-
1
-
-
0028946766
-
Accumulation of wild-type p53 protein upon gamma-irradiation induces a G2 arrest-dependent immunoglobulin kappa light chain gene expression
-
Aloni-Grinstein R, Schwartz D, Rotter V. 1995. Accumulation of wild-type p53 protein upon gamma-irradiation induces a G2 arrest-dependent immunoglobulin kappa light chain gene expression. EMBO J 14:1392-1401.
-
(1995)
EMBO J
, vol.14
, pp. 1392-1401
-
-
Aloni-Grinstein, R.1
Schwartz, D.2
Rotter, V.3
-
2
-
-
0035365180
-
Decrease in drug accumulation and in tumour aggressiveness marker expression in a fenretinide-induced resistant ovarian tumour cell line
-
Appierto V, Cavadini E, Pergolizzi R, Cleris L, Lotan R, Canevari S, Formelli F. 2001. Decrease in drug accumulation and in tumour aggressiveness marker expression in a fenretinide-induced resistant ovarian tumour cell line. Br J Cancer 84:1528-1534.
-
(2001)
Br J Cancer
, vol.84
, pp. 1528-1534
-
-
Appierto, V.1
Cavadini, E.2
Pergolizzi, R.3
Cleris, L.4
Lotan, R.5
Canevari, S.6
Formelli, F.7
-
3
-
-
0032910169
-
Apoptosis control by death and decoy receptors
-
Ashkenazi A, Dixit VM. 1999. Apoptosis control by death and decoy receptors. Curr Opin Cell Biol 11:255-260.
-
(1999)
Curr Opin Cell Biol
, vol.11
, pp. 255-260
-
-
Ashkenazi, A.1
Dixit, V.M.2
-
4
-
-
0034647694
-
p38 mitogen-activated protein kinase regulates a novel, caspase-independent pathway for the mitochondrial cytochrome c release in ultraviolet B radiation-induced apoptosis
-
Assefa Z, Vantieghem A, Garmyn M, Declercq W, Vandenabeele P, Vandenheede JR, Bouillon R, Merlevede W, Agostinis P. 2000. p38 mitogen-activated protein kinase regulates a novel, caspase-independent pathway for the mitochondrial cytochrome c release in ultraviolet B radiation-induced apoptosis. J Biol Chem 275:21416-21421.
-
(2000)
J Biol Chem
, vol.275
, pp. 21416-21421
-
-
Assefa, Z.1
Vantieghem, A.2
Garmyn, M.3
Declercq, W.4
Vandenabeele, P.5
Vandenheede, J.R.6
Bouillon, R.7
Merlevede, W.8
Agostinis, P.9
-
5
-
-
0029111404
-
Increased activity of p53 in senescing fibroblasts
-
Atadja P, Wong H, Garkavtsev I, Veillette C, Riabowol K. 1995. Increased activity of p53 in senescing fibroblasts. Proc Natl Acad Sci USA 92:8348-8352.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 8348-8352
-
-
Atadja, P.1
Wong, H.2
Garkavtsev, I.3
Veillette, C.4
Riabowol, K.5
-
6
-
-
0030013337
-
Transcriptional activation by p53, but not induction of the p21 gene, is essential for oncogene-mediated apoptosis
-
Attardi LD, Lowe SW, Brugarolas J, Jacks T. 1996. Transcriptional activation by p53, but not induction of the p21 gene, is essential for oncogene-mediated apoptosis. EMBO J 15:3693-3701.
-
(1996)
EMBO J
, vol.15
, pp. 3693-3701
-
-
Attardi, L.D.1
Lowe, S.W.2
Brugarolas, J.3
Jacks, T.4
-
7
-
-
0346402819
-
Tumor Necrosis Factor-{alpha} activation of the Jun NH{sub2}-terminal Kinase (JNK) pathway in human neutrophils: Integrin involvement in a pathway leading from cytoplasmic tyrosine kinases to apoptosis
-
Avdi NJ, Nick JA, Whitlock BB, Billstrom MA, Henson PM, Johnson GL, Worthen GS. 2000. Tumor Necrosis Factor-{alpha} activation of the Jun NH{sub2}-terminal Kinase (JNK) pathway in human neutrophils: Integrin involvement in a pathway leading from cytoplasmic tyrosine kinases to apoptosis. J Biol Chem 25:25.
-
(2000)
J Biol Chem
, vol.25
, pp. 25
-
-
Avdi, N.J.1
Nick, J.A.2
Whitlock, B.B.3
Billstrom, M.A.4
Henson, P.M.5
Johnson, G.L.6
Worthen, G.S.7
-
8
-
-
0032411879
-
Stress signals for apoptosis: Ceramide and c-Jun kinase
-
Basu S, Kolesnick R. 1998. Stress signals for apoptosis: Ceramide and c-Jun kinase. Oncogene 17:3277-3285.
-
(1998)
Oncogene
, vol.17
, pp. 3277-3285
-
-
Basu, S.1
Kolesnick, R.2
-
9
-
-
0033490947
-
Apoptosis and apoptosis-related proteins in the epithelium of human ovarian tumors: Immunohistochemical and morphometric studies
-
Ben-Hur H, Gurevich P, Huszar M, Ben-Arie A, Berman V, Tendler Y, Tchanishev R, Zinder O, Mor G, Zaltsman Y, Kohen F, Zusman I. 1999. Apoptosis and apoptosis-related proteins in the epithelium of human ovarian tumors: Immunohistochemical and morphometric studies. Eur J Gynaecol Oncol 20:249-253.
-
(1999)
Eur J Gynaecol Oncol
, vol.20
, pp. 249-253
-
-
Ben-Hur, H.1
Gurevich, P.2
Huszar, M.3
Ben-Arie, A.4
Berman, V.5
Tendler, Y.6
Tchanishev, R.7
Zinder, O.8
Mor, G.9
Zaltsman, Y.10
Kohen, F.11
Zusman, I.12
-
10
-
-
0037093812
-
Fas (CD95/APO-1) and Fas ligand expression in normal pancreas and pancreatic tumors. Implications for immune privilege and immune escape
-
Bernstorff WV, Glickman JN, Odze RD, Farraye FA, Joo HG, Goedegebuure PS, Eberlein TJ. 2002. Fas (CD95/APO-1) and Fas ligand expression in normal pancreas and pancreatic tumors. Implications for immune privilege and immune escape. Cancer 94:2552-2560.
-
(2002)
Cancer
, vol.94
, pp. 2552-2560
-
-
Bernstorff, W.V.1
Glickman, J.N.2
Odze, R.D.3
Farraye, F.A.4
Joo, H.G.5
Goedegebuure, P.S.6
Eberlein, T.J.7
-
11
-
-
0037179867
-
MEKK1-induced apoptosis requires TRAIL death receptor activation and is inhibited by AKT/PKB through inhibition of MEKK1 cleavage
-
Bild AH, Mendoza FJ, Gibson EM, Huang M, Villanueva J, Garrington TP, Jove R, Johnson GL, Gibson SB. 2002. MEKK1-induced apoptosis requires TRAIL death receptor activation and is inhibited by AKT/PKB through inhibition of MEKK1 cleavage. Oncogene 21:6649-6656.
-
(2002)
Oncogene
, vol.21
, pp. 6649-6656
-
-
Bild, A.H.1
Mendoza, F.J.2
Gibson, E.M.3
Huang, M.4
Villanueva, J.5
Garrington, T.P.6
Jove, R.7
Johnson, G.L.8
Gibson, S.B.9
-
12
-
-
8044257704
-
A metalloproteinase disintegrin that releases tumour-necrosis factor-alpha from cells
-
Black RA, Rauch CT, Kozlosky CJ, Peschon JJ, Slack JL, Wolfson MF, Castner BJ, Stocking KL, Reddy P, Srinivasan S, Nelson N, Boiani N, Schooley KA, Gerhart M, Davis R, Fitzner JN, Johnson RS, Paxton RJ, March CJ, Cerretti DP. 1997. A metalloproteinase disintegrin that releases tumour-necrosis factor-alpha from cells. Nature 385:729-733.
-
(1997)
Nature
, vol.385
, pp. 729-733
-
-
Black, R.A.1
Rauch, C.T.2
Kozlosky, C.J.3
Peschon, J.J.4
Slack, J.L.5
Wolfson, M.F.6
Castner, B.J.7
Stocking, K.L.8
Reddy, P.9
Srinivasan, S.10
Nelson, N.11
Boiani, N.12
Schooley, K.A.13
Gerhart, M.14
Davis, R.15
Fitzner, J.N.16
Johnson, R.S.17
Paxton, R.J.18
March, C.J.19
Cerretti, D.P.20
more..
-
13
-
-
0033580901
-
Caspases induce cytochrome c release from mitochondria by activating cytosolic factors
-
Bossy-Wetzel E, Green DR. 1999. Caspases induce cytochrome c release from mitochondria by activating cytosolic factors. J Biol Chem 274:17484-17490.
-
(1999)
J Biol Chem
, vol.274
, pp. 17484-17490
-
-
Bossy-Wetzel, E.1
Green, D.R.2
-
14
-
-
0031873198
-
Fas/CD95/Apo-I activates the acidic sphingomyelinase via caspases
-
Brenner B, Ferlinz K, Grassme H, Weller M, Koppenhoefer U, Dichgans J, Sandhoff K, Lang F, Gulbins E. 1998. Fas/CD95/Apo-I activates the acidic sphingomyelinase via caspases. Cell Death Differ 5:29-37.
-
(1998)
Cell Death Differ
, vol.5
, pp. 29-37
-
-
Brenner, B.1
Ferlinz, K.2
Grassme, H.3
Weller, M.4
Koppenhoefer, U.5
Dichgans, J.6
Sandhoff, K.7
Lang, F.8
Gulbins, E.9
-
15
-
-
0028070989
-
p53-dependent apoptosis in the absence of transcriptional activation of p53-target genes
-
Caelles C, Helmberg A, Karin M. 1994. p53-dependent apoptosis in the absence of transcriptional activation of p53-target genes. Nature 370:220-223.
-
(1994)
Nature
, vol.370
, pp. 220-223
-
-
Caelles, C.1
Helmberg, A.2
Karin, M.3
-
16
-
-
0036012750
-
Cloning and characterization of rat caspase-9: Implications for a role in mediating caspase-3 activation and hippocampal cell death after transient cerebral ischemia
-
Cao G, Luo Y, Nagayama T, Pei W, Stetler RA, Graham SH, Chen J. 2002. Cloning and characterization of rat caspase-9: Implications for a role in mediating caspase-3 activation and hippocampal cell death after transient cerebral ischemia. J Cereb Blood Flow Metab 22:534-546.
-
(2002)
J Cereb Blood Flow Metab
, vol.22
, pp. 534-546
-
-
Cao, G.1
Luo, Y.2
Nagayama, T.3
Pei, W.4
Stetler, R.A.5
Graham, S.H.6
Chen, J.7
-
17
-
-
0031040486
-
Matrix metalloproteinases, tumor necrosis factor and multiple sclerosis: An overview
-
Chandler S, Miller KM, Clements JM, Lury J, Corkill D, Anthony DC, Adams SE, Gearing AJ. 1997. Matrix metalloproteinases, tumor necrosis factor and multiple sclerosis: An overview. J Neuroimmunol 72:155-161.
-
(1997)
J Neuroimmunol
, vol.72
, pp. 155-161
-
-
Chandler, S.1
Miller, K.M.2
Clements, J.M.3
Lury, J.4
Corkill, D.5
Anthony, D.C.6
Adams, S.E.7
Gearing, A.J.8
-
18
-
-
0031918223
-
BCL-2 family: Regulators of cell death
-
Chao DT, Korsmeyer SJ. 1998. BCL-2 family: Regulators of cell death. Annu Rev Immunol 16:395-419.
