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Volumn 23, Issue 15, 2003, Pages 5256-5268

Rb and N-ras function together to control differentiation in the mouse

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL CULTURE; CELL PROLIFERATION; CONTROLLED STUDY; CORRELATION ANALYSIS; EMBRYO; GENE DELETION; GENE EXPRESSION; GENETIC TRANSCRIPTION; HYPOTHESIS; MOUSE; MYOBLAST; NONHUMAN; NUCLEOTIDE SEQUENCE; ONCOGENE N RAS; PRIORITY JOURNAL; RETINOBLASTOMA TUMOR SUPPRESSOR GENE; SKELETAL MUSCLE; TUMOR SUPPRESSOR GENE; ZYGOSITY;

EID: 0041590939     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.23.15.5256-5268.2003     Document Type: Article
Times cited : (48)

References (72)
  • 1
    • 0024376173 scopus 로고
    • Ras oncogenes in human cancer: A review
    • Bos, J. L. 1989. ras oncogenes in human cancer: a review. Cancer Res. 49:4682-4689.
    • (1989) Cancer Res. , vol.49 , pp. 4682-4689
    • Bos, J.L.1
  • 2
    • 0035265833 scopus 로고    scopus 로고
    • dpl-1 DP and eft-1 E2F act with lin-35 Rb to antagonize Ras signaling in C. elegans vulval development
    • Ceol, C. J., and H. R. Horvitz. 2001. dpl-1 DP and eft-1 E2F act with lin-35 Rb to antagonize Ras signaling in C. elegans vulval development. Mol. Cell 7:461-473.
    • (2001) Mol. Cell , vol.7 , pp. 461-473
    • Ceol, C.J.1    Horvitz, H.R.2
  • 3
    • 0029830342 scopus 로고    scopus 로고
    • Retinoblastoma protein positively regulates terminal adipocyte differentiation through direct interaction with C/EBPs
    • Chen, P.-L., D. J. Riley, Y. Chen, and W.-H. Lee. 1996. Retinoblastoma protein positively regulates terminal adipocyte differentiation through direct interaction with C/EBPs. Genes Dev. 10:2794-2804.
    • (1996) Genes Dev. , vol.10 , pp. 2794-2804
    • Chen, P.-L.1    Riley, D.J.2    Chen, Y.3    Lee, W.-H.4
  • 4
    • 0030031409 scopus 로고    scopus 로고
    • Retinoblastoma protein directly interacts with and activates the transcription factor NF-IL6
    • Chen, P.-L., D. J. Riley, S. Chen-Kiang, and W.-H. Lee. 1996. Retinoblastoma protein directly interacts with and activates the transcription factor NF-IL6. Proc. Natl. Acad. Sci. USA 93:465-469.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 465-469
    • Chen, P.-L.1    Riley, D.J.2    Chen-Kiang, S.3    Lee, W.-H.4
  • 7
    • 0029088326 scopus 로고
    • Targeted disruption of the glucocorticoid receptor gene blocks adrenergic chromaffin cell development and severely retards lung maturation
    • Cole, T. J., J. A. Blendy, P. Monaghan, K. Krieglstein, S. W., A. Aguzzi, G. Fantuzzi, E. Hummler, K. Unsicker, and G. Schutz. 1995. Targeted disruption of the glucocorticoid receptor gene blocks adrenergic chromaffin cell development and severely retards lung maturation. Genes Dev. 9:1608-1621.
    • (1995) Genes Dev. , vol.9 , pp. 1608-1621
    • Cole, T.J.1    Blendy, J.A.2    Monaghan, P.3    Krieglstein, K.4    Aguzzi, A.5    Fantuzzi, G.6    Hummler, E.7    Unsicker, K.8    Schutz, G.9
  • 11
    • 0027499060 scopus 로고
    • Interaction of myogenic factors and the retinoblastoma protein mediates muscle cell commitment and differentiation
    • Gu, W., J. W. Schneider, G. Condorelli, S. Kaushal, V. Mahdavi, and B. Nadal-Ginard. 1993. Interaction of myogenic factors and the retinoblastoma protein mediates muscle cell commitment and differentiation. Cell 72:309-324.
