Single-dose ebselen does not afford sustained neuroprotection to rats subjected to severe focal cerebral ischemia

European Journal of Pharmacology

Volumn 495, Issue 1, 2004, Pages 55-62

  Salom, Juan B ^a,b   Pérez Asensio, Fernando J ^a   Burguete, María C ^a   Marín, Nuria ^b   Pitarch, Carlos ^b   Torregrosa, Germán ^a,b   Romero, Francisco J ^a,c   Alborch, Enrique ^a,b  

^a HOSPITAL UNIVERSITARIO LA FE   (Spain)

^b UNIVERSITY OF VALENCIA   (Spain)

^c UNIVERSIDAD CEU CARDENAL HERRERA   (Spain)

Author keywords

(Rat); Cerebral infarct; Ebselen; Focal ischemia; Oxidative stress

Indexed keywords

EBSELEN; GLUTATHIONE; SELENIUM;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD LEVEL; BRAIN INFARCTION; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; BRAIN LEVEL; BRAIN PERFUSION; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; MALE; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT;

ADMINISTRATION, ORAL; ANIMALS; AZOLES; BODY WEIGHT; BRAIN; BRAIN CHEMISTRY; BRAIN ISCHEMIA; DRUG ADMINISTRATION SCHEDULE; DRUG EVALUATION, PRECLINICAL; GLUTATHIONE; INFARCTION, MIDDLE CEREBRAL ARTERY; MALE; ORGANOSELENIUM COMPOUNDS; OXIDATIVE STRESS; RATS; RATS, WISTAR; REACTIVE OXYGEN SPECIES; REPERFUSION; SELENIUM; SPAIN; TIME FACTORS;

EID: 3042621435     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2004.05.024     Document Type: Article

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