메뉴 건너뛰기




Volumn 132, Issue 10, 2005, Pages 2377-2388

The retinoblastoma gene pathway regulates the postmitotic state of hair cells of the mouse inner ear

Author keywords

Apoptosis; Cell cycle; Cochlea; Differentiation; Hair cell; Inner ear; Mitosis; Mouse; p21 (Cdkn1a); Polyploidy; Proliferation; Rb (Rb1); Vestibular organ

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR; PROTEIN P21; RETINOBLASTOMA PROTEIN;

EID: 21044454607     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: 10.1242/dev.01834     Document Type: Article
Times cited : (120)

References (61)
  • 2
    • 0028997799 scopus 로고
    • Cell cycle progression in gentamicin-damaged avian cochleas
    • Bhave, S. A., Stone, J. S., Rubel, E. W. and Coltrera, M. D. (1995). Cell cycle progression in gentamicin-damaged avian cochleas. J. Neurosci. 16, 4618-4628.
    • (1995) J. Neurosci. , vol.16 , pp. 4618-4628
    • Bhave, S.A.1    Stone, J.S.2    Rubel, E.W.3    Coltrera, M.D.4
  • 4
    • 0037313618 scopus 로고    scopus 로고
    • Coordinated regulation of life and death by RB
    • Chau, B. N. and Wang, J. Y. (2003). Coordinated regulation of life and death by RB. Nat. Rev. Cancer 3, 130-138.
    • (2003) Nat. Rev. Cancer , vol.3 , pp. 130-138
    • Chau, B.N.1    Wang, J.Y.2
  • 5
    • 0029830342 scopus 로고    scopus 로고
    • Retinoblastoma protein positively regulates terminal adipocyte differentiation through direct interaction with C/EBPs
    • Chen, P. L., Riley, D. J., Chen, Y. and Lee, W. H. (1996). Retinoblastoma protein positively regulates terminal adipocyte differentiation through direct interaction with C/EBPs. Genes Dev. 10, 2794-2804.
    • (1996) Genes Dev. , vol.10 , pp. 2794-2804
    • Chen, P.L.1    Riley, D.J.2    Chen, Y.3    Lee, W.H.4
  • 6
    • 0036337481 scopus 로고    scopus 로고
    • The role of Math1 in inner ear development: Uncoupling the establishment of the sensory primordium from hair cell fate determination
    • Chen, P., Johnson, J. E., Zoghbi, H. Y. and Segil, N. (2002). The role of Math1 in inner ear development: Uncoupling the establishment of the sensory primordium from hair cell fate determination. Development 129, 2495-2505.
    • (2002) Development , vol.129 , pp. 2495-2505
    • Chen, P.1    Johnson, J.E.2    Zoghbi, H.Y.3    Segil, N.4
  • 7
    • 0037936843 scopus 로고    scopus 로고
    • Progressive hearing loss in mice lacking the cyclin-dependent kinase inhibitor Ink4d
    • Chen, P., Zindy, F., Abdala, C., Liu, F., Li, X., Roussel, M. F. and Segil, N. (2003). Progressive hearing loss in mice lacking the cyclin-dependent kinase inhibitor Ink4d. Nat. Cell Biol. 5, 422-426.
    • (2003) Nat. Cell Biol. , vol.5 , pp. 422-426
    • Chen, P.1    Zindy, F.2    Abdala, C.3    Liu, F.4    Li, X.5    Roussel, M.F.6    Segil, N.7
  • 8
    • 2942574955 scopus 로고    scopus 로고
    • Cell-specific effects of RB or RB/p107 loss on retinal development implicate an intrinsically death-resistant cell-of-origin in retinoblastoma
    • Chen, D., Livne-bar, I., Vanderluit, J. L., Slack, R. S., Agochiya, M. and Bremner, R. (2004). Cell-specific effects of RB or RB/p107 loss on retinal development implicate an intrinsically death-resistant cell-of-origin in retinoblastoma. Cancer Cell 5, 539-551.
    • (2004) Cancer Cell , vol.5 , pp. 539-551
    • Chen, D.1    Livne-Bar, I.2    Vanderluit, J.L.3    Slack, R.S.4    Agochiya, M.5    Bremner, R.6
  • 10
    • 0036884829 scopus 로고    scopus 로고
    • The retinoblastoma tumour suppressor in development and cancer
    • Classon, M. and Harlow, E. (2002). The retinoblastoma tumour suppressor in development and cancer. Nat. Rev. Cancer 2, 910-917.
