메뉴 건너뛰기




Volumn 3, Issue 12, 1997, Pages 852-863

Transcription abnormalities potentiate apoptosis of normal human fibroblasts

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA AMANITIN; CISPLATIN; DACTINOMYCIN; DNA FRAGMENT; MITOMYCIN C; PROTEIN P21; PROTEIN P53; RNA POLYMERASE II INHIBITOR; UNCLASSIFIED DRUG;

EID: 0031416213     PISSN: 10761551     EISSN: None     Source Type: Journal    
DOI: 10.1007/bf03401721     Document Type: Article
Times cited : (56)

References (74)
  • 1
    • 0029670589 scopus 로고    scopus 로고
    • p53 in signaling checkpoint arrest or apoptosis
    • Bates S, Vousden KH. (1996) p53 in signaling checkpoint arrest or apoptosis. Curr. Opin. Genet. Dev. 6: 12-18.
    • (1996) Curr. Opin. Genet. Dev. , vol.6 , pp. 12-18
    • Bates, S.1    Vousden, K.H.2
  • 2
    • 0029980043 scopus 로고    scopus 로고
    • p53 in growth control and neoplasia
    • Gottlieb TM, Oren M. (1996) p53 in growth control and neoplasia. Biochim. Biophys. Acta 1287: 77-102.
    • (1996) Biochim. Biophys. Acta , vol.1287 , pp. 77-102
    • Gottlieb, T.M.1    Oren, M.2
  • 3
    • 0029972806 scopus 로고    scopus 로고
    • p53: Puzzle and paradigm
    • Ko LJ, Prives C. (1996) p53: puzzle and paradigm. Genes Dev. 10: 1054-1072.
    • (1996) Genes Dev. , vol.10 , pp. 1054-1072
    • Ko, L.J.1    Prives, C.2
  • 4
    • 0030941458 scopus 로고    scopus 로고
    • p53, the cellular gate-keeper for growth and division
    • Levine AJ. (1997) p53, the cellular gate-keeper for growth and division. Cell 88: 323-331.
    • (1997) Cell , vol.88 , pp. 323-331
    • Levine, A.J.1
  • 5
    • 0031051042 scopus 로고    scopus 로고
    • p53; from inductive signal to cellular effect
    • Hansen R, Oren M. (1997) p53; from inductive signal to cellular effect. Curr. Opin. Genet. Dev. 7: 46-51.
    • (1997) Curr. Opin. Genet. Dev. , vol.7 , pp. 46-51
    • Hansen, R.1    Oren, M.2
  • 7
    • 0027262606 scopus 로고
    • Stabilization of the p53 tumor suppressor is induced by adenovirus 5 E1A and accompanies apoptosis
    • Lowe SW, Ruley HE. (1993) Stabilization of the p53 tumor suppressor is induced by adenovirus 5 E1A and accompanies apoptosis. Genes Dev. 7: 535-545.
    • (1993) Genes Dev. , vol.7 , pp. 535-545
    • Lowe, S.W.1    Ruley, H.E.2
  • 8
    • 0027332996 scopus 로고
    • Differential induction of transcriptionally active p53 following UV or ionizing radiation: Defects in chromosome instability syndromes?
    • Lu X, Lane DP. (1993) Differential induction of transcriptionally active p53 following UV or ionizing radiation: Defects in chromosome instability syndromes? Cell 75: 765-778.
    • (1993) Cell , vol.75 , pp. 765-778
    • Lu, X.1    Lane, D.P.2
  • 9
    • 0027298576 scopus 로고
    • Induction of cellular p53 activity by DNA-damaging agents and growth arrest
    • erratum appears in Mol. Cell. Biol. (1993) 13(9): 5928
    • Zhan Q, Carrier F, Fornace AJ, Jr. (1993) Induction of cellular p53 activity by DNA-damaging agents and growth arrest [erratum appears in Mol. Cell. Biol. (1993) 13(9): 5928]. Mol. Cell. Biol. 13: 4242-4250.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 4242-4250
    • Zhan, Q.1    Carrier, F.2    Fornace Jr., A.J.3
  • 10
    • 0028325483 scopus 로고
    • Growth arrest by induction of p53 in DNA damaged keratinocytes is bypassed by human papillomavirus 16 E7
    • Demers GW, Foster SA, Halbert CL, Galloway DA. (1994) Growth arrest by induction of p53 in DNA damaged keratinocytes is bypassed by human papillomavirus 16 E7. Proc. Natl. Acad. Sci. U.S.A. 91: 4382-4386.