-
(1998)
Annu Rev Immunol
, vol.16
, pp. 395-419
-
-
Chao, D.T.1
Korsmeyer, S.J.2
-
19
-
-
0036532162
-
Growth phase-dependent expression of ICAD-L/DFF45 modulates the pattern of apoptosis in human colonic cancer cells
-
Charrier L, Jarry A, Toquet C, Bou-Hanna C, Chedorge M, Denis M, Vallette G, Laboisse CL. 2002. Growth phase-dependent expression of ICAD-L/ DFF45 modulates the pattern of apoptosis in human colonic cancer cells. Cancer Res 62:2169-2174.
-
(2002)
Cancer Res
, vol.62
, pp. 2169-2174
-
-
Charrier, L.1
Jarry, A.2
Toquet, C.3
Bou-Hanna, C.4
Chedorge, M.5
Denis, M.6
Vallette, G.7
Laboisse, C.L.8
-
20
-
-
0031877779
-
Inhibition of caspase activity prevents anti-IgM induced apoptosis but not ceramide generation in WEHI 231 B cells
-
Chen L, Kim TJ, Pillai S. 1998. Inhibition of caspase activity prevents anti-IgM induced apoptosis but not ceramide generation in WEHI 231 B cells. Mol Immunol 35:195-205.
-
(1998)
Mol Immunol
, vol.35
, pp. 195-205
-
-
Chen, L.1
Kim, T.J.2
Pillai, S.3
-
21
-
-
0028095477
-
Apoptotic signaling through CD95 (Fas/Apo-1) activates an acidic sphingomyelinase
-
Cifone MG, De Maria R, Roncaioli P, Rippo MR, Azuma M, Lanier LL, Santoni A, Testi R. 1994. Apoptotic signaling through CD95 (Fas/Apo-1) activates an acidic sphingomyelinase. J Exp Med 180:1547-1552.
-
(1994)
J Exp Med
, vol.180
, pp. 1547-1552
-
-
Cifone, M.G.1
De Maria, R.2
Roncaioli, P.3
Rippo, M.R.4
Azuma, M.5
Lanier, L.L.6
Santoni, A.7
Testi, R.8
-
22
-
-
0027258466
-
Thymocyte apoptosis induced by p53-dependent and independent pathways
-
Clarke AR, Purdie CA, Harrison DJ, Morris RG, Bird CC, Hooper ML, Wyllie AH. 1993. Thymocyte apoptosis induced by p53-dependent and independent pathways. Nature 362:849-852.
-
(1993)
Nature
, vol.362
, pp. 849-852
-
-
Clarke, A.R.1
Purdie, C.A.2
Harrison, D.J.3
Morris, R.G.4
Bird, C.C.5
Hooper, M.L.6
Wyllie, A.H.7
-
23
-
-
0034278982
-
Modulation of the ceramide level, a novel therapeutic concept?
-
Claus R, Russwurm S, Meisner M, Kinscherf R, Deigner HP. 2000. Modulation of the ceramide level, a novel therapeutic concept? Curr Drug Targets 1:185-205.
-
(2000)
Curr Drug Targets
, vol.1
, pp. 185-205
-
-
Claus, R.1
Russwurm, S.2
Meisner, M.3
Kinscherf, R.4
Deigner, H.P.5
-
24
-
-
0033951633
-
Cervical cancer cells induce apoptosis of cytotoxic T lymphocytes
-
Contreras DN, Krammer PH, Potkul RK, Bu P, Rossi JL, Kaufmann AM, Gissmann L, Qiao L. 2000. Cervical cancer cells induce apoptosis of cytotoxic T lymphocytes. J Immunother 23:67-74.
-
(2000)
J Immunother
, vol.23
, pp. 67-74
-
-
Contreras, D.N.1
Krammer, P.H.2
Potkul, R.K.3
Bu, P.4
Rossi, J.L.5
Kaufmann, A.M.6
Gissmann, L.7
Qiao, L.8
-
26
-
-
0028672529
-
The p53 tumor suppressor gene inhibits angiogenesis by stimulating the production of thrombospondin
-
Dameron KM, Volpert OV, Tainsky MA, Bouck N. 1994. The p53 tumor suppressor gene inhibits angiogenesis by stimulating the production of thrombospondin. Cold Spring Harb Symp Quant Biol 59:483-489.
-
(1994)
Cold Spring Harb Symp Quant Biol
, vol.59
, pp. 483-489
-
-
Dameron, K.M.1
Volpert, O.V.2
Tainsky, M.A.3
Bouck, N.4
-
27
-
-
0034900902
-
The kiss of death: Promises and failures of death receptors and ligands in cancer therapy
-
Daniel PT, Wieder T, Sturm I, Schulze-Osthoff K. 2001. The kiss of death: Promises and failures of death receptors and ligands in cancer therapy. Leukemia 15:1022-1032.
-
(2001)
Leukemia
, vol.15
, pp. 1022-1032
-
-
Daniel, P.T.1
Wieder, T.2
Sturm, I.3
Schulze-Osthoff, K.4
-
28
-
-
0035875023
-
Apoptosis induction in cancer cells by a novel analogue of 6-[3-(1-adamantyl)-4-hydroxyphenyl]-2-naphthalenecarboxylic acid lacking retinoid receptor transcriptional activation activity
-
Dawson MI, Hobbs PD, Peterson VJ, Leid M, Lange CW, Feng KC, Chen G, Gu J, Li H, Kolluri SK, Zhang X, Zhang Y, Fontana JA. 2001. Apoptosis induction in cancer cells by a novel analogue of 6-[3-(1-adamantyl)-4-hydroxyphenyl]-2-naphthalenecarboxylic acid lacking retinoid receptor transcriptional activation activity. Cancer Res 61:4723-4730.
-
(2001)
Cancer Res
, vol.61
, pp. 4723-4730
-
-
Dawson, M.I.1
Hobbs, P.D.2
Peterson, V.J.3
Leid, M.4
Lange, C.W.5
Feng, K.C.6
Chen, G.7
Gu, J.8
Li, H.9
Kolluri, S.K.10
Zhang, X.11
Zhang, Y.12
Fontana, J.A.13
-
29
-
-
0025880967
-
Retinoids and their receptors in differentiation, embryogenesis, and neoplasia
-
De Luca LM. 1991. Retinoids and their receptors in differentiation, embryogenesis, and neoplasia. FASEB J 5:2924-2933.
-
(1991)
FASEB J
, vol.5
, pp. 2924-2933
-
-
De Luca, L.M.1
-
30
-
-
0026561121
-
Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours
-
Donehower LA, Harvey M, Slagle BL, McArthur MJ, Montgomery CA, Jr., Butel JS, Bradley A. 1992. Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours. Nature 356:215-221.
-
(1992)
Nature
, vol.356
, pp. 215-221
-
-
Donehower, L.A.1
Harvey, M.2
Slagle, B.L.3
McArthur, M.J.4
Montgomery Jr., C.A.5
Butel, J.S.6
Bradley, A.7
-
31
-
-
0033782260
-
Caspase pathways, neuronal apoptosis, and CNS injury
-
Eldadah BA, Faden AI. 2000. Caspase pathways, neuronal apoptosis, and CNS injury. J Neurotrauma 17:811-829.
-
(2000)
J Neurotrauma
, vol.17
, pp. 811-829
-
-
Eldadah, B.A.1
Faden, A.I.2
-
32
-
-
0028951326
-
Atypical apoptotic cell death induced in L929 targets by exposure to tumor necrosis factor
-
Fady C, Gardner A, Jacoby F, Briskin K, Tu Y, Schmid I, Lichtenstein A. 1995. Atypical apoptotic cell death induced in L929 targets by exposure to tumor necrosis factor. J Interferon Cytokine Res 15:71-80.
-
(1995)
J Interferon Cytokine Res
, vol.15
, pp. 71-80
-
-
Fady, C.1
Gardner, A.2
Jacoby, F.3
Briskin, K.4
Tu, Y.5
Schmid, I.6
Lichtenstein, A.7
-
33
-
-
0035736259
-
Organelle-specific initiation of cell death pathways
-
Ferri KF, Kroemer G. 2001. Organelle-specific initiation of cell death pathways. Nat Cell Biol 3:E255-263.
-
(2001)
Nat Cell Biol
, vol.3
-
-
Ferri, K.F.1
Kroemer, G.2
-
34
-
-
0030952902
-
Expression and regulation of Bcl-2, Bcl-xl, and Bax correlate with p53 status and sensitivity to apoptosis in childhood acute lymphoblastic leukemia
-
Findley HW, Gu L, Yeager AM, Zhou M. 1997. Expression and regulation of Bcl-2, Bcl-xl, and Bax correlate with p53 status and sensitivity to apoptosis in childhood acute lymphoblastic leukemia. Blood 89:2986-2993.
-
(1997)
Blood
, vol.89
, pp. 2986-2993
-
-
Findley, H.W.1
Gu, L.2
Yeager, A.M.3
Zhou, M.4
-
35
-
-
0029025441
-
Dominant interfering Fas gene mutations impair apoptosis in a human autoimmune lymphoproliferative syndrome
-
Fisher GH, Rosenberg FJ, Straus SE, Dale JK, Middleton LA, Lin AY, Strober W, Lenardo MJ, Puck JM. 1995. Dominant interfering Fas gene mutations impair apoptosis in a human autoimmune lymphoproliferative syndrome. Cell 81:935-946.
-
(1995)
Cell
, vol.81
, pp. 935-946
-
-
Fisher, G.H.1
Rosenberg, F.J.2
Straus, S.E.3
Dale, J.K.4
Middleton, L.A.5
Lin, A.Y.6
Strober, W.7
Lenardo, M.J.8
Puck, J.M.9
-
36
-
-
0034329854
-
Regulation by ceramide of epidermal growth factor signal transduction and mitogenesis in cell lines overexpressing the growth factor receptor
-
Gallardo G, Tabraue C, Quintana J, Lopez-Blanco F, Cabrera J, Diaz R, Estevez F, Ruiz de Galarreta CM, Fanjul LF, Santana P. 2000. Regulation by ceramide of epidermal growth factor signal transduction and mitogenesis in cell lines overexpressing the growth factor receptor. Cell Mol Biol (Noisy-le-grand) 46:1305-1312.
-
(2000)
Cell Mol Biol (Noisy-le-grand)
, vol.46
, pp. 1305-1312
-
-
Gallardo, G.1
Tabraue, C.2
Quintana, J.3
Lopez-Blanco, F.4
Cabrera, J.5
Diaz, R.6
Estevez, F.7
Ruiz De Galarreta, C.M.8
Fanjul, L.F.9
Santana, P.10
-
37
-
-
0028783367
-
Involvement of the CD95 (APO-1/Fas) receptor and ligand in liver damage
-
Galle PR, Hofmann WJ, Walczak H, Schaller H, Otto G, Stremmel W, Krammer PH, Runkel L. 1995. Involvement of the CD95 (APO-1/Fas) receptor and ligand in liver damage. J Exp Med 182:1223-1230.
-
(1995)
J Exp Med
, vol.182
, pp. 1223-1230
-
-
Galle, P.R.1
Hofmann, W.J.2
Walczak, H.3
Schaller, H.4
Otto, G.5
Stremmel, W.6
Krammer, P.H.7
Runkel, L.8
-
39
-
-
0033989422
-
Increased expression of death receptors 4 and 5 synergizes the apoptosis response to combined treatment with etoposide and TRAIL
-
Gibson SB, Oyer R, Spalding AC, Anderson SM, Johnson GL. 2000. Increased expression of death receptors 4 and 5 synergizes the apoptosis response to combined treatment with etoposide and TRAIL. Mol Cell Biol 20:205-212.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 205-212
-
-
Gibson, S.B.1
Oyer, R.2
Spalding, A.C.3
Anderson, S.M.4
Johnson, G.L.5
-
40
-
-
0030468789
-
Molecular, structural, and biological characteristics of the tumor necrosis factor ligand superfamily
-
Gruss HJ. 1996. Molecular, structural, and biological characteristics of the tumor necrosis factor ligand superfamily. Int J Clin Lab Res 26:143-159.