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 910-917
    • Classon, M.1    Harlow, E.2
  • 12
    • 0028978183 scopus 로고
    • Mice lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control
    • Deng, C., Zhang, P., Harper, J. W., Elledge, S. J. and Leder, P. (1995). Mice lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control. Cell 82, 675-684.
    • (1995) Cell , vol.82 , pp. 675-684
    • Deng, C.1    Zhang, P.2    Harper, J.W.3    Elledge, S.J.4    Leder, P.5
  • 13
    • 0032188820 scopus 로고    scopus 로고
    • Hair cells and supporting cells share a common progenitor in the avian inner ear
    • Fekete, D. M., Muthukumar, S. and Karagogeos, D. (1998). Hair cells and supporting cells share a common progenitor in the avian inner ear. J. Neurosci. 18, 7811-7821.
    • (1998) J. Neurosci. , vol.18 , pp. 7811-7821
    • Fekete, D.M.1    Muthukumar, S.2    Karagogeos, D.3
  • 16
    • 19544388583 scopus 로고    scopus 로고
    • Atoh1 null mutants show directed afferent fiber growth to undifferentiated ear sensory epithelia followed by incomplete fiber retention
    • (in press)
    • Fritzsch, B., Matei, V. A., Nichols, D. H., Bermingham, N., Jones, K., Beisel, K. W. and Wang, V. Y. (2005). Atoh1 null mutants show directed afferent fiber growth to undifferentiated ear sensory epithelia followed by incomplete fiber retention. Dev. Dyn. (in press).
    • (2005) Dev. Dyn.
    • Fritzsch, B.1    Matei, V.A.2    Nichols, D.H.3    Bermingham, N.4    Jones, K.5    Beisel, K.W.6    Wang, V.Y.7
  • 17
    • 0027499060 scopus 로고
    • Interaction of myogenic factors and the retinoblastoma protein mediates muscle cell commitment and differentiation
    • Gu, W., Schneider, J. W., Condorelli, G., Kaushal, S., Mahdavi, V. and Nadal-Ginard, B. (1993). Interaction of myogenic factors and the retinoblastoma protein mediates muscle cell commitment and differentiation. Cell 72, 309-324.
    • (1993) Cell , vol.72 , pp. 309-324
    • Gu, W.1    Schneider, J.W.2    Condorelli, G.3    Kaushal, S.4    Mahdavi, V.5    Nadal-Ginard, B.6
  • 18
    • 0029034451 scopus 로고
    • MyoD-induced expression of p21 inhibits cyclin-dependent kinase activity upon myocyte terminal differentiation
    • Guo, K., Wang, J., Andres, V., Smith, R. C. and Walsh, K. (1995). MyoD-induced expression of p21 inhibits cyclin-dependent kinase activity upon myocyte terminal differentiation. Mol. Cell. Biol. 15, 3823-3829.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 3823-3829
    • Guo, K.1    Wang, J.2    Andres, V.3    Smith, R.C.4    Walsh, K.5
  • 19
    • 0035576791 scopus 로고    scopus 로고
    • Inactivation of the retinoblastoma tumor suppressor induces apoptosis protease-activating factor-1 dependent and independent apoptotic pathways during embryogenesis
    • Guo, Z., Yikang, S., Yoshida, H., Mak, T. W. and Zacksenhaus, E. (2001). Inactivation of the retinoblastoma tumor suppressor induces apoptosis protease-activating factor-1 dependent and independent apoptotic pathways during embryogenesis. Cancer Res. 61, 8395-8400.
    • (2001) Cancer Res. , vol.61 , pp. 8395-8400
    • Guo, Z.1    Yikang, S.2    Yoshida, H.3    Mak, T.W.4    Zacksenhaus, E.5
  • 20
  • 22
    • 0030828073 scopus 로고    scopus 로고
    • Mitosis-specific phosphorylation of histone H3 initiates primarily within pericentromeric heterochromatin during G2 and spreads in an ordered fashion coincident with mitotic chromosome condensation
    • Hendzel, M. J., Wei, Y., Mancini, M. A., Van Hooser, A., Ranalli, T., Brinkley, B. R., Bazett-Jones, D. P. and Allis, C. D. (1997). Mitosis-specific phosphorylation of histone H3 initiates primarily within pericentromeric heterochromatin during G2 and spreads in an ordered fashion coincident with mitotic chromosome condensation. Chromosoma 106, 348-360.
