-
1
-
-
0842265974
-
Regulation of RNA polymerase II transcription by sequence-specific DNA binding factors
-
Kadonaga, J. T. Regulation of RNA polymerase II transcription by sequence-specific DNA binding factors. Cell 116, 247-257 (2004). This review provides a general overview of the control of gene expression by transcription factors.
-
(2004)
Cell
, vol.116
, pp. 247-257
-
-
Kadonaga, J.T.1
-
3
-
-
0242410712
-
+ T cell function by the transcription factor Eomesodermin
-
+ T cells, driving effector function and IFN-γ production.
-
(2003)
Science
, vol.302
, pp. 1041-1043
-
-
Pearce, E.L.1
-
4
-
-
1842785209
-
T-bet regulates the terminal maturation and homeostasis of NK and Vα14i NKT cells
-
-/- mice. The NK-cell defect was partial and mostly developmental, whereas the Vα14i NKT-cell defect was more profound. This difference might be explained by the expression of EOMES by NK cells but not Vα14i NKT cells.
-
(2004)
Immunity
, vol.20
, pp. 477-494
-
-
Townsend, M.J.1
-
5
-
-
0034677646
-
H1 lineage commitment
-
H1 lineage commitment. Cell 100, 655-669 (2000).
-
(2000)
Cell
, vol.100
, pp. 655-669
-
-
Szabo, S.J.1
-
9
-
-
0027464928
-
Immune response in mice that lack the interferon-γ receptor
-
Huang, S. et al. Immune response in mice that lack the interferon-γ receptor. Science 259, 1742-1745 (1993).
-
(1993)
Science
, vol.259
, pp. 1742-1745
-
-
Huang, S.1
-
10
-
-
0032493299
-
Targeted disruption of the interferon-γ receptor 2 gene results in severe immune defects in mice
-
Lu, B. et al. Targeted disruption of the interferon-γ receptor 2 gene results in severe immune defects in mice. Proc. Natl Acad. Sci. USA 95, 8233-8238 (1998).
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 8233-8238
-
-
Lu, B.1
-
11
-
-
0030890586
-
Cellular responses to interferon-γ
-
Boehm, U., Klamp, T., Groot, M. & Howard, J. C. Cellular responses to interferon-γ. Annu. Rev. Immunol. 15, 749-795 (1997).
-
(1997)
Annu. Rev. Immunol.
, vol.15
, pp. 749-795
-
-
Boehm, U.1
Klamp, T.2
Groot, M.3
Howard, J.C.4
-
12
-
-
0031919849
-
Jaks and STATs: Biological implications
-
Leonard, W. J. & O'Shea, J. J. Jaks and STATs: biological implications. Annu. Rev. Immunol. 16, 293-322 (1998).
-
(1998)
Annu. Rev. Immunol.
, vol.16
, pp. 293-322
-
-
Leonard, W.J.1
O'Shea, J.J.2
-
13
-
-
0029732843
-
The proximal regulatory element of the interferon-γ promoter mediates selective expression in T cells
-
Penix, L. A. et al. The proximal regulatory element of the interferon-γ promoter mediates selective expression in T cells. J. Biol. Chem. 271, 31964-31972 (1996).
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 31964-31972
-
-
Penix, L.A.1
-
14
-
-
0031035635
-
Differential transcription directed by discrete γ interferon promoter elements in naive and memory (effector) CD4 T cells and CD8 T cells
-
Aune, T. M., Penix, L. A., Rincon, M. R. & Flavell, R. A. Differential transcription directed by discrete γ interferon promoter elements in naive and memory (effector) CD4 T cells and CD8 T cells. Mol. Cell. Biol. 17, 199-208 (1997).
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 199-208
-
-
Aune, T.M.1
Penix, L.A.2
Rincon, M.R.3
Flavell, R.A.4
-
15
-
-
0029870950
-
Identification of a calcium-inducible, cyclosporine sensitive element in the IFN-γ promoter that is a potential NFAT binding site
-
Campbell, P. M., Pimm, J., Ramassar, V. & Halloran, P. F. Identification of a calcium-inducible, cyclosporine sensitive element in the IFN-γ promoter that is a potential NFAT binding site. Transplantation 61, 933-939 (1996).