-
(1996)
Int J Clin Lab Res
, vol.26
, pp. 143-159
-
-
Gruss, H.J.1
-
41
-
-
0029031348
-
Apoptotic cell death induced by beta-amyloid 1-42 peptide is cell type dependent
-
Gschwind M, Huber G. 1995. Apoptotic cell death induced by beta-amyloid 1-42 peptide is cell type dependent. J Neurochem 65:292-300.
-
(1995)
J Neurochem
, vol.65
, pp. 292-300
-
-
Gschwind, M.1
Huber, G.2
-
42
-
-
0002020447
-
-
Sporn MB, Roberts AB, Goodman DS, editors. New York: Raven Press
-
Gudas L, Sporn M, Roberts A. 1994. Cellular biology and biochemistry of the retinoids. The retinoids. 2nd edition, Sporn MB, Roberts AB, Goodman DS, editors. New York: Raven Press. 443-520.
-
(1994)
Cellular Biology and Biochemistry of the Retinoids. The Retinoids. 2nd Edition
, pp. 443-520
-
-
Gudas, L.1
Sporn, M.2
Roberts, A.3
-
43
-
-
0032975247
-
The role of placental Fas ligand in maintaining immune privilege at maternal-fetal interfaces
-
Guller S, LaChapelle L. 1999. The role of placental Fas ligand in maintaining immune privilege at maternal-fetal interfaces. Semin Reprod Endocrinol 17:39-44.
-
(1999)
Semin Reprod Endocrinol
, vol.17
, pp. 39-44
-
-
Guller, S.1
LaChapelle, L.2
-
44
-
-
0034668184
-
c-Jun and the transcriptional control of neuronal apoptosis
-
Ham J, Eilers A, Whitfield J, Neame SJ, Shah B. 2000. c-Jun and the transcriptional control of neuronal apoptosis. Biochem Pharmacol 60:1015-1021.
-
(2000)
Biochem Pharmacol
, vol.60
, pp. 1015-1021
-
-
Ham, J.1
Eilers, A.2
Whitfield, J.3
Neame, S.J.4
Shah, B.5
-
45
-
-
0034528548
-
Regulation of MEF2 by p38 MAPK and its implication in cardiomyocyte biology
-
Han J, Molkentin JD. 2000. Regulation of MEF2 by p38 MAPK and its implication in cardiomyocyte biology. Trends Cardiovasc Med 10:19-22.
-
(2000)
Trends Cardiovasc Med
, vol.10
, pp. 19-22
-
-
Han, J.1
Molkentin, J.D.2
-
46
-
-
0034714355
-
Execution of apoptosis signal-regulating kinase 1 (ASK1)-induced apoptosis by the mitochondria-dependent caspase activation
-
Hatai T, Matsuzawa A, Inoshita S, Mochida Y, Kuroda T, Sakamaki K, Kuida K, Yonehara S, Ichijo H, Takeda K. 2000. Execution of apoptosis signal-regulating kinase 1 (ASK1)-induced apoptosis by the mitochondria-dependent caspase activation. J Biol Chem 275:26576-26581.
-
(2000)
J Biol Chem
, vol.275
, pp. 26576-26581
-
-
Hatai, T.1
Matsuzawa, A.2
Inoshita, S.3
Mochida, Y.4
Kuroda, T.5
Sakamaki, K.6
Kuida, K.7
Yonehara, S.8
Ichijo, H.9
Takeda, K.10
-
47
-
-
0034641918
-
The biochemistry of apoptosis
-
Hengartner MO. 2000. The biochemistry of apoptosis. Nature 407:770-776.
-
(2000)
Nature
, vol.407
, pp. 770-776
-
-
Hengartner, M.O.1
-
48
-
-
0028258577
-
Cytotoxic lymphocytes require granzyme B for the rapid induction of DNA fragmentation and apoptosis in allogeneic target cell
-
Heusel JW, Wesselschmidt RL, Shresta S, Russell JH, Ley TJ. 1994. Cytotoxic lymphocytes require granzyme B for the rapid induction of DNA fragmentation and apoptosis in allogeneic target cell. Cell 76:977-987.
-
(1994)
Cell
, vol.76
, pp. 977-987
-
-
Heusel, J.W.1
Wesselschmidt, R.L.2
Shresta, S.3
Russell, J.H.4
Ley, T.J.5
-
49
-
-
0028200655
-
Immunohistochemical detection of Fas antigen in liver tissue of patients with chronic hepatitis C
-
Hiramatsu N, Hayashi N, Katayama K, Mochizuki K, Kawanishi Y, Kasahara A, Fusamoto H, Kamada T. 1994. Immunohistochemical detection of Fas antigen in liver tissue of patients with chronic hepatitis C. Hepatology 19:1354-1359.
-
(1994)
Hepatology
, vol.19
, pp. 1354-1359
-
-
Hiramatsu, N.1
Hayashi, N.2
Katayama, K.3
Mochizuki, K.4
Kawanishi, Y.5
Kasahara, A.6
Fusamoto, H.7
Kamada, T.8
-
50
-
-
0034119019
-
Bcl-2 and Bax proteins are present in interphase nuclei of mammalian cells
-
Hoetelmans R, van Slooten HJ, Keijzer R, Erkeland S, van de Velde CJ, Dierendonck JH. 2000. Bcl-2 and Bax proteins are present in interphase nuclei of mammalian cells. Cell Death Differ 7:384-392.
-
(2000)
Cell Death Differ
, vol.7
, pp. 384-392
-
-
Hoetelmans, R.1
Van Slooten, H.J.2
Keijzer, R.3
Erkeland, S.4
Van De Velde, C.J.5
Dierendonck, J.H.6
-
51
-
-
0033842280
-
Induction of apoptosis in ovarian carcinoma cells by AHPN/CD437 is mediated by retinoic acid receptors
-
Holmes WF, Dawson MI, Soprano DR, Soprano KJ. 2000. Induction of apoptosis in ovarian carcinoma cells by AHPN/CD437 is mediated by retinoic acid receptors. J Cell Physiol 185:61-67.
-
(2000)
J Cell Physiol
, vol.185
, pp. 61-67
-
-
Holmes, W.F.1
Dawson, M.I.2
Soprano, D.R.3
Soprano, K.J.4
-
52
-
-
0037160102
-
Elucidation of molecular events mediating induction of apoptosis by synthetic retinoids using a CD437 resistant ovarian carcinoma cell line
-
Holmes WF, Soprano DR, Soprano KJ. 2002. Elucidation of molecular events mediating induction of apoptosis by synthetic retinoids using a CD437 resistant ovarian carcinoma cell line. J Biol Chem 277:45408-45419.
-
(2002)
J Biol Chem
, vol.277
, pp. 45408-45419
-
-
Holmes, W.F.1
Soprano, D.R.2
Soprano, K.J.3
-
53
-
-
0038034335
-
Comparison of the mechanism of induction of apoptosis in ovarian carcinoma cells by the conformationally restricted synthetic retinoids CD437 and 4-HPR
-
Holmes WF, Soprano DR, Soprano KJ. 2003a. Comparison of the mechanism of induction of apoptosis in ovarian carcinoma cells by the conformationally restricted synthetic retinoids CD437 and 4-HPR. J Cell Biochem 89:262-278.
-
(2003)
J Cell Biochem
, vol.89
, pp. 262-278
-
-
Holmes, W.F.1
Soprano, D.R.2
Soprano, K.J.3
-
54
-
-
0142135505
-
Early events in the induction of apoptosis in ovarian carcinoma cells by CD437: Activation of the p38 MAP kinase signal pathway
-
Holmes WF, Soprano DR, Soprano KJ. 2003b. Early events in the induction of apoptosis in ovarian carcinoma cells by CD437: Activation of the p38 MAP kinase signal pathway. Oncogene 22:6377-6386.
-
(2003)
Oncogene
, vol.22
, pp. 6377-6386
-
-
Holmes, W.F.1
Soprano, D.R.2
Soprano, K.J.3
-
55
-
-
0032515874
-
Bcl-XL interacts with Apaf-1 and inhibits Apaf-1-dependent caspase-9 activation
-
Hu Y, Benedict MA, Wu D, Inohara N, Nunez G. 1998. Bcl-XL interacts with Apaf-1 and inhibits Apaf-1-dependent caspase-9 activation. Proc Natl Acad Sci USA 95:4386-4391.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 4386-4391
-
-
Hu, Y.1
Benedict, M.A.2
Wu, D.3
Inohara, N.4
Nunez, G.5
-
56
-
-
0033212968
-
Triggering cell death: The crystal structure of Apo2L/TRAIL in a complex with death receptor 5
-
Hymowitz SG, Christinger HW, Fuh G, Ultsch M, O'Connell M, Kelley RF, Ashkenazi A, de Vos AM. 1999. Triggering cell death: The crystal structure of Apo2L/TRAIL in a complex with death receptor 5. Mol Cell 4:563-571.
-
(1999)
Mol Cell
, vol.4
, pp. 563-571
-
-
Hymowitz, S.G.1
Christinger, H.W.2
Fuh, G.3
Ultsch, M.4
O'Connell, M.5
Kelley, R.F.6
Ashkenazi, A.7
De Vos, A.M.8
-
57
-
-
15644363722
-
Diva, a Bcl-2 homologue that binds directly to Apaf-1 and induces BH3-independent cell death
-
Inohara N, Gourley TS, Carrio R, Muniz M, Merino J, Garcia I, Koseki T, Hu Y, Chen S, Nunez G. 1998. Diva, a Bcl-2 homologue that binds directly to Apaf-1 and induces BH3-independent cell death. J Biol Chem 273:32479-32486.
-
(1998)
J Biol Chem
, vol.273
, pp. 32479-32486
-
-
Inohara, N.1
Gourley, T.S.2
Carrio, R.3
Muniz, M.4
Merino, J.5
Garcia, I.6
Koseki, T.7
Hu, Y.8
Chen, S.9
Nunez, G.10
-
58
-
-
0034844231
-
Processing of tumor necrosis factor by the membrane-bound TNF-alpha-converting enzyme, but not its truncated soluble form
-
Itai T, Tanaka M, Nagata S. 2001. Processing of tumor necrosis factor by the membrane-bound TNF-alpha-converting enzyme, but not its truncated soluble form. Eur J Biochem 268:2074-2082.
-
(2001)
Eur J Biochem
, vol.268
, pp. 2074-2082
-
-
Itai, T.1
Tanaka, M.2
Nagata, S.3
-
59
-
-
0028930533
-
Role for ceramide in cell cycle arrest
-
Jayadev S, Liu B, Bielawska AE, Lee JY, Nazaire F, Pushkareva M, Obeid LM, Hannun YA. 1995. Role for ceramide in cell cycle arrest. J Biol Chem 270:2047-2052.
-
(1995)
J Biol Chem
, vol.270
, pp. 2047-2052
-
-
Jayadev, S.1
Liu, B.2
Bielawska, A.E.3
Lee, J.Y.4
Nazaire, F.5
Pushkareva, M.6
Obeid, L.M.7
Hannun, Y.A.8
-
60
-
-
0030696171
-
p53 expression overcomes p21WAF1/CIP1 mediated G1 arrest and induces apoptosis in human cancer cells
-
Kagawa S, Fujiwara T, Hizuta A, Yasuda T, Zhang WW, Roth JA, Tanaka N. 1997. p53 expression overcomes p21WAF1/CIP1 mediated G1 arrest and induces apoptosis in human cancer cells. Oncogene 15:1903-1909.
-
(1997)
Oncogene
, vol.15
, pp. 1903-1909
-
-
Kagawa, S.1
Fujiwara, T.2
Hizuta, A.3
Yasuda, T.4
Zhang, W.W.5
Roth, J.A.6
Tanaka, N.7
-
61
-
-
0034192466
-
Dual role of caspase-11 in mediating activation of caspase-1 and caspase-3 under pathological conditions
-
Kang SJ, Wang S, Hara H, Peterson EP, Namura S, Amin-Hanjani S, Huang Z, Srinivasan A, Tomaselli KJ, Thornberry NA, Moskowitz MA, Yuan J. 2000. Dual role of caspase-11 in mediating activation of caspase-1 and caspase-3 under pathological conditions. J Cell Biol 149:613-622.