    • (1997) Chromosoma , vol.106 , pp. 348-360
    • Hendzel, M.J.1    Wei, Y.2    Mancini, M.A.3    Van Hooser, A.4    Ranalli, T.5    Brinkley, B.R.6    Bazett-Jones, D.P.7    Allis, C.D.8
  • 24
    • 0030922363 scopus 로고    scopus 로고
    • The retinoblastoma gene family is differentially expressed during embryogenesis
    • Jiang, Z., Zacksenhaus, E., Gallie, B. L. and Phillips, R. A. (1997). The retinoblastoma gene family is differentially expressed during embryogenesis. Oncogene 14, 1789-1797.
    • (1997) Oncogene , vol.14 , pp. 1789-1797
    • Jiang, Z.1    Zacksenhaus, E.2    Gallie, B.L.3    Phillips, R.A.4
  • 25
    • 0034331291 scopus 로고    scopus 로고
    • E2F1 and p53 are dispensable, whereas p21(Waf1/Cip1) cooperates with Rb to restrict endoreduplication and apoptosis during skeletal myogenesis
    • Jiang, Z., Liang, P., Leng, R., Guo, Z., Liu, Y., Liu, X., Bubnic, S., Keating, A., Murray, D., Goss, P. and Zacksenhaus, E. (2000). E2F1 and p53 are dispensable, whereas p21(Waf1/Cip1) cooperates with Rb to restrict endoreduplication and apoptosis during skeletal myogenesis. Dev. Biol. 227, 8-41.
    • (2000) Dev. Biol. , vol.227 , pp. 8-41
    • Jiang, Z.1    Liang, P.2    Leng, R.3    Guo, Z.4    Liu, Y.5    Liu, X.6    Bubnic, S.7    Keating, A.8    Murray, D.9    Goss, P.10    Zacksenhaus, E.11
  • 26
    • 0035808345 scopus 로고    scopus 로고
    • Retinoblastoma gene promoter directs transgene expression exclusively to the nervous system
    • Jiang, Z., Guo, Z., Saad, F. A., Ellis, J. and Zacksenhaus, E. (2001). Retinoblastoma gene promoter directs transgene expression exclusively to the nervous system. J. Biol. Chem. 276, 593-600.
    • (2001) J. Biol. Chem. , vol.276 , pp. 593-600
    • Jiang, Z.1    Guo, Z.2    Saad, F.A.3    Ellis, J.4    Zacksenhaus, E.5
  • 27
    • 0026744563 scopus 로고
    • Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis
    • Lee, E. Y., Chang, C. Y., Hu, N., Wang, Y. C., Lai, C. C., Herrup, K., Lee, W. H. and Bradley, A. (1992). Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis. Nature 359, 288-294.
    • (1992) Nature , vol.359 , pp. 288-294
    • Lee, E.Y.1    Chang, C.Y.2    Hu, N.3    Wang, Y.C.4    Lai, C.C.5    Herrup, K.6    Lee, W.H.7    Bradley, A.8
  • 28
    • 0037607660 scopus 로고    scopus 로고
    • Expression of the retinoblastoma family of tumor suppressors during murine embryonic orofacial development
    • Leezer, J. L., Hackmiller, R. C., Greene, R. M. and Pisano, M. M. (2002). Expression of the retinoblastoma family of tumor suppressors during murine embryonic orofacial development. Orthod. Craniofacial Res. 6, 32-47.
    • (2002) Orthod. Craniofacial Res. , vol.6 , pp. 32-47
    • Leezer, J.L.1    Hackmiller, R.C.2    Greene, R.M.3    Pisano, M.M.4
  • 29
    • 0035796491 scopus 로고    scopus 로고
    • Cell-autonomous and non-cell-autonomous functions of the Rb tumor suppressor in developing central nervous system
    • Lipinski, M. M., Macleod, K. F., Williams, B. O., Mullaney, T. L., Crowley, D. and Jacks, T. (2001). Cell-autonomous and non-cell-autonomous functions of the Rb tumor suppressor in developing central nervous system. EMBO J. 20, 3402-3413.
    • (2001) EMBO J. , vol.20 , pp. 3402-3413
    • Lipinski, M.M.1    Macleod, K.F.2    Williams, B.O.3    Mullaney, T.L.4    Crowley, D.5    Jacks, T.6
  • 30
    • 0034619773 scopus 로고    scopus 로고
    • E2F1 mediates ectopic proliferation and stage-specific p53-dependent apoptosis but not aberrant differentiation in the ocular lens of Rb deficient fetuses
    • Liu, Y. and Zacksenhaus, E. (2000). E2F1 mediates ectopic proliferation and stage-specific p53-dependent apoptosis but not aberrant differentiation in the ocular lens of Rb deficient fetuses. Oncogene 19, 6065-6073.
