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Volumn 205, Issue , 2005, Pages 170-189

Non-malignant clonal expansions of CD8+ memory T cells in aged individuals

Author keywords

[No Author keywords available]

Indexed keywords

CD8 ANTIGEN; CYTOKINE;

EID: 20344389743     PISSN: 01052896     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.0105-2896.2005.00265.x     Document Type: Review
Times cited : (62)

References (88)
  • 1
    • 2442684151 scopus 로고    scopus 로고
    • Memory CD8 T-cell differentiation during viral infection
    • Wherry EJ, Ahmed R. Memory CD8 T-cell differentiation during viral infection. J Virol 2004;78:5535-5545.
    • (2004) J Virol , vol.78 , pp. 5535-5545
    • Wherry, E.J.1    Ahmed, R.2
  • 2
    • 0037074012 scopus 로고    scopus 로고
    • Molecular and functional profiling of memory CD8 T cell differentiation
    • Kaech SM, Hemby S, Kersh E, Ahmed R. Molecular and functional profiling of memory CD8 T cell differentiation. Cell 2002;111: 837-851.
    • (2002) Cell , vol.111 , pp. 837-851
    • Kaech, S.M.1    Hemby, S.2    Kersh, E.3    Ahmed, R.4
  • 3
    • 0038655228 scopus 로고    scopus 로고
    • Cytokine control of memory T-cell development and survival
    • Schluns KS, Lefrancois L. Cytokine control of memory T-cell development and survival. Nat Rev Immunol 2003;3:269-279.
    • (2003) Nat Rev Immunol , vol.3 , pp. 269-279
    • Schluns, K.S.1    Lefrancois, L.2
  • 4
    • 0030036342 scopus 로고    scopus 로고
    • Induction of bystander T cell proliferation by viruses and type I interferon in vivo
    • Tough DF, Borrow P, Sprent J. Induction of bystander T cell proliferation by viruses and type I interferon in vivo. Science 1996;272:1947-1950.
    • (1996) Science , vol.272 , pp. 1947-1950
    • Tough, D.F.1    Borrow, P.2    Sprent, J.3
  • 6
    • 0032211699 scopus 로고    scopus 로고
    • IL-15 receptor maintains lymphoid homeostasis by supporting lymphocyte homing and proliferation
    • Lodolce JP, et al. IL-15 receptor maintains lymphoid homeostasis by supporting lymphocyte homing and proliferation. Immunity 1998;9:669-676.
    • (1998) Immunity , vol.9 , pp. 669-676
    • Lodolce, J.P.1
  • 7
    • 0034610970 scopus 로고    scopus 로고
    • Reversible defects in natural killer and memory CD8 T cell lineages in interleukin 15-deficient mice
    • Kennedy MK, et al. Reversible defects in natural killer and memory CD8 T cell lineages in interleukin 15-deficient mice. J Exp Med 2000;191:771-780.
    • (2000) J Exp Med , vol.191 , pp. 771-780
    • Kennedy, M.K.1
  • 9
    • 0037124341 scopus 로고    scopus 로고
    • Interleukin 15 is required for proliferative renewal of virus-specific memory CD8 T cells
    • Becker TC, et al. Interleukin 15 is required for proliferative renewal of virus-specific memory CD8 T cells. J Exp Med 2002;195:1541-1548.
    • (2002) J Exp Med , vol.195 , pp. 1541-1548
    • Becker, T.C.1
  • 10
    • 0037124362 scopus 로고    scopus 로고
    • Cytokine requirements for acute and basal homeostatic proliferation of naive and memory CD8+ T cells
    • Goldrath AW, et al. Cytokine requirements for acute and basal homeostatic proliferation of naive and memory CD8+ T cells. J Exp Med 2002;195:1515-1522.
    • (2002) J Exp Med , vol.195 , pp. 1515-1522
    • Goldrath, A.W.1
  • 11
    • 0037093844 scopus 로고    scopus 로고
    • Cutting edge: Requirement for IL-15 in the generation of primary and memory antigen-specific CD8 T cells
    • Schluns KS, Williams K, Ma A, Zheng XX, Lefrancois L. Cutting edge: Requirement for IL-15 in the generation of primary and memory antigen-specific CD8 T cells. J Immunol 2002;168:4827-4831.
