Iron-binding drugs targeted to lysosomes: A potential strategy to treat inflammatory lung disorders

Expert Opinion on Investigational Drugs

Volumn 14, Issue 8, 2005, Pages 997-1008

  Persson, H Lennart ^a   Richardson, Des R ^b  

^a LINKÖPING UNIVERSITY   (Sweden)

^b CHILDREN S CANCER INSTITUTE AUSTRALIA FOR MEDICAL RESEARCH   (Australia)

Author keywords

Apoptosis; Desferritoxamine; Lipoic acid; Oxidative stress; Silica; WR 1065

Indexed keywords

2 (3 AMINOPROPYLAMINO)ETHANETHIOL; AMIFOSTINE; APOFERRITIN; DEFEROXAMINE; HYDROGEN PEROXIDE; IRON; IRON CHELATING AGENT; SILICON DIOXIDE; THIOCTIC ACID;

APOPTOSIS; CELL CULTURE; CELL PROTECTION; DRUG MECHANISM; DRUG STRUCTURE; DRUG TARGETING; EPITHELIUM CELL; HUMAN; IN VITRO STUDY; IN VIVO STUDY; IONIZING RADIATION; IRON CHELATION; IRON METABOLISM; LYSOSOME; MACROPHAGE; NONHUMAN; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PNEUMONIA; REGULATORY MECHANISM; RESPIRATORY EPITHELIUM; REVIEW; SIDE EFFECT;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; DRUG DELIVERY SYSTEMS; DRUGS, INVESTIGATIONAL; HUMANS; IRON; IRON CHELATING AGENTS; LUNG DISEASES; LYSOSOMES;

EID: 23644436374     PISSN: 13543784     EISSN: None     Source Type: Journal    
DOI: 10.1517/13543784.14.8.997     Document Type: Review

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