-
1
-
-
0034568428
-
"Chemoprotective and radioprotective effects of amifostine: Un update of clinical trials"
-
Capizzi, R.L. and Oster, W. (2000) "Chemoprotective and radioprotective effects of amifostine: Un update of clinical trials", Int. J. Hematol. 72, 425-435.
-
(2000)
Int. J. Hematol.
, vol.72
, pp. 425-435
-
-
Capizzi, R.L.1
Oster, W.2
-
2
-
-
0035023506
-
"Amifostine: Chemotherapeutic and radiotherapeutic protective effects"
-
Santini, V. (2001) "Amifostine: Chemotherapeutic and radiotherapeutic protective effects", Exp. Opin. Pharmacother. 2, 479-489.
-
(2001)
Exp. Opin. Pharmacother.
, vol.2
, pp. 479-489
-
-
Santini, V.1
-
3
-
-
0029129978
-
"Degradation of 2-(3-aminopropylamino)- ethanethiol (WR-1065) by Cu-dependent amine oxidases and influence on glutathione status of Chinese hamster ovary cells"
-
Meier, T. and Issels, R.D. (1995) "Degradation of 2-(3-aminopropylamino)- ethanethiol (WR-1065) by Cu-dependent amine oxidases and influence on glutathione status of Chinese hamster ovary cells", Biochem. Pharmacol. 50, 489-496.
-
(1995)
Biochem. Pharmacol.
, vol.50
, pp. 489-496
-
-
Meier, T.1
Issels, R.D.2
-
4
-
-
0028127149
-
"Metabolic pathways of WR-2721 (Ethyol, amifostine) in the balb/c mouse"
-
Shaw, L.M., Bonner, H.S. and Brown, D.Q. (1994) "Metabolic pathways of WR-2721 (Ethyol, amifostine) in the balb/c mouse", Drug Metab. Dispos. 22, 895-902.
-
(1994)
Drug Metab. Dispos.
, vol.22
, pp. 895-902
-
-
Shaw, L.M.1
Bonner, H.S.2
Brown, D.Q.3
-
5
-
-
0034520732
-
"Amifostine: Mechanisms of action underlying cytoprotection and chemoprevention"
-
Grdina, D.J., Kataoka, Y. and Murley, J.S. (2000) "Amifostine: Mechanisms of action underlying cytoprotection and chemoprevention", Drug Metabol. Drug. Interact. 16, 237-279.
-
(2000)
Drug Metabol. Drug. Interact.
, vol.16
, pp. 237-279
-
-
Grdina, D.J.1
Kataoka, Y.2
Murley, J.S.3
-
6
-
-
0031735122
-
"Radioprotectants: Pharmacology and clinical applications of amifostine"
-
Dorr, R.T. (1998) "Radioprotectants: Pharmacology and clinical applications of amifostine", Semin. Radiat. Oncol. 8, 10-13.
-
(1998)
Semin. Radiat. Oncol.
, vol.8
, pp. 10-13
-
-
Dorr, R.T.1
-
7
-
-
0033762373
-
"Amifostine: A tonic or toxin to myeloid progenitors"
-
List, A.F. and Gerner, E.W. (2000) "Amifostine: A tonic or toxin to myeloid progenitors", Leuk. Res. 24, 1009-1011.
-
(2000)
Leuk. Res.
, vol.24
, pp. 1009-1011
-
-
List, A.F.1
Gerner, E.W.2
-
8
-
-
0036094003
-
"Selective exclusion by the polyamine transporter as a mechanism for differential radioprotection of amifostine derivatives"
-
Quinones, H.I., List, A.F. and Gerner, E.W. (2002) "Selective exclusion by the polyamine transporter as a mechanism for differential radioprotection of amifostine derivatives", Clin. Cancer Res. 8, 1295-1300.
-
(2002)
Clin. Cancer Res.