    • (2002) J Immunol , vol.168 , pp. 4827-4831
    • Schluns, K.S.1    Williams, K.2    Ma, A.3    Zheng, X.X.4    Lefrancois, L.5
  • 13
    • 0034332403 scopus 로고    scopus 로고
    • Interleukin-7 mediates the homeostasis of naive and memory CD8 T cells in vivo
    • Schluns KS, Kieper WC, Jameson SC, Lefrancois L. Interleukin-7 mediates the homeostasis of naive and memory CD8 T cells in vivo. Nat Immunol 2000;1:426-432.
    • (2000) Nat Immunol , vol.1 , pp. 426-432
    • Schluns, K.S.1    Kieper, W.C.2    Jameson, S.C.3    Lefrancois, L.4
  • 15
    • 3543099130 scopus 로고    scopus 로고
    • Helping the CD8 (+) T-cell response
    • Bevan MJ. Helping the CD8 (+) T-cell response. Nat Rev Immunol 2004;4: 595-602.
    • (2004) Nat Rev Immunol , vol.4 , pp. 595-602
    • Bevan, M.J.1
  • 16
    • 14544288632 scopus 로고    scopus 로고
    • + T-cell memory via TRAIL-mediated activation-induced cell death
    • + T-cell memory via TRAIL-mediated activation-induced cell death. Nature 2005;434:88-93.
    • (2005) Nature , vol.434 , pp. 88-93
    • Janssen, E.M.1
  • 18
    • 9144241114 scopus 로고    scopus 로고
    • Cutting edge: Transpresentation of IL-15 by bone marrow-derived cells necessitates expression of IL-15 and IL-15Ralpha by the same cells
    • Sandau MM, Schluns KS, Lefrancois L, Jameson SC. Cutting edge: transpresentation of IL-15 by bone marrow-derived cells necessitates expression of IL-15 and IL-15Ralpha by the same cells. J Immunol 2004;173:6537-6541.
    • (2004) J Immunol , vol.173 , pp. 6537-6541
    • Sandau, M.M.1    Schluns, K.S.2    Lefrancois, L.3    Jameson, S.C.4
  • 19
    • 0347382593 scopus 로고    scopus 로고
    • Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells
    • Kaech SM, Tan JT, Wherry EJ, Konieczny BT, Surh CD, Ahmed R. Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells. Nat Immunol 2003;4:1191-1198.
    • (2003) Nat Immunol , vol.4 , pp. 1191-1198
    • Kaech, S.M.1    Tan, J.T.2    Wherry, E.J.3    Konieczny, B.T.4    Surh, C.D.5    Ahmed, R.6
  • 21
    • 4644295842 scopus 로고    scopus 로고
    • Serine protease inhibitor 2a is a protective factor for memory T cell development
    • Liu N, et al. Serine protease inhibitor 2a is a protective factor for memory T cell development. Nat Immunol 2004;5:919-926.
    • (2004) Nat Immunol , vol.5 , pp. 919-926
    • Liu, N.1
  • 22
    • 0242410712 scopus 로고    scopus 로고
    • + T cell function by the transcription factor eomesodermin
    • + T cell function by the transcription factor eomesodermin. Science 2003;302: 1041-1043.
    • (2003) Science , vol.302 , pp. 1041-1043
    • Pearce, E.L.1
  • 23
    • 8544234990 scopus 로고    scopus 로고
    • Recent developments in the transcriptional regulation of cytolytic effector cells
    • Glimcher LH, Townsend MJ, Sullivan BM, Lord GM. Recent developments in the transcriptional regulation of cytolytic effector cells. Nat Rev Immunol 2004;4:900-911.
    • (2004) Nat Rev Immunol , vol.4 , pp. 900-911
    • Glimcher, L.H.1    Townsend, M.J.2    Sullivan, B.M.3    Lord, G.M.4
  • 24
    • 0035344050 scopus 로고    scopus 로고
    • Immunological adjuvants promote activated T cell survival via induction of bcl-3
    • Mitchell TC, et al. Immunological adjuvants promote activated T cell survival via induction of bcl-3. Nat Immunol 2001;2:397-402.
