Nyholt, D.R.1
  • 45
    • 0142059667 scopus 로고    scopus 로고
    • "Are we there yet?": Deciding when one has demonstrated specific genetic causation in complex diseases and quantitative traits
    • Page GP, George V, Go RC, Page PZ, Allison DB (2003) "Are we there yet?": deciding when one has demonstrated specific genetic causation in complex diseases and quantitative traits. Am J Hum Genet 73:711-719
    • (2003) Am J Hum Genet , vol.73 , pp. 711-719
    • Page, G.P.1    George, V.2    Go, R.C.3    Page, P.Z.4    Allison, D.B.5
  • 46
    • 85030740926 scopus 로고    scopus 로고
    • Shaking the tree: Mapping complex disease genes using linkage disequilibrium
    • in press
    • Palmer LJ, Cardon LR. Shaking the tree: mapping complex disease genes using linkage disequilibrium. Lancet (in press)
    • Lancet
    • Palmer, L.J.1    Cardon, L.R.2
  • 47
    • 0036138925 scopus 로고    scopus 로고
    • Efficiency of DNA pooling to estimate joint allele frequencies and measure linkage disequilibrium
    • Pfeiffer RM, Rutter JL, Gail MH, Struewing J, Gastwirth JL (2002) Efficiency of DNA pooling to estimate joint allele frequencies and measure linkage disequilibrium. Genet Epidemiol 22:94-102
    • (2002) Genet Epidemiol , vol.22 , pp. 94-102
    • Pfeiffer, R.M.1    Rutter, J.L.2    Gail, M.H.3    Struewing, J.4    Gastwirth, J.L.5
  • 48
    • 0034969437 scopus 로고    scopus 로고
    • Are rare variants responsible for susceptibility to complex diseases?
    • Pritchard JK (2001) Are rare variants responsible for susceptibility to complex diseases? Am J Hum Genet 69:124-137
    • (2001) Am J Hum Genet , vol.69 , pp. 124-137
    • Pritchard, J.K.1
  • 49
    • 0036799545 scopus 로고    scopus 로고
    • The allelic architecture of human disease genes: Common disease-common variant...or not?
    • Pritchard JK, Cox NJ (2002) The allelic architecture of human disease genes: common disease-common variant...or not? Hum Mol Genet 11:2417-2423
    • (2002) Hum Mol Genet , vol.11 , pp. 2417-2423
    • Pritchard, J.K.1    Cox, N.J.2
  • 51
    • 0035451780 scopus 로고    scopus 로고
    • On the allelic spectrum of human disease
    • Reich DE, Lander ES (2001) On the allelic spectrum of human disease. Trends Genet 17:502-510
    • (2001) Trends Genet , vol.17 , pp. 502-510
    • Reich, D.E.1    Lander, E.S.2
  • 52
    • 0141993292 scopus 로고    scopus 로고
    • Allowing for genotyping error in analysis of unmatched case-control studies
    • Rice KM, Holmans P (2003) Allowing for genotyping error in analysis of unmatched case-control studies. Ann Hum Genet 67:165-174
    • (2003) Ann Hum Genet , vol.67 , pp. 165-174
    • Rice, K.M.1    Holmans, P.2
  • 53
    • 0025019555 scopus 로고
    • Linkage strategies for genetically complex traits. I. Multilocus models
    • Risch N (1990) Linkage strategies for genetically complex traits. I. Multilocus models. Am J Hum Genet 46:222-228
    • (1990) Am J Hum Genet , vol.46 , pp. 222-228
    • Risch, N.1
  • 54
    • 0029741063 scopus 로고    scopus 로고
    • The future of genetic studies of complex human diseases
    • Risch N, Merikangas K (1996) The future of genetic studies of complex human diseases. Science 273:1616-1617
    • (1996) Science , vol.273 , pp. 1616-1617
    • Risch, N.1    Merikangas, K.2
  • 55
    • 0037786658 scopus 로고    scopus 로고
    • False discovery rate in linkage and association genome screens for complex disorders
    • Sabatti C, Service S, Freimer N (2003) False discovery rate in linkage and association genome screens for complex disorders. Genetics 164:829-833
    • (2003) Genetics , vol.164 , pp. 829-833
    • Sabatti, C.1    Service, S.2    Freimer, N.3
  • 56
    • 0042859846 scopus 로고    scopus 로고
    • Optimal two-stage genotyping in population-based association studies
    • Satagopan JM, Elston RC (2003) Optimal two-stage genotyping in population-based association studies. Genet Epideraiol 25:149-157
    • (2003) Genet Epideraiol , vol.25 , pp. 149-157
    • Satagopan, J.M.1    Elston, R.C.2
  • 57
    • 4444317393 scopus 로고    scopus 로고
    • Two-stage designs for gene-disease association studies with sample size constraints
    • Satagopan JM, Venkatraman ES, Begg CB (2004) Two-stage designs for gene-disease association studies with sample size constraints. Biometrics 60:589-597