    • (1994) Proc. Natl. Acad. Sci. U.S.A. , vol.91 , pp. 4382-4386
    • Demers, G.W.1    Foster, S.A.2    Halbert, C.L.3    Galloway, D.A.4
  • 11
    • 0029964158 scopus 로고    scopus 로고
    • A reversible, p53-dependent G0/G1 cell cycle arrest induced by ribonucleotide depletion in the absence of detectable DNA damage
    • Linke SP, Clarkin KC, Di Leonardo A, Tsou A, Wahl GM. (1996) A reversible, p53-dependent G0/G1 cell cycle arrest induced by ribonucleotide depletion in the absence of detectable DNA damage. Genes Dev. 10: 934-947.
    • (1996) Genes Dev. , vol.10 , pp. 934-947
    • Linke, S.P.1    Clarkin, K.C.2    Di Leonardo, A.3    Tsou, A.4    Wahl, G.M.5
  • 12
    • 0026496885 scopus 로고
    • A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia
    • Kastan MB, Zhan Q, el-Deiry WS, et al. (1992) A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia. Cell 71: 587-597.
    • (1992) Cell , vol.71 , pp. 587-597
    • Kastan, M.B.1    Zhan, Q.2    El-Deiry, W.S.3
  • 13
    • 0028913739 scopus 로고
    • A p53-dependent mouse spindle checkpoint
    • Cross SM, Sanchez CA, Morgan CA, et al. (1995) A p53-dependent mouse spindle checkpoint. Science 267: 1353-1356.
    • (1995) Science , vol.267 , pp. 1353-1356
    • Cross, S.M.1    Sanchez, C.A.2    Morgan, C.A.3
  • 14
    • 0025784539 scopus 로고
    • Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6
    • Yonish-Rouach E, Resnitzky D, Lotem J, Sachs L, Kimchi A, Oren M. (1991) Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6. Nature 352: 345-347.
    • (1991) Nature , vol.352 , pp. 345-347
    • Yonish-Rouach, E.1    Resnitzky, D.2    Lotem, J.3    Sachs, L.4    Kimchi, A.5    Oren, M.6
  • 15
    • 0027359827 scopus 로고
    • WAF1, a potential mediator of p53 tumor suppression
    • El-Deiry WS, Tokino T, Velculescu VE, et al. (1993) WAF1, a potential mediator of p53 tumor suppression. Cell 75: 817-825.
    • (1993) Cell , vol.75 , pp. 817-825
    • El-Deiry, W.S.1    Tokino, T.2    Velculescu, V.E.3
  • 17
    • 0029973738 scopus 로고    scopus 로고
    • Role for c-Abl tyrosine kinase in growth arrest response to DNA damage
    • Yuan ZM, Huang Y, Whang Y, et al. (1996) Role for c-Abl tyrosine kinase in growth arrest response to DNA damage. Nature 382: 272-274.
    • (1996) Nature , vol.382 , pp. 272-274
    • Yuan, Z.M.1    Huang, Y.2    Whang, Y.3
  • 18
    • 0029879676 scopus 로고    scopus 로고
    • The cytostatic function of c-Abl is controlled by multiple nuclear localization signals and requires the p53 and Rb tumor suppressor gene products
    • Wen ST, Jackson PK, Van Etten RA. (1996) The cytostatic function of c-Abl is controlled by multiple nuclear localization signals and requires the p53 and Rb tumor suppressor gene products. EMBO J. 15: 1583-1595.
    • (1996) EMBO J. , vol.15 , pp. 1583-1595
    • Wen, S.T.1    Jackson, P.K.2    Van Etten, R.A.3
  • 19
    • 0028169994 scopus 로고
    • p53-dependent apoptosis suppresses tumor growth and progression in vivo
    • Symonds H, Krall L, Remington L, et al. (1994) p53-dependent apoptosis suppresses tumor growth and progression in vivo. Cell 78: 703-711.
    • (1994) Cell , vol.78 , pp. 703-711
    • Symonds, H.1    Krall, L.2    Remington, L.3
  • 20
    • 0028323294 scopus 로고
    • Abrogation of oncogene-associated apoptosis allows transformation of p53-deficient cells
    • Lowe SW, Jacks T, Housman DE, Ruley HE. (1994) Abrogation of oncogene-associated apoptosis allows transformation of p53-deficient cells. Proc. Natl. Acad. Sci. U.S.A. 91: 2026-2030.
