Nitrotyrosine generation via inducible nitric oxide synthase in vascular wall in focal ischemia-reperfusion

Brain Research

Volumn 852, Issue 2, 2000, Pages 319-325

  Hirabayashi, Hisayuki ^a   Takizawa, Shunya ^a   Fukuyama, Naoto ^a   Nakazawa, Hiroe ^a   Shinohara, Yukito ^a  

^a TOKAI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Brain ischemia; Endothelium; Nitric oxide; Peroxynitrite; Transgenic mice

Indexed keywords

3 NITROTYROSINE; NITRIC OXIDE SYNTHASE; PEROXYNITRITE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL WALL; BRAIN BLOOD FLOW; BRAIN ISCHEMIA; CONTROLLED STUDY; IMMUNOHISTOCHEMISTRY; KNOCKOUT MOUSE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; REPERFUSION; TRANSGENIC MOUSE; VASCULAR ENDOTHELIUM;

ACIDOSIS; ANIMALS; BLOOD GLUCOSE; BLOOD PRESSURE; CARBON DIOXIDE; CEREBRAL CORTEX; CEREBROVASCULAR CIRCULATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; ENDOTHELIUM, VASCULAR; INFARCTION, MIDDLE CEREBRAL ARTERY; ISCHEMIC ATTACK, TRANSIENT; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NITRATES; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; OXYGEN; REPERFUSION INJURY; TYROSINE;

EID: 0033985973     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(99)02117-4     Document Type: Article

References (27)