    • (1993) Cell , vol.72 , pp. 309-324
    • Gu, W.1    Schneider, J.W.2    Condorelli, G.3    Kaushal, S.4    Mahdavi, V.5    Nadal-Ginard, B.6
  • 12
    • 0037135552 scopus 로고    scopus 로고
    • Deregulated MAPK activity prevents adipocyte differentiation in fibroblasts lacking the retinoblastoma protein
    • Hansen, J. B., R. K. Petersen, C. Jorgensen, and K. Kristiansen. 2002. Deregulated MAPK activity prevents adipocyte differentiation in fibroblasts lacking the retinoblastoma protein. J. Biol. Chem. 277:26335-26339.
    • (2002) J. Biol. Chem. , vol.277 , pp. 26335-26339
    • Hansen, J.B.1    Petersen, R.K.2    Jorgensen, C.3    Kristiansen, K.4
  • 13
    • 0033786378 scopus 로고    scopus 로고
    • Rb function in cell-cycle regulation and apoptosis
    • Harbour, J. W., and D. C. Dean. 2000. Rb function in cell-cycle regulation and apoptosis. Nat. Cell Biol. 2:E65-E67.
    • (2000) Nat. Cell Biol. , vol.2
    • Harbour, J.W.1    Dean, D.C.2
  • 14
    • 0034306996 scopus 로고    scopus 로고
    • The Rb/E2F pathway: Expanding roles and emerging paradigms
    • Harbour, J. W., and D. C. Dean. 2000. The Rb/E2F pathway: expanding roles and emerging paradigms. Genes Dev. 14:2393-2409.
    • (2000) Genes Dev. , vol.14 , pp. 2393-2409
    • Harbour, J.W.1    Dean, D.C.2
  • 15
    • 0028988697 scopus 로고
    • Effects of heterozygosity for the Rb-1t19neo allele in the mouse
    • Harrison, D. J., M. L. Hooper, J. F. Armstrong, and A. R. Clarke. 1995. Effects of heterozygosity for the Rb-1t19neo allele in the mouse. Oncogene 20:1615-1620.
    • (1995) Oncogene , vol.20 , pp. 1615-1620
    • Harrison, D.J.1    Hooper, M.L.2    Armstrong, J.F.3    Clarke, A.R.4
  • 16
    • 0024602765 scopus 로고
    • Oncogene mediated repression of glucocorticoid hormone response elements and glucocorticoid receptor levels
    • Hock, J. R., A. Ziemiecki, R. Klemenz, R. Friis, and B. Groner. 1989. Oncogene mediated repression of glucocorticoid hormone response elements and glucocorticoid receptor levels. Cancer Res. 49:2266s-2274s.
    • (1989) Cancer Res. , vol.49
    • Hock, J.R.1    Ziemiecki, A.2    Klemenz, R.3    Friis, R.4    Groner, B.5
  • 17
    • 0028174064 scopus 로고
    • Heterozygous Rb-1 delta 20/+ mice are predisposed to tumors of the pituitary gland with a nearly complete penetrance
    • Hu, N., A. Gutsmann, D. C. Herbert, A. Bradley, W.-H. Lee, and E. Y. Lee. 1994. Heterozygous Rb-1 delta 20/+ mice are predisposed to tumors of the pituitary gland with a nearly complete penetrance. Oncogene 9:1021-1027.
    • (1994) Oncogene , vol.9 , pp. 1021-1027
    • Hu, N.1    Gutsmann, A.2    Herbert, D.C.3    Bradley, A.4    Lee, W.-H.5    Lee, E.Y.6
  • 20
    • 0035808345 scopus 로고    scopus 로고
    • Retinoblastoma gene promoter directs transgene expression exclusively to the nervous system
    • Jiang, Z., Z. Guo, F. A. Saad, J. Ellis, and E. Zacksenhaus. 2001. Retinoblastoma gene promoter directs transgene expression exclusively to the nervous system. J. Biol. Chem. 276:593-600.
