Expression of interleukin-1β converting enzyme gene family and bcl-2 gene family in the rat brain following permanent occlusion of the middle cerebral artery

Journal of Cerebral Blood Flow and Metabolism

Volumn 17, Issue 1, 1997, Pages 11-18

  Asahi, Minoru ^b   Hoshimaru, Minoru ^a   Uemura, Yoshihiko ^b   Tokime, Tomoo ^b   Kojima, Masahiro ^b   Ohtsuka, Toshiyuki ^b   Matsuura, Nobuki ^b   Aoki, Tomokazu ^b   Shibahara, Keiichi ^b   Kikuchi, Haruhiko ^b  

^a KYOTO UNIVERSITY   (Japan)

^b NONE

Author keywords

Apoptosis; bcl 2; Focal cerebral ischemia; Interleukin 1 converting enzyme; Northern blot analysis; Programmed cell death

Indexed keywords

DNA FRAGMENT; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN ISCHEMIA; CELL DEATH; CONTROLLED STUDY; DNA DEGRADATION; GENE EXPRESSION; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

EID: 0031030729     PISSN: 0271678X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00004647-199701000-00003     Document Type: Article

References (38)

1. Boise LH, González-García M, Postema CE, et al. (1993) bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death. Cell 74:597-608
2. Boudreau N, Sympson CJ, Werb Z, Bissell MJ (1995) Suppression of ICE and apoptosis in mammary epithelial cells by extracellular matrix. Science 267:891-893
3. Charriaut-Marlangue C, Margaill I, Plotkine M, Ben-Ari Y (1995) Early endonuclease activation following reversible focal ischemia in the rat brain. J Cereb Blood Flow Metab 15:385-388
4. Charriaut-Marlangue C, Margaill I, Represa A, Popovici T, Plotkine M, Ben-Ari (1996) Apoptosis and necrosis after reversible focal ischemia: an in situ DNA fragmentation analysis. J Cereb Blood Flow Metab 16:186-194
5. Chen J, Graham SH, Chan PH, Lan J, Zhou RL, Simon RP (1995) bcl-2 is expressed in neurons that survive focal ischemia in the rat. Neuroreport 6:394-398
6. Chen M, Quintans J, Fuks Z, Thompson C, Kufe DW, Weichselbaum RR (1995) Suppression of bcl-2 messenger RNA production may mediate apoptosis after ionizing radiation, tumor necrosis factor alpha, and ceramide. Cancer Res 55:991-994
7. Ellis HM, Horvitz HR (1986) Genetic control of programmed cell death in the nematode C. elegans. Cell 44:817-829
8. Elliss RE, Yuan JY, Horvitz HR (1991) Mechanisms and functions of cell death. Annu Rev Cell Biol 7:663-698
9. Farlie PG, Dringen R, Rees SM, Kannourakis G, Bernard O (1995) bcl-2 transgene expression can protect neurons against developmental and induced cell death. Proc Natl Acad Sci USA 92:4397-4401
10. Faucheu C, Diu A, Chan AW, et al. (1995) A novel human protease similar to the interleukin-1β converting enzyme induces apoptosis in transfected cells. EMBO J 14:1914-1922
11. Fernandes-Alnemri T, Litwack G, Alnemri ES (1994) CPP32, a novel human apoptotic protein with homology to Caenorhabditis elegans cell death protein Ced-3 and mammmalian interleukin-1β-converting enzyme. J Biol Chem 269:30761-30764
12. Fernandes-Alnemri T, Litwack G, Alnemri ES (1995) Mch2, a new member of the apoptotic Ced-3/Ice cysteine protease gene family. Cancer Res 55:2737-2742
13. Gavrieli Y, Sherman Y, Ben-Sasson SA (1992) Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J Cell Biol 119:493-501
14. González-García M, García I, Ding L, O'Shea S, Boise LH, Thompson CB, Núñez G (1995) bcl-x is expressed in embryonic and postnatal neural tissues and functions to prevent neuronal cell death. Proc Natl Acad Sci USA 92:4304-4308
15. Hengartner MO, Ellis RE, Horvitz HR (1992) Caenorhabditis elegans gene ced-9 protects cells from programmed cell death. Nature 356:494-499
16. Hengartner MO, Horvitz HR (1994) C. elegans cell survival gene ced-9 encodes a functional homology of the mammalian proto-oncogene bcl-2. Cell 76:665-676