, vol.8
, pp. 1295-1300
-
-
Quinones, H.I.1
List, A.F.2
Gerner, E.W.3
-
9
-
-
0037050003
-
"Inhibition of spotaneous metastases formation by amifostine"
-
Grdina, D.J., Kataoka, Y., Murley, J.S., Hunter, N., Weichselbaum, R.R. and Milas, L. (2002) "Inhibition of spotaneous metastases formation by amifostine", Int. J. Cancer 97, 135-141.
-
(2002)
Int. J. Cancer
, vol.97
, pp. 135-141
-
-
Grdina, D.J.1
Kataoka, Y.2
Murley, J.S.3
Hunter, N.4
Weichselbaum, R.R.5
Milas, L.6
-
10
-
-
0036765925
-
"Amifostine protects blood vessels from the effects of ionizing radiation"
-
Giannopoulou, E., Katsoris, P., Parthymou, A., Kardamakis, D. and Papadimitriou, E. (2002) "Amifostine protects blood vessels from the effects of ionizing radiation", Anticancer Res. 22, 2821-2826.
-
(2002)
Anticancer Res.
, vol.22
, pp. 2821-2826
-
-
Giannopoulou, E.1
Katsoris, P.2
Parthymou, A.3
Kardamakis, D.4
Papadimitriou, E.5
-
11
-
-
0037221332
-
"Inhibition of angiogenesis at endothelial cell level"
-
Jekunen, A. and Kairemo, K. (2003) "Inhibition of angiogenesis at endothelial cell level", Microsc. Res. Tech. 60, 85-97.
-
(2003)
Microsc. Res. Tech.
, vol.60
, pp. 85-97
-
-
Jekunen, A.1
Kairemo, K.2
-
12
-
-
0037308079
-
"Amifostine inhibits angiogenesis in vivo"
-
Giannopoulou, E., Katsoris, P., Kardamakis, D. and Papadimitriou, E. (2003) "Amifostine inhibits angiogenesis in vivo", J. Pharmacol. Exp. Ther. 304, 729-737.
-
(2003)
J. Pharmacol. Exp. Ther.
, vol.304
, pp. 729-737
-
-
Giannopoulou, E.1
Katsoris, P.2
Kardamakis, D.3
Papadimitriou, E.4
-
13
-
-
0034708220
-
"The cytoprotective aminothiol WR1065 activates p21 waf-1 and down regulates cell cycle progression through a p53-dependent pathway"
-
North, S., El-Ghissassi, F., Pluquet, O., Verhaegh, G. and Hainaut, P. (2000) "The cytoprotective aminothiol WR1065 activates p21 waf-1 and down regulates cell cycle progression through a p53-dependent pathway", Oncogene 19, 1206-1214.
-
(2000)
Oncogene
, vol.19
, pp. 1206-1214
-
-
North, S.1
El-Ghissassi, F.2
Pluquet, O.3
Verhaegh, G.4
Hainaut, P.5
-
14
-
-
0031410502
-
"Repression of c-myc gene expression by the thiol and disulfide forms of the cytoprotector amifostine"
-
Liu, S.C., Murley, J.S., Woloschak, G. and Grdina, D.J. (1997) "Repression of c-myc gene expression by the thiol and disulfide forms of the cytoprotector amifostine", Carcinogenesis 18, 2457-2459.
-
(1997)
Carcinogenesis
, vol.18
, pp. 2457-2459
-
-
Liu, S.C.1
Murley, J.S.2
Woloschak, G.3
Grdina, D.J.4
-
15
-
-
0031473153
-
"WR-1065, an active metabolite of the cytoprotector amifostine, affects phosphorylation of topoisomerase IIá leading to changes in enzyme activity and cell cycle progression in CHO AAS cells"
-
Murley, J.S., Constantinou, A., Kamanth, N.S. and Grdina, D.J. (1997) "WR-1065, an active metabolite of the cytoprotector amifostine, affects phosphorylation of topoisomerase IIá leading to changes in enzyme activity and cell cycle progression in CHO AAS cells", Cell Prolif. 30, 283-294.
-
(1997)
Cell Prolif.
