Vector-Based in Vivo RNA Interference: Dose- and Time-Dependent Suppression of Transgene Expression

Journal of Pharmacology and Experimental Therapeutics

Volumn 308, Issue 2, 2004, Pages 688-693

  Kobayashi, Naoki ^a   Matsui, Yumi ^a   Kawase, Atsushi ^a   Hirata, Kazuhiro ^d   Miyagishi, Makoto ^b,c   Taira, Kazunari ^b,c   Nishikawa, Makiya ^a   Takakura, Yoshinobu ^a  

^a KYOTO UNIVERSITY   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

^d NONE

Author keywords

[No Author keywords available]

Indexed keywords

EXORIBONUCLEASE; LUCIFERASE; PLASMID DNA; SMALL INTERFERING RNA; U6 NUCLEASE;

ANIMAL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELLULAR DISTRIBUTION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; FEMALE; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENE SILENCING; GENE TARGETING; GENE VECTOR; GENETIC CODE; GENETICS; HUMAN; HYDRODYNAMICS; IN VIVO STUDY; INJECTION; KIDNEY; LIVER; LUNG; MOUSE; MUSCLE; NONHUMAN; PHYSIOLOGY; PLASMID; PRIORITY JOURNAL; REPORTER GENE; RNA INTERFERENCE; RNA VECTOR; SOMATIC CELL GENETICS; TIME; TRANSGENE;

ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; EXORIBONUCLEASES; GENE EXPRESSION; GENE SILENCING; GENES, REPORTER; GENETIC VECTORS; HUMANS; MICE; PLASMIDS; RNA INTERFERENCE; RNA, SMALL INTERFERING; TIME FACTORS; TRANSGENES;

EID: 1642538990     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: 10.1124/jpet.103.059931     Document Type: Article

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