    • (2001) Nat Immunol , vol.2 , pp. 397-402
    • Mitchell, T.C.1
  • 27
    • 0035893005 scopus 로고    scopus 로고
    • Immune elimination of Leishmania major in mice: Implications for immune memory, vaccination, and reactivation disease
    • Uzonna JE, Wei G, Yurkowski D, Bretscher P. Immune elimination of Leishmania major in mice: Implications for immune memory, vaccination, and reactivation disease. J Immunol 2001;167:6967-6974.
    • (2001) J Immunol , vol.167 , pp. 6967-6974
    • Uzonna, J.E.1    Wei, G.2    Yurkowski, D.3    Bretscher, P.4
  • 28
    • 2242423605 scopus 로고    scopus 로고
    • CD4+CD25+ regulatory T cells control Leishmania major persistence and immunity
    • Belkaid Y, Piccirillo CA, Mendez S, Shevach EM, Sacks DL. CD4+CD25+ regulatory T cells control Leishmania major persistence and immunity. Nature 2002;420:502-507.
    • (2002) Nature , vol.420 , pp. 502-507
    • Belkaid, Y.1    Piccirillo, C.A.2    Mendez, S.3    Shevach, E.M.4    Sacks, D.L.5
  • 29
  • 30
    • 0346874501 scopus 로고    scopus 로고
    • Human CD8 (+) T-cell differentiation in response to viruses
    • van Lier RA, ten Berge IJ, Gamadia LE. Human CD8 (+) T-cell differentiation in response to viruses. Nat Rev Immunol 2003;3:931-939.
    • (2003) Nat Rev Immunol , vol.3 , pp. 931-939
    • Van Lier, R.A.1    Ten Berge, I.J.2    Gamadia, L.E.3
  • 31
    • 0035282444 scopus 로고    scopus 로고
    • Skewed maturation of memory HIV-specific CD8 T lymphocytes
    • Champagne P, et al. Skewed maturation of memory HIV-specific CD8 T lymphocytes. Nature 2001;410:106-111.
    • (2001) Nature , vol.410 , pp. 106-111
    • Champagne, P.1
  • 32
    • 0037383592 scopus 로고    scopus 로고
    • Viral persistence alters CD8 T-cell immunodominance and tissue distribution and results in distinct stages of functional impairment
    • Wherry EJ, Blattman JN, Murali-Krishna K, van der Most R, Ahmed R. Viral persistence alters CD8 T-cell immunodominance and tissue distribution and results in distinct stages of functional impairment. J Virol 2003;77:4911-4927.
    • (2003) J Virol , vol.77 , pp. 4911-4927
    • Wherry, E.J.1    Blattman, J.N.2    Murali-Krishna, K.3    Van Der Most, R.4    Ahmed, R.5
  • 33
    • 0027140283 scopus 로고
    • Unexpected expansions of CD8-bearing cells in old mice
    • Callahan JE, Kappler JW, Marrack P. Unexpected expansions of CD8-bearing cells in old mice. J Immunol 1993;151: 6657-6669.
    • (1993) J Immunol , vol.151 , pp. 6657-6669
    • Callahan, J.E.1    Kappler, J.W.2    Marrack, P.3
  • 34
    • 0027976958 scopus 로고
    • Clonal populations of T cells in normal elderly humans: The T cell equivalent to 'benign monoclonal gammapathy'
    • Posnett DN, Sinha R, Kabak S, Russo C. Clonal populations of T cells in normal elderly humans: The T cell equivalent to 'benign monoclonal gammapathy'. J Exp Med 1994;179:609-618.
    • (1994) J Exp Med , vol.179 , pp. 609-618
    • Posnett, D.N.1    Sinha, R.2    Kabak, S.3    Russo, C.4
  • 35
    • 0028920850 scopus 로고
    • Analysis of clonal CD8+ T cell expansions in normal individuals and patients with rheumatoid arthritis
    • Fitzgerald JE, et al. Analysis of clonal CD8+ T cell expansions in normal individuals and patients with rheumatoid arthritis. J Immunol 1995;154:3538-3547.
