EBV-specific CD8+ T cell memory: Relationships between epitope specificity, cell phenotype, and immediate effector function

Journal of Immunology

Volumn 167, Issue 4, 2001, Pages 2019-2029

  Hislop, A D ^a   Gudgeon, N H ^a   Callan, M F C ^a   Fazou, C ^a   Hasegawa, H ^a   Salmon, M ^a   Rickinson, A B ^a  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CD27 ANTIGEN; CD28 ANTIGEN; CD38 ANTIGEN; CD45 ANTIGEN; CD56 ANTIGEN; CD69 ANTIGEN; CD8 ANTIGEN; CHEMOKINE RECEPTOR; CHEMOKINE RECEPTOR CCR7; CYTOKINE; EPITOPE; EPSTEIN BARR VIRUS ANTIGEN; GAMMA INTERFERON; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANTIGEN EXPRESSION; ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; CYTOTOXICITY; EFFECTOR CELL; EPSTEIN BARR VIRUS; HUMAN; HUMAN CELL; LYMPHOCYTE CULTURE; MEMORY CELL; MOLECULAR RECOGNITION; NORMAL HUMAN; PHENOTYPE; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION; T LYMPHOCYTE SUBPOPULATION; VIRUS INFECTION;

EID: 0035881960     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.167.4.2019     Document Type: Article

References (42)

1. Immunological memory and protective immunity: Understanding their relation
2. Selecting and maintaining a diverse T cell repertoire
3. + T cells during the primary immune response to Epstein-Barr virus in vivo
4. + subsets in acute Epstein-Barr virus infection: Comparison with chronic human immunodeficiency virus disease
5. + T cell subsets during acute Epstein-Barr and human immunodeficiency virus infections in humans
6. + T cells contain cells with high levels of lymphocyte function-associated antigen-1 expression, a phenotype of primed T cells
7. + T cells
8. + T cells: Effector T cells
9. + pool with distinct phenotypic and migratory characteristics
10. - human T cells
11. CD28-lymphocytes T antigenic and functional properties
12. - cytotoxic effector clones
13. + T cells expressing HLA-DR and CD28 show telomerase activity and are distinct from cytolytic effector T cells
14. Two subsets of memory T lymphocytes with distinct homing potentials and effector functions
15. Phenotypic analysis of antigen-specific T lymphocytes
16. + memory T cells
17. + T cell frequencies by flow cytometry: Evidence for a novel, antigen-specific homeostatic mechanism in HIV-associated immunodeficiency
18. Human cytotoxic T lymphocyte responses to Epstein-Barr virus infection
19. Epitope focusing in the primary cytotoxic T-cell response to Epstein-Barr virus and its relationship to T-cell memory
20. Immediate early and early lyric cycle proteins are frequent targets of the Epstein-Barr virus-induced cytotoxic T cell response
21. + T cells specific for EBV in healthy virus carriers
22. + T cells produce antiviral cytokines but are impaired in cytolytic function
23. T cell response to Epstein-Barr virus transactivators in chronic rheumatoid arthritis
24. A global appraisal of immunodominant CD8 T cell responses to Epstein-Barr virus and cytomegalovirus by bulk screening
25. HLA A2.1-restricted cytotoxic T cells recognizing a range of Epstein-Barr virus isolates through a defined epitope in latent membrane protein LMP2
26. Specific cytotoxic T lymphocytes recognize the immediate-early transactivator Zta of Epstein-Barr virus
27. An Epstein-Barr virus-specific cytotoxic T cell epitope in EBV nuclear antigen 3 (EBNA 3)
28. Five new cytotoxic T cell epitopes identified within Epstein-Barr virus nuclear antigen 3
29. Changing patterns of dominant TCR usage with maturation of an EBV-specific cytotoxic T cell response
30. Increased chemokine receptor CCR7/EBII expression enhances the infiltration of lymphoid organs by adult T-cell leukemia cells
31. + T cells closely correlates with CD56 surface expression
32. + T lymphocytes in healthy seropositive donors
33. + memory T cell subsets in persistent EBV infection are differentiated by migratory receptor expression
34. + T lymphocytes in Epstein-Barr virus-induced infectious mononucleosis
35. Evidence for differential expression of CD45 isoforms by precursors for memory-dependent and independent cytotoxic responses: Human CD8 memory CTLp selectively express CD45RO (UCHL1)
36. A functional link for major TCR expansions in healthy adults caused by persistent Epstein-Barr virus infection
37. + T cells of HIV-seropositive patients
38. Development of Epstein-Barr virus-specific memory T cell receptor cłonotypes in acute infectious mononucleosis
39. + T cell memory in vivo
40. + T cells comprise both naive and memory cells
41. + T cells contain greatly expanded functional virus-specific memory CTL clones
42. pos subsets defined by CD57, CD27, and CD45 isoforms