    • (2001) J. Biol. Chem. , vol.276 , pp. 593-600
    • Jiang, Z.1    Guo, Z.2    Saad, F.A.3    Ellis, J.4    Zacksenhaus, E.5
  • 23
    • 0031917171 scopus 로고    scopus 로고
    • Ras-GRF activates Ha-Ras, but not N-Ras or K-Ras 4B, protein in vivo
    • Jones, M. K., and J. H. Jackson. 1998. Ras-GRF activates Ha-Ras, but not N-Ras or K-Ras 4B, protein in vivo. J. Biol. Chem. 273:1782-1787.
    • (1998) J. Biol. Chem. , vol.273 , pp. 1782-1787
    • Jones, M.K.1    Jackson, J.H.2
  • 26
    • 0028980337 scopus 로고
    • Val inhibits myogenesis without altering the DNA binding or transcriptional activities of the myogenic basic helix-loop-helix factors
    • Val inhibits myogenesis without altering the DNA binding or transcriptional activities of the myogenic basic helix-loop-helix factors. Mol. Cell. Biol. 15:5205-5213.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 5205-5213
    • Kong, Y.1    Johnson, S.E.2    Taparowsky, E.J.3    Konieczny, S.F.4
  • 27
    • 0028028073 scopus 로고
    • Novel mechanism of C/EBPβ (NF-M) transcriptional control: Activation through derepression
    • Kowenz-Leutz, E., G. Twamley, S. Ansieau, and A. Leutz. 1994. Novel mechanism of C/EBPβ (NF-M) transcriptional control: activation through derepression. Genes Dev. 8:2781-2791.
    • (1994) Genes Dev. , vol.8 , pp. 2781-2791
    • Kowenz-Leutz, E.1    Twamley, G.2    Ansieau, S.3    Leutz, A.4
  • 28
    • 0028293649 scopus 로고
    • Partial inactivation of RB product in a family with incomplete penetrance of familial retinoblastoma and benign retinal tumors
    • Kratzke, R. A., G. A. Otterson, A. Hogg, A. B. Coxon, J. Geradts, J. K. Cowell, and F. J. Kaye. 1994. Partial inactivation of RB product in a family with incomplete penetrance of familial retinoblastoma and benign retinal tumors. Oncogene 9:1321-1326.
    • (1994) Oncogene , vol.9 , pp. 1321-1326
    • Kratzke, R.A.1    Otterson, G.A.2    Hogg, A.3    Coxon, A.B.4    Geradts, J.5    Cowell, J.K.6    Kaye, F.J.7
  • 29
    • 0034458854 scopus 로고    scopus 로고
    • Regulation of the functional interaction between cyclin D1 and the estrogen receptor
    • Lamb, J., M. H. Ladha, C. McMahon, R. L. Sutherland, and M. E. Ewen. 2000. Regulation of the functional interaction between cyclin D1 and the estrogen receptor. Mol. Cell. Biol. 20:8667-8675.
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 8667-8675
    • Lamb, J.1    Ladha, M.H.2    McMahon, C.3    Sutherland, R.L.4    Ewen, M.E.5
  • 30
    • 0034609818 scopus 로고    scopus 로고
    • Id2 is a retinoblastoma protein target and mediates signalling by Myc oncoproteins
    • Lasorella, A., M. Noseda, M. Beyna, and A. Iavarone. 2000. Id2 is a retinoblastoma protein target and mediates signalling by Myc oncoproteins. Nature 407:592-598.
    • (2000) Nature , vol.407 , pp. 592-598
    • Lasorella, A.1    Noseda, M.2    Beyna, M.3    Iavarone, A.4
  • 32
    • 0028131540 scopus 로고
    • Dual roles of the retinoblastoma protein in cell cycle regulation and neuron differentiation
    • Lee, E. Y.-H. P., N. Hu, S.-S. F. Yuan, L. A. Cox, A. Bradley, W.-H. Lee, and K. Herrup. 1994. Dual roles of the retinoblastoma protein in cell cycle regulation and neuron differentiation. Genes Dev. 8:2008-2021.
