17-β-estradiol induces heat shock proteins in brain arteries and potentiates ischemic heat shock protein induction in glia and neurons

Journal of Cerebral Blood Flow and Metabolism

Volumn 22, Issue 2, 2002, Pages 183-195

  Lu, Aigang ^a   Ran, Rui Qiong ^a   Clark, Joseph ^a   Reilly, Melinda ^a   Nee, Alex ^a   Sharp, Frank R ^a  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

Author keywords

Arteries; Blood vessels; Estrogen; Heat shock; Heat shock factor; Heat shock proteins; Ischemia; Smooth muscle cells; Stroke

Indexed keywords

E4389; ESTRADIOL; HEAT SHOCK PROTEIN; HEAT SHOCK PROTEIN 25; HEAT SHOCK PROTEIN 27; HEAT SHOCK PROTEIN 70; HEME OXYGENASE 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BRAIN ARTERY; BRAIN INJURY; BRAIN ISCHEMIA; CAROTID ARTERY; CONTROLLED STUDY; FEMALE; GERBIL; GLIA; HEAT SHOCK; IMMUNOCYTOCHEMISTRY; MALE; NERVE CELL; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; RAT; STROKE; VASCULAR SMOOTH MUSCLE; WESTERN BLOTTING;

EID: 0036173216     PISSN: 0271678X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00004647-200202000-00006     Document Type: Article

References (46)

1. Immunocytochemical demonstration of oestrogen receptor beta in blood vessels of the female rat
2. Nitric oxide-inducible expression of heme oxygenase-1 in human cells. Translation-independent stabilization of the mRNA and evidence for direct action of nitric oxide
3. Protection against necrosis but not apoptosis by heat-stress proteins in vascular smooth muscle cells: Evidence for distinct modes of cell death
4. Nitric oxide induces heme oxygenase-1 via mitogen-activated protein kinases ERK and p38
5. Neurons overexpressing heme oxygenase-1 resist oxidative stress-mediated cell death
6. Autoradiographic localization of estrogen and androgen receptors in the sexually dimorphic area and other regions of the gerbil brain
7. Estrogen-induced resistance to osteoblast apoptosis is associated with increased hsp27 expression
8. Heme oxygenase: Recent advances in understanding its regulation and role
9. Peroxynitrite induces haem oxygenase-1 in vascular endothelial cells: A link to apoptosis
10. Structure and organisation of a murine gene encoding small heat-shock protein Hsp25
11. Neuroprotection by estradiol
12. Neuroprotective effects of estrogens: Potential mechanisms of action
13. Estrogen as a neuroprotectant in stroke
14. Gene regulation of heme oxygenase-1 as a therapeutic target
15. Induction of 27-kDa heat shock protein following cerebral ischemia in a rat model of ischemic tolerance
16. Heat-shock factor-1, steroid hormones, and regulation of heat-shock protein expression in the heart
17. The 70-kDa heat shock cognate protein (Hsc73) gene is enhanced by ovarian hormones in the ventromedial hypothalamus
18. Overexpression of heme oxygenase-1 in human pulmonary epithelial cells results in cell growth arrest and increased resistance to hyperoxia
19. A role for HSP27 in sensory neuron survival
20. Small stress proteins as novel regulators of apoptosis. Heat shock protein 27 blocks Fas/APO-1- and staurosporine-induced cell death
21. Nongenomic, ER-mediated activation of endothelial nitric oxide synthase: How does it work? What does it mean?
22. Estrogen induction of glial heat shock proteins: Implications for hypothalamic aging
23. Estrogenic regulation of heat shock protein 90 kDa in the rat ventromedial hypothalamus and uterus
24. Hormonal regulation of HSP27 expression in human endometrial epithelial and stromal cells
25. Overexpression of heme oxygenase-1 is neuroprotective in a model of permanent middle cerebral artery occlusion in transgenic mice
26. Localization of androgen and estrogen receptors in rat and primate tissues
27. Accelerated growth and senescence of arterial endothelial cells expressing the small molecular weight heat-shock protein HSP27
28. Role of estrogen receptor/Sp1 complexes in estrogen-induced heat shock protein 27 gene expression
29. Functional synergy between the transcription factor Sp1 and the estrogen receptor
30. Transcriptional activation of heat shock protein 27 gene expression by 17beta-estradiol and modulation by antiestrogens and aryl hydrocarbon receptor agonists
31. Mice overexpressing rat heat shock protein 70 are protected against cerebral infarction
32. Estrogen signals to the preservation of endothelial cell form and function
33. Estrogen stimulates heat shock protein 90 binding to endothelial nitric oxide synthase in human vascular endothelial cells. Effects on calcium sensitivity and NO release
34. Heat shock proteins increase resistance to apoptosis
35. Heat-shock protein protection
36. Induction of heme oxygenase protein protects neurons in cortex and striatum, but not in hippocampus, against transient forebrain ischemia
37. Evidence for oestrogenic regulation of heat shock protein expression in human endometrium and steroid-responsive cell lines
38. Estrogen-mediated neuroprotection after experimental stroke in male rats
39. Heme oxygenase-1 attenuates vascular remodeling following balloon injury in rat carotid arteries
40. Protection of neuronal cells from apoptosis by Hsp27 delivered with a herpes simplex virus-based vector
41. Changes in heat shock protein-90 and -70 messenger ribonucleic acid in uterine tissues of the ewe in relation to parturition and regulation by estradiol and progesterone
42. Heat-shock proteins as death determinants
43. Retrovirus-mediated HO gene transfer into endothelial cells protects against oxidant-induced injury
44. Estrogen dependent expression of heat shock transcription factor: Implications for uterine synthesis of heat shock proteins
45. The neuroprotective potential of heat shock protein 70 (HSP70)
46. Repression of heat shock transcription factor HSF1 activation by HSP90 (HSP90 complex) that forms a stress-sensitive complex with HSF1