    • (1995) J Immunol , vol.154 , pp. 3538-3547
    • Fitzgerald, J.E.1
  • 36
    • 0036604275 scopus 로고    scopus 로고
    • Lack of antibody production following immunization in old age: Association with CD8 (+) CD28 (-) T cell clonal expansions and an imbalance in the production of Th1 and Th2 cytokines
    • Saurwein-Teissl M, et al. Lack of antibody production following immunization in old age: Association with CD8 (+) CD28 (-) T cell clonal expansions and an imbalance in the production of Th1 and Th2 cytokines. J Immunol 2002;168:5893-5899.
    • (2002) J Immunol , vol.168 , pp. 5893-5899
    • Saurwein-Teissl, M.1
  • 37
    • 0031137735 scopus 로고    scopus 로고
    • + T cell clones in elderly humans
    • + T cell clones in elderly humans. J Immunol 1997;158:4493-4499.
    • (1997) J Immunol , vol.158 , pp. 4493-4499
    • Schwab, R.1
  • 38
    • 0034283662 scopus 로고    scopus 로고
    • Age-related dysregulation in CD8 T cell homeostasis: Kinetics of a diversity loss
    • LeMaoult J, et al. Age-related dysregulation in CD8 T cell homeostasis: Kinetics of a diversity loss. J Immunol 2000;165:2367-2373.
    • (2000) J Immunol , vol.165 , pp. 2367-2373
    • LeMaoult, J.1
  • 40
    • 0035865460 scopus 로고    scopus 로고
    • + T cell clones in older mice is controlled by cytokines
    • + T cell clones in older mice is controlled by cytokines. J Immunol 2001;166:2186-2193.
    • (2001) J Immunol , vol.166 , pp. 2186-2193
    • Ku, C.C.1    Kappler, J.2    Marrack, P.3
  • 41
    • 0034052004 scopus 로고    scopus 로고
    • Functional subsets within clonally expanded CD8 (+) memory T cells in elderly humans
    • Chamberlain WD, Falta MT, Kotzin BL. Functional subsets within clonally expanded CD8 (+) memory T cells in elderly humans. Clin Immunol 2000;94:160-172.
    • (2000) Clin Immunol , vol.94 , pp. 160-172
    • Chamberlain, W.D.1    Falta, M.T.2    Kotzin, B.L.3
  • 42
    • 0037103256 scopus 로고    scopus 로고
    • Cytomegalovirus seropositivity drives the CD8 T cell repertoire toward greater clonality in healthy elderly individuals
    • Khan N, et al. Cytomegalovirus seropositivity drives the CD8 T cell repertoire toward greater clonality in healthy elderly individuals. J Immunol 2002;169:1984-1992.
    • (2002) J Immunol , vol.169 , pp. 1984-1992
    • Khan, N.1
  • 43
    • 0037825764 scopus 로고    scopus 로고
    • + T lymphocytes bearing receptors for a single dominant CMV epitope in the very old
    • + T lymphocytes bearing receptors for a single dominant CMV epitope in the very old. J Clin Immunol 2003;23:247-257.
    • (2003) J Clin Immunol , vol.23 , pp. 247-257
    • Ouyang, Q.1
  • 44
    • 0037397637 scopus 로고    scopus 로고
    • + T cells carrying receptors for an immunodominant Epstein-Barr virus (EBV) epitope is counteracted by a decreased frequency of their antigen-specific responsiveness
    • + T cells carrying receptors for an immunodominant Epstein-Barr virus (EBV) epitope is counteracted by a decreased frequency of their antigen-specific responsiveness. Mech Ageing Dev 2003;124:477-485.
    • (2003) Mech Ageing Dev , vol.124 , pp. 477-485
    • Ouyang, Q.1
  • 46
    • 3543141247 scopus 로고    scopus 로고
    • Different contribution of EBV and CMV infections in very long-term carriers to age-related alterations of CD8+ T cells
    • Vescovini R, et al. Different contribution of EBV and CMV infections in very long-term carriers to age-related alterations of CD8+ T cells. Exp Gerontol 2004;39:1233-1243.
