-
1
-
-
0037168512
-
Association testing by DNA pooling: An effective initial screen
-
Bansal A, van den Boom D, Kammerer S, Honisch C, Adam G, Cantor CR, Kleyn P, Braun A (2002) Association testing by DNA pooling: an effective initial screen. Proc Natl Acad Sci USA 99:16871-16874
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 16871-16874
-
-
Bansal, A.1
Van Den Boom, D.2
Kammerer, S.3
Honisch, C.4
Adam, G.5
Cantor, C.R.6
Kleyn, P.7
Braun, A.8
-
2
-
-
0036866635
-
Identification of the sources of error in allele frequency estimations from pooled DNA indicates an optimal experimental design
-
Barratt BJ, Payne F, Rance HE, Nutland S, Todd JA, Clayton DG (2002) Identification of the sources of error in allele frequency estimations from pooled DNA indicates an optimal experimental design. Ann Hum Genet 66:393-405
-
(2002)
Ann Hum Genet
, vol.66
, pp. 393-405
-
-
Barratt, B.J.1
Payne, F.2
Rance, H.E.3
Nutland, S.4
Todd, J.A.5
Clayton, D.G.6
-
3
-
-
2542542256
-
Ultraconserved elements in the human genome
-
Bejerano G, Pheasant M, Makunin I, Stephen S, Kent WJ, Mattick JS, Haussler D (2004) Ultraconserved elements in the human genome. Science 304:1321-1325
-
(2004)
Science
, vol.304
, pp. 1321-1325
-
-
Bejerano, G.1
Pheasant, M.2
Makunin, I.3
Stephen, S.4
Kent, W.J.5
Mattick, J.S.6
Haussler, D.7
-
4
-
-
0001677717
-
Controlling the false discovery rate: A practical and powerful approach to multiple testing
-
Benjamini Y, Hochberg Y (1995) Controlling the false discovery rate: a practical and powerful approach to multiple testing. J R Stat Soc B 57:289-300
-
(1995)
J R Stat Soc B
, vol.57
, pp. 289-300
-
-
Benjamini, Y.1
Hochberg, Y.2
-
5
-
-
0028070381
-
Limits of resolution of genetic linkage studies: Implications for the positional cloning of human disease genes
-
Boehnke M (1994) Limits of resolution of genetic linkage studies: implications for the positional cloning of human disease genes. Am J Hum Genet 55:379-390
-
(1994)
Am J Hum Genet
, vol.55
, pp. 379-390
-
-
Boehnke, M.1
-
6
-
-
0037373275
-
Discovering genotypes underlying human phenotypes: Past successes for mendelian disease, future approaches for complex disease
-
Botstein D, Risch N (2003) Discovering genotypes underlying human phenotypes: past successes for mendelian disease, future approaches for complex disease. Nat Genet 33:228-237
-
(2003)
Nat Genet
, vol.33
, pp. 228-237
-
-
Botstein, D.1
Risch, N.2
-
7
-
-
0035257236
-
Association study designs for complex diseases
-
Cardon LR, Bell JI (2001) Association study designs for complex diseases. Nat Rev Genet 2:91-99
-
(2001)
Nat Rev Genet
, vol.2
, pp. 91-99
-
-
Cardon, L.R.1
Bell, J.I.2
-
8
-
-
0037442092
-
Population stratification and spurious allelic association
-
Cardon LR, Palmer LJ (2003) Population stratification and spurious allelic association. Lancet 361:598-604
-
(2003)
Lancet
, vol.361
, pp. 598-604
-
-
Cardon, L.R.1
Palmer, L.J.2
-
9
-
-
0034139518
-
Mining for SNPs: Putting the common variants-common disease hypothesis to the test
-
Cargill M, Daley GQ (2000) Mining for SNPs: putting the common variants-common disease hypothesis to the test. Pharmacogenomics 1:27-37
-
(2000)
Pharmacogenomics
, vol.1
, pp. 27-37
-
-
Cargill, M.1
Daley, G.Q.2
-
10
-
-
2642583283
-
Mapping complex disease loci in whole-genome association studies
-
Carlson CS, Eberle MA, Kruglyak L, Nickerson DA (2004) Mapping complex disease loci in whole-genome association studies. Nature 429:446-452
-
(2004)
Nature
, vol.429
, pp. 446-452
-
-
Carlson, C.S.1
Eberle, M.A.2
Kruglyak, L.3
Nickerson, D.A.4
-
11
-
-
0344091561
-
Additional SNPs and linkage-disequilibrium analyses are necessary for whole-genome association studies in humans
-