-
(2000)
J Cell Biol
, vol.149
, pp. 613-622
-
-
Kang, S.J.1
Wang, S.2
Hara, H.3
Peterson, E.P.4
Namura, S.5
Amin-Hanjani, S.6
Huang, Z.7
Srinivasan, A.8
Tomaselli, K.J.9
Thornberry, N.A.10
Moskowitz, M.A.11
Yuan, J.12
-
62
-
-
0028795582
-
2 A crystal structure of an extracellular fragment of human CD40 ligand
-
Karpusas M, Hsu YM, Wang JH, Thompson J, Lederman S, Chess L, Thomas D. 1995. 2 A crystal structure of an extracellular fragment of human CD40 ligand. Structure 3:1426.
-
(1995)
Structure
, vol.3
, pp. 1426
-
-
Karpusas, M.1
Hsu, Y.M.2
Wang, J.H.3
Thompson, J.4
Lederman, S.5
Chess, L.6
Thomas, D.7
-
63
-
-
0033761543
-
ERK5 is a novel type of mitogen-activated protein kinase containing a transcriptional activation domain
-
Kasler HG, Victoria J, Duramad O, Winoto A. 2000. ERK5 is a novel type of mitogen-activated protein kinase containing a transcriptional activation domain. Mol Cell Biol 20:8382-8389.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 8382-8389
-
-
Kasler, H.G.1
Victoria, J.2
Duramad, O.3
Winoto, A.4
-
64
-
-
0029584593
-
Nonsteroid nuclear receptors: What are genetic studies telling us about their role in real life?
-
Kastner P, Mark M, Chambon P. 1995. Nonsteroid nuclear receptors: What are genetic studies telling us about their role in real life? Cell 83:859-869.
-
(1995)
Cell
, vol.83
, pp. 859-869
-
-
Kastner, P.1
Mark, M.2
Chambon, P.3
-
65
-
-
0028804857
-
Metalloproteinase-mediated release of human Fas ligand
-
Kayagaki N, Kawasaki A, Ebata T, Ohmoto H, Ikeda S, Inoue S, Yoshino K, Okumura K, Yagita H. 1995. Metalloproteinase-mediated release of human Fas ligand. J Exp Med 182:1777-1783.
-
(1995)
J Exp Med
, vol.182
, pp. 1777-1783
-
-
Kayagaki, N.1
Kawasaki, A.2
Ebata, T.3
Ohmoto, H.4
Ikeda, S.5
Inoue, S.6
Yoshino, K.7
Okumura, K.8
Yagita, H.9
-
66
-
-
0032436412
-
The CD95(APO-1/Fas)/CD95L system
-
Krammer PH. 1998. The CD95(APO-1/Fas)/CD95L system. Toxicol Lett 102-103:131-137.
-
(1998)
Toxicol Lett
, vol.102-103
, pp. 131-137
-
-
Krammer, P.H.1
-
67
-
-
0034068601
-
Mitochondrial control of cell death
-
Kroemer G, Reed JC. 2000. Mitochondrial control of cell death. Nat Med 6:513-519.
-
(2000)
Nat Med
, vol.6
, pp. 513-519
-
-
Kroemer, G.1
Reed, J.C.2
-
68
-
-
0035887142
-
Cross-resistance to the synthetic retinoid CD437 in a paclitaxel-resistant human ovarian carcinoma cell line is independent of the overexpression of retinoic acid receptor-gamma
-
Kumar A, Soprano DR, Parekh HK. 2001. Cross-resistance to the synthetic retinoid CD437 in a paclitaxel-resistant human ovarian carcinoma cell line is independent of the overexpression of retinoic acid receptor-gamma. Cancer Res 61:7552-7555.
-
(2001)
Cancer Res
, vol.61
, pp. 7552-7555
-
-
Kumar, A.1
Soprano, D.R.2
Parekh, H.K.3
-
69
-
-
0030583369
-
Clinical, immunological, and pathological consequences of Fas-deficient conditions
-
Le Deist F, Emile JF, Rieux-Laucat F, Benkerrou M, Roberts I, Brousse N, Fischer A. 1996. Clinical, immunological, and pathological consequences of Fas-deficient conditions. Lancet 348:719-723.
-
(1996)
Lancet
, vol.348
, pp. 719-723
-
-
Le Deist, F.1
Emile, J.F.2
Rieux-Laucat, F.3
Benkerrou, M.4
Roberts, I.5
Brousse, N.6
Fischer, A.7
-
70
-
-
0033542461
-
Bcl-2 targeted to the endoplasmic reticulum can inhibit apoptosis induced by Myc but not etoposide in Rat-1 fibroblasts
-
Lee ST, Hoeffich KP, Wasfy GW, Woodgett JR, Leber B, Andrews DW, Hedley DW, Penn LZ. 1999. Bcl-2 targeted to the endoplasmic reticulum can inhibit apoptosis induced by Myc but not etoposide in Rat-1 fibroblasts. Oncogene 18:3520-3528.
-
(1999)
Oncogene
, vol.18
, pp. 3520-3528
-
-
Lee, S.T.1
Hoeffich, K.P.2
Wasfy, G.W.3
Woodgett, J.R.4
Leber, B.5
Andrews, D.W.6
Hedley, D.W.7
Penn, L.Z.8
-
71
-
-
0027420929
-
Constitutive and induced expression of APO-1, a new member of the nerve growth factor/tumor necrosis factor receptor superfamily, in normal and neoplastic cells
-
Leithauser F, Dhein J, Mechtersheimer G, Koretz K, Bruderlein S, Henne C, Schmidt A, Debatin KM, Krammer PH, Moller P. 1993. Constitutive and induced expression of APO-1, a new member of the nerve growth factor/tumor necrosis factor receptor superfamily, in normal and neoplastic cells. Lab Invest 69:415-429.
-
(1993)
Lab Invest
, vol.69
, pp. 415-429
-
-
Leithauser, F.1
Dhein, J.2
Mechtersheimer, G.3
Koretz, K.4
Bruderlein, S.5
Henne, C.6
Schmidt, A.7
Debatin, K.M.8
Krammer, P.H.9
Moller, P.10
-
72
-
-
0031830509
-
Molecular determinants of AHPN (CD437)-induced growth arrest and apoptosis in human lung cancer cell lines
-
Li Y, Lin B, Agadir A, Liu R, Dawson MI, Reed JC, Fontana JA, Bost F, Hobbs PD, Zheng Y, Chen GQ, Shroot B, Mercola D, Zhang XK. 1998. Molecular determinants of AHPN (CD437)-induced growth arrest and apoptosis in human lung cancer cell lines. Mol Cell Biol 18:4719-4731.
-
(1998)
Mol Cell Biol
, vol.18
, pp. 4719-4731
-
-
Li, Y.1
Lin, B.2
Agadir, A.3
Liu, R.4
Dawson, M.I.5
Reed, J.C.6
Fontana, J.A.7
Bost, F.8
Hobbs, P.D.9
Zheng, Y.10
Chen, G.Q.11
Shroot, B.12
Mercola, D.13
Zhang, X.K.14
-
73
-
-
0034682890
-
Cytochrome c release and apoptosis induced by mitochondrial targeting of nuclear orphan receptor TR3
-
Li H, Kolluri SK, Gu J, Dawson MI, Cao X, Hobbs PD, Lin B, Chen G, Lu J, Lin F, Xie Z, Fontana JA, Reed JC, Zhang X. 2000. Cytochrome c release and apoptosis induced by mitochondrial targeting of nuclear orphan receptor TR3 [see Comments] [comment]. Science 289:1159-1164.
-
(2000)
Science
, vol.289
, pp. 1159-1164
-
-
Li, H.1
Kolluri, S.K.2
Gu, J.3
Dawson, M.I.4
Cao, X.5
Hobbs, P.D.6
Lin, B.7
Chen, G.8
Lu, J.9
Lin, F.10
Xie, Z.11
Fontana, J.A.12
Reed, J.C.13
Zhang, X.14
-
74
-
-
0034647525
-
Activation of p38 mitogen-activated protein kinase is required for tumor necrosis factor-alpha-supported proliferation of leukemia and lymphoma cell lines
-
Liu RY, Fan C, Liu G, Olashaw NE, Zuckerman KS. 2000. Activation of p38 mitogen-activated protein kinase is required for tumor necrosis factor-alpha-supported proliferation of leukemia and lymphoma cell lines. J Biol Chem 275:21086-21093.
-
(2000)
J Biol Chem
, vol.275
, pp. 21086-21093
-
-
Liu, R.Y.1
Fan, C.2
Liu, G.3
Olashaw, N.E.4
Zuckerman, K.S.5
-
75
-
-
0034970465
-
Thapsigargin-induced apoptosis involves Cabin1-MEF2-mediated induction of Nur77
-
Liu W, Youn HD, Liu JO. 2001. Thapsigargin-induced apoptosis involves Cabin1-MEF2-mediated induction of Nur77. Eur J Immunol 31:1757-1764.
-
(2001)
Eur J Immunol
, vol.31
, pp. 1757-1764
-
-
Liu, W.1
Youn, H.D.2
Liu, J.O.3
-
76
-
-
0034652598
-
Bcl-2: bax and bcl-2: Bcl-x ratios by image cytometric quantitation of immunohistochemical expression in ovarian carcinoma: Correlation with prognosis
-
Lohmann CM, League AA, Clark WS, Lawson D, DeRose PB, Cohen C. 2000. Bcl-2: bax and bcl-2: Bcl-x ratios by image cytometric quantitation of immunohistochemical expression in ovarian carcinoma: Correlation with prognosis. Cytometry 42:61-66.
-
(2000)
Cytometry
, vol.42
, pp. 61-66
-
-
Lohmann, C.M.1
League, A.A.2
Clark, W.S.3
Lawson, D.4
DeRose, P.B.5
Cohen, C.6
-
77
-
-
0025633582
-
Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms
-
Malkin D, Li FP, Strong LC, Fraumeni JF, Jr., Nelson CE, Kim DH, Kassel J, Gryka MA, Bischoff FZ, Tainsky MA, et al. 1990. Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms. Science 250:1233-1238.
-
(1990)
Science
, vol.250
, pp. 1233-1238
-
-
Malkin, D.1
Li, F.P.2
Strong, L.C.3
Fraumeni Jr., J.F.4
Nelson, C.E.5
Kim, D.H.6
Kassel, J.7
Gryka, M.A.8
Bischoff, F.Z.9
Tainsky, M.A.10
-
78
-
-
17144448793
-
The novel retinoid 6-[3-(1-adamantyl)-4-hydroxyphenyl]-2-naphtalene carboxylic acid can trigger apoptosis through a mitochondrial pathway independent of the nucleus
-
Marchetti P, Zamzami N, Joseph B, Schraen-Maschke S, Mereau-Richard C, Costantini P, Metivier D, Susin SA, Kroemer G, Formstecher P. 1999. The novel retinoid 6-[3-(1-adamantyl)-4-hydroxyphenyl]-2-naphtalene carboxylic acid can trigger apoptosis through a mitochondrial pathway independent of the nucleus. Cancer Res 59:6257-6266.
-
(1999)
Cancer Res
, vol.59
, pp. 6257-6266
-
-
Marchetti, P.1
Zamzami, N.2
Joseph, B.3
Schraen-Maschke, S.4
Mereau-Richard, C.5
Costantini, P.6
Metivier, D.7
Susin, S.A.8
Kroemer, G.9
Formstecher, P.10
-
79
-
-
0031905817
-
Differential regulation of TRAIL and CD95 ligand in transformed cells of the T and B lymphocyte lineage
-
Mariani SM, Krammer PH. 1998. Differential regulation of TRAIL and CD95 ligand in transformed cells of the T and B lymphocyte lineage. Eur J Immunol 28:973-982.