    • (2004) Exp Gerontol , vol.39 , pp. 1233-1243
    • Vescovini, R.1
  • 47
    • 0029072177 scopus 로고
    • Oligoclonal CD8+ T cells are preferentially expanded in the CD57+ subset
    • Morley JK, Batliwalla FM, Hingorani R, Gregersen PK. Oligoclonal CD8+ T cells are preferentially expanded in the CD57+ subset. J Immunol 1995;154:6182-6190.
    • (1995) J Immunol , vol.154 , pp. 6182-6190
    • Morley, J.K.1    Batliwalla, F.M.2    Hingorani, R.3    Gregersen, P.K.4
  • 48
    • 0036080380 scopus 로고    scopus 로고
    • + T cells in aged mice
    • + T cells in aged mice. Eur J Immunol 2002;32:1650-1658.
    • (2002) Eur J Immunol , vol.32 , pp. 1650-1658
    • Li, F.1
  • 50
    • 0033554726 scopus 로고    scopus 로고
    • Two subsets of memory T lymphocytes with distinct homing potentials and effector functions
    • Sallusto F, Lenig D, Forster R, Lipp M, Lanzavecchia A. Two subsets of memory T lymphocytes with distinct homing potentials and effector functions. Nature 1999;401:708-712.
    • (1999) Nature , vol.401 , pp. 708-712
    • Sallusto, F.1    Lenig, D.2    Forster, R.3    Lipp, M.4    Lanzavecchia, A.5
  • 51
    • 2142730100 scopus 로고    scopus 로고
    • Central memory and effector memory T cell subsets: Function, generation, maintenance
    • Sallusto F, Geginat J, Lanzavecchia A. Central memory and effector memory T cell subsets: Function, generation, maintenance. Annu Rev Immunol 2004;22:745-763.
    • (2004) Annu Rev Immunol , vol.22 , pp. 745-763
    • Sallusto, F.1    Geginat, J.2    Lanzavecchia, A.3
  • 52
    • 1942542931 scopus 로고    scopus 로고
    • Ligands for L-selectin: Homing, inflammation, and beyond
    • Rosen SD. Ligands for L-selectin: Homing, inflammation, and beyond. Annu Rev Immunol 2004;22:129-156.
    • (2004) Annu Rev Immunol , vol.22 , pp. 129-156
    • Rosen, S.D.1
  • 53
    • 0038815306 scopus 로고    scopus 로고
    • CD45: A critical regulator of signaling thresholds in immune cells
    • Hermiston ML, Xu Z, Weiss A. CD45: a critical regulator of signaling thresholds in immune cells. Annu Rev Immunol 2003;21:107-137.
    • (2003) Annu Rev Immunol , vol.21 , pp. 107-137
    • Hermiston, M.L.1    Xu, Z.2    Weiss, A.3
  • 54
    • 0030691757 scopus 로고    scopus 로고
    • + T cells
    • + T cells. J Exp Med 1997;186: 1407-1418.
    • (1997) J Exp Med , vol.186 , pp. 1407-1418
    • Hamann, D.1
  • 55
    • 0027177864 scopus 로고
    • + T cells correlates with shifts in the frequencies of cell subsets defined by membrane CD44, CD45RB, 3G11, and MEL-14 expression
    • + T cells correlates with shifts in the frequencies of cell subsets defined by membrane CD44, CD45RB, 3G11, and MEL-14 expression. J Immunol 1993;151:575-587.
    • (1993) J Immunol , vol.151 , pp. 575-587
    • Ernst, D.N.1    Weigle, W.O.2    Noonan, D.J.3    McQuitty, D.N.4    Hobbs, M.V.5
  • 57
    • 1642536435 scopus 로고    scopus 로고
    • Different functional capacities of latent and lytic antigen-specific CD8 T cells in murine gammaherpesvirus infection
    • Obar JJ, Crist SG, Gondek DC, Usherwood EJ. Different functional capacities of latent and lytic antigen-specific CD8 T cells in murine gammaherpesvirus infection. J Immunol 2004;172:1213-1219.
