Bcl-2 targeted to the endoplasmic reticulum can inhibit apoptosis induced by Myc but not etoposide in Rat-1 fibroblasts

Oncogene

Volumn 18, Issue 23, 1999, Pages 3520-3528

  Lee, Si Tuen ^a   Hoeflich, Klaus P ^a   Wasfy, Gihane W ^a   Woodgett, James R ^a   Leber, Brian ^b   Andrews, David W ^b   Hedley, David W ^a   Penn, Linda Z ^a  

^a PRINCESS MARGARET HOSPITAL   (Canada)

^b MCMASTER UNIVERSITY   (Canada)

Author keywords

Apoptosis; Bcl 2; Etoposide; Membrane potential; Mitochondrial; Myc

Indexed keywords

CALCIUM ION; ETOPOSIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BCL 2;

ANIMAL CELL; APOPTOSIS; ARTICLE; CALCIUM CELL LEVEL; CELL NUCLEUS MEMBRANE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; FIBROBLAST CULTURE; MITOCHONDRIAL MEMBRANE; NONHUMAN; ONCOGENE MYC; PRIORITY JOURNAL; PROTO ONCOGENE; RAT;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CALCIUM; CASPASES; CELL LINE; ENDOPLASMIC RETICULUM; ENZYME ACTIVATION; ETOPOSIDE; INTRACELLULAR MEMBRANES; MEMBRANE POTENTIALS; MITOCHONDRIA; NUCLEIC ACID SYNTHESIS INHIBITORS; PROTO-ONCOGENE PROTEINS C-BCL-2; PROTO-ONCOGENE PROTEINS C-MYC; RATS;

ANIMALIA;

EID: 0033542461     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1202716     Document Type: Article

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