Carlson CS, Eberle MA, Rieder MJ, Smith JD, Kruglyak L, Nickerson DA (2003) Additional SNPs and linkage-disequilibrium analyses are necessary for whole-genome association studies in humans. Nat Genet 33:518-521
-
(2003)
Nat Genet
, vol.33
, pp. 518-521
-
-
Carlson, C.S.1
Eberle, M.A.2
Rieder, M.J.3
Smith, J.D.4
Kruglyak, L.5
Nickerson, D.A.6
-
12
-
-
0035922669
-
Epidemiological methods for studying genes and environmental factors in complex diseases
-
Clayton DG, McKeigue PM (2001) Epidemiological methods for studying genes and environmental factors in complex diseases. Lancet 358:1357-1360
-
(2001)
Lancet
, vol.358
, pp. 1357-1360
-
-
Clayton, D.G.1
McKeigue, P.M.2
-
13
-
-
0030688004
-
Variations on a theme: Cataloging human DNA sequence variation
-
Collins FS, Guyer MS, Charkravarti A (1997) Variations on a theme: cataloging human DNA sequence variation. Science 278:1580-1581
-
(1997)
Science
, vol.278
, pp. 1580-1581
-
-
Collins, F.S.1
Guyer, M.S.2
Charkravarti, A.3
-
14
-
-
0035528921
-
Genomic control, a new approach to genetic-based association studies
-
Devlin B, Roeder K, Wasserman L (2001) Genomic control, a new approach to genetic-based association studies. Theor Pop Biol 60:155-160
-
(2001)
Theor Pop Biol
, vol.60
, pp. 155-160
-
-
Devlin, B.1
Roeder, K.2
Wasserman, L.3
-
15
-
-
0035992248
-
Empirical Bayes methods and false discovery rates for microarrays
-
Efron B, Tibshirani R (2002) Empirical Bayes methods and false discovery rates for microarrays. Genet Epidemiol 23: 70-86
-
(2002)
Genet Epidemiol
, vol.23
, pp. 70-86
-
-
Efron, B.1
Tibshirani, R.2
-
16
-
-
7444260846
-
The ENCODE (ENCyclopedia of DNA Elements) Project
-
ENCODE Project Consortium (2004) The ENCODE (ENCyclopedia Of DNA Elements) Project. Science 306:636-640
-
(2004)
Science
, vol.306
, pp. 636-640
-
-
-
17
-
-
8644235804
-
Multiple rare variants in different genes account for multifactorial inherited susceptibility to colorectal adenomas
-
Fearnhead NS, Wilding JL, Winney B, Tonks S, Bartlett S, Bicknell DC, Tomlinson IP, Mortensen NJ, Bodmer WF (2004) Multiple rare variants in different genes account for multifactorial inherited susceptibility to colorectal adenomas. Proc Natl Acad Sci USA 101:15992-15997
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 15992-15997
-
-
Fearnhead, N.S.1
Wilding, J.L.2
Winney, B.3
Tonks, S.4
Bartlett, S.5
Bicknell, D.C.6
Tomlinson, I.P.7
Mortensen, N.J.8
Bodmer, W.F.9
-
18
-
-
12144285594
-
Assessing the impact of population stratification on genetic association studies
-
Freedman ML, Reich D, Penney KL, McDonald GJ, Mignault AA, Patterson N, Gabriel SB, Topol EJ, Smoller JW, Pato CN, Pato MT, Petryshen TL, Kolonel LN, Lander ES, Sklar P, Henderson B, Hirschhorn JN, Altshuler D (2004) Assessing the impact of population stratification on genetic association studies. Nat Genet 36:388-393
-
(2004)
Nat Genet
, vol.36
, pp. 388-393
-
-
Freedman, M.L.1
Reich, D.2
Penney, K.L.3
McDonald, G.J.4
Mignault, A.A.5
Patterson, N.6
Gabriel, S.B.7
Topol, E.J.8
Smoller, J.W.9
Pato, C.N.10
Pato, M.T.11
Petryshen, T.L.12
Kolonel, L.N.13
Lander, E.S.14
Sklar, P.15
Henderson, B.16
Hirschhorn, J.N.17
Altshuler, D.18
-
19
-
-
79959503826
-
The International HapMap Project
-
Gibbs RA, Belmont JW, Hardenbol P, Willis TD, Yu F, Yang H, Ch'ang LY, et al (2003) The International HapMap Project. Nature 426:789-796
-
(2003)
Nature
, vol.426
, pp. 789-796
-
-
Gibbs, R.A.1
Belmont, J.W.2
Hardenbol, P.3
Willis, T.D.4
Yu, F.5
Yang, H.6
Ch'ang, L.Y.7
-
20
-
-
0034917944
-
A transmission/disequilibrium test that allows for genotyping errors in the analysis of single-nucleotide polymorphism data
-
Gordon D, Heath SC, Liu X, Ott J (2001) A transmission/disequilibrium test that allows for genotyping errors in the analysis of single-nucleotide polymorphism data. Am J Hum Genet 69:371-380