    • (2004) Biometrics , vol.60 , pp. 589-597
    • Satagopan, J.M.1    Venkatraman, E.S.2    Begg, C.B.3
  • 59
    • 0036155283 scopus 로고    scopus 로고
    • Score tests for association between traits and haplotypes when linkage phase is ambiguous
    • Schaid DJ, Rowland CM, Tines DE, Jacobson RM, Poland GA (2002) Score tests for association between traits and haplotypes when linkage phase is ambiguous. Am J Hum Genet 70:425-434
    • (2002) Am J Hum Genet , vol.70 , pp. 425-434
    • Schaid, D.J.1    Rowland, C.M.2    Tines, D.E.3    Jacobson, R.M.4    Poland, G.A.5
  • 62
    • 0037020214 scopus 로고    scopus 로고
    • Sequence first. Ask questions later
    • Sidow A (2002) Sequence first. Ask questions later. Cell 111: 13-16
    • (2002) Cell , vol.111 , pp. 13-16
    • Sidow, A.1
  • 63
    • 0027415108 scopus 로고
    • Novel association approach for determining the genetic predisposition to schizophrenia: Case-control resource and testing of a candidate gene
    • Sobell JL, Heston LL, Sommer SS (1993) Novel association approach for determining the genetic predisposition to schizophrenia: case-control resource and testing of a candidate gene. Am J Med Genet 48:28-35
    • (1993) Am J Med Genet , vol.48 , pp. 28-35
    • Sobell, J.L.1    Heston, L.L.2    Sommer, S.S.3
  • 64
    • 0042424602 scopus 로고    scopus 로고
    • Statistical significance for genomewide studies
    • Storey JD, Tibshirani R (2003) Statistical significance for genomewide studies. Proc Natl Acad Sci USA 100:9440-9445
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 9440-9445
    • Storey, J.D.1    Tibshirani, R.2
  • 66
    • 0036255811 scopus 로고    scopus 로고
    • Opinion: Candidate-gene approaches for studying complex genetic traits: Practical considerations
    • Tabor HK, Risch NJ, Myers RM (2002) Opinion: candidate-gene approaches for studying complex genetic traits: practical considerations. Nat Rev Genet 3:391-397
    • (2002) Nat Rev Genet , vol.3 , pp. 391-397
    • Tabor, H.K.1    Risch, N.J.2    Myers, R.M.3
  • 68
    • 0042120989 scopus 로고    scopus 로고
    • PARSESNP: A tool for the analysis of nucleotide polymorphisms
    • Taylor NE, Greene EA (2003) PARSESNP: A tool for the analysis of nucleotide polymorphisms. Nucleic Acids Res 31: 3808-11
    • (2003) Nucleic Acids Res , vol.31 , pp. 3808-3811
    • Taylor, N.E.1    Greene, E.A.2
  • 69
    • 0036277684 scopus 로고    scopus 로고
    • Point: Population stratification: A problem for case-control studies of candidate gene associations?
    • Thomas DC, Witte JS (2002) Point: Population stratification: A problem for case-control studies of candidate gene associations? Cancer Epidemiol Biomarkers Prev 11:505-512
    • (2002) Cancer Epidemiol Biomarkers Prev , vol.11 , pp. 505-512
    • Thomas, D.C.1    Witte, J.S.2
  • 70
    • 10044277900 scopus 로고    scopus 로고
    • Two-stage sampling designs for gene association studies
    • Thomas DC, Xie R, Gebregziabher M (2004) Two-stage sampling designs for gene association studies. Genet Epidemiol 27:401-414
    • (2004) Genet Epidemiol , vol.27 , pp. 401-414
    • Thomas, D.C.1    Xie, R.2    Gebregziabher, M.3
  • 71
    • 0345269986 scopus 로고    scopus 로고
    • On the identification of disease mutations by the analysis of haplotype similarity and goodness of fit
    • Tzeng JY, Devlin B, Wasserman L, Roeder K (2003) On the identification of disease mutations by the analysis of haplotype similarity and goodness of fit. Am J Hum Genet 72: 891-902
    • (2003) Am J Hum Genet , vol.72 , pp. 891-902
    • Tzeng, J.Y.1    Devlin, B.2    Wasserman, L.3    Roeder, K.4
  • 72
    • 1642588401 scopus 로고    scopus 로고
    • A framework for controlling false discovery rates and minimizing the amount of genotyping in the search for disease mutations
    • van den Oord EJ, Sullivan PF (2003) A framework for controlling false discovery rates and minimizing the amount of genotyping in the search for disease mutations. Hum Hered 56:188-199
    • (2003) Hum Hered , vol.56 , pp. 188-199
    • Van Den Oord, E.J.1    Sullivan, P.F.2
  • 73
    • 1642295096 scopus 로고    scopus 로고
    • Assessing the probability that a positive report is false: An approach for molecular epidemiology studies