17. Hoshimaru M, Ray J, Sah DWY, Gage FH (1996) Differentiation of the immortalized adult neruonal progenitor cell line HC2S2 into neruons by regulatable suppression of the v-myc oncogene. Proc Natl Acad Sci USA 93:1518-1523
18. Kamens J, Paskind M, Hugunin M, et al. (1995) Identification and characterization of ICH-2, a novel member of the interleukin-1β-converting enzyme family of cysteine proteases. J Biol Chem 270: 15250-15256
19. Keane KM, Giegel DA, Lipinski WJ, Callahan MJ, Shivers BD (1995) Cloning, tissue expression and regulation of rat interleukin 1 beta converting enzyme. Cytokine 7:105-110
20. Kumar S (1995) Inhibition of apoptosis by the expression of antisense Nedd2. FEBS Lett 368:69-72
21. Kumar S, Kinoshita M, Noda M, Copeland NG, Jenkins NA (1994) Induction of apoptosis by the mouse Nedd2 gene, which encodes a protein similar to the product of the Caenorhabditis elegans cell death gene ced-3 and the mammalian IL-1β-converting enzyme. Genes Dev 8:1613-1626
22. Li Y, Chopp M, Jiang N, Yao F, Zaloga C (1995) Temporal profile of in situ DNA fragmentation after transient middle cerebral artery occlusion in the rat. J Cereb Blood Flow Metab 15:389-397
23. Linnik MD, Zobrist RH, Hatfield MD (1993) Evidence supporting a role for programmed cell death in focal cerebral ischemia in rats. Stroke 24:2002-2008
24. MacManus JP, Hill IE, Huang ZG, Rasquinha I, Xue D, Buchan AM (1994) DNA damage consistent with apoptosis in transient focal ischaemic neocortex. Neuroreport 5:493-496
25. Martin SJ, Green DR (1995) Protease activation during apoptosis: death by a thousand cuts? Cell 82:349-352
26. Martinou JC, Dubois-Dauphin M, Staple JK, et al. (1994) Overexpression of BCL-2 in transgenic mice protects neurons from naturally occurring cell death and experimental ischemia. Neuron 13:1017-1030
27. Miura M, Zhu H, Rotello R, Hartwieg EA, Yuan J (1993) Induction of apoptosis in fibroblasts by IL-1β-converting enzyme, a mammalian homolog of the C. elegans cell death gene ced-3. Cell 75:653-660
28. Shimazaki K, Ishida A, Kawai N (1994) Increase in bcl-2 oncoprotein and the tolerance to ischemia-induced neuronal death in the gerbil hippocampus. Neurosci Res 20:95-99
29. Siesjö BK (1992) Pathophysiology and treatment of focal cerebral ischemia. Part II: Mechanisms of damage and treatment. J Neurosurg 77:337-354
30. Takahashi JB, Hoshimaru M, Kikuchi H, Hatanaka M (1993) Developmental expression of trkB and low-affinity NGF receptor in the rat retina. Neurosci Lett 151:174-177
31. Tewari M, Quan LT, O'Rourke K, et al. (1995) Yama/CPP32 beta, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase. Cell 81:801-809
32. Tominaga T, Kure S, Narisawa K, Yoshimoto T (1993) Endonuclease activation following focal ischemic injury in the rat brain. Brain Res 608:21-26
33. Tsujimoto Y, Cossman I, Jaffe E, Croce CM (1985) Involvement of the bcl-2 gene in human follicular lymphoma. Science 228:1440-1443
34. Wang L, Miura M, Bergeron L, Zhu H, Yuan J (1994) Ich-1, an Ice/ced-3-related gene, encodes both positive and negative regulators of programmed cell death. Cell 78:739-750
35. Whyte M, Evan G (1995) Apoptosis. The last cut is the deepest. Nature 376:17-18
36. Yuan J, Shaham S, Ledoux S, Ellis HM, Horvitz HR (1993) The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1β-converting enzyme. Cell 75:641-652
37. Zea Longa E, Weinstein PR, Carlson S, Cummins R (1989) Reversible middle cerebral artery occlusion without craniectomy in rats. Stroke 20:84-91
38. Zhang RL, Chopp M, Chen H, Garcia JH (1994) Temporal profile of ischemic tissue damage, neutrophil response, and vascular plugging following permanent and transient (2H) middle cerebral artery occlusion in the rat [published erratum appears in J Neurol Sci 1994 126:96]. J Neurol Sci 125:3-10