-
(1998)
Eur J Immunol
, vol.28
, pp. 973-982
-
-
Mariani, S.M.1
Krammer, P.H.2
-
80
-
-
0025743791
-
Overexpression and mutation of p53 in epithelial ovarian cancer
-
Marks JR, Davidoff AM, Kerns BJ, Humphrey PA, Pence JC, Dodge RK, Clarke-Pearson DL, Iglehart JD, Bast RC, Jr., Berchuck A. 1991. Overexpression and mutation of p53 in epithelial ovarian cancer. Cancer Res 51:2979-2984.
-
(1991)
Cancer Res
, vol.51
, pp. 2979-2984
-
-
Marks, J.R.1
Davidoff, A.M.2
Kerns, B.J.3
Humphrey, P.A.4
Pence, J.C.5
Dodge, R.K.6
Clarke-Pearson, D.L.7
Iglehart, J.D.8
Bast Jr., R.C.9
Berchuck, A.10
-
81
-
-
0037057629
-
Apoptosis initiated by Bcl-2-regulated caspase activation independently of the cytochrome c/Apaf-1/caspase-9 apoptosome
-
Marsden VS, O'Connor L, O'Reilly LA, Silke J, Metcalf D, Ekert PG, Huang DC, Cecconi F, Kuida K, Tomaselli KJ, Roy S, Nicholson DW, Vaux DL, Bouillet P, Adams JM, Strasser A. 2002. Apoptosis initiated by Bcl-2-regulated caspase activation independently of the cytochrome c/Apaf-1/caspase-9 apoptosome. Nature 419:634-637.
-
(2002)
Nature
, vol.419
, pp. 634-637
-
-
Marsden, V.S.1
O'Connor, L.2
O'Reilly, L.A.3
Silke, J.4
Metcalf, D.5
Ekert, P.G.6
Huang, D.C.7
Cecconi, F.8
Kuida, K.9
Tomaselli, K.J.10
Roy, S.11
Nicholson, D.W.12
Vaux, D.L.13
Bouillet, P.14
Adams, J.M.15
Strasser, A.16
-
82
-
-
0032211769
-
Signal transduction of stress via ceramide
-
Mathias S, Pena LA, Kolesnick RN. 1998. Signal transduction of stress via ceramide. Biochem J 335:465-480.
-
(1998)
Biochem J
, vol.335
, pp. 465-480
-
-
Mathias, S.1
Pena, L.A.2
Kolesnick, R.N.3
-
83
-
-
0035955454
-
Activation of the JAK/STAT pathway by ceramide in cultured human fibroblasts
-
Maziere C, Conte MA, Maziere JC. 2001. Activation of the JAK/STAT pathway by ceramide in cultured human fibroblasts. FEBS Lett 507:163-168.
-
(2001)
FEBS Lett
, vol.507
, pp. 163-168
-
-
Maziere, C.1
Conte, M.A.2
Maziere, J.C.3
-
84
-
-
0029007929
-
The roles of retinoids in vertebrate development
-
Means AL, Gudas LJ. 1995. The roles of retinoids in vertebrate development. Annu Rev Biochem 64:201-233.
-
(1995)
Annu Rev Biochem
, vol.64
, pp. 201-233
-
-
Means, A.L.1
Gudas, L.J.2
-
85
-
-
0035916380
-
Comparative characterization of cell death between Sf9 insect cells and hybridoma cultures
-
Meneses-Acosta A, Mendonca R, Merchant H, Covarrubias L, Ramirez O. 2001. Comparative characterization of cell death between Sf9 insect cells and hybridoma cultures. Biotechnol Bioeng 72:441-457.
-
(2001)
Biotechnol Bioeng
, vol.72
, pp. 441-457
-
-
Meneses-Acosta, A.1
Mendonca, R.2
Merchant, H.3
Covarrubias, L.4
Ramirez, O.5
-
86
-
-
0034101492
-
Caspase-3-dependent and caspase-3-independent pathways leading to chromatin DNA fragmentation in HL-60 cells
-
Meng XW, Fraser MJ, Feller JM, Ziegler JB. 2000. Caspase-3-dependent and caspase-3-independent pathways leading to chromatin DNA fragmentation in HL-60 cells. Apoptosis 5:61-67.
-
(2000)
Apoptosis
, vol.5
, pp. 61-67
-
-
Meng, X.W.1
Fraser, M.J.2
Feller, J.M.3
Ziegler, J.B.4
-
87
-
-
0035172034
-
Relationship of oncogenes (sFas, Bcl-2) and cytokines (IL-10, alfa-TNF) with the activity of systemic lupus erythematosus
-
Miret C, Font J, Molina R, Garcia-Carrasco M, Filella X, Ramos M, Cervera R, Ballesta A, Ingelmo M. 2001. Relationship of oncogenes (sFas, Bcl-2) and cytokines (IL-10, alfa-TNF) with the activity of systemic lupus erythematosus. Anticancer Res 21:3053-3059.
-
(2001)
Anticancer Res
, vol.21
, pp. 3053-3059
-
-
Miret, C.1
Font, J.2
Molina, R.3
Garcia-Carrasco, M.4
Filella, X.5
Ramos, M.6
Cervera, R.7
Ballesta, A.8
Ingelmo, M.9
-
88
-
-
0035511818
-
Apoptosis induced by FasL and TRAIL/Apo2L in the pathogenesis of thyroid diseases
-
Mitsiades N, Poulaki V, Mitsiades CS, Koutras DA, Chrousos GP. 2001. Apoptosis induced by FasL and TRAIL/Apo2L in the pathogenesis of thyroid diseases. Trends Endocrinol Metab 12:384-390.
-
(2001)
Trends Endocrinol Metab
, vol.12
, pp. 384-390
-
-
Mitsiades, N.1
Poulaki, V.2
Mitsiades, C.S.3
Koutras, D.A.4
Chrousos, G.P.5
-
89
-
-
0028883179
-
Tumor suppressor p53 is a direct transcriptional activator of the human bax gene
-
Miyashita T, Reed JC. 1995. Tumor suppressor p53 is a direct transcriptional activator of the human bax gene. Cell 80:293-299.
-
(1995)
Cell
, vol.80
, pp. 293-299
-
-
Miyashita, T.1
Reed, J.C.2
-
90
-
-
0028335717
-
Tumor suppressor p53 is a regulator of bcl-2 and bax gene expression in vitro and in vivo
-
Miyashita T, Krajewski S, Krajewska M, Wang HG, Lin HK, Liebermann DA, Hoffman B, Reed JC. 1994. Tumor suppressor p53 is a regulator of bcl-2 and bax gene expression in vitro and in vivo. Oncogene 9:1799-1805.
-
(1994)
Oncogene
, vol.9
, pp. 1799-1805
-
-
Miyashita, T.1
Krajewski, S.2
Krajewska, M.3
Wang, H.G.4
Lin, H.K.5
Liebermann, D.A.6
Hoffman, B.7
Reed, J.C.8
-
91
-
-
0032906263
-
The novel synthetic retinoid 6-[3-adamantyl-4-hydroxyphenyl]-2-naphthalene carboxylic acid (CD437) causes apoptosis in acute promyelocytic leukemia cells through rapid activation of caspases
-
Mologni L, Ponzanelli I, Bresciani F, Sardiello G, Bergamaschi D, Gianni M, Reichert U, Rambaldi A, Terao M, Garattini E. 1999. The novel synthetic retinoid 6-[3-adamantyl-4-hydroxyphenyl]-2-naphthalene carboxylic acid (CD437) causes apoptosis in acute promyelocytic leukemia cells through rapid activation of caspases. Blood 93:1045-1061.
-
(1999)
Blood
, vol.93
, pp. 1045-1061
-
-
Mologni, L.1
Ponzanelli, I.2
Bresciani, F.3
Sardiello, G.4
Bergamaschi, D.5
Gianni, M.6
Reichert, U.7
Rambaldi, A.8
Terao, M.9
Garattini, E.10
-
92
-
-
0003060912
-
-
Sporn MB, Roberts AB, Goodman DS, editors. Orlando, Florida: Academic Press
-
Moon R, Metha R, Rao K. 1994. Retinoids and cancer in experimental animals. The retinoids. 2nd edition. Sporn MB, Roberts AB, Goodman DS, editors. Orlando, Florida: Academic Press. 573-596.
-
(1994)
Retinoids and Cancer in Experimental Animals. The Retinoids. 2nd Edition
, pp. 573-596
-
-
Moon, R.1
Metha, R.2
Rao, K.3
-
93
-
-
0027232299
-
Overcoming tumor necrosis factor and drug resistance of human tumor cell lines by combination treatment with anti-Fas antibody and drugs or toxins
-
Morimoto H, Yonehara S, Bonavida B. 1993. Overcoming tumor necrosis factor and drug resistance of human tumor cell lines by combination treatment with anti-Fas antibody and drugs or toxins. Cancer Res 53:2591-2596.
-
(1993)
Cancer Res
, vol.53
, pp. 2591-2596
-
-
Morimoto, H.1
Yonehara, S.2
Bonavida, B.3
-
94
-
-
0033278987
-
Segregation of retinoic acid effects on fetal ovarian germ cell mitosis versus apoptosis by requirement for new macromolecular synthesis
-
Morita Y, Tilly JL. 1999. Segregation of retinoic acid effects on fetal ovarian germ cell mitosis versus apoptosis by requirement for new macromolecular synthesis. Endocrinology 140:2696-2703.
-
(1999)
Endocrinology
, vol.140
, pp. 2696-2703
-
-
Morita, Y.1
Tilly, J.L.2
-
95
-
-
0031743648
-
p53 activates the CD95 (APO-1/Fas) gene in response to DNA damage by anticancer drugs
-
Muller M, Wilder S, Bannasch D, Israeli D, Lehlbach K, Li-Weber M, Friedman SL, Galle PR, Stremmel W, Oren M, Krammer PH. 1998. p53 activates the CD95 (APO-1/Fas) gene in response to DNA damage by anticancer drugs. J Exp Med 188:2033-2045.
-
(1998)
J Exp Med
, vol.188
, pp. 2033-2045
-
-
Muller, M.1
Wilder, S.2
Bannasch, D.3
Israeli, D.4
Lehlbach, K.5
Li-Weber, M.6
Friedman, S.L.7
Galle, P.R.8
Stremmel, W.9
Oren, M.10
Krammer, P.H.11
-
96
-
-
0029841921
-
Tyrosine phosphorylation and activation of a new mitogen-activated protein (MAP)-kinase cascade in human neutrophils stimulated with various agonists
-
Nahas N, Molski TF, Fernandez GA, Sha'afi RI. 1996. Tyrosine phosphorylation and activation of a new mitogen-activated protein (MAP)-kinase cascade in human neutrophils stimulated with various agonists. Biochem J 318:247-253.
-
(1996)
Biochem J
, vol.318
, pp. 247-253
-
-
Nahas, N.1
Molski, T.F.2
Fernandez, G.A.3
Sha'afi, R.I.4
-
97
-
-
0034610743
-
Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta
-
Nakagawa T, Zhu H, Morishima N, Li E, Xu J, Yankner BA, Yuan J. 2000. Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta. Nature 403:98-103.
-
(2000)
Nature
, vol.403
, pp. 98-103
-
-
Nakagawa, T.1
Zhu, H.2
Morishima, N.3
Li, E.4
Xu, J.5
Yankner, B.A.6
Yuan, J.7
-
98
-
-
0036022188
-
Immune privilege in the anterior chamber of the eye
-
Niederkorn JY. 2002. Immune privilege in the anterior chamber of the eye. Crit Rev Immunol 22:13-46.
-
(2002)
Crit Rev Immunol
, vol.22
, pp. 13-46
-
-
Niederkorn, J.Y.1
-
99
-
-
0344389027
-
Caspases: The proteases of the apoptotic pathway
-
Nunez G, Benedict MA, Hu Y, Inohara N. 1998. Caspases: The proteases of the apoptotic pathway. Oncogene 17:3237-3245.