-
(2001)
Am J Hum Genet
, vol.69
, pp. 371-380
-
-
Gordon, D.1
Heath, S.C.2
Liu, X.3
Ott, J.4
-
21
-
-
18544362940
-
Increasing power for tests of genetic association in the presence of phenotype and/or genotype error by use of double-sampling
-
Gordon D, Yang Y, Haynes C, Finch SJ, Mendell NR, Brown AM, Haroutunian V (2004) Increasing power for tests of genetic association in the presence of phenotype and/or genotype error by use of double-sampling. Stat Appl Genet Mol Biol 3:1-35
-
(2004)
Stat Appl Genet Mol Biol
, vol.3
, pp. 1-35
-
-
Gordon, D.1
Yang, Y.2
Haynes, C.3
Finch, S.J.4
Mendell, N.R.5
Brown, A.M.6
Haroutunian, V.7
-
22
-
-
19944401078
-
Incorporating individual error rate into association test of unmatched case-control design
-
Hao K, Wang X (2004) Incorporating individual error rate into association test of unmatched case-control design. Hum Hered 58:154-163
-
(2004)
Hum Hered
, vol.58
, pp. 154-163
-
-
Hao, K.1
Wang, X.2
-
23
-
-
13844313862
-
Whole-genome patterns of common DNA variation in three human populations
-
Hinds DA, Stuve LL, Nilsen GB, Halperin E, Eskin E, Ballinger DG, Frazer KA, Cox DR (2005) Whole-genome patterns of common DNA variation in three human populations. Science 307:1072-1079
-
(2005)
Science
, vol.307
, pp. 1072-1079
-
-
Hinds, D.A.1
Stuve, L.L.2
Nilsen, G.B.3
Halperin, E.4
Eskin, E.5
Ballinger, D.G.6
Frazer, K.A.7
Cox, D.R.8
-
24
-
-
13144306071
-
Genome-wide association studies for common disease and complex traits
-
Hirschhorn JN, Daly MJ (2005) Genome-wide association studies for common disease and complex traits. Nat Rev Genet 6:95-108
-
(2005)
Nat Rev Genet
, vol.6
, pp. 95-108
-
-
Hirschhorn, J.N.1
Daly, M.J.2
-
25
-
-
4444291843
-
Detection of large-scale variation in the human genome
-
Iafrate AJ, Feuk L, Rivera MN, Listewnik ML, Donahoe PK, Qi Y, Scherer SW, Lee C (2004) Detection of large-scale variation in the human genome. Nat Genet 36:949-951
-
(2004)
Nat Genet
, vol.36
, pp. 949-951
-
-
Iafrate, A.J.1
Feuk, L.2
Rivera, M.N.3
Listewnik, M.L.4
Donahoe, P.K.5
Qi, Y.6
Scherer, S.W.7
Lee, C.8
-
26
-
-
20244380171
-
Complement factor H polymorphism in age-related macular degeneration
-
Klein RJ, Zeiss C, Chew EY, Tsai J-Y, Sackler RS, Haynes C, Henning AK, SanGiovanni JP, Mane SM, Mayne ST, Bracken MB, Ferns FL, Ott J, Barnstable C, Hoh J (2005) Complement factor H polymorphism in age-related macular degeneration. Science 308:385-389
-
(2005)
Science
, vol.308
, pp. 385-389
-
-
Klein, R.J.1
Zeiss, C.2
Chew, E.Y.3
Tsai, J.-Y.4
Sackler, R.S.5
Haynes, C.6
Henning, A.K.7
Sangiovanni, J.P.8
Mane, S.M.9
Mayne, S.T.10
Bracken, M.B.11
Ferns, F.L.12
Ott, J.13
Barnstable, C.14
Hoh, J.15
-
28
-
-
0042888663
-
Estimation of the inbreeding coefficient through use of genomic data
-
Leutenegger AL, Prum B, Genin E, Verny C, Lemainque A, Clerget-Darpoux F, Thompson EA (2003) Estimation of the inbreeding coefficient through use of genomic data. Am J Hum Genet 73:516-523
-
(2003)
Am J Hum Genet
, vol.73
, pp. 516-523
-
-
Leutenegger, A.L.1
Prum, B.2
Genin, E.3
Verny, C.4
Lemainque, A.5
Clerget-Darpoux, F.6
Thompson, E.A.7
-
29
-
-
6344233909
-
Finding haplotype tagging SNPs by use of principal components analysis
-
Lin Z, Altman RB (2004) Finding haplotype tagging SNPs by use of principal components analysis. Am J Hum Genet 75: 850-861
-
(2004)
Am J Hum Genet
, vol.75
, pp. 850-861
-
-
Lin, Z.1
Altman, R.B.2
-
30
-
-
13144282294
-
Exhaustive allelic transmission disequilibrium tests as a new approach to genomewide association studies
-
Lin S, Chakravarti A, Cutler DJ (2004) Exhaustive allelic transmission disequilibrium tests as a new approach to genomewide association studies. Nat Genet 36:1181-1188