, vol.30
, pp. 283-294
-
-
Murley, J.S.1
Constantinou, A.2
Kamanth, N.S.3
Grdina, D.J.4
-
16
-
-
0032721492
-
"Radioprotection of human endothelial cells with amifostine"
-
Andreopoulos, D., Schleicher, U.M., Cortarelo, C.L., Hand, S. and Ammon, J. (1999) "Radioprotection of human endothelial cells with amifostine", Strahlenther. Onkol. 175, 34-36.
-
(1999)
Strahlenther. Onkol.
, vol.175
, pp. 34-36
-
-
Andreopoulos, D.1
Schleicher, U.M.2
Cortarelo, C.L.3
Hand, S.4
Ammon, J.5
-
17
-
-
0030024906
-
"WR-1065 and radioprotection of vascular endothelial cells. I. Cell proliferation, DNA synthesis and damage"
-
Rubin, D.B., Drab, E.A., Kang, H.J., Baumann, F.E. and Blazek, E.R. (1996) "WR-1065 and radioprotection of vascular endothelial cells. I. Cell proliferation, DNA synthesis and damage", Radiat. Res. 145, 210-216.
-
(1996)
Radiat. Res.
, vol.145
, pp. 210-216
-
-
Rubin, D.B.1
Drab, E.A.2
Kang, H.J.3
Baumann, F.E.4
Blazek, E.R.5
-
18
-
-
0030067513
-
"WR-1065 and radioprotection of vascular endothelial cells. II. Morphology"
-
Mooteri, S.N., Podolski, J.L., Drab, E.A., Saclarides, T.J., Onoda, J.M., Kantak, S.S. and Rubin, D.B. (1996) "WR-1065 and radioprotection of vascular endothelial cells. II. Morphology", Radiat. Res. 145, 217-224.
-
(1996)
Radiat. Res.
, vol.145
, pp. 217-224
-
-
Mooteri, S.N.1
Podolski, J.L.2
Drab, E.A.3
Saclarides, T.J.4
Onoda, J.M.5
Kantak, S.S.6
Rubin, D.B.7
-
19
-
-
0037466841
-
"Different inhibitors of plasmin differentially affect angiostatin production and angiogenesis"
-
Hatziapostolou, M., Katsoris, P. and Papadimitriou, E. (2003) "Different inhibitors of plasmin differentially affect angiostatin production and angiogenesis", Eur. J. Pharmacol. 460, 1-8.
-
(2003)
Eur. J. Pharmacol.
, vol.460
, pp. 1-8
-
-
Hatziapostolou, M.1
Katsoris, P.2
Papadimitriou, E.3
-
20
-
-
0035545941
-
"X-rays modulate extracellular matrix in vivo"
-
Giannopoulou, E., Katsoris, P., Hatziapostolou, M., Kardamakis, D., Kotsaki, E., Polytarchou, C., Parthymou, A., Papaioannou, S. and Papadimitriou, E. (2001) "X-rays modulate extracellular matrix in vivo", Int. J. Cancer 94, 690-698.
-
(2001)
Int. J. Cancer
, vol.94
, pp. 690-698
-
-
Giannopoulou, E.1
Katsoris, P.2
Hatziapostolou, M.3
Kardamakis, D.4
Kotsaki, E.5
Polytarchou, C.6
Parthymou, A.7
Papaioannou, S.8
Papadimitriou, E.9
-
21
-
-
0037092052
-
"Nitration of cytoskeletal proteins in the chicken embryo chorioallantoic membrane"
-
Giannopoulou, E., Katsoris, P., Polytarchou, C. and Papadimitriou, E. (2002) "Nitration of cytoskeletal proteins in the chicken embryo chorioallantoic membrane", Arch. Biochem. Biophys. 400, 188-198.
-
(2002)
Arch. Biochem. Biophys.
, vol.400
, pp. 188-198
-
-
Giannopoulou, E.1
Katsoris, P.2
Polytarchou, C.3
Papadimitriou, E.4
-
22
-
-
0036910386
-
"The role of hydrogen peroxide in endothelial proliferative responses"
-
Stone, J.R. and Collins, T. (2002) "The role of hydrogen peroxide in endothelial proliferative responses", Endothelium 9, 231-238.