    • (2004) J Immunol , vol.172 , pp. 1213-1219
    • Obar, J.J.1    Crist, S.G.2    Gondek, D.C.3    Usherwood, E.J.4
  • 58
    • 0031715650 scopus 로고    scopus 로고
    • + subsets
    • + subsets. Int Immunol 1998;10: 1281-1288.
    • (1998) Int Immunol , vol.10 , pp. 1281-1288
    • Wack, A.1
  • 59
    • 0035059417 scopus 로고    scopus 로고
    • Complexities of CD28/B7: CTLA-4 costimulatory pathways in autoimmunity and transplantation
    • Salomon B, Bluestone JA. Complexities of CD28/B7: CTLA-4 costimulatory pathways in autoimmunity and transplantation. Annu Rev Immunol 2001;19:225-252.
    • (2001) Annu Rev Immunol , vol.19 , pp. 225-252
    • Salomon, B.1    Bluestone, J.A.2
  • 60
    • 0036604316 scopus 로고    scopus 로고
    • Identification of naive or antigen-experienced human CD8 (+) T cells by expression of costimulation and chemokine receptors: Analysis of the human cytomegalovirus-specific CD8 (+) T cell response
    • Wills MR, Okecha G, Weekes MP, Gandhi MK, Sissons PJ, Carmichael AJ. Identification of naive or antigen-experienced human CD8 (+) T cells by expression of costimulation and chemokine receptors: Analysis of the human cytomegalovirus-specific CD8 (+) T cell response. J Immunol 2002;168:5455-5464.
    • (2002) J Immunol , vol.168 , pp. 5455-5464
    • Wills, M.R.1    Okecha, G.2    Weekes, M.P.3    Gandhi, M.K.4    Sissons, P.J.5    Carmichael, A.J.6
  • 65
    • 0036749867 scopus 로고    scopus 로고
    • A subset of CD8 memory T cells from old mice have high levels of CD28 and produce IFN-gamma
    • Ortiz-Suarez A, Miller RA. A subset of CD8 memory T cells from old mice have high levels of CD28 and produce IFN-gamma. Clin Immunol 2002;104:282-292.
    • (2002) Clin Immunol , vol.104 , pp. 282-292
    • Ortiz-Suarez, A.1    Miller, R.A.2
  • 66
    • 0037111658 scopus 로고    scopus 로고
    • Lack of proliferative capacity of human effector and memory T cells expressing killer cell lectinlike receptor G1 (KLRG1)
    • Voehringer D, Koschella M, Pircher H. Lack of proliferative capacity of human effector and memory T cells expressing killer cell lectinlike receptor G1 (KLRG1). Blood 2002;100:3698-3702.
    • (2002) Blood , vol.100 , pp. 3698-3702
    • Voehringer, D.1    Koschella, M.2    Pircher, H.3
  • 67
    • 0035666616 scopus 로고    scopus 로고
    • Expression of inhibitory 'killer cell lectin-like receptor G1' identifies unique subpopulations of effector and memory CD8 T cells
    • Beyersdorf NB, Ding X, Karp K, Hanke T. Expression of inhibitory 'killer cell lectin-like receptor G1' identifies unique subpopulations of effector and memory CD8 T cells. Eur J Immunol 2001;31:3443-3452.
    • (2001) Eur J Immunol , vol.31 , pp. 3443-3452
    • Beyersdorf, N.B.1    Ding, X.2    Karp, K.3    Hanke, T.4
  • 68
    • 0042206627 scopus 로고    scopus 로고
    • + T cells expressing the inhibitory killer cell lectin-like receptor G1 (KLRG1)
    • + T cells expressing the inhibitory killer cell lectin-like receptor G1 (KLRG1). Exp Gerontol 2003;38:911-920.
    • (2003) Exp Gerontol , vol.38 , pp. 911-920
    • Ouyang, Q.1
  • 69
    • 0037340417 scopus 로고    scopus 로고
    • Lineage relationship and protective immunity of memory CD8 T cell subsets
    • Wherry EJ, et al. Lineage relationship and protective immunity of memory CD8 T cell subsets. Nat Immunol 2003;4:225-234.