-
(2004)
Nat Genet
, vol.36
, pp. 1181-1188
-
-
Lin, S.1
Chakravarti, A.2
Cutler, D.J.3
-
31
-
-
6344267228
-
Pattern of sequence variation across 213 environmental response genes
-
Livingston RJ, von Niederhausern A, Jegga AG, Crawford DC, Carlson CS, Rieder MJ, Gowrisankar S, Aronow BJ, Weiss RB, Nickerson DA (2004) Pattern of sequence variation across 213 environmental response genes. Genome Res 14: 1821-1831
-
(2004)
Genome Res
, vol.14
, pp. 1821-1831
-
-
Livingston, R.J.1
Von Niederhausern, A.2
Jegga, A.G.3
Crawford, D.C.4
Carlson, C.S.5
Rieder, M.J.6
Gowrisankar, S.7
Aronow, B.J.8
Weiss, R.B.9
Nickerson, D.A.10
-
32
-
-
0037312921
-
Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease
-
Lohmueller KE, Pearce CL, Pike MC, Lander ES, Hirschhorn JN (2003) Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease. Nat Genet 33:177-182
-
(2003)
Nat Genet
, vol.33
, pp. 177-182
-
-
Lohmueller, K.E.1
Pearce, C.L.2
Pike, M.C.3
Lander, E.S.4
Hirschhorn, J.N.5
-
33
-
-
3242768295
-
Cost-effective analysis of candidate genes using htSNPs: A staged approach
-
Lowe CE, Cooper JD, Chapman JM, Barratt BJ, Twells RC, Green EA, Savage DA, Guja C, Ionescu-Tirgoviste C, Tuomilehto-Wolf E, Tuomilehto J, Todd JA, Clayton DG (2004) Cost-effective analysis of candidate genes using htSNPs: a staged approach. Genes Immun 5:301-305
-
(2004)
Genes Immun
, vol.5
, pp. 301-305
-
-
Lowe, C.E.1
Cooper, J.D.2
Chapman, J.M.3
Barratt, B.J.4
Twells, R.C.5
Green, E.A.6
Savage, D.A.7
Guja, C.8
Ionescu-Tirgoviste, C.9
Tuomilehto-Wolf, E.10
Tuomilehto, J.11
Todd, J.A.12
Clayton, D.G.13
-
34
-
-
0028796840
-
Concordance for Hodgkin's disease in identical twins suggesting genetic susceptibility to the young-adult form of the disease
-
Mack TM, Cozen W, Shibata DK, Weiss LM, Nathwani BN, Hernandez AM, Taylor CR, Hamilton AS, Deapen DM, Rappaport EB (1995) Concordance for Hodgkin's disease in identical twins suggesting genetic susceptibility to the young-adult form of the disease. N Engl J Med 332:413-418
-
(1995)
N Engl J Med
, vol.332
, pp. 413-418
-
-
Mack, T.M.1
Cozen, W.2
Shibata, D.K.3
Weiss, L.M.4
Nathwani, B.N.5
Hernandez, A.M.6
Taylor, C.R.7
Hamilton, A.S.8
Deapen, D.M.9
Rappaport, E.B.10
-
35
-
-
16844366786
-
Genome-wide strategies for detecting multiple loci that influence complex diseases
-
Marchini J, Donnelly P, Cardon LR (2005) Genome-wide strategies for detecting multiple loci that influence complex diseases. Nat Genet 37:413-417
-
(2005)
Nat Genet
, vol.37
, pp. 413-417
-
-
Marchini, J.1
Donnelly, P.2
Cardon, L.R.3
-
36
-
-
0037371453
-
Undetected genotyping errors cause apparent overtransmission of common alleles in the transmission/disequilibrium test
-
Mitchell AA, Cutler DJ, Chakravarti A (2003) Undetected genotyping errors cause apparent overtransmission of common alleles in the transmission/ disequilibrium test. Am J Hum Genet 72:598-610
-
(2003)
Am J Hum Genet
, vol.72
, pp. 598-610
-
-
Mitchell, A.A.1
Cutler, D.J.2
Chakravarti, A.3
-
37
-
-
4043128071
-
Genetic analysis of genome-wide variation in human gene expression
-
Morley M, Molony CM, Weber TM, Devlin JL, Ewens KG, Spielman RS, Cheung VG (2004) Genetic analysis of genome-wide variation in human gene expression. Nature 430: 743-747
-
(2004)
Nature
, vol.430
, pp. 743-747
-
-
Morley, M.1
Molony, C.M.2
Weber, T.M.3
Devlin, J.L.4
Ewens, K.G.5
Spielman, R.S.6
Cheung, V.G.7
-
38
-
-
13844253254
-
Linkage disequilibrium patterns and tagSNP transferability among European populations
-
Mueller JC, Lohmussaar E, Magi R, Remm M, Bettecken T, Lichtner P, Biskup S, Illig T, Pfeufer A, Luedemann J, Schreiber S, Pramstaller P, Pichler I, Romeo G, Gaddi A, Testa A, Wichmann HE, Metspalu A, Meitinger T (2005) Linkage disequilibrium patterns and tagSNP transferability among European populations. Am J Hum Genet 76:387-398