    • (1994) Proc. Natl. Acad. Sci. U.S.A. , vol.91 , pp. 2026-2030
    • Lowe, S.W.1    Jacks, T.2    Housman, D.E.3    Ruley, H.E.4
  • 21
    • 0028227260 scopus 로고
    • Apoptosis or retinoblastoma: Alternative fates of photoreceptors expressing the HPV-16 E7 gene in the presence or absence of p53
    • erratum appears in Genes Dev. (1994) 8(14): 1738
    • Howes KA, Ransom N, Papermaster DS, Lasudry JG, Albert DM, Windle JJ. (1994) Apoptosis or retinoblastoma: Alternative fates of photoreceptors expressing the HPV-16 E7 gene in the presence or absence of p53 [erratum appears in Genes Dev. (1994) 8(14): 1738]. Genes Dev. 8: 1300-1310.
    • (1994) Genes Dev. , vol.8 , pp. 1300-1310
    • Howes, K.A.1    Ransom, N.2    Papermaster, D.S.3    Lasudry, J.G.4    Albert, D.M.5    Windle, J.J.6
  • 22
    • 0027934570 scopus 로고
    • p53-dependent apoptosis produced by Rb-deficiency in the developing mouse lens
    • Morgenbesser SD, Williams BO, Jacks T, De Pinho RA. (1994) p53-dependent apoptosis produced by Rb-deficiency in the developing mouse lens [see comments]. Nature 371: 72-74.
    • (1994) Nature , vol.371 , pp. 72-74
    • Morgenbesser, S.D.1    Williams, B.O.2    Jacks, T.3    De Pinho, R.A.4
  • 23
    • 0030021748 scopus 로고    scopus 로고
    • Specific loss of apoptotic but not cell-cycle arrest function in a human tumor derived p53 mutant
    • Rowan S, Ludwig RL, Haupt Y, et al. (1996) Specific loss of apoptotic but not cell-cycle arrest function in a human tumor derived p53 mutant. EMBO J. 15: 827-838.
    • (1996) EMBO J. , vol.15 , pp. 827-838
    • Rowan, S.1    Ludwig, R.L.2    Haupt, Y.3
  • 24
    • 0029143395 scopus 로고
    • Essential role for p53-mediated transcription in E1A-induced apoptosis
    • Sabbatini P, Lin J, Levine AJ, White E. (1995) Essential role for p53-mediated transcription in E1A-induced apoptosis. Genes Dev. 9: 2184-2192.
    • (1995) Genes Dev. , vol.9 , pp. 2184-2192
    • Sabbatini, P.1    Lin, J.2    Levine, A.J.3    White, E.4
  • 25
    • 0030013337 scopus 로고    scopus 로고
    • Transcriptional activation by p53, but not induction of the p21 gene, is essential for oncogene-mediated apoptosis
    • Attardi LD, Lowe SW, Brugarolas J, Jacks T. (1996) Transcriptional activation by p53, but not induction of the p21 gene, is essential for oncogene-mediated apoptosis. EMBO J. 15: 3693-3701.
    • (1996) EMBO J. , vol.15 , pp. 3693-3701
    • Attardi, L.D.1    Lowe, S.W.2    Brugarolas, J.3    Jacks, T.4
  • 26
    • 0028070989 scopus 로고
    • p53-dependent apoptosis in the absence of transcriptional activation of p53-target genes
    • Caelles C, Helmberg A, Karin M. (1994) p53-dependent apoptosis in the absence of transcriptional activation of p53-target genes [see comments]. Nature 370: 220-223.
    • (1994) Nature , vol.370 , pp. 220-223
    • Caelles, C.1    Helmberg, A.2    Karin, M.3
  • 27
    • 0029092356 scopus 로고
    • Induction of apoptosis in HeLa cells by trans-activation-deficient p53
    • Haupt Y, Rowan S, Shaulian E, Vousden KH, Oren M. (1995) Induction of apoptosis in HeLa cells by trans-activation-deficient p53. Genes Dev. 9: 2170-2183.
    • (1995) Genes Dev. , vol.9 , pp. 2170-2183
    • Haupt, Y.1    Rowan, S.2    Shaulian, E.3    Vousden, K.H.4    Oren, M.5
  • 28
    • 0001166257 scopus 로고    scopus 로고
    • The XPB and XPD DNA helicases are components of the p53-mediated apoptosis pathway
    • Wang XW, Vermeulen W, Coursen JD, et al. (1996) The XPB and XPD DNA helicases are components of the p53-mediated apoptosis pathway. Genes Dev. 10: 1219-1232.
    • (1996) Genes Dev. , vol.10 , pp. 1219-1232
    • Wang, X.W.1    Vermeulen, W.2    Coursen, J.D.3
  • 29
    • 0029802591 scopus 로고    scopus 로고
    • p53 levels, functional domains, and DNA damage determine the extent of the apoptotic response of tumor cells
    • Chen X, Ko LJ, Jayaraman L, Prives C. (1996) p53 levels, functional domains, and DNA damage determine the extent of the apoptotic response of tumor cells. Genes Dev. 10: 2438-2451.