-
(2002)
Endothelium
, vol.9
, pp. 231-238
-
-
Stone, J.R.1
Collins, T.2
-
23
-
-
0034871558
-
"Mechanisms for the cytotoxicity of cysteamine"
-
Jeither, T.M. and Lawrence, D.A. (2001) "Mechanisms for the cytotoxicity of cysteamine", Toxicol. Sci. 62, 57-64.
-
(2001)
Toxicol. Sci.
, vol.62
, pp. 57-64
-
-
Jeither, T.M.1
Lawrence, D.A.2
-
24
-
-
0027930460
-
"Mechanisms for the oxygen radical-mediated toxicity of various thiol-containing compounds in cultured mammalian cells"
-
Held, K.D. and Biaglow, J.E. (1994) "Mechanisms for the oxygen radical-mediated toxicity of various thiol-containing compounds in cultured mammalian cells", Radiat. Res. 139, 15-23.
-
(1994)
Radiat. Res.
, vol.139
, pp. 15-23
-
-
Held, K.D.1
Biaglow, J.E.2
-
25
-
-
0035099627
-
"Polyamines in cell growth and cell death: Molecular mechanisms and therapeutics application"
-
Thomas, T. and Thomas, T.J. (2001) "Polyamines in cell growth and cell death: molecular mechanisms and therapeutics application", Cell Mol. Life Sci. 58, 244-258.
-
(2001)
Cell Mol. Life Sci.
, vol.58
, pp. 244-258
-
-
Thomas, T.1
Thomas, T.J.2
-
26
-
-
0032036349
-
"Hydrogen peroxide activates extracellular signal-regulated kinase via ptotein kinase C, Raf-1 and MEK1"
-
Abe, M., Kartha, S., Karpova, A., Li, J., Liu, P., Kuo, W. and Hershenson, M. (1998) "Hydrogen peroxide activates extracellular signal-regulated kinase via ptotein kinase C, Raf-1 and MEK1", Am. J. Respir. Cell Mol. Biol. 18, 562-569.
-
(1998)
Am. J. Respir. Cell Mol. Biol.
, vol.18
, pp. 562-569
-
-
Abe, M.1
Kartha, S.2
Karpova, A.3
Li, J.4
Liu, P.5
Kuo, W.6
Hershenson, M.7
-
27
-
-
0032545526
-
"Stimulation of in vitro angiogenesis by hydrogen peroxide and the relation with ETS-1 in endothelial cells"
-
Yasuda, M., Ohzeki, Y., Shimizu, S., Naito, S., Ohtsuru, A., Yamamoto, T. and Kuroiwa, Y. (1999) "Stimulation of in vitro angiogenesis by hydrogen peroxide and the relation with ETS-1 in endothelial cells", Life Sci. 64, 249-258.
-
(1999)
Life Sci.
, vol.64
, pp. 249-258
-
-
Yasuda, M.1
Ohzeki, Y.2
Shimizu, S.3
Naito, S.4
Ohtsuru, A.5
Yamamoto, T.6
Kuroiwa, Y.7
-
28
-
-
0036607064
-
"Crosstalk between cAMP and MAP kinase signaling in the regulation of cell proliferation"
-
Stork, P.J. and Schmitt, J.M. (2002) "Crosstalk between cAMP and MAP kinase signaling in the regulation of cell proliferation", Trends Cell Biol. 12, 258-266.
-
(2002)
Trends Cell Biol.
, vol.12
, pp. 258-266
-
-
Stork, P.J.1
Schmitt, J.M.2
-
29
-
-
0029828566
-
"Cyclic AMP inhibits activation of mitogen-activated protein kinase and cell proliferation in response to growth factors in cultured rat cortical astrocytes"
-
Kurino, M., Fukunaga, K., Ushio, Y. and Miyamoto, E. (1996) "Cyclic AMP inhibits activation of mitogen-activated protein kinase and cell proliferation in response to growth factors in cultured rat cortical astrocytes", J. Neurochem. 67, 2246-2255.