    • Wacholder S, Chanock S, Garcia-Closas M, El Ghormli L, Rothman N (2004) Assessing the probability that a positive report is false: an approach for molecular epidemiology studies. J Natl Cancer Inst 96:434-442
    • (2004) J Natl Cancer Inst , vol.96 , pp. 434-442
    • Wacholder, S.1    Chanock, S.2    Garcia-Closas, M.3    El Ghormli, L.4    Rothman, N.5
  • 74
    • 0034686618 scopus 로고    scopus 로고
    • Population stratification in epidemiologic studies of common genetic variants and cancer: Quantification of bias
    • Wacholder S, Rothman N, Caporaso N (2000) Population stratification in epidemiologic studies of common genetic variants and cancer: quantification of bias. J Natl Cancer Inst 92:1151-8
    • (2000) J Natl Cancer Inst , vol.92 , pp. 1151-1158
    • Wacholder, S.1    Rothman, N.2    Caporaso, N.3
  • 75
    • 0036275761 scopus 로고    scopus 로고
    • Counterpoint: Bias from population stratification is not a major threat to the validity of conclusions from epidemiologic studies of common polymorphisms and cancer
    • Wacholder S, Rothman N, Caporaso N (2002) Counterpoint: Bias from population stratification is not a major threat to the validity of conclusions from epidemiologic studies of common polymorphisms and cancer. Cancer Epidemiol Biomarkers Prev 11:513-520
    • (2002) Cancer Epidemiol Biomarkers Prev , vol.11 , pp. 513-520
    • Wacholder, S.1    Rothman, N.2    Caporaso, N.3
  • 76
    • 0037224762 scopus 로고    scopus 로고
    • Association mapping of complex diseases in linked regions: Estimation of genetic effects and feasibility of testing rare variants
    • Wang WY, Cordell HJ, Todd JA (2003) Association mapping of complex diseases in linked regions: estimation of genetic effects and feasibility of testing rare variants. Genet Epidemiol 24:36-43
    • (2003) Genet Epidemiol , vol.24 , pp. 36-43
    • Wang, W.Y.1    Cordell, H.J.2    Todd, J.A.3
  • 77
    • 13144265739 scopus 로고    scopus 로고
    • Genome-wide association studies: Theoretical and practical concerns
    • Wang WYS, Barratt BJ, Clayton DG, Todd JA (2005) Genome-wide association studies: theoretical and practical concerns. Nat Rev Genet 6:109-118
    • (2005) Nat Rev Genet , vol.6 , pp. 109-118
    • Wang, W.Y.S.1    Barratt, B.J.2    Clayton, D.G.3    Todd, J.A.4
  • 79
    • 0033561180 scopus 로고    scopus 로고
    • Asymptotic bias and efficiency in case-control studies of candidate genes and gene-environment interactions: Basic family designs
    • Witte JS, Gauderman WJ, Thomas DC (1999) Asymptotic bias and efficiency in case-control studies of candidate genes and gene-environment interactions: Basic family designs. Am J Epidemiol 148:693-705
    • (1999) Am J Epidemiol , vol.148 , pp. 693-705
    • Witte, J.S.1    Gauderman, W.J.2    Thomas, D.C.3
  • 80
    • 2642527702 scopus 로고    scopus 로고
    • Many amino acid substitution variants identified in DNA repair genes during human population screenings are predicted to impact protein function
    • Xi T, Jones IM, Mohrenweiser HW (2004) Many amino acid substitution variants identified in DNA repair genes during human population screenings are predicted to impact protein function. Genomics 83:970-979
    • (2004) Genomics , vol.83 , pp. 970-979
    • Xi, T.1    Jones, I.M.2    Mohrenweiser, H.W.3
  • 81
    • 0036284203 scopus 로고    scopus 로고
    • Testing association of statistically inferred haplotypes with discrete and continuous traits in samples of unrelated individuals
    • Zaykin DV, Westfall PH, Young SS, Karnoub MA, Wagner MJ, Ehm MG (2002) Testing association of statistically inferred haplotypes with discrete and continuous traits in samples of unrelated individuals. Hum Hered 53:79-91
    • (2002) Hum Hered , vol.53 , pp. 79-91
    • Zaykin, D.V.1    Westfall, P.H.2    Young, S.S.3    Karnoub, M.A.4    Wagner, M.J.5    Ehm, M.G.6
  • 82
    • 1542405868 scopus 로고    scopus 로고
    • An evolutionary perspective on single-nucleotide polymorphism screening in molecular cancer epidemiology
    • Zhu Y, Spitz MR, Amos CI, Lin J, Schabath MB, Wu X (2004) An evolutionary perspective on single-nucleotide polymorphism screening in molecular cancer epidemiology. Cancer Res 64:2251-2257
    • (2004) Cancer Res , vol.64 , pp. 2251-2257
    • Zhu, Y.1    Spitz, M.R.2    Amos, C.I.3    Lin, J.4    Schabath, M.B.5    Wu, X.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.