    • (1994) Genes Dev. , vol.8 , pp. 2008-2021
    • Lee, E.Y.-H.P.1    Hu, N.2    Yuan, S.-S.F.3    Cox, L.A.4    Bradley, A.5    Lee, W.-H.6    Herrup, K.7
  • 33
    • 0000220411 scopus 로고    scopus 로고
    • The retinoblastoma protein is linked to the activation of Ras
    • Lee, K. Y., M. H. Ladha, C. McMahon, and M. E. Ewen. 1999. The retinoblastoma protein is linked to the activation of Ras. Mol. Cell. Biol. 19:7724-7732.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 7724-7732
    • Lee, K.Y.1    Ladha, M.H.2    McMahon, C.3    Ewen, M.E.4
  • 34
    • 0030995824 scopus 로고    scopus 로고
    • Myc and Ras collaborate in inducing accumulation of active cyclin E/Cdk2 and E2F
    • Leone, G., J. DeGregori, R. Sears, L. Jakoi, and J. R. Nevins. 1997. Myc and Ras collaborate in inducing accumulation of active cyclin E/Cdk2 and E2F. Nature 387:422-426.
    • (1997) Nature , vol.387 , pp. 422-426
    • Leone, G.1    DeGregori, J.2    Sears, R.3    Jakoi, L.4    Nevins, J.R.5
  • 35
    • 0033590071 scopus 로고    scopus 로고
    • The retinoblastoma gene family in differentiation and development
    • Lipinski, M. M., and T. Jacks. 1999. The retinoblastoma gene family in differentiation and development. Oncogene 18:7873-7882.
    • (1999) Oncogene , vol.18 , pp. 7873-7882
    • Lipinski, M.M.1    Jacks, T.2
  • 36
    • 0034619773 scopus 로고    scopus 로고
    • E2F1 mediates ectopic proliferation and stage-specific p53-dependent apoptosis but not aberrant differentiation in the ocular lens of Rb deficient fetuses
    • Liu, Y., and E. Zacksenhaus. 2000. E2F1 mediates ectopic proliferation and stage-specific p53-dependent apoptosis but not aberrant differentiation in the ocular lens of Rb deficient fetuses. Oncogene 19:6065-6073.
    • (2000) Oncogene , vol.19 , pp. 6065-6073
    • Liu, Y.1    Zacksenhaus, E.2
  • 37
    • 0032433854 scopus 로고    scopus 로고
    • lin-35 and lin-53, two genes that antagonize a C. elegans Ras pathway, encode proteins similar to Rb and its binding protein RbAp48
    • Lu, X., and H. R. Horvitz. 1998. lin-35 and lin-53, two genes that antagonize a C. elegans Ras pathway, encode proteins similar to Rb and its binding protein RbAp48. Cell 95:981-991.
    • (1998) Cell , vol.95 , pp. 981-991
    • Lu, X.1    Horvitz, H.R.2
  • 38
    • 0026052173 scopus 로고
    • Developmental regulation of creatine kinase gene by myogenic factors in embryonic mouse and chick skeletal muscle
    • Lyons, G. E., S. Muhlebach, A. Moser, R. Masood, B. M. Paterson, M. E. Buckingham, and J. C. Perriard. 1991. Developmental regulation of creatine kinase gene by myogenic factors in embryonic mouse and chick skeletal muscle. Development 113:1017-1029.
    • (1991) Development , vol.113 , pp. 1017-1029
    • Lyons, G.E.1    Muhlebach, S.2    Moser, A.3    Masood, R.4    Paterson, B.M.5    Buckingham, M.E.6    Perriard, J.C.7
  • 39
    • 0001139669 scopus 로고    scopus 로고
    • Ras pathways to cell cycle control and cell transformation
    • Malumbres, M., and A. Pellicer. 1998. Ras pathways to cell cycle control and cell transformation. Front. Biosci. 3:d887-d912.
