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Volumn 27, Issue 9, 1996, Pages 1453-1458

A randomized trial of tirilazad mesylate in patients with acute stroke (RANTTAS)

Author keywords

cerebral ischemia; lipid peroxidation; neuroprotection; stroke, acute

Indexed keywords

TIRILAZAD;

EID: 0043204506     PISSN: 00392499     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.STR.27.9.1453     Document Type: Article
Times cited : (218)

References (20)
  • 1
    • 0001863422 scopus 로고
    • Epidemiology of stroke
    • Barnett HJ, Mohr JP, Stein BM, Yatsu FM, eds. New York, NY: Churchill Livingstone Inc
    • Wolf PA, Cobb JL, D'Agostino RB. Epidemiology of stroke. In: Barnett HJ, Mohr JP, Stein BM, Yatsu FM, eds. Stroke Pathophysiology, Diagnosis, and Management. New York, NY: Churchill Livingstone Inc; 1992:3-27.
    • (1992) Stroke Pathophysiology, Diagnosis, and Management , pp. 3-27
    • Wolf, P.A.1    Cobb, J.L.2    D'Agostino, R.B.3
  • 2
    • 0020703133 scopus 로고
    • Current status of risk factors for stroke
    • Wolf PA, Kannel WB, Verter J. Current status of risk factors for stroke. Neurol Clin. 1983;1:317-343.
    • (1983) Neurol Clin , vol.1 , pp. 317-343
    • Wolf, P.A.1    Kannel, W.B.2    Verter, J.3
  • 3
    • 0024520513 scopus 로고
    • Central nervous system trauma and stroke, I: Biochemical considerations for oxygen radical formation and lipid peroxidation
    • Braughler JM, Hall ED. Central nervous system trauma and stroke, I: biochemical considerations for oxygen radical formation and lipid peroxidation. Free Radic Biol Med. 1989;6:289-301.
    • (1989) Free Radic Biol Med , vol.6 , pp. 289-301
    • Braughler, J.M.1    Hall, E.D.2
  • 4
    • 0024589421 scopus 로고
    • Central nervous system trauma and stroke, II: Physiological and pharmacological evidence for involvement of oxygen radicals and lipid peroxidation
    • Hall ED, Braughler JM. Central nervous system trauma and stroke, II: physiological and pharmacological evidence for involvement of oxygen radicals and lipid peroxidation. Free Radic Biol Med. 1989; 6:303-313.
    • (1989) Free Radic Biol Med , vol.6 , pp. 303-313
    • Hall, E.D.1    Braughler, J.M.2
  • 5
    • 0028187682 scopus 로고
    • Therapeutic potential of the lazaroids (21-aminosteroids) in acute central nervous system trauma, ischemia and subarachnoid hemorrhage
    • Hall ED, McCall JM, Means ED. Therapeutic potential of the lazaroids (21-aminosteroids) in acute central nervous system trauma, ischemia and subarachnoid hemorrhage. Adv Pharmacol. 1994;28: 221-267.
    • (1994) Adv Pharmacol , vol.28 , pp. 221-267
    • Hall, E.D.1    McCall, J.M.2    Means, E.D.3
  • 6
    • 0001652669 scopus 로고
    • U-74006F, an inhibitor of lipid peroxidalion, protects against lesion development following experimental stroke in the cat: Histologic and metabolic analysis
    • Abstract
    • Silvia RC, Piercey MF, Hoffman WE, Chase RL, Tang AH, Brughler JM. U-74006F, an inhibitor of lipid peroxidalion, protects against lesion development following experimental stroke in the cat: histologic and metabolic analysis. Soc Neurosci Symp. 1987;13:1499. Abstract.
    • (1987) Soc Neurosci Symp , vol.13 , pp. 1499
    • Silvia, R.C.1    Piercey, M.F.2    Hoffman, W.E.3    Chase, R.L.4    Tang, A.H.5    Brughler, J.M.6
  • 7
    • 0023772124 scopus 로고
    • Aminosteroid lipid peroxidation inhibitor reduces ion shifts and edema in the rat middle cerebral artery occlusion model of regional ischemia
    • Young W, Wofak JC, Decrescito V. Aminosteroid lipid peroxidation inhibitor reduces ion shifts and edema in the rat middle cerebral artery occlusion model of regional ischemia. Stroke. 1988;19:1013-1019.
    • (1988) Stroke , vol.19 , pp. 1013-1019
    • Young, W.1    Wofak, J.C.2    Decrescito, V.3
  • 8
    • 0001242278 scopus 로고
    • Effect of U74006F on oedema and infarct volumes following permanent occlusion of the middle cerebral artery in the rat
    • Abstract
    • Lythgoe W, Little RA, O'Shaughnessy CT, Steward MC. Effect of U74006F on oedema and infarct volumes following permanent occlusion of the middle cerebral artery in the rat. Br J Pharmacol. 1990;100:454P. Abstract.
    • (1990) Br J Pharmacol , vol.100
    • Lythgoe, W.1    Little, R.A.2    O'Shaughnessy, C.T.3    Steward, M.C.4
  • 9
    • 0002404119 scopus 로고
