Ultraconserved elements in the human genome

Science

Volumn 304, Issue 5675, 2004, Pages 1321-1325

  Bejerano, Gill ^a   Pheasant, Michael ^c   Makunin, Igor ^c   Stephen, Stuart ^c   Kent, W James ^a   Mattick, John S ^c   Haussler, David ^b  

^a University of California Santa Cruz   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

GENES; HUMAN ENGINEERING; PROTEINS; RNA;

HUMAN GENOMES; ONTOGENY;

GENETIC ENGINEERING;

PROTEIN;

GENOME;

ARTICLE; BASE PAIRING; CHICKEN; DEVELOPMENT; DOG; EVOLUTION; EXON; FISH; GENE LOCATION; GENETIC CONSERVATION; HUMAN; HUMAN GENOME; INTRON; MAMMAL; MOUSE; NONHUMAN; ONTOGENY; PRIORITY JOURNAL; RAT; RNA PROCESSING; SEQUENCE HOMOLOGY; TRANSCRIPTION REGULATION; VERTEBRATE;

ALTERNATIVE SPLICING; ANIMALS; BASE SEQUENCE; CHICKENS; COMPUTATIONAL BIOLOGY; CONSERVED SEQUENCE; DNA, INTERGENIC; DOGS; EVOLUTION, MOLECULAR; EXONS; GENE EXPRESSION REGULATION; GENES; GENOME; GENOME, HUMAN; HUMANS; INTRONS; MICE; MOLECULAR SEQUENCE DATA; MUTATION; NUCLEIC ACID CONFORMATION; RATS; RNA; TAKIFUGU;

CANIS FAMILIARIS; GALLUS GALLUS; MAMMALIA; VERTEBRATA;

EID: 2542542256     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1098119     Document Type: Article

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39. We thank the Genome Sequencing Consortia for the human, mouse, rat, dog, chicken, and other genome sequences we used in this analysis; W. Miller, M. Diekhans, A. Hinrichs, K. Rosenbloom, D. Thomas, and the members of the University of California Santa Cruz (UCSC) browser team for providing the genome alignments and other tracks of genome annotation available on the UCSC genome browser; M. Blanchette, S. Salama, T. Lowe, M. Ares, K. Pollard, and B. Cohen for helpful discussions; A. Siepel for the neutral substitution rate analysis involving chicken and chimp; K. Roskin for the calculation of the percent identity in ancestral repeat sites for 1-Mb windows; and S. Walton for help in preparing the manuscript. G.B., W.J.K., and D.H. were supported by National Human Genome Research Institute grant 1P41HG02371 and National Cancer Institute contract 22XS013A, and D.H. was additionally supported by the Howard Hughes Medical Institute. S.S., M.P., I.M, and J.S.M. were supported by the Australian Research Council and the Queensland State Government.