-
(1996)
Transplantation
, vol.61
, pp. 933-939
-
-
Campbell, P.M.1
Pimm, J.2
Ramassar, V.3
Halloran, P.F.4
-
16
-
-
0032567436
-
The roles of nuclear factor of activated T cells and ying-yang 1 in activation-induced expression of the interferon-γ promoter in T cells
-
Sweetser, M. T. et al. The roles of nuclear factor of activated T cells and ying-yang 1 in activation-induced expression of the interferon-γ promoter in T cells. J. Biol. Chem. 273, 34775-34783 (1998).
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 34775-34783
-
-
Sweetser, M.T.1
-
17
-
-
0030613857
-
Interaction of NF-κB and NFAT with the interferon-γ promoter
-
Sica, A. et al. Interaction of NF-κB and NFAT with the interferon-γ promoter. J. Biol. Chem. 272, 30412-30420 (1997).
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 30412-30420
-
-
Sica, A.1
-
18
-
-
0032711223
-
Preferential role for NF-κB/Rel signaling in the type 1 but not type 2 T cell-dependent immune response in vivo
-
Aronica, M. A. et al. Preferential role for NF-κB/Rel signaling in the type 1 but not type 2 T cell-dependent immune response in vivo. J. Immunol. 163, 5116-5124 (1999).
-
(1999)
J. Immunol.
, vol.163
, pp. 5116-5124
-
-
Aronica, M.A.1
-
19
-
-
0036217977
-
Lymphocyte-mediated cytotoxicity
-
Russell, J. H. & Ley, T. J. Lymphocyte-mediated cytotoxicity. Annu. Rev. Immunol. 20, 323-370 (2002). This is an excellent review that provides an overview of all known cytotoxic mechanisms.
-
(2002)
Annu. Rev. Immunol.
, vol.20
, pp. 323-370
-
-
Russell, J.H.1
Ley, T.J.2
-
20
-
-
0141506101
-
Identification of cooperative monomeric Brachyury sites conferring T-bet responsiveness to the proximal IFN-γ promoter
-
Cho, J. Y., Grigura, V., Murphy, T. L. & Murphy, K. Identification of cooperative monomeric Brachyury sites conferring T-bet responsiveness to the proximal IFN-γ promoter. Int. Immunol. 15, 1149-1160 (2003).
-
(2003)
Int. Immunol.
, vol.15
, pp. 1149-1160
-
-
Cho, J.Y.1
Grigura, V.2
Murphy, T.L.3
Murphy, K.4
-
21
-
-
1042278131
-
A distal enhancer in the interferon-γ (IFN-γ) locus revealed by genome sequence comparison
-
Lee, D. U., Avni, O., Chen, L. & Rao, A. A distal enhancer in the interferon-γ (IFN-γ) locus revealed by genome sequence comparison. J. Biol. Chem. 279, 4802-4810 (2004).
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 4802-4810
-
-
Lee, D.U.1
Avni, O.2
Chen, L.3
Rao, A.4
-
22
-
-
0035910037
-
T-bet is rapidly induced by interferon-γ in lymphoid and myeloid cells
-
Lighvani, A. A. et al. T-bet is rapidly induced by interferon-γ in lymphoid and myeloid cells. Proc. Natl Acad. Sci. USA 98, 15137-15142 (2001).
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 15137-15142
-
-
Lighvani, A.A.1
-
25
-
-
2442509626
-
T-bet controls autoaggressive CD8 lymphocyte responses in type 1 diabetes
-
Juedes, A. E., Rodrigo, E., Togher, L., Glimcher, L. H. & von Herrath, M. G. T-bet controls autoaggressive CD8 lymphocyte responses in type 1 diabetes. J. Exp. Med. 199, 1153-1162 (2004).
-
(2004)
J. Exp. Med.
, vol.199
, pp. 1153-1162
-
-
Juedes, A.E.1
Rodrigo, E.2
Togher, L.3
Glimcher, L.H.4
Von Herrath, M.G.5
-
26
-
-
0039706410
-
Crystallographic structure of the T domain-DNA complex of the Brachyury transcription factor
-
Muller, C. W. & Herrmann, B. G. Crystallographic structure of the T domain-DNA complex of the Brachyury transcription factor. Nature 389, 884-888 (1997).