    • Effect of tirilazad mesylate on middle cerebral artery occlusion/reperfusion in nonhuman primates
    • Mori E, Ember J, Copeland BR, Thomas WS, Koziol JA, del Zoppo GJ. Effect of tirilazad mesylate on middle cerebral artery occlusion/reperfusion in nonhuman primates. Cerebrovasc Dis. 1995;5:342-349.
    • (1995) Cerebrovasc Dis , vol.5 , pp. 342-349
    • Mori, E.1    Ember, J.2    Copeland, B.R.3    Thomas, W.S.4    Koziol, J.A.5    Del Zoppo, G.J.6
  • 10
    • 0027419603 scopus 로고
    • Evaluation of the pharmacokinetics and tolerability of tirilazad mesylate, a 21-aminosteroid free radical scavenger, I: Single-dose administration
    • Fleishaker JC, Peters GR, Cathcart KS. Evaluation of the pharmacokinetics and tolerability of tirilazad mesylate, a 21-aminosteroid free radical scavenger, I: single-dose administration. J Clin Pharmacol. 1993;33:175-181.
    • (1993) J Clin Pharmacol , vol.33 , pp. 175-181
    • Fleishaker, J.C.1    Peters, G.R.2    Cathcart, K.S.3
  • 11
    • 0027418840 scopus 로고
    • Evaluation of the pharmacokinetics and tolerability of tirilazad mesylate, a 21-aminosteroid free radical scavenger, II: Multiple-dose administration
    • Fleishaker JC, Peters GR, Cathcart KS, Steenwyk RC. Evaluation of the pharmacokinetics and tolerability of tirilazad mesylate, a 21-aminosteroid free radical scavenger, II: multiple-dose administration. J Clin Pharmacol. 1993;33:182-190.
    • (1993) J Clin Pharmacol , vol.33 , pp. 182-190
    • Fleishaker, J.C.1    Peters, G.R.2    Cathcart, K.S.3    Steenwyk, R.C.4
  • 12
    • 0028036213 scopus 로고
    • Safety study of tirilazad mesylate in patients with acute ischemic stroke (STIPAS)
    • STIPAS Investigators. Safety study of tirilazad mesylate in patients with acute ischemic stroke (STIPAS). Stroke. 1994;25:418-423.
    • (1994) Stroke , vol.25 , pp. 418-423
  • 13
    • 70450195021 scopus 로고
    • Functional evaluation: Barthel Index
    • Mahoney FT, Barthel DW. Functional evaluation: Barthel Index. Md Med J. 1965;14:61-65.
    • (1965) Md Med J , vol.14 , pp. 61-65
    • Mahoney, F.T.1    Barthel, D.W.2
  • 14
    • 0016475167 scopus 로고
    • Assessment of outcome after severe brain damage: A practical scale
    • Jennett B, Bond M. Assessment of outcome after severe brain damage: a practical scale. Lancet. 1975;1:480-484.
    • (1975) Lancet , vol.1 , pp. 480-484
    • Jennett, B.1    Bond, M.2
  • 17
    • 0027514354 scopus 로고
    • Classification of subtype of acute ischemic stroke: Definitions for use in a multicenter clinical trial, TOAST: Trial of Org 10172 in Acute Stroke Treatment
    • Adams HP Jr, Bendixen BH, Kappelle LJ, Biller J, Love BB, Gordon DL, Marsh EE III. Classification of subtype of acute ischemic stroke: definitions for use in a multicenter clinical trial, TOAST: Trial of Org 10172 in Acute Stroke Treatment. Stroke. 1993;24:35-41.
    • (1993) Stroke , vol.24 , pp. 35-41
    • Adams Jr., H.P.1    Bendixen, B.H.2    Kappelle, L.J.3    Biller, J.4    Love, B.B.5    Gordon, D.L.6    Marsh III, E.E.7
  • 18
    • 0022395309 scopus 로고
    • Early decision in clinical trials when the treatment differences are small: Experience of a controlled trial in head trauma
    • Choi SC, Smith PJ, Becker DP. Early decision in clinical trials when the treatment differences are small: experience of a controlled trial in head trauma. Control Clin Trials. 1985;6:280-288.
    • (1985) Control Clin Trials , vol.6 , pp. 280-288
    • Choi, S.C.1    Smith, P.J.2    Becker, D.P.3
  • 19
    • 0018687930 scopus 로고
    • A multiple testing procedure for clinical trials
    • O'Brien PC, Fleming TR. A multiple testing procedure for clinical trials. Biometrics. 1979;35:549-556.
    • (1979) Biometrics , vol.35 , pp. 549-556
    • O'Brien, P.C.1    Fleming, T.R.2
  • 20
    • 0003783489 scopus 로고
    • Programs for computing group sequential bounds using the Lan-DeMets method
    • Washington, DC: George Washington University; June 22
    • Reboussin DM, DeMets DL, Kim K, Lan KKG. Programs for computing group sequential bounds using the Lan-DeMets method. Biostatistics Technical Report No. 60. Washington, DC: George Washington University; June 22, 1992.
    • (1992) Biostatistics Technical Report No. 60
    • Reboussin, D.M.1    DeMets, D.L.2    Kim, K.3    Lan, K.K.G.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.