    • (2000) Oncogene , vol.19 , pp. 6065-6073
    • Liu, Y.1    Zacksenhaus, E.2
  • 31
    • 0029910628 scopus 로고    scopus 로고
    • Loss of Rb activates both p53-dependent and independent cell death pathways in the developing mouse nervous system
    • Macleod, K. F., Hu, Y. and Jacks, T. (1996). Loss of Rb activates both p53-dependent and independent cell death pathways in the developing mouse nervous system. EMBO J. 15, 6178-6188.
    • (1996) EMBO J. , vol.15 , pp. 6178-6188
    • Macleod, K.F.1    Hu, Y.2    Jacks, T.3
  • 32
    • 0037305849 scopus 로고    scopus 로고
    • Conditional mutation of Rb causes cell cycle defects without apoptosis in the central nervous system
    • MacPherson, D., Sage, J., Crowley, D., Trumpp, A., Bronson, R. T. and Jacks, T. (2003). Conditional mutation of Rb causes cell cycle defects without apoptosis in the central nervous system. Mol. Cell. Biol. 3, 1044-1053.
    • (2003) Mol. Cell. Biol. , vol.3 , pp. 1044-1053
    • MacPherson, D.1    Sage, J.2    Crowley, D.3    Trumpp, A.4    Bronson, R.T.5    Jacks, T.6
  • 33
    • 2942512013 scopus 로고    scopus 로고
    • Cell type-specific effects of Rb deletion in the murine retina
    • MacPherson, D., Sage, J., Kim, T., Ho, D., McLaughlin, M. E. and Jacks, T. (2004). Cell type-specific effects of Rb deletion in the murine retina. Genes Dev. 18, 1681-1694.
    • (2004) Genes Dev. , vol.18 , pp. 1681-1694
    • MacPherson, D.1    Sage, J.2    Kim, T.3    Ho, D.4    McLaughlin, M.E.5    Jacks, T.6
  • 34
    • 0027934570 scopus 로고
    • p53-dependent apoptosis produced by Rb-deficiency in the developing mouse lens
    • Morgenbesser, S. D., Williams, B. O., Jacks, T. and DePinho, R. A. (1994). p53-dependent apoptosis produced by Rb-deficiency in the developing mouse lens. Nature 371, 72-74.
    • (1994) Nature , vol.371 , pp. 72-74
    • Morgenbesser, S.D.1    Williams, B.O.2    Jacks, T.3    DePinho, R.A.4
  • 35
    • 0842324788 scopus 로고    scopus 로고
    • Recycling the cell cycle: Cyclins revisited
    • Murray, A. W. (2004). Recycling the cell cycle: cyclins revisited. Cell 116, 221-234.
    • (2004) Cell , vol.116 , pp. 221-234
    • Murray, A.W.1
  • 36
    • 0029960519 scopus 로고    scopus 로고
    • Skeletal muscle cells lacking the retinoblastoma protein display defects in muscle gene expression and accumulate in S and G2 phases of the cell cycle
    • Novitch, B. G., Mulligan, G. J., Jacks, T. and Lassar, A. B. (1996). Skeletal muscle cells lacking the retinoblastoma protein display defects in muscle gene expression and accumulate in S and G2 phases of the cell cycle. J. Cell Biol. 135, 441-456.
    • (1996) J. Cell Biol. , vol.135 , pp. 441-456
    • Novitch, B.G.1    Mulligan, G.J.2    Jacks, T.3    Lassar, A.B.4
  • 37
    • 0033529030 scopus 로고    scopus 로고
    • pRb is required for MEF2-dependent gene expression as well as cell-cycle arrest during skeletal muscle differentiation
    • Novitch, B. G., Spicer, D. B., Kim, P. S., Cheung, W. L. and Lassar, A. B. (1999). pRb is required for MEF2-dependent gene expression as well as cell-cycle arrest during skeletal muscle differentiation. Curr. Biol. 9, 449-459.
    • (1999) Curr. Biol. , vol.9 , pp. 449-459
    • Novitch, B.G.1    Spicer, D.B.2    Kim, P.S.3    Cheung, W.L.4    Lassar, A.B.5
  • 38
    • 0034646629 scopus 로고    scopus 로고
    • Proliferation of intimal smooth muscle cells. Attenuation of basic fibroblast growth factor 2-stimulated proliferation is associated with increased expression of cell cycle inhibitors
    • Olson, N. E., Kozlowski, J. and Reidy, M. A. (2000). Proliferation of intimal smooth muscle cells. Attenuation of basic fibroblast growth factor 2-stimulated proliferation is associated with increased expression of cell cycle inhibitors. J. Biol. Chem. 275, 11270-11277.
