Amifostine induces anaerobic metabolism and hypoxia-inducible factor 1α

Cancer Chemotherapy and Pharmacology

Volumn 53, Issue 1, 2004, Pages 8-14

  Koukourakis, Michael I ^a   Giatromanolaki, Alexandra ^a   Chong, Wen ^b   Simopoulos, Costantinos ^a   Polychronidis, Alexandros ^a   Sivridis, Efthimios ^a   Harris, Adrian L ^b  

^a DEMOCRITUS UNIVERSITY OF THRACE   (Greece)

^b JOHN RADCLIFFE HOSPITAL   (United Kingdom)

Author keywords

Amifostine; Glycolysis; HIf1 ; Hypoxia

Indexed keywords

2 (3 AMINOPROPYLAMINO)ETHANETHIOL; ALKALINE PHOSPHATASE; AMIFOSTINE; GLUCOSE; HEMOGLOBIN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; OXYGEN; TRANSCRIPTION FACTOR;

ANAEROBIC METABOLISM; ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BREAST CARCINOMA; BREAST TUMOR; CANCER RESISTANCE; CELL HYPOXIA; CELL LINE; CELL PROTECTION; CLINICAL ARTICLE; CLINICAL TRIAL; DEPHOSPHORYLATION; ENZYME ACTIVITY; GLUCOSE BLOOD LEVEL; GLYCOLYSIS; HUMAN; HUMAN CELL; HYDROLYSIS; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; MALE; NONHUMAN; OXYGEN BLOOD LEVEL; OXYGEN SATURATION; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN DETERMINATION; RADIOSENSITIVITY; RAT; RAT STRAIN; TISSUE METABOLISM; UPREGULATION; WESTERN BLOTTING;

AMIFOSTINE; ANIMALS; BLOOD GLUCOSE; BLOTTING, WESTERN; BREAST NEOPLASMS; CELL HYPOXIA; CELL LINE, TUMOR; CYTOPROTECTION; FEMALE; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; IMMUNOHISTOCHEMISTRY; INFUSIONS, INTRAVENOUS; KIDNEY; LUNG; MALE; RADIATION DOSAGE; RADIATION-PROTECTIVE AGENTS; RATS; RATS, WISTAR; TRANSCRIPTION FACTORS; UP-REGULATION;

EID: 0742269445     PISSN: 03445704     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00280-003-0691-z     Document Type: Article

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