    • (1996) Genes Dev. , vol.10 , pp. 2438-2451
    • Chen, X.1    Ko, L.J.2    Jayaraman, L.3    Prives, C.4
  • 30
    • 0028989236 scopus 로고
    • p53 modulation of TFIIH-associated nucleotide excision repair activity
    • Wang XW, Yeh H, Schaeffer L, et al. (1995) p53 modulation of TFIIH-associated nucleotide excision repair activity. Nat. Genet. 10: 188-195.
    • (1995) Nat. Genet. , vol.10 , pp. 188-195
    • Wang, X.W.1    Yeh, H.2    Schaeffer, L.3
  • 31
    • 0029880959 scopus 로고    scopus 로고
    • Functional interactions between p53 and the TFIIH complex are affected by tumour-associated mutations
    • Leveillard T, Andera L, Bissonnette N, et al. (1996) Functional interactions between p53 and the TFIIH complex are affected by tumour-associated mutations. EMBO J. 15: 1615-1624.
    • (1996) EMBO J. , vol.15 , pp. 1615-1624
    • Leveillard, T.1    Andera, L.2    Bissonnette, N.3
  • 32
    • 0028883179 scopus 로고
    • Tumor suppressor p53 is a direct transcriptional activator of the human box gene
    • Miyashita T, Reed JC. (1995) Tumor suppressor p53 is a direct transcriptional activator of the human box gene. Cell 80: 293-299.
    • (1995) Cell , vol.80 , pp. 293-299
    • Miyashita, T.1    Reed, J.C.2
  • 33
    • 0029003501 scopus 로고
    • Wild-type human p53 and a temperature-sensitive mutant induce Fas/APO-1 expression
    • Owen-Schaub LB, Zhang W, Cusack JC, et al. (1995) Wild-type human p53 and a temperature-sensitive mutant induce Fas/APO-1 expression. Mol. Cell. Biol. 15: 3032-3040.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 3032-3040
    • Owen-Schaub, L.B.1    Zhang, W.2    Cusack, J.C.3
  • 34
    • 0040419494 scopus 로고    scopus 로고
    • Drug-induced apoptosis in hepatoma cells is mediated by the CD95 (APO-1/Fas) receptor/ligand system and involves activation of wild-type p53
    • Muller M, Strand S, Hug H, et al. (1997) Drug-induced apoptosis in hepatoma cells is mediated by the CD95 (APO-1/Fas) receptor/ligand system and involves activation of wild-type p53. J. Clin. Invest. 99: 403-413.
    • (1997) J. Clin. Invest. , vol.99 , pp. 403-413
    • Muller, M.1    Strand, S.2    Hug, H.3
  • 35
    • 0027459198 scopus 로고
    • mdm2 expression is induced by wild-type p53 activity
    • Barak Y, Juven T, Haffner R, Oren M. (1993) mdm2 expression is induced by wild-type p53 activity. EMBO J. 12: 461-468.
    • (1993) EMBO J. , vol.12 , pp. 461-468
    • Barak, Y.1    Juven, T.2    Haffner, R.3    Oren, M.4
  • 37
    • 0028335717 scopus 로고
    • Tumor suppressor p53 is a regulator of bcl-2 and bax gene expression in vitro and in vivo
    • Miyashita T, Krajewski S, Krajewska M, et al. (1994) Tumor suppressor p53 is a regulator of bcl-2 and bax gene expression in vitro and in vivo. Oncogene 9: 1799-1805.
    • (1994) Oncogene , vol.9 , pp. 1799-1805
    • Miyashita, T.1    Krajewski, S.2    Krajewska, M.3
  • 38
    • 0027944228 scopus 로고
    • Induction of bax by genotoxic stress in human cells correlates with normal p53 status and apoptosis
    • erratum appears in Oncogene (1995) 10(6): 1259
    • Zhan Q, Fan S, Bae I, et al. (1994) Induction of bax by genotoxic stress in human cells correlates with normal p53 status and apoptosis [erratum appears in Oncogene (1995) 10(6): 1259]. Oncogene 9: 3743-3751.
    • (1994) Oncogene , vol.9 , pp. 3743-3751
    • Zhan, Q.1    Fan, S.2    Bae, I.3
  • 39
    • 0029671112 scopus 로고    scopus 로고
    • Gamma-radiation induces upregulation of Bax protein and apoptosis in radiosensitive cells in vivo
    • Kitada S, Krajewski S, Miyashita T, Krajewska M, Reed JC. (1996) Gamma-radiation induces upregulation of Bax protein and apoptosis in radiosensitive cells in vivo. Oncogene 12: 187-192.