    • (2000) J. Biol. Chem. , vol.275 , pp. 11270-11277
    • Olson, N.E.1    Kozlowski, J.2    Reidy, M.A.3
  • 39
    • 0037945196 scopus 로고    scopus 로고
    • Expression and function of FGF10 in mammalian inner ear development
    • Pauley, S., Beisel, K., Wright, T., Pirvola, U., Ornitz, D. and Fritzsch, B. (2003). Expression and function of FGF10 in mammalian inner ear development. Dev. Dyn. 227, 203-215.
    • (2003) Dev. Dyn. , vol.227 , pp. 203-215
    • Pauley, S.1    Beisel, K.2    Wright, T.3    Pirvola, U.4    Ornitz, D.5    Fritzsch, B.6
  • 42
    • 4344684497 scopus 로고    scopus 로고
    • Fgf9 signaling regulates inner ear morphogenesis through epithelial-mesenchymal interactions
    • Pirvola, U., Zhang, X., Mantela, J., Ornitz, D. M. and Ylikoski, J. (2004). Fgf9 signaling regulates inner ear morphogenesis through epithelial-mesenchymal interactions. Dev. Biol. 273, 350-360.
    • (2004) Dev. Biol. , vol.273 , pp. 350-360
    • Pirvola, U.1    Zhang, X.2    Mantela, J.3    Ornitz, D.M.4    Ylikoski, J.5
  • 43
    • 0642349263 scopus 로고    scopus 로고
    • The cell cycle and the development and regeneration of hair cells
    • Ryan, A. F. (2003). The cell cycle and the development and regeneration of hair cells. Curr. Top. Dev. Biol. 57, 449-466.
    • (2003) Curr. Top. Dev. Biol. , vol.57 , pp. 449-466
    • Ryan, A.F.1
  • 44
    • 0014040729 scopus 로고
    • Development of the inner ear of the mouse: A radioautographic study of terminal mitoses
    • Ruben, R. J. (1967). Development of the inner ear of the mouse: a radioautographic study of terminal mitoses. Acta Otolaryngol. Suppl. 220, 1-44.
    • (1967) Acta Otolaryngol. Suppl. , vol.220 , pp. 1-44
    • Ruben, R.J.1
  • 46
    • 0031930466 scopus 로고    scopus 로고
    • Stable binding to E2F is not required for the retinoblastoma protein to activate transcription, promote differentiation, and suppress tumor cell growth
    • Sellers, W. R., Novitch, B. G., Miyake, S., Heith, A., Otterson, G. A., Kaye, F. J., Lassar, A. B. and Kaelin, W. G. Jr (1998). Stable binding to E2F is not required for the retinoblastoma protein to activate transcription, promote differentiation, and suppress tumor cell growth. Genes Dev. 12, 95-106.
    • (1998) Genes Dev. , vol.12 , pp. 95-106
    • Sellers, W.R.1    Novitch, B.G.2    Miyake, S.3    Heith, A.4    Otterson, G.A.5    Kaye, F.J.6    Lassar, A.B.7    Kaelin Jr., W.G.8
  • 47
    • 0347762556 scopus 로고    scopus 로고
    • From polyploidy to aneuploidy, genome instability and cancer
    • Storchova, Z. and Pellman, D. (2004). From polyploidy to aneuploidy, genome instability and cancer. Nature Rev. 5, 45-54.
    • (2004) Nature Rev. , vol.5 , pp. 45-54
    • Storchova, Z.1    Pellman, D.2
  • 49
    • 0032159103 scopus 로고    scopus 로고
    • Mutation of E2f-1 suppresses apoptosis and inappropriate S phase entry and extends survival of Rb-deficient mouse embryos
    • Tsai, K. Y., Hu, Y., Macleod, K. F., Crowley, D., Yamasaki, L. and Jacks, T. (1998). Mutation of E2f-1 suppresses apoptosis and inappropriate S phase entry and extends survival of Rb-deficient mouse embryos. Mol. Cell 3, 293-304.