-
(1997)
Nature
, vol.389
, pp. 884-888
-
-
Muller, C.W.1
Herrmann, B.G.2
-
28
-
-
13344282731
-
Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway
-
Meraz, M. A. et al. Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway. Cell 84, 431-442 (1996).
-
(1996)
Cell
, vol.84
, pp. 431-442
-
-
Meraz, M.A.1
-
29
-
-
18744398397
-
Differential requirements for Runx proteins in CD4 repression and epigenetic silencing during T lymphocyte development
-
Taniuchi, I. et al. Differential requirements for Runx proteins in CD4 repression and epigenetic silencing during T lymphocyte development. Cell 111, 621-633 (2002).
-
(2002)
Cell
, vol.111
, pp. 621-633
-
-
Taniuchi, I.1
-
30
-
-
0033023431
-
c-Rel is crucial for lymphocyte proliferation but dispensable for T cell effector function
-
Liou, H. C. et al. c-Rel is crucial for lymphocyte proliferation but dispensable for T cell effector function. Int. Immunol. 11, 361-371 (1999).
-
(1999)
Int. Immunol.
, vol.11
, pp. 361-371
-
-
Liou, H.C.1
-
31
-
-
0037711333
-
What does it take to make a natural killer?
-
Colucci, F., Caligiuri, M. A. & Di Santo, J. P. What does it take to make a natural killer? Nature Rev. Immunol. 3, 413-425 (2003).
-
(2003)
Nature Rev. Immunol.
, vol.3
, pp. 413-425
-
-
Colucci, F.1
Caligiuri, M.A.2
Di Santo, J.P.3
-
32
-
-
0033009888
-
Natural killer cells in antiviral defense: Function and regulation by innate cytokines
-
Biron, C. A., Nguyen, K. B., Pien, G. C., Cousens, L. P. & Salazar-Mather, T. P. Natural killer cells in antiviral defense: function and regulation by innate cytokines. Annu. Rev. Immunol. 17, 189-220 (1999).
-
(1999)
Annu. Rev. Immunol.
, vol.17
, pp. 189-220
-
-
Biron, C.A.1
Nguyen, K.B.2
Pien, G.C.3
Cousens, L.P.4
Salazar-Mather, T.P.5
-
33
-
-
0037716818
-
Natural killer cell receptor signaling
-
Lanier, L. L. Natural killer cell receptor signaling. Curr. Opin. Immunol. 15, 308-314 (2003).
-
(2003)
Curr. Opin. Immunol.
, vol.15
, pp. 308-314
-
-
Lanier, L.L.1
-
34
-
-
0033523620
-
Inhibitory receptors alter natural killer cell interactions with target cells yet allow simultaneous killing of susceptible targets
-
Eriksson, M. et al. Inhibitory receptors alter natural killer cell interactions with target cells yet allow simultaneous killing of susceptible targets. J. Exp. Med. 190, 1005-1012 (1999).
-
(1999)
J. Exp. Med.
, vol.190
, pp. 1005-1012
-
-
Eriksson, M.1
-
35
-
-
0034330547
-
Pivotal role of phosphoinositide-3 kinase in regulation of cytotoxicity in natural killer cells
-
Jiang, K. et al. Pivotal role of phosphoinositide-3 kinase in regulation of cytotoxicity in natural killer cells. Nature Immunol. 1, 419-425 (2000).
-
(2000)
Nature Immunol.
, vol.1
, pp. 419-425
-
-
Jiang, K.1
-
36
-
-
0036533651
-
Syk regulation of phosphoinositide 3-kinase-dependent NK cell function
-
Jiang, K. et al. Syk regulation of phosphoinositide 3-kinase-dependent NK cell function. J. Immunol. 168, 3155-3164 (2002).
-
(2002)
J. Immunol.
, vol.168
, pp. 3155-3164
-
-
Jiang, K.1
-
37
-
-
0037080348
-
UL16-binding proteins, novel MHC class I-related proteins, bind to NKG2D and activate multiple signaling pathways in primary NK cells
-
Sutherland, C. L. et al. UL16-binding proteins, novel MHC class I-related proteins, bind to NKG2D and activate multiple signaling pathways in primary NK cells. J. Immunol. 168, 671-679 (2002).