    • (1998) Front. Biosci. , vol.3
    • Malumbres, M.1    Pellicer, A.2
  • 41
    • 0031105404 scopus 로고    scopus 로고
    • Ras signalling is required for inactivation of tumour suppressor pRb cell-cycle control protein
    • Mittnacht, S., H. Paterson, M. F. Olson, and C. J. Marshall. 1997. Ras signalling is required for inactivation of tumour suppressor pRb cell-cycle control protein. Curr. Biol. 7:219-221.
    • (1997) Curr. Biol. , vol.7 , pp. 219-221
    • Mittnacht, S.1    Paterson, H.2    Olson, M.F.3    Marshall, C.J.4
  • 42
    • 0027499295 scopus 로고
    • Phosphorylation at threonine-235 by a ras-dependent mitogen-activated protein kinase cascade is essential for transcription factor NF-IL6
    • Nakajima, T., S. Kinoshita, T. Sasagawa, K. Sasaki, M. Naruto, and T. Kishimoto. 1993. Phosphorylation at threonine-235 by a ras-dependent mitogen-activated protein kinase cascade is essential for transcription factor NF-IL6. Proc. Natl. Acad. Sci. USA 90:2207-2211.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 2207-2211
    • Nakajima, T.1    Kinoshita, S.2    Sasagawa, T.3    Sasaki, K.4    Naruto, M.5    Kishimoto, T.6
  • 43
    • 0029960519 scopus 로고    scopus 로고
    • Skeletal muscle cells lacking the retinoblastoma protein display defects in muscle gene expression and accumulate in S and G2 phases of the cell cycle
    • Novitch, B. G., G. J. Mulligan, T. Jacks, and A. B. Lassar. 1996. Skeletal muscle cells lacking the retinoblastoma protein display defects in muscle gene expression and accumulate in S and G2 phases of the cell cycle. J. Cell Biol. 135:441-456.
    • (1996) J. Cell Biol. , vol.135 , pp. 441-456
    • Novitch, B.G.1    Mulligan, G.J.2    Jacks, T.3    Lassar, A.B.4
  • 44
    • 0033529030 scopus 로고    scopus 로고
    • pRb is required for MEF2-dependent gene expression as well as cell-cycle arrest during skeletal muscle differentiation
    • Novitch, B. G., D. B. Spicer, P. S. Kim, W. L. Cheung, and A. B. Lassar. 1999. pRb is required for MEF2-dependent gene expression as well as cell-cycle arrest during skeletal muscle differentiation. Curr. Biol. 9:449-459.
    • (1999) Curr. Biol. , vol.9 , pp. 449-459
    • Novitch, B.G.1    Spicer, D.B.2    Kim, P.S.3    Cheung, W.L.4    Lassar, A.B.5
  • 45
    • 0023354739 scopus 로고
    • The oncogenic forms of N-ras and H-ras prevent skeletal myoblast differentiation
    • Olson, E. N., G. Spitz, and M. A. Tainsky. 1987. The oncogenic forms of N-ras and H-ras prevent skeletal myoblast differentiation. Mol. Cell. Biol. 7:2104-2111.
    • (1987) Mol. Cell. Biol. , vol.7 , pp. 2104-2111
    • Olson, E.N.1    Spitz, G.2    Tainsky, M.A.3
  • 46
    • 0035265832 scopus 로고    scopus 로고
    • The C. elegans E2F-and DP-related proteins are required for embryonic asymmetry and negatively regulate Ras/MAPK signaling
    • Page, B. D., S. Guedes, D. Waring, and J. R. Pries. 2001. The C. elegans E2F-and DP-related proteins are required for embryonic asymmetry and negatively regulate Ras/MAPK signaling. Mol. Cell 7:451-460.
    • (2001) Mol. Cell , vol.7 , pp. 451-460
    • Page, B.D.1    Guedes, S.2    Waring, D.3    Pries, J.R.4
  • 48
    • 0034840401 scopus 로고    scopus 로고
    • Activated MEK1 binds the nuclear MyoD transcriptional complex to repress transactivation
    • Perry, R. L. S., M. H. Parker, and M. A. Rudnicki. 2001. Activated MEK1 binds the nuclear MyoD transcriptional complex to repress transactivation. Mol. Cell 8:291-301.
