Neuroprotective efficacy of ebselen, an anti-oxidant with anti-inflammatory actions, in a rodent model of permanent middle cerebral artery occlusion

British Journal of Pharmacology

Volumn 122, Issue 6, 1997, Pages 1251-1256

  Takasago, T ^a,d   Peters, E E ^a   Graham, D I ^b   Masayasu, H ^c   Macrae, I M ^a  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

^b SOUTHERN GENERAL HOSPITAL   (United Kingdom)

^c DAIICHI SANKYO CO   (Japan)

^d YAMAGUCHI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Anti oxidant; Ebselen; Focal cerebral ischaemia; Free radicals; Glutathione peroxidase mimic; Neuroprotection

Indexed keywords

ANTIOXIDANT; EBSELEN; NONSTEROID ANTIINFLAMMATORY AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BRAIN CORTEX; BRAIN INFARCTION; CAUDATE NUCLEUS; CONTROLLED STUDY; HISTOPATHOLOGY; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; NEUROPROTECTION; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RAT;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ANTIOXIDANTS; AZOLES; BRAIN ISCHEMIA; DISEASE MODELS, ANIMAL; MALE; NEUROPROTECTIVE AGENTS; ORGANOSELENIUM COMPOUNDS; RATS; RATS, INBRED F344;

EID: 0030734080     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0701426     Document Type: Article

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