Gene silencing in primary and metastatic tumors by small interfering RNA delivery in mice: Quantitative analysis using melanoma cells expressing firefly and sea pansy luciferases

Journal of Controlled Release

Volumn 105, Issue 3, 2005, Pages 332-343

  Takahashi, Yuki ^a   Nishikawa, Makiya ^a   Kobayashi, Naoki ^a   Takakura, Yoshinobu ^a  

^a NONE

Author keywords

Gene delivery; Hepatic tumor; Hydrodynamics based procedure; Luciferase; RNAi

Indexed keywords

CELL CULTURE; CELLS; GENES; HYDRODYNAMICS; PATIENT TREATMENT; RNA; TUMORS;

DIRECT INJECTION; ELECTROPORATION; GENE EXPRESSION; METASTATIC TUMORS;

DRUG THERAPY;

LUCIFERASE; PLASMID DNA; SMALL INTERFERING RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; ELECTROPORATION; GENE EXPRESSION; GENE REPRESSION; GENE SILENCING; GENE TARGETING; GENETIC TRANSFECTION; HYDRODYNAMICS; MALE; MELANOMA CELL; METASTASIS; MOUSE; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; RNA INTERFERENCE; STATISTICAL SIGNIFICANCE; TUMOR;

ANIMALS; CELL LINE, TUMOR; DNA, NEOPLASM; ELECTROPORATION; FIREFLIES; GENE SILENCING; LUCIFERASES; MALE; MELANOMA, EXPERIMENTAL; MICE; MICE, INBRED C57BL; MICROSCOPY, CONFOCAL; NEOPLASM METASTASIS; NEOPLASM TRANSPLANTATION; NEOPLASMS; RENILLA; RNA, MESSENGER; RNA, NEOPLASM; RNA, SMALL INTERFERING; TRANSGENES;

EID: 21744449616     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2005.04.012     Document Type: Article

References (39)