    • (2001) Mol. Cell , vol.8 , pp. 291-301
    • Perry, R.L.S.1    Parker, M.H.2    Rudnicki, M.A.3
  • 49
    • 0030989152 scopus 로고    scopus 로고
    • Signaling through mitogen-activated protein kinase and Rac/Rho does not duplicate the effects of activated Ras on skeletal myogenesis
    • Ramocki, M. B., S. E. Johnson, M. A. White, C. L. Ashendel, S. F. Konieczny, and E. J. Taparowsky. 1997. Signaling through mitogen-activated protein kinase and Rac/Rho does not duplicate the effects of activated Ras on skeletal myogenesis. Mol. Cell. Biol. 17:3547-3555.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 3547-3555
    • Ramocki, M.B.1    Johnson, S.E.2    White, M.A.3    Ashendel, C.L.4    Konieczny, S.F.5    Taparowsky, E.J.6
  • 50
    • 0032504148 scopus 로고    scopus 로고
    • A role for RalGDS and a novel Ras effector in the Ras-mediated inhibition of skeletal myogenesis
    • Ramocki, M. B., M. A. White, S. F. Konieczny, and E. J. Taparowsky. 1998. A role for RalGDS and a novel Ras effector in the Ras-mediated inhibition of skeletal myogenesis. J. Biol. Chem. 273:17696-17701.
    • (1998) J. Biol. Chem. , vol.273 , pp. 17696-17701
    • Ramocki, M.B.1    White, M.A.2    Konieczny, S.F.3    Taparowsky, E.J.4
  • 51
    • 0030861015 scopus 로고    scopus 로고
    • Cellular ras gene activity is required for full neoplastic transformation by the large tumor antigen of SV40
    • Raptis, L., H. L. Brownell, M. J. Corbley, K. W. Wood, D. Wang, and T. Haliotis. 1997. Cellular ras gene activity is required for full neoplastic transformation by the large tumor antigen of SV40. Cell Growth Diff. 8:891-901.
    • (1997) Cell Growth Diff. , vol.8 , pp. 891-901
    • Raptis, L.1    Brownell, H.L.2    Corbley, M.J.3    Wood, K.W.4    Wang, D.5    Haliotis, T.6
  • 52
    • 0033517763 scopus 로고    scopus 로고
    • Involvement of the Sp1 site in ras-mediated downregulation of the RECK metastasis suppressor gene
    • Sasahara, R. M., C. Takahashi, and M. Noda. 1999. Involvement of the Sp1 site in ras-mediated downregulation of the RECK metastasis suppressor gene. Biochem. Biophys. Res. Commun. 264:668-675.
    • (1999) Biochem. Biophys. Res. Commun. , vol.264 , pp. 668-675
    • Sasahara, R.M.1    Takahashi, C.2    Noda, M.3
  • 53
    • 0024956317 scopus 로고
    • Expression of two myogenic regulatory factors myogenin and MyoD1 during mouse embryogenesis
    • Sassoon, D., G. Lyons, W. E. Wright, V. Lin, A. Lassar, H. Weintraub, and M. Buckingham. 1989. Expression of two myogenic regulatory factors myogenin and MyoD1 during mouse embryogenesis. Nature 341:303-307.
    • (1989) Nature , vol.341 , pp. 303-307
    • Sassoon, D.1    Lyons, G.2    Wright, W.E.3    Lin, V.4    Lassar, A.5    Weintraub, H.6    Buckingham, M.7
  • 55
    • 0024457919 scopus 로고
    • Tumor-promoting phorbol ester and ras oncogene expression inhibit the glucocorticoid-dependent transcription from the mouse mammary tumor virus long terminal repeat
    • Screpanti, V. A., M. Maroder, E. Petrangeli, L. Frati, and A. Gulino. 1989. Tumor-promoting phorbol ester and ras oncogene expression inhibit the glucocorticoid-dependent transcription from the mouse mammary tumor virus long terminal repeat. Mol. Endocrinol. 3:1659-1665.