-
(2005)
Am J Hum Genet
, vol.76
, pp. 387-398
-
-
Mueller, J.C.1
Lohmussaar, E.2
Magi, R.3
Remm, M.4
Bettecken, T.5
Lichtner, P.6
Biskup, S.7
Illig, T.8
Pfeufer, A.9
Luedemann, J.10
Schreiber, S.11
Pramstaller, P.12
Pichler, I.13
Romeo, G.14
Gaddi, A.15
Testa, A.16
Wichmann, H.E.17
Metspalu, A.18
Meitinger, T.19
-
39
-
-
4143134235
-
The future of association studies: Gene-based analysis and replication
-
Neale BM, Sham PC (2004) The future of association studies: gene-based analysis and replication. Am J Hum Genet 75: 353-362
-
(2004)
Am J Hum Genet
, vol.75
, pp. 353-362
-
-
Neale, B.M.1
Sham, P.C.2
-
41
-
-
0043122919
-
SIFT: Predicting amino acid changes that affect protein function
-
Ng PC, Henikoff S (2003) SIFT: Predicting amino acid changes that affect protein function. Nucleic Acids Res 31:3812-3814
-
(2003)
Nucleic Acids Res
, vol.31
, pp. 3812-3814
-
-
Ng, P.C.1
Henikoff, S.2
-
42
-
-
0036468808
-
Linkage disequilibrium: What history has to tell us
-
Nordborg M, Taveré S (2002) Linkage disequilibrium: what history has to tell us. Trends Genet 18:83-90
-
(2002)
Trends Genet
, vol.18
, pp. 83-90
-
-
Nordborg, M.1
Taveré, S.2
-
43
-
-
1842539516
-
A simple correction for multiple testing for single-nucleotide polymorphisms in linkage disequilibrium with each other
-
Nyholt DR (2004) A simple correction for multiple testing for single-nucleotide polymorphisms in linkage disequilibrium with each other. Am J Hum Genet 74:765-769
-
(2004)
Am J Hum Genet
, vol.74
, pp. 765-769
-
-
Nyholt, D.R.1
-
44
-
-
18744407845
-
Functional SNPs in the lymphotoxin-alpha gene that are associated with susceptibility to myocardial infarction
-
Ozaki K, Ohnishi Y, Iida A, Sekine A, Yamada R, Tsunoda T, Sato H, Hori M, Nakamura Y, Tanaka T (2002) Functional SNPs in the lymphotoxin-alpha gene that are associated with susceptibility to myocardial infarction. Nat Genet 32:650-654
-
(2002)
Nat Genet
, vol.32
, pp. 650-654
-
-
Ozaki, K.1
Ohnishi, Y.2
Iida, A.3
Sekine, A.4
Yamada, R.5
Tsunoda, T.6
Sato, H.7
Hori, M.8
Nakamura, Y.9
Tanaka, T.10
-
45
-
-
0142059667
-
"Are we there yet?": Deciding when one has demonstrated specific genetic causation in complex diseases and quantitative traits
-
Page GP, George V, Go RC, Page PZ, Allison DB (2003) "Are we there yet?": deciding when one has demonstrated specific genetic causation in complex diseases and quantitative traits. Am J Hum Genet 73:711-719
-
(2003)
Am J Hum Genet
, vol.73
, pp. 711-719
-
-
Page, G.P.1
George, V.2
Go, R.C.3
Page, P.Z.4
Allison, D.B.5
-
46
-
-
85030740926
-
Shaking the tree: Mapping complex disease genes using linkage disequilibrium
-
in press
-
Palmer LJ, Cardon LR. Shaking the tree: mapping complex disease genes using linkage disequilibrium. Lancet (in press)
-
Lancet
-
-
Palmer, L.J.1
Cardon, L.R.2
-
47
-
-
0036138925
-
Efficiency of DNA pooling to estimate joint allele frequencies and measure linkage disequilibrium
-
Pfeiffer RM, Rutter JL, Gail MH, Struewing J, Gastwirth JL (2002) Efficiency of DNA pooling to estimate joint allele frequencies and measure linkage disequilibrium. Genet Epidemiol 22:94-102
-
(2002)
Genet Epidemiol
, vol.22
, pp. 94-102
-
-
Pfeiffer, R.M.1
Rutter, J.L.2
Gail, M.H.3
Struewing, J.4
Gastwirth, J.L.5
-
48
-
-
0034969437
-
Are rare variants responsible for susceptibility to complex diseases?
-
Pritchard JK (2001) Are rare variants responsible for susceptibility to complex diseases? Am J Hum Genet 69:124-137
-
(2001)
Am J Hum Genet
, vol.69
, pp. 124-137
-
-
Pritchard, J.K.1
-
49
-
-
0036799545
-
The allelic architecture of human disease genes: Common disease-common variant...or not?