-
(1996)
J. Neurochem.
, vol.67
, pp. 2246-2255
-
-
Kurino, M.1
Fukunaga, K.2
Ushio, Y.3
Miyamoto, E.4
-
30
-
-
0032532296
-
"Mammalian cell polyamine homeostasis is altered by the radioprotector WR-1065"
-
Mitcell, J., Rupert, J., Leyser, A. and Judd, G. (1998) "Mammalian cell polyamine homeostasis is altered by the radioprotector WR-1065", Biochem. J. 335, 329-334.
-
(1998)
Biochem. J.
, vol.335
, pp. 329-334
-
-
Mitcell, J.1
Rupert, J.2
Leyser, A.3
Judd, G.4
-
31
-
-
0037021412
-
"Arginine metabolic pathways involved in the modulation of tumor-induced angiogenesis by macrophages"
-
Davel, L.E., Jasnis, M.A., Torre, E., Gotoh, T., Diament, M., Magenta, G., Lustig, S.E. and Sales, M.E. (2002) "Arginine metabolic pathways involved in the modulation of tumor-induced angiogenesis by macrophages", FEBS Lett. 532, 216-220.
-
(2002)
FEBS Lett.
, vol.532
, pp. 216-220
-
-
Davel, L.E.1
Jasnis, M.A.2
Torre, E.3
Gotoh, T.4
Diament, M.5
Magenta, G.6
Lustig, S.E.7
Sales, M.E.8
-
32
-
-
0028998931
-
"Vascular endothelial cell proliferation: Regulation of cellular polyamines"
-
Morrison, R.F. and Seidel, E.R. (1995) "Vascular endothelial cell proliferation: Regulation of cellular polyamines", Cardiovasc. Res. 29, 841-847.
-
(1995)
Cardiovasc. Res.
, vol.29
, pp. 841-847
-
-
Morrison, R.F.1
Seidel, E.R.2
-
33
-
-
0034807808
-
"Polyamine metabolism revisited"
-
Urdiales, J.L., Medina, M.A. and Sanchez-Jimenez, F. (2001) "Polyamine metabolism revisited", Eur. J. Gastroenterol. Hepatol. 13, 1015-1019.
-
(2001)
Eur. J. Gastroenterol. Hepatol.
, vol.13
, pp. 1015-1019
-
-
Urdiales, J.L.1
Medina, M.A.2
Sanchez-Jimenez, F.3
-
35
-
-
0037317540
-
"Inhibition of LPS-induced nitric oxide production in RAW cells by radioprotective thiols"
-
Kumar, K.S., Singh, V.K., Jackson, W. and Seed, T.M. (2003) "Inhibition of LPS-induced nitric oxide production in RAW cells by radioprotective thiols", Exp. Mol. Pathol. 74, 68-73.
-
(2003)
Exp. Mol. Pathol.
, vol.74
, pp. 68-73
-
-
Kumar, K.S.1
Singh, V.K.2
Jackson, W.3
Seed, T.M.4
-
36
-
-
0035874637
-
"Activation of NFêB and MnSOD gene expression by free radical scavengers in human microvascular endothelial cells"
-
Murley, J.S., Kataoka, Y., Hallahan, D.E., Roberts, J.C. and Grdina, D.J. (2001) "Activation of NFêB and MnSOD gene expression by free radical scavengers in human microvascular endothelial cells", Free Radic. Biol. Med. 30, 1426-1439.
-
(2001)
Free Radic. Biol. Med.
, vol.30
, pp. 1426-1439
-
-
Murley, J.S.1
Kataoka, Y.2
Hallahan, D.E.3
Roberts, J.C.4
Grdina, D.J.5
-
37
-
-
0034693229
-
"Tyrosine nitration peroxynitrite formed from nitric oxide and superoxide generated by xanthine oxidase"
-
Sawa, T., Akaike, T. and Maeda, H. (2000) "Tyrosine nitration peroxynitrite formed from nitric oxide and superoxide generated by xanthine oxidase", J. Biol. Chem. 275, 32467-32474.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 32467-32474
-
-
Sawa, T.1
Akaike, T.2
Maeda, H.3
|