    • (1996) Oncogene , vol.12 , pp. 187-192
    • Kitada, S.1    Krajewski, S.2    Miyashita, T.3    Krajewska, M.4    Reed, J.C.5
  • 40
    • 0029913730 scopus 로고    scopus 로고
    • mdm-2 inhibits the G1 arrest and apoptosis functions of the p53 tumor suppressor protein
    • Chen J, Wu X, Lin J, Levine AJ. (1996) mdm-2 inhibits the G1 arrest and apoptosis functions of the p53 tumor suppressor protein. Mol. Cell. Biol. 16: 2445-2452.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 2445-2452
    • Chen, J.1    Wu, X.2    Lin, J.3    Levine, A.J.4
  • 41
    • 0029985647 scopus 로고    scopus 로고
    • Cell type-specific inhibition of p53-mediated apoptosis by mdm2
    • Haupt Y, Barak Y, Oren M. (1996) Cell type-specific inhibition of p53-mediated apoptosis by mdm2. EMBO J. 15: 1596-1606.
    • (1996) EMBO J. , vol.15 , pp. 1596-1606
    • Haupt, Y.1    Barak, Y.2    Oren, M.3
  • 42
    • 0027451668 scopus 로고
    • p53-dependent apoptosis modulates the cytotoxicity of anticancer agents
    • Lowe SW, Ruley HE, Jacks T, Housman DE. (1993) p53-dependent apoptosis modulates the cytotoxicity of anticancer agents. Cell 74: 957-967.
    • (1993) Cell , vol.74 , pp. 957-967
    • Lowe, S.W.1    Ruley, H.E.2    Jacks, T.3    Housman, D.E.4
  • 43
    • 0028030791 scopus 로고
    • UV-induced nuclear accumulation of p53 is evoked through DNA damage of actively transcribed genes independent of the cell cycle
    • Yamaizumi M, Sugano T. (1994) UV-induced nuclear accumulation of p53 is evoked through DNA damage of actively transcribed genes independent of the cell cycle. Oncogens 9: 2775-2784.
    • (1994) Oncogens , vol.9 , pp. 2775-2784
    • Yamaizumi, M.1    Sugano, T.2
  • 44
    • 0029785723 scopus 로고    scopus 로고
    • Blockage of RNA polymerase as a possible trigger for Uv light-induced apoptosis
    • Ljungman M, Zhang F. (1996) Blockage of RNA polymerase as a possible trigger for Uv light-induced apoptosis. Oncogens 13: 823-831.
    • (1996) Oncogens , vol.13 , pp. 823-831
    • Ljungman, M.1    Zhang, F.2
  • 45
    • 0026769713 scopus 로고
    • An immunochemical analysis of the human nuclear phosphoprotein p53. New monoclonal antibodies and epitope mapping using recombinant p53
    • Vojtesek B, Bartek J, Midgley CA, Lane DP. (1992) An immunochemical analysis of the human nuclear phosphoprotein p53. New monoclonal antibodies and epitope mapping using recombinant p53. J. Immunol. Methods 151: 237-244.
    • (1992) J. Immunol. Methods , vol.151 , pp. 237-244
    • Vojtesek, B.1    Bartek, J.2    Midgley, C.A.3    Lane, D.P.4
  • 46
    • 0027255417 scopus 로고
    • Specific proteolytic cleavage of poly(ADP-ribose) polymerase: An early marker of chemotherapy-induced apoptosis
    • Kaufmann SH, Desnoyers S, Ottaviano Y, Davidson NE, Poirier GG. (1993) Specific proteolytic cleavage of poly(ADP-ribose) polymerase: An early marker of chemotherapy-induced apoptosis. Cancer Res. 53: 3976-3985.
    • (1993) Cancer Res. , vol.53 , pp. 3976-3985
    • Kaufmann, S.H.1    Desnoyers, S.2    Ottaviano, Y.3    Davidson, N.E.4    Poirier, G.G.5
  • 47
    • 0026720052 scopus 로고
    • The topoisomerase II inhibitor teniposide (VM-26) induces apoptosis in unstimulated mature murine lymphocytes
    • Roy C, Brown DL, Little JE, et al. (1992) The topoisomerase II inhibitor teniposide (VM-26) induces apoptosis in unstimulated mature murine lymphocytes. Exp. Cell Res. 200: 416-424.