    • (1989) Mol. Endocrinol. , vol.3 , pp. 1659-1665
    • Screpanti, V.A.1    Maroder, M.2    Petrangeli, E.3    Frati, L.4    Gulino, A.5
  • 56
    • 0037023755 scopus 로고    scopus 로고
    • Signaling networks that link cell proliferation and cell fate
    • Sears, R. C., and J. R. Nevins. 2002. Signaling networks that link cell proliferation and cell fate. J. Biol. Chem. 277:11617-11620.
    • (2002) J. Biol. Chem. , vol.277 , pp. 11617-11620
    • Sears, R.C.1    Nevins, J.R.2
  • 57
    • 0030678627 scopus 로고    scopus 로고
    • Role of the retinoblastoma protein in the pathogenesis of human cancer
    • Sellers, W. R., and W. G. J. Kaelin. 1997. Role of the retinoblastoma protein in the pathogenesis of human cancer. J. Clin. Oncol. 15:3301-3312.
    • (1997) J. Clin. Oncol. , vol.15 , pp. 3301-3312
    • Sellers, W.R.1    Kaelin, W.G.J.2
  • 58
    • 0031930466 scopus 로고    scopus 로고
    • Stable binding to E2F is not required for the retinoblastoma protein to activate transcription, promote differentiation, and suppress tumor growth
    • Sellers, W. R., B. G. Novitch, S. Miyake, A. Heith, G. A. Otterson, F. J. Kaye, A. B. Lassar, and W. G. J. Kaelin. 1998. Stable binding to E2F is not required for the retinoblastoma protein to activate transcription, promote differentiation, and suppress tumor growth. Genes Dev. 12:96-106.
    • (1998) Genes Dev. , vol.12 , pp. 96-106
    • Sellers, W.R.1    Novitch, B.G.2    Miyake, S.3    Heith, A.4    Otterson, G.A.5    Kaye, F.J.6    Lassar, A.B.7    Kaelin, W.G.J.8
  • 59
    • 0028986413 scopus 로고
    • A role for the retinoblastoma protein in potentiating transcriptional activation of the glucocorticoid receptor
    • Singh, P., J. Coe, and W. Hong. 1995. A role for the retinoblastoma protein in potentiating transcriptional activation of the glucocorticoid receptor. Nature 374:562-565.
    • (1995) Nature , vol.374 , pp. 562-565
    • Singh, P.1    Coe, J.2    Hong, W.3
  • 60
    • 0030011705 scopus 로고    scopus 로고
    • Characterization of a human MSX-2 cDNA and its fragment isolated as a transformation suppressor gene against v-Ki-ras oncogene
    • Takahashi, C., N. Akiyama, T. Matsuzaki, S. Takai, H. Kitayama, and M. Noda. 1996. Characterization of a human MSX-2 cDNA and its fragment isolated as a transformation suppressor gene against v-Ki-ras oncogene. Oncogene 12:2137-2146.
    • (1996) Oncogene , vol.12 , pp. 2137-2146
    • Takahashi, C.1    Akiyama, N.2    Matsuzaki, T.3    Takai, S.4    Kitayama, H.5    Noda, M.6
  • 61
    • 0034840594 scopus 로고    scopus 로고
    • The retinoblastoma protein acts as a transcriptional coactivator required for osteogenic differentiation
    • Thomas, D. M., S. A. Carty, D. M. Piscopo, J.-S. Lee, W.-F. Wang, W. C. Forrester, and P. W. Hinds. 2001. The retinoblastoma protein acts as a transcriptional coactivator required for osteogenic differentiation. Mol. Cell 8:303-316.