    • (2003) Nat Immunol , vol.4 , pp. 225-234
    • Wherry, E.J.1
  • 70
    • 0036109159 scopus 로고    scopus 로고
    • + T cells vary in differentiation phenotype in different persistent virus infections
    • + T cells vary in differentiation phenotype in different persistent virus infections. Nat Med 2002;8:379-385.
    • (2002) Nat Med , vol.8 , pp. 379-385
    • Appay, V.1
  • 71
    • 0032416085 scopus 로고    scopus 로고
    • Viral immune evasion due to persistence of activated T cells without effector function
    • Zajac AJ, et al. Viral immune evasion due to persistence of activated T cells without effector function. J Exp Med 1998;188:2205-2213.
    • (1998) J Exp Med , vol.188 , pp. 2205-2213
    • Zajac, A.J.1
  • 72
    • 0036078187 scopus 로고    scopus 로고
    • + T cells
    • + T cells. Nat Immunol 2002;3:558-563.
    • (2002) Nat Immunol , vol.3 , pp. 558-563
    • Ichii, H.1
  • 75
    • 0035881960 scopus 로고    scopus 로고
    • + T cell memory: Relationships between epitope specificity, cell phenotype, and immediate effector function
    • + T cell memory: Relationships between epitope specificity, cell phenotype, and immediate effector function. J Immunol 2001;167: 2019-2029.
    • (2001) J Immunol , vol.167 , pp. 2019-2029
    • Hislop, A.D.1
  • 76
    • 3242794119 scopus 로고    scopus 로고
    • Direct measurement of T cell subset kinetics in vivo in elderly men and women
    • Wallace DL, et al. Direct measurement of T cell subset kinetics in vivo in elderly men and women. J Immunol 2004;173:1787-1794.
    • (2004) J Immunol , vol.173 , pp. 1787-1794
    • Wallace, D.L.1
  • 77
    • 0037017378 scopus 로고    scopus 로고
    • Aging leads to disturbed homeostasis of memory phenotype CD8 (+) cells
    • Zhang X, Fujii H, Kishimoto H, LeRoy E, Surh CD, Sprent J. Aging leads to disturbed homeostasis of memory phenotype CD8 (+) cells. J Exp Med 2002;195:283-293.
    • (2002) J Exp Med , vol.195 , pp. 283-293
    • Zhang, X.1    Fujii, H.2    Kishimoto, H.3    LeRoy, E.4    Surh, C.D.5    Sprent, J.6
  • 78
    • 8444225681 scopus 로고    scopus 로고
    • Evidence of a novel IL-2/15Rbeta-targeted cytokine involved in homeostatic proliferation of memory CD8+ T cells
    • Kamimura D, et al. Evidence of a novel IL-2/15Rbeta-targeted cytokine involved in homeostatic proliferation of memory CD8+ T cells. J Immunol 2004;173:6041-6049.
    • (2004) J Immunol , vol.173 , pp. 6041-6049
    • Kamimura, D.1
  • 79
    • 0037372003 scopus 로고    scopus 로고
    • Epigenetic regulation of gene expression: How the genome integrates intrinsic and environmental signals
    • Jaenisch R, Bird A. Epigenetic regulation of gene expression: How the genome integrates intrinsic and environmental signals. Nat Genet 2003;33:245-254.
    • (2003) Nat Genet , vol.33 , pp. 245-254
    • Jaenisch, R.1    Bird, A.2
  • 80
    • 0025173863 scopus 로고
    • Clinical course and prognosis of the lymphoproliferative disease of granular lymphocytes. A multicenter study
    • Pandolfi F, et al. Clinical course and prognosis of the lymphoproliferative disease of granular lymphocytes. A multicenter study. Cancer 1990;65:341-348.
    • (1990) Cancer , vol.65 , pp. 341-348
    • Pandolfi, F.1
  • 81
    • 0031037361 scopus 로고    scopus 로고
    • The lympho-proliferative disease of granular lymphocytes: Updated criteria for diagnosis
    • Semenzato G, Zambello R, Starkebaum G, Oshimi K, Loughran TP Jr. The lympho-proliferative disease of granular lymphocytes: Updated criteria for diagnosis. Blood 1997;89:256-260.