1. P.D. Zamore, T. Tuschl, P.A. Sharp, and D.P. Bartel RNAi: double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals Cell 101 2000 25 33
2. T. Tuschl, P.D. Zamore, R. Lehmann, D.P. Bartel, and P.A. Sharp Targeted mRNA degradation by double-stranded RNA in vitro Genes Dev. 13 1999 3191 3197
3. S.M. Hammond, E. Bernstein, D. Beach, and G.J. Hannon An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells Nature 404 2000 293 296
4. S.M. Elbashir, J. Harborth, W. Lendeckel, A. Yalcin, K. Weber, and T. Tuschl Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells Nature 411 2001 494 498
5. N.J. Caplen, S. Parrish, F. Imani, A. Fire, and R.A. Morgan Specific inhibition of gene expression by small double-stranded RNAs in invertebrate and vertebrate systems Proc. Natl. Acad. Sci. U. S. A. 98 2001 9742 9747 (Electronic publication 2001 Jul 31)
6. M.T. McManus, and P.A. Sharp Gene silencing in mammals by small interfering RNAs Nat. Rev. Genet. 3 2002 737 747
7. J. Zhang, and Z.C. Hua Targeted gene silencing by small interfering RNA-based knock-down technology Curr. Pharm. Biotechnol. 5 2004 1 7
8. O. Milhavet, D.S. Gary, and M.P. Mattson RNA interference in biology and medicine Pharmacol. Rev. 55 2003 629 648
9. J. Lieberman, E. Song, S.K. Lee, and P. Shankar Interfering with disease: opportunities and roadblocks to harnessing RNA interference Trends Mol. Med. 9 2003 397 403
10. U.N. Verma, R.M. Surabhi, A. Schmaltieg, C. Becerra, and R.B. Gaynor Small interfering RNAs directed against beta-catenin inhibit the in vitro and in vivo growth of colon cancer cells Clin. Cancer Res. 9 2003 1291 3000
11. S. Filleur, A. Courtin, S. Ait-Si-Ali, J. Guglielmi, C. Merle, A. Harel-Bellan, P. Clezardin, and F. Cabon SiRNA-mediated inhibition of vascular endothelial growth factor severely limits tumor resistance to antiangiogenic thrombospondin-1 and slows tumor vascularization and growth Cancer Res. 63 2003 3919 3922
12. Y. Zhang, R.J. Boado, and W.M. Pardridge In vivo knockdown of gene expression in brain cancer with intravenous RNAi in adult rats J. Gene Med. 5 2003 1039 1045
13. M.S. Duxbury, H. Ito, M.J. Zinner, S.W. Ashley, and E.E. Whang EphA2: a determinant of malignant cellular behavior and a potential therapeutic target in pancreatic adenocarcinoma Oncogene 23 2004 1448 1456
14. Y. Zeng, and B.R. Cullen RNA interference in human cells is restricted to the cytoplasm RNA 8 2002 855 860
15. P. Stein, P. Svoboda, M. Anger, and R.M. Schultz RNAi: mammalian oocytes do it without RNA-dependent RNA polymerase RNA 9 2003 187 192
16. M. Miyagishi, and K. Taira U6 promoter-driven siRNAs with four uridine 3′ overhangs efficiently suppress targeted gene expression in mammalian cells Nat. Biotechnol. 20 2002 497 500
17. T.R. Brummelkamp, R. Bernards, and R. Agami A system for stable expression of short interfering RNAs in mammalian cells Science 296 2002 550 553 (Electronic publication 2002 Mar 21)
18. H. Kawasaki, and K. Taira Short hairpin type of dsRNAs that are controlled by tRNA(Val) promoter significantly induce RNAi-mediated gene silencing in the cytoplasm of human cells Nucleic Acids Res. 31 2003 700 777
19. H. Xia, Q. Mao, H.L. Paulson, and B.L. Davidson siRNA-mediated gene silencing in vitro and in vivo Nat. Biotechnol. 20 2002 1006 1010
20. M. van de Wetering, I. Oving, V. Muncan, M.T. Pon Fong, H. Brantjes, D. van Leenen, F.C. Holstege, T.R. Brummelkamp, R. Agami, and H. Clevers Specific inhibition of gene expression using a stably integrated, inducible small-interfering-RNA vector EMBO Rep. 4 2003 609 615
21. N. Kobayashi, Y. Matsui, A. Kawase, K. Hirata, M. Miyagishi, K. Taira, M. Nishikawa, and Y. Takakura Vector-based in vivo RNA interference: dose-and time-dependent suppression of transgene expression J. Pharmacol. Exp. Ther. 308 2004 688 693 (Electronic publication 2003 Nov 10)
22. L. Zhang, K.E. Hellstrom, and L. Chen Luciferase activity as a marker of tumor burden and as an indicator of tumor response to antineoplastic therapy in vivo Clin. Exp. Metastasis. 12 1994 87 92
23. E.E. Nilsson, S.D. Westfall, C. McDonald, T. Lison, I. Sadler-Riggleman, and M.K. Skinner An in vivo mouse reporter gene (human secreted alkaline phosphatase) model to monitor ovarian tumor growth and response to therapeutics Cancer Chemother. Pharmacol. 49 2002 93 100 (Electronic publication 2001 Nov 23)
24. T. Nomura, K. Yasuda, T. Yamada, S. Okamoto, R.I. Mahato, Y. Watanabe, Y. Takakura, and M. Hashida Gene expression and antitumor effects following direct interferon (IFN)-gamma gene transfer with naked plasmid DNA and DC-chol liposome complexes in mice Gene Ther. 6 1999 121 129
25. N. Kobayashi, M. Nishikawa, K. Hirata, and Y. Takakura Hydrodynamics-based procedure involves transient hyperpermeability in the hepatic cellular membrane: implication of a nonspecific process in efficient intracellular gene delivery J. Gene Med. 6 2004 584 592
26. G. Poste, J. Doll, I.R. Hart, and I.J. Fidler In vitro selection of murine B16 melanoma variants with enhanced tissue-invasive properties Cancer Res. 40 1980 1636 1644
27. K. Hyoudou, M. Nishikawa, Y. Umeyama, Y. Kobayashi, F. Yamashita, and M. Hashida Inhibition of metastatic tumor growth in mouse lung by repeated administration of polyethylene glycol-conjugated catalase: quantitative analysis using firefly luciferase-expressing melanoma cells Clin. Cancer Res. 10 2004 7685 7691
28. R.J. Mumper, J.G. Duguid, K. Anwer, M.K. Barron, H. Nitta, and A.P. Rolland Polyvinyl derivatives as novel interactive polymers for controlled gene delivery to muscle Pharm. Res. 13 1996 701 709
29. H. Alila, M. Coleman, H. Nitta, M. French, K. Anwer, Q. Liu, T. Meyer, J. Wang, R. Mumper, D. Oubari, S. Long, J. Nordstrom, and A. Rolland Expression of biologically active human insulin-like growth factor-I following intramuscular injection of a formulated plasmid in rats Hum. Gene Ther. 8 1997 1785 1795
30. C. Mennuni, F. Calvaruso, I. Zampaglione, G. Rizzuto, D. Rinaudo, E. Dammassa, G. Ciliberto, E. Fattori, and N. La Monica Hyaluronidase increases electrogene transfer efficiency in skeletal muscle Hum. Gene Ther. 13 2002 355 365
31. J.M. McMahon, E. Signori, K.E. Wells, V.M. Fazio, and D.J. Wells Optimisation of electrotransfer of plasmid into skeletal muscle by pretreatment with hyaluronidase-increased expression with reduced muscle damage Gene Ther. 8 2001 1264 1270
32. F. Liu, Y. Song, and D. Liu Hydrodynamics-based transfection in animals by systemic administration of plasmid DNA Gene Ther. 6 1999 1258 1266
33. T.A. Vickers, S. Koo, C.F. Bennett, S.T. Crooke, N.M. Dean, and B.F. Baker Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents. A comparative analysis J. Biol. Chem. 278 2003 7108 7118 (Electronic publication 2002 Dec 23)
34. K. Yoshinari, M. Miyagishi, and K. Taira Effects on RNAi of the tight structure, sequence and position of the targeted region Nucleic Acids Res. 32 2004 691 699 (Print 2004)
35. A. Reynolds, D. Leake, Q. Boese, S. Scaringe, W.S. Marshall, and A. Khvorova Rational siRNA design for RNA interference Nat. Biotechnol. 22 2004 326 330 (Electronic publication 2004 Feb 1)
36. J.M. Silva, R. Sachidanandam, and G.J. Hannon Free energy lights the path toward more effective RNAi Nat. Genet. 35 2003 303 335
37. H. Herweijer, and J.A. Wolff Progress and prospects: naked DNA gene transfer and therapy Gene Ther. 10 2003 453 458
38. M. Nishikawa, and L. Huang Nonviral vectors in the new millennium: delivery barriers in gene transfer Hum. Gene Ther. 12 2001 861 870
39. R. Engers, and H.E. Gabbert Mechanisms of tumor metastasis: cell biological aspects and clinical implications J. Cancer Res. Clin. Oncol. 126 2000 682 692