    • (2001) Mol. Cell , vol.8 , pp. 303-316
    • Thomas, D.M.1    Carty, S.A.2    Piscopo, D.M.3    Lee, J.-S.4    Wang, W.-F.5    Forrester, W.C.6    Hinds, P.W.7
  • 62
    • 85211294124 scopus 로고    scopus 로고
    • The retinoblastoma tumour suppressor protein and cancer
    • D. M. Swallow and Y. H. Edwards (ed.). BIOS Scientific Publishers, Oxford, United Kingdom
    • Tiemann, F., K. Masunuru, and P. W. Hinds. 1997. The retinoblastoma tumour suppressor protein and cancer, p. 163-185. In D. M. Swallow and Y. H. Edwards (ed.), Protein dysfunction and human genetic disease. BIOS Scientific Publishers, Oxford, United Kingdom.
    • (1997) Protein Dysfunction and Human Genetic Disease , pp. 163-185
    • Tiemann, F.1    Masunuru, K.2    Hinds, P.W.3
  • 64
    • 0032159103 scopus 로고    scopus 로고
    • Mutation of E2f-1 suppresses apoptosis and inappropriate S phase entry and extends survival of Rb-deficient mouse embryos
    • Tsai, K. Y., Y. Hu, K. F. Macleod, D. Crowley, L. Yamasaki, and T. Jacks. 1998. Mutation of E2f-1 suppresses apoptosis and inappropriate S phase entry and extends survival of Rb-deficient mouse embryos. Mol. Cell 2:293-304.
    • (1998) Mol. Cell , vol.2 , pp. 293-304
    • Tsai, K.Y.1    Hu, Y.2    Macleod, K.F.3    Crowley, D.4    Yamasaki, L.5    Jacks, T.6
  • 66
    • 0033588843 scopus 로고    scopus 로고
    • Developmental defects and tumor predisposition in Rb mutant mice
    • Vooijs, M., and A. Berns. 1999. Developmental defects and tumor predisposition in Rb mutant mice. Oncogene 18:5293-5303.
    • (1999) Oncogene , vol.18 , pp. 5293-5303
    • Vooijs, M.1    Berns, A.2
  • 67
    • 0027182833 scopus 로고
    • Tumor suppressor genes
    • Weinberg, R. 1993. Tumor suppressor genes. Neuron 11:191-196.
    • (1993) Neuron , vol.11 , pp. 191-196
    • Weinberg, R.1
  • 68
    • 0029033861 scopus 로고
    • The retinoblastoma protein and cell cycle control
    • Weinberg, R. A. 1995. The retinoblastoma protein and cell cycle control. Cell 81:323-330.
    • (1995) Cell , vol.81 , pp. 323-330
    • Weinberg, R.A.1
  • 70
    • 0031003117 scopus 로고    scopus 로고
    • Ras is required for a limited number of cell fates and not for general proliferation in Caenorhabditis elegans
    • Yochem, J., M. Sundaram, and M. Han. 1997. Ras is required for a limited number of cell fates and not for general proliferation in Caenorhabditis elegans. Mol. Cell. Biol. 17:2716-2722.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 2716-2722
    • Yochem, J.1    Sundaram, M.2    Han, M.3
  • 71
    • 0029819994 scopus 로고    scopus 로고
    • pRb controls proliferation, differentiation, and death of skeletal muscle cells and other lineages during embryogenesis
    • Zacksenhaus, E., Z. Jiang, D. Chung, J. D. Marth, R. A. Phillips, and B. L. Gallie. 1996. pRb controls proliferation, differentiation, and death of skeletal muscle cells and other lineages during embryogenesis. Genes Dev. 10:3051-3064.
    • (1996) Genes Dev. , vol.10 , pp. 3051-3064
    • Zacksenhaus, E.1    Jiang, Z.2    Chung, D.3    Marth, J.D.4    Phillips, R.A.5    Gallie, B.L.6
  • 72
    • 0035118893 scopus 로고    scopus 로고
    • E2F3 contributes both to the inappropriate proliferation and to the apoptosis arising in Rb mutant embryos
    • Ziebold, U., T. Reza, A. Caron, and J. A. Lees. 2001. E2F3 contributes both to the inappropriate proliferation and to the apoptosis arising in Rb mutant embryos. Genes Dev. 15:386-391.
    • (2001) Genes Dev. , vol.15 , pp. 386-391
    • Ziebold, U.1    Reza, T.2    Caron, A.3    Lees, J.A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.