    • (1998) Mol. Cell , vol.3 , pp. 293-304
    • Tsai, K.Y.1    Hu, Y.2    Macleod, K.F.3    Crowley, D.4    Yamasaki, L.5    Jacks, T.6
  • 50
    • 0032442522 scopus 로고    scopus 로고
    • Histone H3 phosphorylation is required for the initiation, but not maintenance, of mammalian chromosome condensation
    • Van Hooser, A., Goodrich, D. W., Allis, C. D., Brinkley, B. R. and Mancini, M. A. (1998). Histone H3 phosphorylation is required for the initiation, but not maintenance, of mammalian chromosome condensation. J. Cell Sci. 111, 3497-3506.
    • (1998) J. Cell Sci. , vol.111 , pp. 3497-3506
    • Van Hooser, A.1    Goodrich, D.W.2    Allis, C.D.3    Brinkley, B.R.4    Mancini, M.A.5
  • 51
    • 0034682037 scopus 로고    scopus 로고
    • Cell-cycle inhibitors: Three families united by a common cause
    • Vidal, A. and Koff, A. (2000). Cell-cycle inhibitors: three families united by a common cause. Gene 247, 1-15.
    • (2000) Gene , vol.247 , pp. 1-15
    • Vidal, A.1    Koff, A.2
  • 52
    • 0029033861 scopus 로고
    • The retinoblastoma protein and cell cycle control
    • Weinberg, R. A. (1995). The retinoblastoma protein and cell cycle control. Cell 81, 323-330.
    • (1995) Cell , vol.81 , pp. 323-330
    • Weinberg, R.A.1
  • 54
    • 0000792471 scopus 로고
    • In situ hybridization and the three-dimensional construction of serial sections
    • (ed.. A. J. Copp and D. L. Cockroft), Oxford, UK: IRL Press
    • Wilkinson, D. G and Green, J. (1991). In situ hybridization and the three-dimensional construction of serial sections. In: Postimplantation Mammalian Embryos (ed.. A. J. Copp and D. L. Cockroft), pp. 155-17 1. Oxford, UK: IRL Press.
    • (1991) Postimplantation Mammalian Embryos , pp. 155-171
    • Wilkinson, D.G.1    Green, J.2
  • 55
    • 13744263559 scopus 로고    scopus 로고
    • Math1 regulates development of the sensory epithelium in the mammalian cochlea
    • Woods, C., Montcouquiol, M. and Kelley M. W. (2004). Math1 regulates development of the sensory epithelium in the mammalian cochlea. Nat. Neurosci. 7, 1310-1318.
    • (2004) Nat. Neurosci. , vol.7 , pp. 1310-1318
    • Woods, C.1    Montcouquiol, M.2    Kelley, M.W.3
  • 58
    • 0029819994 scopus 로고    scopus 로고
    • pRb controls proliferation, differentiation, and death of skeletal muscle cells and other lineages during embryogenesis
    • Zacksenhaus, E., Jiang, Z., Chung, D., Marth, J. D., Phillips, R. A. and Gallie, B. L. (1996). pRb controls proliferation, differentiation, and death of skeletal muscle cells and other lineages during embryogenesis. Genes Dev. 10, 3051-3064.
    • (1996) Genes Dev. , vol.10 , pp. 3051-3064
    • Zacksenhaus, E.1    Jiang, Z.2    Chung, D.3    Marth, J.D.4    Phillips, R.A.5    Gallie, B.L.6
  • 60
    • 0034127584 scopus 로고    scopus 로고
    • Overexpression of Math1 induces robust production of extra hair cells in postnatal rat inner ears
    • Zheng, J. L. and Gao, W. O. (2000). Overexpression of Math1 induces robust production of extra hair cells in postnatal rat inner ears. Nat. Neurosci. 3, 580-586.
    • (2000) Nat. Neurosci. , vol.3 , pp. 580-586
    • Zheng, J.L.1    Gao, W.O.2
  • 61
    • 0034604349 scopus 로고    scopus 로고
    • The deaf jerker mouse has a mutation in the gene encoding the espin actin-bundling proteins of hair cell stereocilia and lacks espins
    • Zheng, L., Sekerkova, G., Vranich, K., Tilney, L. G., Mugnaini, E. and Bartles, J. R. (2000). The deaf jerker mouse has a mutation in the gene encoding the espin actin-bundling proteins of hair cell stereocilia and lacks espins. Cell 102, 377-385.
    • (2000) Cell , vol.102 , pp. 377-385
    • Zheng, L.1    Sekerkova, G.2    Vranich, K.3    Tilney, L.G.4    Mugnaini, E.5    Bartles, J.R.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.