-
Pritchard JK, Cox NJ (2002) The allelic architecture of human disease genes: common disease-common variant...or not? Hum Mol Genet 11:2417-2423
-
(2002)
Hum Mol Genet
, vol.11
, pp. 2417-2423
-
-
Pritchard, J.K.1
Cox, N.J.2
-
51
-
-
0035451780
-
On the allelic spectrum of human disease
-
Reich DE, Lander ES (2001) On the allelic spectrum of human disease. Trends Genet 17:502-510
-
(2001)
Trends Genet
, vol.17
, pp. 502-510
-
-
Reich, D.E.1
Lander, E.S.2
-
52
-
-
0141993292
-
Allowing for genotyping error in analysis of unmatched case-control studies
-
Rice KM, Holmans P (2003) Allowing for genotyping error in analysis of unmatched case-control studies. Ann Hum Genet 67:165-174
-
(2003)
Ann Hum Genet
, vol.67
, pp. 165-174
-
-
Rice, K.M.1
Holmans, P.2
-
53
-
-
0025019555
-
Linkage strategies for genetically complex traits. I. Multilocus models
-
Risch N (1990) Linkage strategies for genetically complex traits. I. Multilocus models. Am J Hum Genet 46:222-228
-
(1990)
Am J Hum Genet
, vol.46
, pp. 222-228
-
-
Risch, N.1
-
54
-
-
0029741063
-
The future of genetic studies of complex human diseases
-
Risch N, Merikangas K (1996) The future of genetic studies of complex human diseases. Science 273:1616-1617
-
(1996)
Science
, vol.273
, pp. 1616-1617
-
-
Risch, N.1
Merikangas, K.2
-
55
-
-
0037786658
-
False discovery rate in linkage and association genome screens for complex disorders
-
Sabatti C, Service S, Freimer N (2003) False discovery rate in linkage and association genome screens for complex disorders. Genetics 164:829-833
-
(2003)
Genetics
, vol.164
, pp. 829-833
-
-
Sabatti, C.1
Service, S.2
Freimer, N.3
-
56
-
-
0042859846
-
Optimal two-stage genotyping in population-based association studies
-
Satagopan JM, Elston RC (2003) Optimal two-stage genotyping in population-based association studies. Genet Epideraiol 25:149-157
-
(2003)
Genet Epideraiol
, vol.25
, pp. 149-157
-
-
Satagopan, J.M.1
Elston, R.C.2
-
57
-
-
4444317393
-
Two-stage designs for gene-disease association studies with sample size constraints
-
Satagopan JM, Venkatraman ES, Begg CB (2004) Two-stage designs for gene-disease association studies with sample size constraints. Biometrics 60:589-597
-
(2004)
Biometrics
, vol.60
, pp. 589-597
-
-
Satagopan, J.M.1
Venkatraman, E.S.2
Begg, C.B.3
-
58
-
-
0036188784
-
Two-stage designs for gene-disease association studies
-
Satagopan JM, Verbel DA, Venkatraman ES, Offit KE, Begg CB (2002) Two-stage designs for gene-disease association studies. Biometrics 58:163-170
-
(2002)
Biometrics
, vol.58
, pp. 163-170
-
-
Satagopan, J.M.1
Verbel, D.A.2
Venkatraman, E.S.3
Offit, K.E.4
Begg, C.B.5
-
59
-
-
0036155283
-
Score tests for association between traits and haplotypes when linkage phase is ambiguous
-
Schaid DJ, Rowland CM, Tines DE, Jacobson RM, Poland GA (2002) Score tests for association between traits and haplotypes when linkage phase is ambiguous. Am J Hum Genet 70:425-434
-
(2002)
Am J Hum Genet
, vol.70
, pp. 425-434
-
-
Schaid, D.J.1
Rowland, C.M.2
Tines, D.E.3
Jacobson, R.M.4
Poland, G.A.5
-
60
-
-
3242808027
-
Large-scale copy number polymorphism in the human genome
-
Sebat J, Lakshmi B, Troge J, Alexander J, Young J, Lundin P, Maner S, Massa H, Walker M, Chi M, Navin N, Lucito R, Healy J, Hicks J, Ye K, Reiner A, Gilliam TC, Trask B, Patterson N, Zetterberg A, Wigler M (2004) Large-scale copy number polymorphism in the human genome. Science 305:525-528
-
(2004)
Science
, vol.305
, pp. 525-528
-
-
Sebat, J.1
Lakshmi, B.2
Troge, J.3
Alexander, J.4
Young, J.5
Lundin, P.6
Maner, S.7
Massa, H.8
Walker, M.9
Chi, M.10
Navin, N.11
Lucito, R.12
Healy, J.13
Hicks, J.14
Ye, K.15
Reiner, A.16
Gilliam, T.C.17
Trask, B.18
Patterson, N.19
Zetterberg, A.20
Wigler, M.21
more..