-
(1998)
Oncogene
, vol.17
, pp. 3237-3245
-
-
Nunez, G.1
Benedict, M.A.2
Hu, Y.3
Inohara, N.4
-
100
-
-
0029055676
-
Ceramide: A stress signal and mediator of growth suppression and apoptosis
-
Obeid LM, Hannun YA. 1995. Ceramide: A stress signal and mediator of growth suppression and apoptosis. J Cell Biochem 58:191-198.
-
(1995)
J Cell Biochem
, vol.58
, pp. 191-198
-
-
Obeid, L.M.1
Hannun, Y.A.2
-
101
-
-
0029993331
-
Apoptosis and the maintenance of homoeostasis in the immune system
-
Osborne BA. 1996. Apoptosis and the maintenance of homoeostasis in the immune system. Curr Opin Immunol 8:245-254.
-
(1996)
Curr Opin Immunol
, vol.8
, pp. 245-254
-
-
Osborne, B.A.1
-
102
-
-
0029648996
-
Soluble Fas/APO-1 in tumor cells: A potential regulator of apoptosis?
-
Owen-Schaub LB, Angelo LS, Radinsky R, Ware CF, Gesner TG, Bartos DP. 1995. Soluble Fas/APO-1 in tumor cells: A potential regulator of apoptosis? Cancer Lett 94:1-8.
-
(1995)
Cancer Lett
, vol.94
, pp. 1-8
-
-
Owen-Schaub, L.B.1
Angelo, L.S.2
Radinsky, R.3
Ware, C.F.4
Gesner, T.G.5
Bartos, D.P.6
-
103
-
-
0034654517
-
The role of Apaf-1, caspase-9, and bid proteins in etoposide- or paclitaxel-induced mitochondrial events during apoptosis
-
Perkins CL, Fang G, Kim CN, Bhalla KN. 2000. The role of Apaf-1, caspase-9, and bid proteins in etoposide- or paclitaxel-induced mitochondrial events during apoptosis. Cancer Res 60:1645-1653.
-
(2000)
Cancer Res
, vol.60
, pp. 1645-1653
-
-
Perkins, C.L.1
Fang, G.2
Kim, C.N.3
Bhalla, K.N.4
-
104
-
-
0034656396
-
Isolation and characterization of an acute promyelocytic leukemia cell line selectively resistant to the novel antileukemic and apoptogenic retinoid 6-[3-adamantyl-4-hydroxyphenyl]-2-naphthalene carboxylic acid
-
Ponzanelli I, Gianni M, Giavazzi R, Garofalo A, Nicoletti I, Reichert U, Erba E, Rambaldi A, Terao M, Garattini E. 2000. Isolation and characterization of an acute promyelocytic leukemia cell line selectively resistant to the novel antileukemic and apoptogenic retinoid 6-[3-adamantyl-4-hydroxyphenyl]-2-naphthalene carboxylic acid. Blood 95:2672-2682.
-
(2000)
Blood
, vol.95
, pp. 2672-2682
-
-
Ponzanelli, I.1
Gianni, M.2
Giavazzi, R.3
Garofalo, A.4
Nicoletti, I.5
Reichert, U.6
Erba, E.7
Rambaldi, A.8
Terao, M.9
Garattini, E.10
-
105
-
-
0029007640
-
Ceramide: An endogenous regulator of apoptosis and growth suppression
-
Pushkareva M, Obeid LM, Hannun YA. 1995. Ceramide: An endogenous regulator of apoptosis and growth suppression. Immunol Today 16:294-297.
-
(1995)
Immunol Today
, vol.16
, pp. 294-297
-
-
Pushkareva, M.1
Obeid, L.M.2
Hannun, Y.A.3
-
106
-
-
0037134503
-
Tumor suppressor p53 mediates apoptotic cell death triggered by cyclosporin A
-
Pyrzynska B, Serrano M, Martinez AC, Kaminska B. 2002. Tumor suppressor p53 mediates apoptotic cell death triggered by cyclosporin A. J Biol Chem 277:14102-14108.
-
(2002)
J Biol Chem
, vol.277
, pp. 14102-14108
-
-
Pyrzynska, B.1
Serrano, M.2
Martinez, A.C.3
Kaminska, B.4
-
107
-
-
0035720233
-
The Bax/Bcl-2 ratio determines the susceptibility of human melanoma cells to CD95/Fas-mediated apoptosis
-
Raisova M, Hossini AM, Eberle J, Riebeling C, Wieder T, Sturm I, Daniel PT, Orfanos CE, Geilen CC. 2001. The Bax/Bcl-2 ratio determines the susceptibility of human melanoma cells to CD95/Fas-mediated apoptosis. J Invest Dermatol 117:333-340.
-
(2001)
J Invest Dermatol
, vol.117
, pp. 333-340
-
-
Raisova, M.1
Hossini, A.M.2
Eberle, J.3
Riebeling, C.4
Wieder, T.5
Sturm, I.6
Daniel, P.T.7
Orfanos, C.E.8
Geilen, C.C.9
-
108
-
-
0034796867
-
Correlation of p53 mutations with resistance to platinum-based chemotherapy and shortened survival in ovarian cancer
-
Reles A, Wen WH, Schmider A, Gee C, Runnebaum IB, Kilian U, Jones LA, El-Naggar A, Minguillon C, Schonborn I, Reich O, Kreienberg R, Lichtenegger W, Press MF. 2001. Correlation of p53 mutations with resistance to platinum-based chemotherapy and shortened survival in ovarian cancer. Clin Cancer Res 7:2984-2997.
-
(2001)
Clin Cancer Res
, vol.7
, pp. 2984-2997
-
-
Reles, A.1
Wen, W.H.2
Schmider, A.3
Gee, C.4
Runnebaum, I.B.5
Kilian, U.6
Jones, L.A.7
El-Naggar, A.8
Minguillon, C.9
Schonborn, I.10
Reich, O.11
Kreienberg, R.12
Lichtenegger, W.13
Press, M.F.14
-
109
-
-
0028896092
-
The gene for neuronal apoptosis inhibitory protein is partially deleted in individuals with spinal muscular atrophy
-
Roy N, Mahadevan MS, McLean M, Shutler G, Yaraghi Z, Farahani R, Baird S, Besner-Johnston A, Lefebvre C, Kang X, et al. 1995. The gene for neuronal apoptosis inhibitory protein is partially deleted in individuals with spinal muscular atrophy. Cell 80:167-178.
-
(1995)
Cell
, vol.80
, pp. 167-178
-
-
Roy, N.1
Mahadevan, M.S.2
McLean, M.3
Shutler, G.4
Yaraghi, Z.5
Farahani, R.6
Baird, S.7
Besner-Johnston, A.8
Lefebvre, C.9
Kang, X.10
-
110
-
-
0034882639
-
Ceramide regulates cellular homeostasis via diverse stress signaling pathways
-
Ruvolo PP. 2001. Ceramide regulates cellular homeostasis via diverse stress signaling pathways. Leukemia 15:1153-1160.
-
(2001)
Leukemia
, vol.15
, pp. 1153-1160
-
-
Ruvolo, P.P.1
-
111
-
-
0035036135
-
Induction of Egr-1 expression by the retinoid AHPN in human lung carcinoma cells is dependent on activated ERK 1/2
-
Sakaue M, Adachi H, Dawson M, Jetten AM. 2001. Induction of Egr-1 expression by the retinoid AHPN in human lung carcinoma cells is dependent on activated ERK 1/2. Cell Death Differ 8:411-424.
-
(2001)
Cell Death Differ
, vol.8
, pp. 411-424
-
-
Sakaue, M.1
Adachi, H.2
Dawson, M.3
Jetten, A.M.4
-
112
-
-
0029007405
-
A subset of p53-deficient embryos exhibit exencephaly
-
Sah VP, Attardi LD, Mulligan GJ, Williams BO, Bronson RT, Jacks T. 1995. A subset of p53-deficient embryos exhibit exencephaly. Nat Genet 10:175-180.
-
(1995)
Nat Genet
, vol.10
, pp. 175-180
-
-
Sah, V.P.1
Attardi, L.D.2
Mulligan, G.J.3
Williams, B.O.4
Bronson, R.T.5
Jacks, T.6
-
113
-
-
0030877330
-
An ELISA for detection of apoptosis
-
Salgame P, Varadhachary AS, Primiano LL, Fincke JE, Muller S, Monestier M. 1997. An ELISA for detection of apoptosis. Nucleic Acids Res 25:680-681.
-
(1997)
Nucleic Acids Res
, vol.25
, pp. 680-681
-
-
Salgame, P.1
Varadhachary, A.S.2
Primiano, L.L.3
Fincke, J.E.4
Muller, S.5
Monestier, M.6
-
114
-
-
0036679169
-
Cell stress and MEKK1-mediated c-Jun activation modulate NFkappaB activity and cell viability
-
Sanchez-Perez I, Benitah SA, Martinez-Gomariz M, Lacal JC, Perona R. 2002. Cell stress and MEKK1-mediated c-Jun activation modulate NFkappaB activity and cell viability. Mol Biol Cell 13:2933-2945.
-
(2002)
Mol Biol Cell
, vol.13
, pp. 2933-2945
-
-
Sanchez-Perez, I.1
Benitah, S.A.2
Martinez-Gomariz, M.3
Lacal, J.C.4
Perona, R.5
-
115
-
-
0034641931
-
Corpse clearance defines the meaning of cell death
-
Savill J, Fadok V. 2000. Corpse clearance defines the meaning of cell death. Nature 407:784-788.
-
(2000)
Nature
, vol.407
, pp. 784-788
-
-
Savill, J.1
Fadok, V.2
-
116
-
-
0034037333
-
Apoptosis induced by death receptors
-
Schneider P, Tschopp J. 2000. Apoptosis induced by death receptors. Pharm Acta Helv 74:281-286.
-
(2000)
Pharm Acta Helv
, vol.74
, pp. 281-286
-
-
Schneider, P.1
Tschopp, J.2
-
117
-
-
0030707811
-
Characterization of two receptors for TRAIL
-
Schneider P, Bodmer JL, Thome M, Hofmann K, Holler N, Tschopp J. 1997. Characterization of two receptors for TRAIL. FEBS Lett 416:329-334.
-
(1997)
FEBS Lett
, vol.416
, pp. 329-334
-
-
Schneider, P.1
Bodmer, J.L.2
Thome, M.3
Hofmann, K.4
Holler, N.5
Tschopp, J.6
-
118
-
-
0032526268
-
Apoptosis signaling by death receptors
-
Schulze-Osthoff K, Ferrari D, Los M, Wesselborg S, Peter ME. 1998. Apoptosis signaling by death receptors. Eur J Biochem 254:439-459.
-
(1998)
Eur J Biochem
, vol.254
, pp. 439-459
-
-
Schulze-Osthoff, K.1
Ferrari, D.2
Los, M.3
Wesselborg, S.4
Peter, M.E.5
-
119
-
-
0028238213
-
Immediate early upregulation of bax expression by p53 but not TGF beta 1: A paradigm for distinct apoptotic pathways
-
Selvakumaran M, Lin HK, Miyashita T, Wang HG, Krajewski S, Reed JC, Hoffman B, Liebermann D. 1994. Immediate early upregulation of bax expression by p53 but not TGF beta 1: A paradigm for distinct apoptotic pathways. Oncogene 9:1791-1798.