    • (1992) Exp. Cell Res. , vol.200 , pp. 416-424
    • Roy, C.1    Brown, D.L.2    Little, J.E.3
  • 48
    • 0022445670 scopus 로고
    • Rapid colorimetric assay for cell growth and survival. Modifications to the tetrazolium dye procedure giving improved sensitivity and reliability
    • Denizot F, Lang R. (1986) Rapid colorimetric assay for cell growth and survival. Modifications to the tetrazolium dye procedure giving improved sensitivity and reliability. J. Immunol. Methods 89: 271-277.
    • (1986) J. Immunol. Methods , vol.89 , pp. 271-277
    • Denizot, F.1    Lang, R.2
  • 49
    • 0027217084 scopus 로고
    • Apoptotic death in epithelial cells: Cleavage of DNA to 300 and/or 50 kb fragments prior to or in the absence of internucleosomal fragmentation
    • Oberhammer F, Wilson JW, Dive C, et al. (1993) Apoptotic death in epithelial cells: Cleavage of DNA to 300 and/or 50 kb fragments prior to or in the absence of internucleosomal fragmentation. EMBO J. 12: 3679-3684.
    • (1993) EMBO J. , vol.12 , pp. 3679-3684
    • Oberhammer, F.1    Wilson, J.W.2    Dive, C.3
  • 50
    • 0030025773 scopus 로고    scopus 로고
    • Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours
    • Graeber TG, Osmanian C, Jacks T, et al. (1996) Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours [see comments]. Nature 379: 88-91.
    • (1996) Nature , vol.379 , pp. 88-91
    • Graeber, T.G.1    Osmanian, C.2    Jacks, T.3
  • 51
    • 0028951944 scopus 로고
    • Epstein-Barr virus efficiently immortalizes human B cells without neutralizing the function of p53
    • Allday MJ, Sinclair A, Parker G, Crawford DH, Farrell PJ. (1995) Epstein-Barr virus efficiently immortalizes human B cells without neutralizing the function of p53. EMBOJ. 14: 1382-1391.
    • (1995) EMBOJ. , vol.14 , pp. 1382-1391
    • Allday, M.J.1    Sinclair, A.2    Parker, G.3    Crawford, D.H.4    Farrell, P.J.5
  • 52
    • 0028882511 scopus 로고
    • DNA damage in human B cells can induce apoptosis, proceeding from G1/S when p53 is transactivation competent and G2/M when it is transactivation defective
    • Allday MJ, Inman GJ, Crawford DH, Farrell PJ. (1995) DNA damage in human B cells can induce apoptosis, proceeding from G1/S when p53 is transactivation competent and G2/M when it is transactivation defective. EMBO J. 14: 4994-5005.
    • (1995) EMBO J. , vol.14 , pp. 4994-5005
    • Allday, M.J.1    Inman, G.J.2    Crawford, D.H.3    Farrell, P.J.4
  • 53
    • 0030902253 scopus 로고    scopus 로고
    • Reduced RNA polymerase II transcription in intact and permeabilized Cockayne syndrome group B cells
    • Balajee AS, May A, Dianov GL, Friedberg EC, Bohr VA. (1997) Reduced RNA polymerase II transcription in intact and permeabilized Cockayne syndrome group B cells. Proc. Natl. Acad. Sci. U.S.A. 94: 4306-4311.
    • (1997) Proc. Natl. Acad. Sci. U.S.A. , vol.94 , pp. 4306-4311
    • Balajee, A.S.1    May, A.2    Dianov, G.L.3    Friedberg, E.C.4    Bohr, V.A.5
  • 54
    • 0031020871 scopus 로고    scopus 로고
    • Human transcription-repair coupling factor CSB/ERCC6 is a DNA-stimulated ATPase but is not a helicase and does not disrupt the ternary transcription complex of stalled RNA polymerase II
    • Selby CP, Sancar A. (1997) Human transcription-repair coupling factor CSB/ERCC6 is a DNA-stimulated ATPase but is not a helicase and does not disrupt the ternary transcription complex of stalled RNA polymerase II. J. Biol. Chem. 272: 1885-1890.
    • (1997) J. Biol. Chem. , vol.272 , pp. 1885-1890
    • Selby, C.P.1    Sancar, A.2
  • 55
    • 0029850732 scopus 로고    scopus 로고
    • Cockayne syndrome - A primary defect in DNA repair, transcription, both or neither?
    • Friedberg EC. (1996) Cockayne syndrome - a primary defect in DNA repair, transcription, both or neither? Bioessays 18: 731-738.
    • (1996) Bioessays , vol.18 , pp. 731-738
    • Friedberg, E.C.1
  • 56
    • 0025341294 scopus 로고
    • The genetic defect in Cockayne syndrome is associated with a defect in repair of UV-induced DNA damage in transcriptionally active DNA
    • Venema J, Mullenders LH, Natarajan AT, van Zeeland AA, Mayne LV. (1990) The genetic defect in Cockayne syndrome is associated with a defect in repair of UV-induced DNA damage in transcriptionally active DNA. Proc. Natl. Acad. Sci. U.S.A. 87: 4707-4711.