-
61
-
-
0036844881
-
DNA pooling: A tool for large-scale association studies
-
Sham P, Bader JS, Craig I, O'Donovan M, Owen M (2002) DNA pooling: a tool for large-scale association studies. Nat Rev Genet 3:862-871
-
(2002)
Nat Rev Genet
, vol.3
, pp. 862-871
-
-
Sham, P.1
Bader, J.S.2
Craig, I.3
O'Donovan, M.4
Owen, M.5
-
62
-
-
0037020214
-
Sequence first. Ask questions later
-
Sidow A (2002) Sequence first. Ask questions later. Cell 111: 13-16
-
(2002)
Cell
, vol.111
, pp. 13-16
-
-
Sidow, A.1
-
63
-
-
0027415108
-
Novel association approach for determining the genetic predisposition to schizophrenia: Case-control resource and testing of a candidate gene
-
Sobell JL, Heston LL, Sommer SS (1993) Novel association approach for determining the genetic predisposition to schizophrenia: case-control resource and testing of a candidate gene. Am J Med Genet 48:28-35
-
(1993)
Am J Med Genet
, vol.48
, pp. 28-35
-
-
Sobell, J.L.1
Heston, L.L.2
Sommer, S.S.3
-
64
-
-
0042424602
-
Statistical significance for genomewide studies
-
Storey JD, Tibshirani R (2003) Statistical significance for genomewide studies. Proc Natl Acad Sci USA 100:9440-9445
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 9440-9445
-
-
Storey, J.D.1
Tibshirani, R.2
-
65
-
-
0142156650
-
Modeling and E-M estimation of haplotype-specific relative risks from genotype data for a case-control study of unrelated individuals
-
Stram DO, Pearce CL, Bretsky P, Freedman M, Hirschhorn JN, Altshuler D, Kolonel LN, Henderson BE, Thomas DC (2003) Modeling and E-M estimation of haplotype-specific relative risks from genotype data for a case-control study of unrelated individuals. Hum Hered 55:179-190
-
(2003)
Hum Hered
, vol.55
, pp. 179-190
-
-
Stram, D.O.1
Pearce, C.L.2
Bretsky, P.3
Freedman, M.4
Hirschhorn, J.N.5
Altshuler, D.6
Kolonel, L.N.7
Henderson, B.E.8
Thomas, D.C.9
-
66
-
-
0036255811
-
Opinion: Candidate-gene approaches for studying complex genetic traits: Practical considerations
-
Tabor HK, Risch NJ, Myers RM (2002) Opinion: candidate-gene approaches for studying complex genetic traits: practical considerations. Nat Rev Genet 3:391-397
-
(2002)
Nat Rev Genet
, vol.3
, pp. 391-397
-
-
Tabor, H.K.1
Risch, N.J.2
Myers, R.M.3
-
67
-
-
19944432946
-
Genetic structure, self-identified race/ethnicity, and confounding in case-control association studies
-
Tang H, Quertermous T, Rodriguez B, Kardia SL, Zhu X, Brown A, Pankow JS, Province MA, Hunt SC, Boerwinkle E, Schork NJ, Risch NJ (2004) Genetic structure, self-identified race/ethnicity, and confounding in case-control association studies. Am J Hum Genet 76:268-275
-
(2004)
Am J Hum Genet
, vol.76
, pp. 268-275
-
-
Tang, H.1
Quertermous, T.2
Rodriguez, B.3
Kardia, S.L.4
Zhu, X.5
Brown, A.6
Pankow, J.S.7
Province, M.A.8
Hunt, S.C.9
Boerwinkle, E.10
Schork, N.J.11
Risch, N.J.12
-
68
-
-
0042120989
-
PARSESNP: A tool for the analysis of nucleotide polymorphisms
-
Taylor NE, Greene EA (2003) PARSESNP: A tool for the analysis of nucleotide polymorphisms. Nucleic Acids Res 31: 3808-11
-
(2003)
Nucleic Acids Res
, vol.31
, pp. 3808-3811
-
-
Taylor, N.E.1
Greene, E.A.2
-
69
-
-
0036277684
-
Point: Population stratification: A problem for case-control studies of candidate gene associations?
-
Thomas DC, Witte JS (2002) Point: Population stratification: A problem for case-control studies of candidate gene associations? Cancer Epidemiol Biomarkers Prev 11:505-512
-
(2002)
Cancer Epidemiol Biomarkers Prev
, vol.11
, pp. 505-512
-
-
Thomas, D.C.1
Witte, J.S.2
-
70
-
-
10044277900
-
Two-stage sampling designs for gene association studies
-
Thomas DC, Xie R, Gebregziabher M (2004) Two-stage sampling designs for gene association studies. Genet Epidemiol 27:401-414
-
(2004)
Genet Epidemiol
, vol.27
, pp. 401-414
-
-
Thomas, D.C.1
Xie, R.2
Gebregziabher, M.3
-
71
-
-
0345269986
-
On the identification of disease mutations by the analysis of haplotype similarity and goodness of fit
-
Tzeng JY, Devlin B, Wasserman L, Roeder K (2003) On the identification of disease mutations by the analysis of haplotype similarity and goodness of fit. Am J Hum Genet 72: 891-902
-
(2003)
Am J Hum Genet
, vol.72
, pp. 891-902
-
-
Tzeng, J.Y.1
Devlin, B.2
Wasserman, L.3
Roeder, K.4
-
72
-
-
1642588401
-
A framework for controlling false discovery rates and minimizing the amount of genotyping in the search for disease mutations
-
van den Oord EJ, Sullivan PF (2003) A framework for controlling false discovery rates and minimizing the amount of genotyping in the search for disease mutations. Hum Hered 56:188-199