    • (1997) Blood , vol.89 , pp. 256-260
    • Semenzato, G.1    Zambello, R.2    Starkebaum, G.3    Oshimi, K.4    Loughran Jr., T.P.5
  • 82
    • 0038210246 scopus 로고    scopus 로고
    • Monoclonal T-cell expansions in asymptomatic individuals and in patients with large granular leukemia consist of cytotoxic effector T cells expressing the activating CD94: NKG2C/E and NKD2D killer cell receptors
    • Bigouret V, et al. Monoclonal T-cell expansions in asymptomatic individuals and in patients with large granular leukemia consist of cytotoxic effector T cells expressing the activating CD94: NKG2C/E and NKD2D killer cell receptors. Blood 2003;101:3198-3204.
    • (2003) Blood , vol.101 , pp. 3198-3204
    • Bigouret, V.1
  • 84
    • 0036682492 scopus 로고    scopus 로고
    • Epstein-Barr virus-specific CD8 (+) T cells that re-express CD45RA are apoptosis-resistant memory cells that retain replicative potential
    • Dunne PJ, et al. Epstein-Barr virus-specific CD8 (+) T cells that re-express CD45RA are apoptosis-resistant memory cells that retain replicative potential. Blood 2002;100: 933-940.
    • (2002) Blood , vol.100 , pp. 933-940
    • Dunne, P.J.1
  • 85
    • 0037221256 scopus 로고    scopus 로고
    • + T cells with a CD62L++ (bright) phenotype accumulate in a subgroup of older adults and are associated with the maintenance of intact humoral immunity in old age
    • + T cells with a CD62L++ (bright) phenotype accumulate in a subgroup of older adults and are associated with the maintenance of intact humoral immunity in old age. J Immunol 2003;170:613-619.
    • (2003) J Immunol , vol.170 , pp. 613-619
    • Schwaiger, S.1    Wolf, A.M.2    Robatscher, P.3    Jenewein, B.4    Grubeck-Loebenstein, B.5
  • 86
    • 9244265523 scopus 로고    scopus 로고
    • Age-related CD8 T cell clonal expansions constrict CD8 T cell repertoire and have the potential to impair immune defense
    • Messaoudi I, Lemaoult J, Guevara-Patino JA, Metzner BM, Nikolich-Zugich J. Age-related CD8 T cell clonal expansions constrict CD8 T cell repertoire and have the potential to impair immune defense. J Exp Med 2004;200:1347-1358.
    • (2004) J Exp Med , vol.200 , pp. 1347-1358
    • Messaoudi, I.1    Lemaoult, J.2    Guevara-Patino, J.A.3    Metzner, B.M.4    Nikolich-Zugich, J.5
  • 87
    • 0029087314 scopus 로고
    • Characterization of diverse primary herpes simplex virus type 1 gB-specific cytotoxic T-cell response showing a preferential v beta bias
    • Cose SC, Kelly JM, Carbone FR. Characterization of diverse primary herpes simplex virus type 1 gB-specific cytotoxic T-cell response showing a preferential v beta bias. J Virol 1995;69:5849-5852.
    • (1995) J Virol , vol.69 , pp. 5849-5852
    • Cose, S.C.1    Kelly, J.M.2    Carbone, F.R.3
  • 88
    • 0032865673 scopus 로고    scopus 로고
    • The cytotoxic T-cell response to herpes simplex virus type 1 infection of C57BL/6 mice is almost entirely directed against a single immunodominant determinant
    • Wallace ME, Keating R, Heath WR, Carbone FR. The cytotoxic T-cell response to herpes simplex virus type 1 infection of C57BL/6 mice is almost entirely directed against a single immunodominant determinant. J Virol 1999;73:7619-7626.
    • (1999) J Virol , vol.73 , pp. 7619-7626
    • Wallace, M.E.1    Keating, R.2    Heath, W.R.3    Carbone, F.R.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.