-
(1994)
Oncogene
, vol.9
, pp. 1791-1798
-
-
Selvakumaran, M.1
Lin, H.K.2
Miyashita, T.3
Wang, H.G.4
Krajewski, S.5
Reed, J.C.6
Hoffman, B.7
Liebermann, D.8
-
120
-
-
0026523778
-
Induction of apoptosis by wild-type p53 in a human colon tumor-derived cell line
-
Shaw P, Bovey R, Tardy S, Sahli R, Sordat B, Costa J. 1992. Induction of apoptosis by wild-type p53 in a human colon tumor-derived cell line. Proc Natl Acad Sci USA 89:4495-4499.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 4495-4499
-
-
Shaw, P.1
Bovey, R.2
Tardy, S.3
Sahli, R.4
Sordat, B.5
Costa, J.6
-
121
-
-
0034724190
-
BH4 domain of antiapoptotic Bcl-2 family members closes voltage-dependent anion channel and inhibits apoptotic mitochondrial changes and cell death
-
Shimizu S, Konishi A, Kodama T, Tsujimoto Y. 2000. BH4 domain of antiapoptotic Bcl-2 family members closes voltage-dependent anion channel and inhibits apoptotic mitochondrial changes and cell death. Proc Natl Acad Sci USA 97:3100-3105.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 3100-3105
-
-
Shimizu, S.1
Konishi, A.2
Kodama, T.3
Tsujimoto, Y.4
-
122
-
-
0031282397
-
A role for JNK/SAPK in proliferation, but not apoptosis, of IL-3-dependent cells
-
Smith A, Ramos-Morales F, Ashworth A, Collins M. 1997. A role for JNK/SAPK in proliferation, but not apoptosis, of IL-3-dependent cells. Curr Biol 7:893-896.
-
(1997)
Curr Biol
, vol.7
, pp. 893-896
-
-
Smith, A.1
Ramos-Morales, F.2
Ashworth, A.3
Collins, M.4
-
123
-
-
0032242263
-
Apoptosis: Molecular mechanisms
-
Solary E. 1998. Apoptosis: Molecular mechanisms. C R Seances Soc Biol Fil 192:1065-1076.
-
(1998)
C R Seances Soc Biol Fil
, vol.192
, pp. 1065-1076
-
-
Solary, E.1
-
124
-
-
0025648762
-
Germ-line transmission of a mutated p53 gene in a cancer-prone family with Li-Fraumeni syndrome
-
Srivastava S, Zou ZQ, Pirollo K, Blattner W, Chang EH. 1990. Germ-line transmission of a mutated p53 gene in a cancer-prone family with Li-Fraumeni syndrome. Nature 348:747-749.
-
(1990)
Nature
, vol.348
, pp. 747-749
-
-
Srivastava, S.1
Zou, Z.Q.2
Pirollo, K.3
Blattner, W.4
Chang, E.H.5
-
125
-
-
0037173741
-
Activation of mitochondrial voltage-dependent anion channel by apro-apoptotic BH3-only protein Bim
-
Sugiyama T, Shimizu S, Matsuoka Y, Yoneda Y, Tsujimoto Y. 2002. Activation of mitochondrial voltage-dependent anion channel by apro-apoptotic BH3-only protein Bim. Oncogene 21:4944-4956.
-
(2002)
Oncogene
, vol.21
, pp. 4944-4956
-
-
Sugiyama, T.1
Shimizu, S.2
Matsuoka, Y.3
Yoneda, Y.4
Tsujimoto, Y.5
-
126
-
-
0033523876
-
Implication of mitochondria-derived reactive oxygen species, cytochrome C and caspase-3 in N-(4-hydroxyphenyl)retinamide-induced apoptosis in cervical carcinoma cells
-
Suzuki S, Higuchi M, Proske RJ, Oridate N, Hong WK, Lotan R. 1999. Implication of mitochondria-derived reactive oxygen species, cytochrome C and caspase-3 in N-(4-hydroxyphenyl)retinamide-induced apoptosis in cervical carcinoma cells. Oncogene 18:6380-6387.
-
(1999)
Oncogene
, vol.18
, pp. 6380-6387
-
-
Suzuki, S.1
Higuchi, M.2
Proske, R.J.3
Oridate, N.4
Hong, W.K.5
Lotan, R.6
-
127
-
-
0029147749
-
Alteration in the retinoid specificity of retinoic acid receptor-beta by site-directed mutagenesis of Arg269 and Lys220
-
Tairis N, Gabriel JL, Soprano KJ, Soprano DR. 1995. Alteration in the retinoid specificity of retinoic acid receptor-beta by site-directed mutagenesis of Arg269 and Lys220. J Biol Chem 270:18380-18387.
-
(1995)
J Biol Chem
, vol.270
, pp. 18380-18387
-
-
Tairis, N.1
Gabriel, J.L.2
Soprano, K.J.3
Soprano, D.R.4
-
128
-
-
0033769891
-
Apoptosis induced by dithiothreitol in HL-60 cells shows early activation of caspase 3 and is independent of mitochondria
-
Tartier L, McCarey YL, Biaglow JE, Kochevar IE, Held KD. 2000. Apoptosis induced by dithiothreitol in HL-60 cells shows early activation of caspase 3 and is independent of mitochondria. Cell Death Differ 7:1002-1010.
-
(2000)
Cell Death Differ
, vol.7
, pp. 1002-1010
-
-
Tartier, L.1
McCarey, Y.L.2
Biaglow, J.E.3
Kochevar, I.E.4
Held, K.D.5
-
129
-
-
0002443731
-
The molecular basis of ovarian cell death during germ cell attrition, follicular atresia, and luteolysis
-
Tilly JL. 1996. The molecular basis of ovarian cell death during germ cell attrition, follicular atresia, and luteolysis. Front Biosci 1:d1-d11.
-
(1996)
Front Biosci
, vol.1
-
-
Tilly, J.L.1
-
130
-
-
0032418092
-
Role of Bcl-2 family proteins in apoptosis: Apoptosomes or mitochondria?
-
Tsujimoto Y. 1998. Role of Bcl-2 family proteins in apoptosis: Apoptosomes or mitochondria? Genes Cells 3:697-707.
-
(1998)
Genes Cells
, vol.3
, pp. 697-707
-
-
Tsujimoto, Y.1
-
131
-
-
0021821903
-
Involvement of the bcl-2 gene in human follicular lymphoma
-
Tsujimoto Y, Cossman J, Jaffe E, Croce CM. 1985. Involvement of the bcl-2 gene in human follicular lymphoma. Science 228:1440-1443.
-
(1985)
Science
, vol.228
, pp. 1440-1443
-
-
Tsujimoto, Y.1
Cossman, J.2
Jaffe, E.3
Croce, C.M.4
-
132
-
-
0033258120
-
Bcl-2 proteins: Regulators of apoptosis or of mitochondrial homeostasis?
-
Vander Heiden MG, Thompson CB. 1999. Bcl-2 proteins: Regulators of apoptosis or of mitochondrial homeostasis? Nat Cell Biol 1:E209-E216.
-
(1999)
Nat Cell Biol
, vol.1
-
-
Vander Heiden, M.G.1
Thompson, C.B.2
-
133
-
-
0032738099
-
Crystal structure of Apaf-1 caspase recruitment domain: An alpha-helical Greek key fold for apoptotic signaling
-
Vaughn DE, Rodriguez J, Lazebnik Y, Joshua-Tor L. 1999. Crystal structure of Apaf-1 caspase recruitment domain: An alpha-helical Greek key fold for apoptotic signaling. J Mol Biol 293:439-447.
-
(1999)
J Mol Biol
, vol.293
, pp. 439-447
-
-
Vaughn, D.E.1
Rodriguez, J.2
Lazebnik, Y.3
Joshua-Tor, L.4
-
134
-
-
0028034199
-
Myc-mediated apoptosis requires wild-type p53 in a manner independent of cell cycle arrest and the ability of p53 to induce p21waf1/cip1
-
Wagner AJ, Kokontis JM, Hay N. 1994. Myc-mediated apoptosis requires wild-type p53 in a manner independent of cell cycle arrest and the ability of p53 to induce p21waf1/cip1. Genes Dev 8:2817-2830.
-
(1994)
Genes Dev
, vol.8
, pp. 2817-2830
-
-
Wagner, A.J.1
Kokontis, J.M.2
Hay, N.3
-
135
-
-
0034630161
-
The CD95 (APO-1/Fas) and the TRAIL (APO-2L) apoptosis systems
-
Walczak H, Krammer PH. 2000. The CD95 (APO-1/Fas) and the TRAIL (APO-2L) apoptosis systems. Exp Cell Res 256:58-66.
-
(2000)
Exp Cell Res
, vol.256
, pp. 58-66
-
-
Walczak, H.1
Krammer, P.H.2
-
136
-
-
0032777102
-
Cell death induced by the Fas/Fas ligand pathway and its role in pathology
-
Waring P, Mullbacher A. 1999. Cell death induced by the Fas/Fas ligand pathway and its role in pathology. Immunol Cell Biol 77:312-317.
-
(1999)
Immunol Cell Biol
, vol.77
, pp. 312-317
-
-
Waring, P.1
Mullbacher, A.2
-
137
-
-
0026568919
-
Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis
-
Watanabe-Fukunaga R, Brannan CI, Copeland NG, Jenkins NA, Nagata S. 1992. Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis. Nature 356:314-317.
-
(1992)
Nature
, vol.356
, pp. 314-317
-
-
Watanabe-Fukunaga, R.1
Brannan, C.I.2
Copeland, N.G.3
Jenkins, N.A.4
Nagata, S.5
-
138
-
-
0031954631
-
MEK kinase 1, a substrate for DEVD-directed caspases, is involved in genotoxin-induced apoptosis
-
Widmann C, Gerwins P, Johnson NL, Jarpe MB, Johnson GL. 1998. MEK kinase 1, a substrate for DEVD-directed caspases, is involved in genotoxin-induced apoptosis. Mol Cell Biol 18:2416-2429.
-
(1998)
Mol Cell Biol
, vol.18
, pp. 2416-2429
-
-
Widmann, C.1
Gerwins, P.2
Johnson, N.L.3
Jarpe, M.B.4
Johnson, G.L.5
-
139
-
-
0034948731
-
Ceramide-induced apoptosis in cortical neurons is mediated by an increase in p38 phosphorylation and not by the decrease in ERK phosphorylation
-
Willaime S, Vanhoutte P, Caboche J, Lemaigre-Dubreuil Y, Mariani J, Brugg B. 2001. Ceramide-induced apoptosis in cortical neurons is mediated by an increase in p38 phosphorylation and not by the decrease in ERK phosphorylation. Eur J Neurosci 13:2037-2046.
-
(2001)
Eur J Neurosci
, vol.13
, pp. 2037-2046
-
-
Willaime, S.1
Vanhoutte, P.2
Caboche, J.3
Lemaigre-Dubreuil, Y.4
Mariani, J.5
Brugg, B.6
-
140
-
-
0033575255
-
Suicidal tendencies: Apoptotic cell death by caspase family proteinases
-
Wolf BB, Green DR. 1999. Suicidal tendencies: Apoptotic cell death by caspase family proteinases. J Biol Chem 274:20049-20052.
-
(1999)
J Biol Chem
, vol.274
, pp. 20049-20052
-
-
Wolf, B.B.1
Green, D.R.2
-
141
-
-
0032890441
-
Differential expression of cell survival and cell cycle regulatory proteins in cutaneous squamoproliferative lesions
-
Wrone-Smith T, Bergstrom J, Quevedo ME, Reddy V, Gutierrez-Steil C, Nickoloff BJ. 1999. Differential expression of cell survival and cell cycle regulatory proteins in cutaneous squamoproliferative lesions. J Dermatol Sci 19:53-67.
-
(1999)
J Dermatol Sci
, vol.19
, pp. 53-67
-
-
Wrone-Smith, T.1
Bergstrom, J.2
Quevedo, M.E.3
Reddy, V.4
Gutierrez-Steil, C.5
Nickoloff, B.J.6
-
142
-
-
0031149830
-
All-trans-retinoic acid blocks cell cycle progression of human ovarian adenocarcinoma cells at late G1
-
Wu S, Donigan A, Platsoucas CD, Jung W, Soprano DR, Soprano KJ. 1997a. All-trans-retinoic acid blocks cell cycle progression of human ovarian adenocarcinoma cells at late G1. Exp Cell Res 232:277-286.
