Relationship between hepatic phenotype and changes in gene expression in cytochrome P450 reductase (POR) null mice

Biochemical Journal

Volumn 388, Issue 3, 2005, Pages 857-867

  Wang, Xiu Jun ^a   Chamberlain, Mark ^a   Vassieva, Olga ^b   Henderson, Colin J ^a   Wolf, C Roland ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

^b CXR Biosciences Ltd   (United Kingdom)

Author keywords

Bile acid; Cholesterol and lipid metabolism; Cytochrome p450; Cytochrome p450 reductase; Microarray analysis

Indexed keywords

ALCOHOLS; BIOCHEMISTRY; CHARACTERIZATION; DRUG PRODUCTS; GENES; LIPIDS; METABOLISM; REAL TIME SYSTEMS; RNA;

ELECTRON DONOR; GLYCOLYSIS; LIPID TRANSPORT; MICROARRAY ANALYSIS; XENOBIOTIC COMPOUNDS;

ENZYMES;

11BETA HYDROXYSTEROID DEHYDROGENASE 1; 3BETA HYDROXY DELTA5 STEROID DEHYDROGENASE 5; BILE ACID; CHOLESTEROL 7ALPHA MONOOXYGENASE; CYTOCHROME P450 2B10; CYTOCHROME P450 2C29; CYTOCHROME P450 3A11; CYTOCHROME P450 3A16; CYTOCHROME P450 7B1; CYTOCHROME P450 8B1; CYTOCHROME P450 REDUCTASE; MESSENGER RNA; STEROID REDUCTASE; UNCLASSIFIED DRUG; XENOBIOTIC AGENT;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DNA MICROARRAY; ELECTRON TRANSPORT; ENZYME ACTIVITY; ESTRADIOL BLOOD LEVEL; GENE EXPRESSION; HOMEOSTASIS; LIVER; METABOLISM; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; STEROID METABOLISM; TESTOSTERONE BLOOD LEVEL;

ANIMALS; CARBOHYDRATE METABOLISM; CHOLESTEROL; CYTOSKELETON; GENE DELETION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GLYCOLYSIS; HORMONES; IMMUNITY; LIPID METABOLISM; LIVER; MICE; MICE, KNOCKOUT; NADPH-FERRIHEMOPROTEIN REDUCTASE; NEOPLASMS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; OXIDATIVE STRESS; PHENOTYPE; PHOSPHORYLATION; RNA, MESSENGER; SIGNAL TRANSDUCTION;

EID: 21744456583     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20042087     Document Type: Article

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