1. Barone F.C., Knudsen D.J., Nelson A.H., Feuerstein G.Z., Willette R.N. Mouse strain differences in susceptibility to cerebral ischemia are related to cerebral vascular anatomy. J. Cereb. Blood Flow Metab. 13:1993;683-692.
2. Beckman J.S. Peroxynitrite versus hydroxyl radical: the role of nitric oxide in superoxide-dependent cerebral injury. Ann. N. Y. Acad. Sci. 738:1994;69-75.
3. Beckman J.S., Carson M., Smith C.D., Koppenol W.H. ALS, SOD and peroxynitrite. Nature. 364:1993;584.
4. Beckman J.S., Ye Y.Z., Anderson P.G., Chen J., Accavitti M.A., Tarpey M.M., White C.R. Extensive nitration of protein tyrosines in human atherosclerosis detected by immunohistochemistry. Biol. Chem. 375:1994;81-88.
5. Bidmon H.J., Wu J., Buchkremer-ratzmann I., Mayer B., Witte O.W., Zilles K. Transient changes in the presence of nitric oxide synthases and nitrotyrosine immunoreactivity after focal cortical lesions. Neuroscience. 82:1998;377-395.
6. Eiserich J.P., Hristova M., Cross C.E., Jones A.D., Freeman B.A., Halliwell B., van der Vliet A. Formation of nitric oxide-derived inflammatory oxidants by myeloperoxidase in neutrophiles. Nature. 391:1998;393-397.
7. Forster C., Clark H.B., Ross M.E., Iadecola C. Inducible nitric oxide synthase expression in human cerebral infarcts. Acta Neuropathol. 97:1999;215-220.
8. Fukuyama N., Takizawa S., Ishida H., Hoshiai K., Shinohara Y., Nakazawa H. Peroxynitrite formation in focal cerebral ischemia-reperfusion in rats occurs predominantly in the peri-infarct region. J. Cereb. Blood Flow Metab. 18:1998;123-129.
9. Grandati M., Verrecchia C., Revaud M.L., Allix M., Boulu R.G., Plotkine M. Calcium-independent NO-synthase activity and nitrites/nitrates production in transient focal cerebral ischemia in mice. Br. J. Pharmacol. 122:1997;625-630.
10. Hara H., Huang P.L., Panahian N., Fishman M.C., Moskowitz M.A. Reduced brain edema and infarction volume in mice lacking the neuronal isoform of nitric oxide synthase after transient MCA occlusion. J. Cereb. Blood Flow Metab. 16:1996;605-611.
11. Huang P.L., Dawson T.M., Bredt D.S., Snyder S.H., Fishman M.C. Targeted disruption of the neuronal nitric oxide synthase gene. Cell. 75:1993;1273-1286.
12. Iadecola C., Zhang F., Casey R., Clark H.B., Ross M.E. Inducible nitric oxide synthase gene expression in vascular cells after transient focal cerebral ischemia. Stroke. 27:1996;1373-1380.
13. Iadecola C., Zhang F., Casey R., Nagayama M., Ross M.E. Delayed reduction of ischemic brain injury and neurological deficits in mice lacking the inducible nitric oxide synthase gene. J. Neurosci. 17(23):1997;9157-9164.
14. Iadecola C., Zhang F., Xu X. Inhibition of inducible nitric oxide synthase ameliorates cerebral ischemic damage. Am. J. Physiol. 268:1995;R286-R292.
15. Iadecola C., Zhang F., Xu S., Casey R., Ross M.E. Inducible nitric oxide synthase gene expression in brain following cerebral ischemia. J. Cereb. Blood Flow Metab. 15:1995;378-384.
16. Ischiropoulos H. Biological tyrosine nitration: a pathophysiological function of nitric oxide and reactive oxygen species. Arch. Biochem. Biophys. 356:1998;1-11.
17. Kato H., Kogure K., Liu X.H., Araki T., Itoyama Y. Progressive expression of immunomolecules on activated microglia and invading leukocytes following focal cerebral ischemia in the rat. Brain Res. 734:1996;203-212.
18. Katusic Z.S. Superoxide anion and endothelial regulation of arterial tone. Free Radic. Biol. Med. 20:1996;443-448.
19. Kaur H., Lyras L., Jenner P., Halliwell B. Artefacts in HPLC detection of 3-nitrotyrosine in human brain tissue. J. Neurochem. 70:1998;2220-2223.
20. Laszlo F., Evans S.M., Whittle B.J.R. Aminoguanidine inhibits both constitutive and inducible nitric oxide synthase isoforms in rat intestinal microvasculature in vivo. Eur. J. Pharmacol. 272:1995;169-175.
21. MacMicking J.D., Nathan C., Hom G., Chartrain N., Fletcher D.S., Trumbauer M., Stevens K., Xie Q.W., Sokol K., Hutchinson N., Chen H., Mudgett J.S. Altered responses to bacterial infection and endotoxic shock in mice lacking inducible nitric oxide synthase. Cell. 81:1995;641-650.
22. Matsuo Y., Kihara T., Ikeda M., Ninomiya M., Onodera H., Kogure K. Role of neutrophils in radical production during ischemia and reperfusion of the rat brain: effect of neutrophil depletion on extracellular ascorbyl radical formation. J. Cereb. Blood Flow Metab. 15:1995;941-947.
23. Phillis J.W., Sen S. Oxypurinol attenuates hydroxyl radical production during ischemia/reperfusion injury of the rat cerebral cortex: an ESR study. Brain Res. 628:1993;309-312.
24. Samdani A.F., Dawson T.M., Dawson V.L. Nitric oxide synthase in models of focal ischemia. Stroke. 28:1997;1283-1288.
25. Schinetti M.L., Sbarbati R., Scarlattini M. Superoxide production by human umbilical vein endothelial cells in an anoxia-reoxygenation model. Cardiovasc. Res. 23:1989;76-80.
26. Shigenaga M.K., Lee H.H., Blount B.C., Christen S., Shigeno E.T., Yip H., Ames B.N. Inflammation and NOx-induced nitration: assay for 3-nitrotyrosine by HPLC with electrochemical detection. Proc. Natl. Acad. Sci. U.S.A. 94:1997;3211-3216.
27. Takizawa S., Fukuyama N., Hirabayashi H., Nakazawa H., Shinohara Y. Dynamics of nitrotyrosine formation and decay in rat brain during focal ischemia-reperfusion. J. Cereb. Blood Flow Metab. 19:1999;667-672.