-
(2003)
Hum Hered
, vol.56
, pp. 188-199
-
-
Van Den Oord, E.J.1
Sullivan, P.F.2
-
73
-
-
1642295096
-
Assessing the probability that a positive report is false: An approach for molecular epidemiology studies
-
Wacholder S, Chanock S, Garcia-Closas M, El Ghormli L, Rothman N (2004) Assessing the probability that a positive report is false: an approach for molecular epidemiology studies. J Natl Cancer Inst 96:434-442
-
(2004)
J Natl Cancer Inst
, vol.96
, pp. 434-442
-
-
Wacholder, S.1
Chanock, S.2
Garcia-Closas, M.3
El Ghormli, L.4
Rothman, N.5
-
74
-
-
0034686618
-
Population stratification in epidemiologic studies of common genetic variants and cancer: Quantification of bias
-
Wacholder S, Rothman N, Caporaso N (2000) Population stratification in epidemiologic studies of common genetic variants and cancer: quantification of bias. J Natl Cancer Inst 92:1151-8
-
(2000)
J Natl Cancer Inst
, vol.92
, pp. 1151-1158
-
-
Wacholder, S.1
Rothman, N.2
Caporaso, N.3
-
75
-
-
0036275761
-
Counterpoint: Bias from population stratification is not a major threat to the validity of conclusions from epidemiologic studies of common polymorphisms and cancer
-
Wacholder S, Rothman N, Caporaso N (2002) Counterpoint: Bias from population stratification is not a major threat to the validity of conclusions from epidemiologic studies of common polymorphisms and cancer. Cancer Epidemiol Biomarkers Prev 11:513-520
-
(2002)
Cancer Epidemiol Biomarkers Prev
, vol.11
, pp. 513-520
-
-
Wacholder, S.1
Rothman, N.2
Caporaso, N.3
-
76
-
-
0037224762
-
Association mapping of complex diseases in linked regions: Estimation of genetic effects and feasibility of testing rare variants
-
Wang WY, Cordell HJ, Todd JA (2003) Association mapping of complex diseases in linked regions: estimation of genetic effects and feasibility of testing rare variants. Genet Epidemiol 24:36-43
-
(2003)
Genet Epidemiol
, vol.24
, pp. 36-43
-
-
Wang, W.Y.1
Cordell, H.J.2
Todd, J.A.3
-
78
-
-
0042121286
-
Genome-wide scan in a large complex pedigree with predominantly male schizophrenics from the island of Kosrae: Evidence for linkage to chromosome 2q
-
Wijsman EM, Rosenthal EA, Hall D, Blundell ML, Sobin C, Heath SC, Williams R, Brownstein MJ, Gogos JA, Karayiorgou M (2003) Genome-wide scan in a large complex pedigree with predominantly male schizophrenics from the island of Kosrae: evidence for linkage to chromosome 2q. Mol Psychiatry 8:695-705, 643
-
(2003)
Mol Psychiatry
, vol.8
, pp. 695-705
-
-
Wijsman, E.M.1
Rosenthal, E.A.2
Hall, D.3
Blundell, M.L.4
Sobin, C.5
Heath, S.C.6
Williams, R.7
Brownstein, M.J.8
Gogos, J.A.9
Karayiorgou, M.10
-
79
-
-
0033561180
-
Asymptotic bias and efficiency in case-control studies of candidate genes and gene-environment interactions: Basic family designs
-
Witte JS, Gauderman WJ, Thomas DC (1999) Asymptotic bias and efficiency in case-control studies of candidate genes and gene-environment interactions: Basic family designs. Am J Epidemiol 148:693-705
-
(1999)
Am J Epidemiol
, vol.148
, pp. 693-705
-
-
Witte, J.S.1
Gauderman, W.J.2
Thomas, D.C.3
-
80
-
-
2642527702
-
Many amino acid substitution variants identified in DNA repair genes during human population screenings are predicted to impact protein function
-
Xi T, Jones IM, Mohrenweiser HW (2004) Many amino acid substitution variants identified in DNA repair genes during human population screenings are predicted to impact protein function. Genomics 83:970-979
-
(2004)
Genomics
, vol.83
, pp. 970-979
-
-
Xi, T.1
Jones, I.M.2
Mohrenweiser, H.W.3
-
81
-
-
0036284203
-
Testing association of statistically inferred haplotypes with discrete and continuous traits in samples of unrelated individuals
-
Zaykin DV, Westfall PH, Young SS, Karnoub MA, Wagner MJ, Ehm MG (2002) Testing association of statistically inferred haplotypes with discrete and continuous traits in samples of unrelated individuals. Hum Hered 53:79-91
-
(2002)
Hum Hered
, vol.53
, pp. 79-91
-
-
Zaykin, D.V.1
Westfall, P.H.2
Young, S.S.3
Karnoub, M.A.4
Wagner, M.J.5
Ehm, M.G.6
-
82
-
-
1542405868
-
An evolutionary perspective on single-nucleotide polymorphism screening in molecular cancer epidemiology
-
Zhu Y, Spitz MR, Amos CI, Lin J, Schabath MB, Wu X (2004) An evolutionary perspective on single-nucleotide polymorphism screening in molecular cancer epidemiology. Cancer Res 64:2251-2257
-
(2004)
Cancer Res
, vol.64
, pp. 2251-2257
-
-
Zhu, Y.1
Spitz, M.R.2
Amos, C.I.3
Lin, J.4
Schabath, M.B.5
Wu, X.6
|