-
(2002)
J. Immunol.
, vol.168
, pp. 671-679
-
-
Sutherland, C.L.1
-
38
-
-
0037600740
-
NKG2D-DAP10 triggers human NK cell-mediated killing via a Syk-independent regulatory pathway
-
Billadeau, D. D., Upshaw, J. L., Schoon, R. A., Dick, C. J. & Leibson, P. J. NKG2D-DAP10 triggers human NK cell-mediated killing via a Syk-independent regulatory pathway. Nature Immunol. 4, 557-564 (2003).
-
(2003)
Nature Immunol.
, vol.4
, pp. 557-564
-
-
Billadeau, D.D.1
Upshaw, J.L.2
Schoon, R.A.3
Dick, C.J.4
Leibson, P.J.5
-
39
-
-
0036079077
-
In vivo developmental stages in murine natural killer cell maturation
-
Kim, S. et al. In vivo developmental stages in murine natural killer cell maturation. Nature Immunol. 3, 523-528 (2002).
-
(2002)
Nature Immunol.
, vol.3
, pp. 523-528
-
-
Kim, S.1
-
40
-
-
0030498975
-
Selective defects in the development of the fetal and adult lymphoid system in mice with an Ikaros null mutation
-
Wang, J. H. et al. Selective defects in the development of the fetal and adult lymphoid system in mice with an Ikaros null mutation. Immunity 5, 537-549 (1996).
-
(1996)
Immunity
, vol.5
, pp. 537-549
-
-
Wang, J.H.1
-
41
-
-
0032191918
-
The Ets-1 transcription factor is required for the development of natural killer cells in mice
-
Barton, K. et al. The Ets-1 transcription factor is required for the development of natural killer cells in mice. Immunity 9, 555-563 (1998).
-
(1998)
Immunity
, vol.9
, pp. 555-563
-
-
Barton, K.1
-
42
-
-
18644379642
-
The ETS protein MEF plays a critical role in perforin gene expression and the development of natural killer and NK-T cells
-
Lacorazza, H. D. et al. The ETS protein MEF plays a critical role in perforin gene expression and the development of natural killer and NK-T cells. Immunity 17, 437-449 (2002). This paper shows that the ETS-family transcription factor MEF directly regulates the perforin gene, in addition to being an important factor for NK- and NKT-cell development.
-
(2002)
Immunity
, vol.17
, pp. 437-449
-
-
Lacorazza, H.D.1
-
43
-
-
0034617994
-
Deficiency in the transcription factor interferon regulatory factor (IRF)-2 leads to severely compromised development of natural killer and T helper type 1 cells
-
Lohoff, M. et al. Deficiency in the transcription factor interferon regulatory factor (IRF)-2 leads to severely compromised development of natural killer and T helper type 1 cells. J. Exp. Med. 192, 325-336 (2000).
-
(2000)
J. Exp. Med.
, vol.192
, pp. 325-336
-
-
Lohoff, M.1
-
44
-
-
0035353208
-
Differential requirement for the transcription factor PU.1 in the generation of natural killer cells versus B and T cells
-
Colucci, F. et al. Differential requirement for the transcription factor PU.1 in the generation of natural killer cells versus B and T cells. Blood 97, 2625-2632 (2001).
-
(2001)
Blood
, vol.97
, pp. 2625-2632
-
-
Colucci, F.1
-
45
-
-
10744221544
-
GATA-3 promotes maturation, IFN-γ production, and liver-specific homing of NK Cells
-
Samson, S. I. et al. GATA-3 promotes maturation, IFN-γ production, and liver-specific homing of NK Cells. Immunity 19, 701-711 (2003).
-
(2003)
Immunity
, vol.19
, pp. 701-711
-
-
Samson, S.I.1
-
46
-
-
0033602163
-
Development of peripheral lymphoid organs and natural killer cells depends on the helix-loop-helix inhibitor Id2
-
Yokota, Y. et al. Development of peripheral lymphoid organs and natural killer cells depends on the helix-loop-helix inhibitor Id2. Nature 397, 702-706 (1999).
-
(1999)
Nature
, vol.397
, pp. 702-706
-
-
Yokota, Y.1
-
47
-
-
0035313444
-
Inhibitory effect on natural killer activity of microphthalmia transcription factor encoded by the mutant mi allele of mice
-
Ito, A. et al. Inhibitory effect on natural killer activity of microphthalmia transcription factor encoded by the mutant mi allele of mice. Blood 97, 2075-2083 (2001).