    • (1990) Proc. Natl. Acad. Sci. U.S.A. , vol.87 , pp. 4707-4711
    • Venema, J.1    Mullenders, L.H.2    Natarajan, A.T.3    Van Zeeland, A.A.4    Mayne, L.V.5
  • 57
    • 0027379353 scopus 로고
    • Preferential repair of ionizing radiation-induced damage in the transcribed strand of an active human gene is defective in Cockayne syndrome
    • Leadon SA, Cooper PK. (1993) Preferential repair of ionizing radiation-induced damage in the transcribed strand of an active human gene is defective in Cockayne syndrome. Proc. Natl. Acad. Sci. U.S.A. 90: 10499-10503.
    • (1993) Proc. Natl. Acad. Sci. U.S.A. , vol.90 , pp. 10499-10503
    • Leadon, S.A.1    Cooper, P.K.2
  • 58
    • 0029868112 scopus 로고    scopus 로고
    • The E1B 19K protein blocks apoptosis by interacting with and inhibiting the p53-inducible and death-promoting Bax protein
    • Han J, Sabbatini P, Perez D, Rao L, Modha D, White E. (1996) The E1B 19K protein blocks apoptosis by interacting with and inhibiting the p53-inducible and death-promoting Bax protein. Genes Dev. 10: 461-477.
    • (1996) Genes Dev. , vol.10 , pp. 461-477
    • Han, J.1    Sabbatini, P.2    Perez, D.3    Rao, L.4    Modha, D.5    White, E.6
  • 59
    • 0028958705 scopus 로고
    • Growth factor modulation of p53-mediated growth arrest versus apoptosis
    • Canman CE, Gilmer TM, Coutts SB, Kastan MB. (1995) Growth factor modulation of p53-mediated growth arrest versus apoptosis. Genes Dev. 9: 600-611.
    • (1995) Genes Dev. , vol.9 , pp. 600-611
    • Canman, C.E.1    Gilmer, T.M.2    Coutts, S.B.3    Kastan, M.B.4
  • 60
    • 0028861937 scopus 로고
    • p53-independent death and p53-induced protection against apoptosis in fibroblasts treated with chemotherapeutic drugs
    • Malcomson RD, Oren M, Wyllie AH, Harrison DJ. (1995) p53-independent death and p53-induced protection against apoptosis in fibroblasts treated with chemotherapeutic drugs. Br. J. Cancer 72: 952-957.
    • (1995) Br. J. Cancer , vol.72 , pp. 952-957
    • Malcomson, R.D.1    Oren, M.2    Wyllie, A.H.3    Harrison, D.J.4
  • 61
  • 62
    • 0029916932 scopus 로고    scopus 로고
    • The cyclin-dependent kinase inhibitor p21 (WAF1) is required for survival of differentiating neuroblastoma cells
    • Poluha W, Poluha DK, Chang B, et al. (1996) The cyclin-dependent kinase inhibitor p21 (WAF1) is required for survival of differentiating neuroblastoma cells. Mol. Cell. Biol. 16: 1335-1341.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 1335-1341
    • Poluha, W.1    Poluha, D.K.2    Chang, B.3
  • 64
    • 0030448650 scopus 로고    scopus 로고
    • Identification of a novel p53 functional domain that is necessary for efficient growth suppression
    • Walker KK, Levine AJ. (1996) Identification of a novel p53 functional domain that is necessary for efficient growth suppression. Proc. Natl. Acad. Sci. U.S.A. 93: 15335-15340.
    • (1996) Proc. Natl. Acad. Sci. U.S.A. , vol.93 , pp. 15335-15340
    • Walker, K.K.1    Levine, A.J.2
  • 65
    • 0031001974 scopus 로고    scopus 로고
    • A proline-rich motif in p53 is required for transactivation-independent growth arrest as induced by Gas1
    • Ruaro EM, Collavin L, Del Sal G, et al. (1997) A proline-rich motif in p53 is required for transactivation-independent growth arrest as induced by Gas1. Proc. Natl. Acad. Sci. U.S.A. 94: 4675-4680.
    • (1997) Proc. Natl. Acad. Sci. U.S.A. , vol.94 , pp. 4675-4680
    • Ruaro, E.M.1    Collavin, L.2    Del Sal, G.3
  • 66
    • 0029088143 scopus 로고
    • The Cockayne syndrome group A gene encodes a WD repeat protein that interacts with CSB protein and a subunit of RNA polymerase II TFIIH
    • Henning KA, Li L, Iyer N, et al. (1995) The Cockayne syndrome group A gene encodes a WD repeat protein that interacts with CSB protein and a subunit of RNA polymerase II TFIIH. Cell 82: 555-564.