-
(1997)
Exp Cell Res
, vol.232
, pp. 277-286
-
-
Wu, S.1
Donigan, A.2
Platsoucas, C.D.3
Jung, W.4
Soprano, D.R.5
Soprano, K.J.6
-
143
-
-
0031586588
-
Reduction of both RAR and RXR levels is required to maximally alter sensitivity of CA-OV3 ovarian tumor cells to growth suppression by all-trans-retinoic acid
-
Wu S, Zhang ZP, Zhang D, Soprano DR, Soprano KJ. 1997b. Reduction of both RAR and RXR levels is required to maximally alter sensitivity of CA-OV3 ovarian tumor cells to growth suppression by all-trans-retinoic acid. Exp Cell Res 237:118-126.
-
(1997)
Exp Cell Res
, vol.237
, pp. 118-126
-
-
Wu, S.1
Zhang, Z.P.2
Zhang, D.3
Soprano, D.R.4
Soprano, K.J.5
-
144
-
-
0032030722
-
Effects of conformationally restricted synthetic retinoids on ovarian tumor cell growth
-
Wu S, Zhang D, Donigan A, Dawson MI, Soprano DR, Soprano KJ. 1998a. Effects of conformationally restricted synthetic retinoids on ovarian tumor cell growth. J Cell Biochem 68:378-388.
-
(1998)
J Cell Biochem
, vol.68
, pp. 378-388
-
-
Wu, S.1
Zhang, D.2
Donigan, A.3
Dawson, M.I.4
Soprano, D.R.5
Soprano, K.J.6
-
145
-
-
0032481136
-
Critical role of both retinoid nuclear receptors and retinoid-X-receptors in mediating growth inhibition of ovarian cancer cells by all-trans retinoic acid
-
Wu S, Zhang D, Zhang ZP, Soprano DR, Soprano KJ. 1998b. Critical role of both retinoid nuclear receptors and retinoid-X-receptors in mediating growth inhibition of ovarian cancer cells by all-trans retinoic acid. Oncogene 17:2839-2849.
-
(1998)
Oncogene
, vol.17
, pp. 2839-2849
-
-
Wu, S.1
Zhang, D.2
Zhang, Z.P.3
Soprano, D.R.4
Soprano, K.J.5
-
146
-
-
0030700659
-
Fas ligand is not only expressed in immune privileged human organs but is also coexpressed with Fas in various epithelial tissues
-
Xerri L, Devilard E, Hassoun J, Mawas C, Birg F. 1997. Fas ligand is not only expressed in immune privileged human organs but is also coexpressed with Fas in various epithelial tissues. Mol Pathol 50:87-91.
-
(1997)
Mol Pathol
, vol.50
, pp. 87-91
-
-
Xerri, L.1
Devilard, E.2
Hassoun, J.3
Mawas, C.4
Birg, F.5
-
147
-
-
0033011595
-
Targeting of p38 mitogen-activated protein kinases to MEF2 transcription factors
-
Yang SH, Galanis A, Sharrocks AD. 1999. Targeting of p38 mitogen-activated protein kinases to MEF2 transcription factors. Mol Cell Biol 19:4028-4038.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 4028-4038
-
-
Yang, S.H.1
Galanis, A.2
Sharrocks, A.D.3
-
148
-
-
0035957929
-
Activation of caspase-12, an endoplastic reticulum (ER) resident caspase, through tumor necrosis factor receptor-associated factor 2-dependent mechanism in response to the ER stress
-
Yoneda T, Imaizumi K, Oono K, Yui D, Gomi F, Katayama T, Tohyama M. 2001. Activation of caspase-12, an endoplastic reticulum (ER) resident caspase, through tumor necrosis factor receptor-associated factor 2-dependent mechanism in response to the ER stress. J Biol Chem 276:13935-13940.
-
(2001)
J Biol Chem
, vol.276
, pp. 13935-13940
-
-
Yoneda, T.1
Imaizumi, K.2
Oono, K.3
Yui, D.4
Gomi, F.5
Katayama, T.6
Tohyama, M.7
-
149
-
-
0025784539
-
Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6
-
Yonish-Rouach E, Resnitzky D, Lotem J, Sachs L, Kimchi A, Oren M. 1991. Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6. Nature 352:345-347.
-
(1991)
Nature
, vol.352
, pp. 345-347
-
-
Yonish-Rouach, E.1
Resnitzky, D.2
Lotem, J.3
Sachs, L.4
Kimchi, A.5
Oren, M.6
-
150
-
-
0033681541
-
Cabin1 represses MEF2-dependent Nur77 expression and T cell apoptosis by controlling association of histone deacetylases and acetylases with MEF2
-
Youn HD, Liu JO. 2000. Cabin1 represses MEF2-dependent Nur77 expression and T cell apoptosis by controlling association of histone deacetylases and acetylases with MEF2. Immunity 13:85-94.
-
(2000)
Immunity
, vol.13
, pp. 85-94
-
-
Youn, H.D.1
Liu, J.O.2
-
151
-
-
0033595816
-
Apoptosis of T cells mediated by Ca2+-induced release of the transcription factor MEF2
-
Youn HD, Sun L, Prywes R, Liu JO. 1999. Apoptosis of T cells mediated by Ca2+-induced release of the transcription factor MEF2. Science 286:790-793.
-
(1999)
Science
, vol.286
, pp. 790-793
-
-
Youn, H.D.1
Sun, L.2
Prywes, R.3
Liu, J.O.4
-
152
-
-
0034663805
-
Integration of calcineurin and MEF2 signals by the coactivator p300 during T-cell apoptosis
-
Youn HD, Chatila TA, Liu JO. 2000. Integration of calcineurin and MEF2 signals by the coactivator p300 during T-cell apoptosis. EMBO J 19:4323-4331.
-
(2000)
EMBO J
, vol.19
, pp. 4323-4331
-
-
Youn, H.D.1
Chatila, T.A.2
Liu, J.O.3
-
153
-
-
0036327656
-
Vitamin A and apoptosis in prostate cancer
-
Zhang XK. 2002. Vitamin A and apoptosis in prostate cancer. Endocr Relat Cancer 9:87-102.
-
(2002)
Endocr Relat Cancer
, vol.9
, pp. 87-102
-
-
Zhang, X.K.1
-
154
-
-
0033849372
-
Retinoids and ovarian cancer
-
Zhang D, Holmes WF, Wu S, Soprano DR, Soprano KJ. 2000. Retinoids and ovarian cancer. J Cell Physiol 185:1-20.
-
(2000)
J Cell Physiol
, vol.185
, pp. 1-20
-
-
Zhang, D.1
Holmes, W.F.2
Wu, S.3
Soprano, D.R.4
Soprano, K.J.5
-
155
-
-
0037108561
-
Induction of apoptosis of human B-CLL and ALL cells by a novel retinoid and its nonretinoidal analog
-
Zhang Y, Dawson MI, Mohammad R, Rishi AK, Farhana L, Feng KC, Leid M, Peterson V, Zhang XK, Edelstein M, Eilander D, Biggar S, Wall N, Reichert U, Fontana JA. 2002. Induction of apoptosis of human B-CLL and ALL cells by a novel retinoid and its nonretinoidal analog. Blood 100:2917-2925.
-
(2002)
Blood
, vol.100
, pp. 2917-2925
-
-
Zhang, Y.1
Dawson, M.I.2
Mohammad, R.3
Rishi, A.K.4
Farhana, L.5
Feng, K.C.6
Leid, M.7
Peterson, V.8
Zhang, X.K.9
Edelstein, M.10
Eilander, D.11
Biggar, S.12
Wall, N.13
Reichert, U.14
Fontana, J.A.15
-
156
-
-
0032953307
-
Regulation of the MEF2 family of transcription factors by p38
-
Zhao M, New L, Kravchenko VV, Kato Y, Gram H, di Padova F, Olson EN, Ulevitch RJ, Han J. 1999a. Regulation of the MEF2 family of transcription factors by p38. Mol Cell Biol 19:21-30.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 21-30
-
-
Zhao, M.1
New, L.2
Kravchenko, V.V.3
Kato, Y.4
Gram, H.5
Di Padova, F.6
Olson, E.N.7
Ulevitch, R.J.8
Han, J.9
-
157
-
-
0032950961
-
Mitochondrial and intracellular free-calcium regulation of radiation-induced apoptosis in human leukemic cells
-
Zhao QL, Kondo T, Noda A, Fujiwara Y. 1999b. Mitochondrial and intracellular free-calcium regulation of radiation-induced apoptosis in human leukemic cells. Int J Radiat Biol 75:493-504.
-
(1999)
Int J Radiat Biol
, vol.75
, pp. 493-504
-
-
Zhao, Q.L.1
Kondo, T.2
Noda, A.3
Fujiwara, Y.4
-
158
-
-
0012916665
-
Signal transduction in TNF-alpha-induced c-jun gene expression
-
Zhao M, Liu YW, Liu AH, Zhao KS, Jiang Y. 2000a. Signal transduction in TNF-alpha-induced c-jun gene expression. Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao 32:258-264.
-
(2000)
Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao
, vol.32
, pp. 258-264
-
-
Zhao, M.1
Liu, Y.W.2
Liu, A.H.3
Zhao, K.S.4
Jiang, Y.5
-
159
-
-
0034656243
-
Analysis of p53-regulated gene expression patterns using oligonucleotide arrays
-
Zhao R, Gish K, Murphy M, Yin Y, Notterman D, Hoffman WH, Tom E, Mack DH, Levine AJ. 2000b. Analysis of p53-regulated gene expression patterns using oligonucleotide arrays. Genes Dev 14:981-993.
-
(2000)
Genes Dev
, vol.14
, pp. 981-993
-
-
Zhao, R.1
Gish, K.2
Murphy, M.3
Yin, Y.4
Notterman, D.5
Hoffman, W.H.6
Tom, E.7
Mack, D.H.8
Levine, A.J.9
-
160
-
-
0030970351
-
Activation of pro-caspase-7 by serine proteases includes a non-canonical specificity
-
Zhou Q, Salvesen GS. 1997. Activation of pro-caspase-7 by serine proteases includes a non-canonical specificity. Biochem J 324:361-364.
-
(1997)
Biochem J
, vol.324
, pp. 361-364
-
-
Zhou, Q.1
Salvesen, G.S.2
-
161
-
-
0033613210
-
Solution structure of Apaf-1 CARD and its interaction with caspase-9 CARD: A structural basis for specific adaptor/caspase interaction
-
Zhou P, Chou J, Olea RS, Yuan J, Wagner G. 1999. Solution structure of Apaf-1 CARD and its interaction with caspase-9 CARD: A structural basis for specific adaptor/caspase interaction. Proc Natl Acad Sci USA 96:11265-11270.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 11265-11270
-
-
Zhou, P.1
Chou, J.2
Olea, R.S.3
Yuan, J.4
Wagner, G.5
-
162
-
-
0034714334
-
p38 mitogen-activated protein kinase mediates bid cleavage, mitochondrial dysfunction, and caspase-3 activation during apoptosis induced by singlet oxygen but not by hydrogen peroxide
-
Zhuang S, Demirs JT, Kochevar IE. 2000. p38 mitogen-activated protein kinase mediates bid cleavage, mitochondrial dysfunction, and caspase-3 activation during apoptosis induced by singlet oxygen but not by hydrogen peroxide. J Biol Chem 275:25939-25948.
-
(2000)
J Biol Chem
, vol.275
, pp. 25939-25948
-
-
Zhuang, S.1
Demirs, J.T.2
Kochevar, I.E.3
-
163
-
-
0033486001
-
Immune (dys)regulation in multiple sclerosis: Role of the CD95-CD95 ligand system
-
Zipp F, Krammer PH, Weller M. 1999. Immune (dys)regulation in multiple sclerosis: Role of the CD95-CD95 ligand system. Immunol Today 20:550-554.
-
(1999)
Immunol Today
, vol.20
, pp. 550-554
-
-
Zipp, F.1
Krammer, P.H.2
Weller, M.3
|