    • (1995) Cell , vol.82 , pp. 555-564
    • Henning, K.A.1    Li, L.2    Iyer, N.3
  • 67
    • 0030025947 scopus 로고    scopus 로고
    • Interactions involving the human RNA polymerase II transcription/nucleotide excision repair complex TFIIH, the nucleotide excision repair protein XPG, and Cockayne syndrome group B (CSB) protein
    • Iyer N, Reagan MS, Wu KJ, Canagarajah B, Friedberg EC. (1996) Interactions involving the human RNA polymerase II transcription/nucleotide excision repair complex TFIIH, the nucleotide excision repair protein XPG, and Cockayne syndrome group B (CSB) protein. Biochemistry 35: 2157-2167.
    • (1996) Biochemistry , vol.35 , pp. 2157-2167
    • Iyer, N.1    Reagan, M.S.2    Wu, K.J.3    Canagarajah, B.4    Friedberg, E.C.5
  • 68
    • 0028787404 scopus 로고
    • The transcriptional elongation inhibitor 5,6-dichloro-1-beta-D-ribofuranosylbenzimidazole inhibits transcription factor IIH-associated protein kinase
    • Yankulov K, Yamashita K, Roy R, Egly JM, Bentley DL. (1995) The transcriptional elongation inhibitor 5,6-dichloro-1-beta-D-ribofuranosylbenzimidazole inhibits transcription factor IIH-associated protein kinase. J. Biol. Chem. 270: 23922-23925.
    • (1995) J. Biol. Chem. , vol.270 , pp. 23922-23925
    • Yankulov, K.1    Yamashita, K.2    Roy, R.3    Egly, J.M.4    Bentley, D.L.5
  • 69
    • 0030610565 scopus 로고    scopus 로고
    • The CDK7-cycH-p36 complex of transcription factor IIH phosphorylates p53, enhancing its sequence-specific DNA hinding activity in vitro
    • Lu H, Fisher RP, Bailey P, Levine AJ. (1997) The CDK7-cycH-p36 complex of transcription factor IIH phosphorylates p53, enhancing its sequence-specific DNA hinding activity in vitro. Mol. Cell. Biol. 17: 5923-5934.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 5923-5934
    • Lu, H.1    Fisher, R.P.2    Bailey, P.3    Levine, A.J.4
  • 70
    • 0028966941 scopus 로고
    • p53 is phosphorylated in vitro and in vivo by an ultraviolet radiation-induced protein kinase characteristic of the c-Jun kinase, JNK1
    • Milne DM, Campbell LE, Campbell DG, Meek DW. (1995) p53 is phosphorylated in vitro and in vivo by an ultraviolet radiation-induced protein kinase characteristic of the c-Jun kinase, JNK1. J. Biol. Chem. 270: 5511-5518.
    • (1995) J. Biol. Chem. , vol.270 , pp. 5511-5518
    • Milne, D.M.1    Campbell, L.E.2    Campbell, D.G.3    Meek, D.W.4
  • 71
  • 72
    • 0030134173 scopus 로고    scopus 로고
    • The stress-activated protein kinase pathway mediates cell death following injury induced by cis-platinum, UV irradiation or heat
    • Zanke BW, Boudreau K, Rubie E, et al. (1996) The stress-activated protein kinase pathway mediates cell death following injury induced by cis-platinum, UV irradiation or heat. Curr. Biol. 6: 606-613.
    • (1996) Curr. Biol. , vol.6 , pp. 606-613
    • Zanke, B.W.1    Boudreau, K.2    Rubie, E.3
  • 73
    • 0029003061 scopus 로고
    • Increased and altered DNA binding of human p53 by S and G2/M but not G1 cyclin-dependent kinases
    • Wang Y, Prives C. (1995) Increased and altered DNA binding of human p53 by S and G2/M but not G1 cyclin-dependent kinases. Nature 376: 88-91.
    • (1995) Nature , vol.376 , pp. 88-91
    • Wang, Y.1    Prives, C.2
  • 74
    • 0029132301 scopus 로고
    • Cdk2 kinase phosphorylates serine 315 of human p53 in vitro
    • Price BD, Hughes-Davies L, Park SJ. (1995) Cdk2 kinase phosphorylates serine 315 of human p53 in vitro. Oncogene 11: 73-80.
    • (1995) Oncogene , vol.11 , pp. 73-80
    • Price, B.D.1    Hughes-Davies, L.2    Park, S.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.