-
(2001)
Blood
, vol.97
, pp. 2075-2083
-
-
Ito, A.1
-
48
-
-
0033458015
-
Impairment of natural killer cytotoxic activity and interferon γ production in CCAAT/enhancer binding protein γ-deficient mice
-
Kaisho, T. et al. Impairment of natural killer cytotoxic activity and interferon γ production in CCAAT/enhancer binding protein γ-deficient mice. J. Exp. Med. 190, 1573-1582 (1999).
-
(1999)
J. Exp. Med.
, vol.190
, pp. 1573-1582
-
-
Kaisho, T.1
-
49
-
-
0036259559
-
Deficient natural killer cell cytotoxicity in patients with IKK-γ/NEMO mutations
-
Orange, J. S. et al. Deficient natural killer cell cytotoxicity in patients with IKK-γ/NEMO mutations. J. Clin. Invest. 109, 1501-1509 (2002).
-
(2002)
J. Clin. Invest.
, vol.109
, pp. 1501-1509
-
-
Orange, J.S.1
-
50
-
-
0035884974
-
Human NKT cells mediate antitumor cytotoxicity directly by recognizing target cell CD1d with bound ligand or indirectly by producing IL-2 to activate NK cells
-
Metelitsa, L. S. et al. Human NKT cells mediate antitumor cytotoxicity directly by recognizing target cell CD1d with bound ligand or indirectly by producing IL-2 to activate NK cells. J. Immunol. 167, 3114-3122 (2001).
-
(2001)
J. Immunol.
, vol.167
, pp. 3114-3122
-
-
Metelitsa, L.S.1
-
51
-
-
0030613856
-
Requirement for Vα14 NKT cells in IL-12-mediated rejection of tumors
-
Cui, J. et al. Requirement for Vα14 NKT cells in IL-12-mediated rejection of tumors. Science 278, 1623-1626 (1997).
-
(1997)
Science
, vol.278
, pp. 1623-1626
-
-
Cui, J.1
-
52
-
-
0036676974
-
The unconventional lifestyle of NKT cells
-
Kronenberg, M. & Gapin, L. The unconventional lifestyle of NKT cells. Nature Rev. Immunol. 2, 557-568 (2002).
-
(2002)
Nature Rev. Immunol.
, vol.2
, pp. 557-568
-
-
Kronenberg, M.1
Gapin, L.2
-
53
-
-
0037134054
-
A thymic precursor to the NK T cell lineage
-
Benlagha, K., Kyin, T., Beavis, A., Teyton, L. & Bendelac, A. A thymic precursor to the NK T cell lineage. Science 296, 553-555 (2002).
-
(2002)
Science
, vol.296
, pp. 553-555
-
-
Benlagha, K.1
Kyin, T.2
Beavis, A.3
Teyton, L.4
Bendelac, A.5
-
54
-
-
0034653452
-
The Ets1 transcription factor is required for the development of NK T cells in mice
-
Walunas, T. L., Wang, B., Wang, C. R. & Leiden, J. M. The Ets1 transcription factor is required for the development of NK T cells in mice. J. Immunol. 164, 2857-2860 (2000).
-
(2000)
J. Immunol.
, vol.164
, pp. 2857-2860
-
-
Walunas, T.L.1
Wang, B.2
Wang, C.R.3
Leiden, J.M.4
-
55
-
-
0037059462
-
H1 lineage commitment and IFN-γ production in CD4 and CD8 T cells
-
H1 lineage commitment and IFN-γ production in CD4 and CD8 T cells. Science 295, 338-342 (2002).
-
(2002)
Science
, vol.295
, pp. 338-342
-
-
Szabo, S.J.1
-
56
-
-
0038725690
-
The ABCs of granule-mediated cytotoxicity: New weapons in the arsenal
-
Lieberman, J. The ABCs of granule-mediated cytotoxicity: new weapons in the arsenal. Nature Rev. Immunol. 3, 361-370 (2003). This is a comprehensive review of cell-killing mechanisms, with a focus on granzyme- and perforin-dependent pathways.
-
(2003)
Nature Rev. Immunol.
, vol.3
, pp. 361-370
-
-
Lieberman, J.1
-
57
-
-
0033662433
-
Apo2L/TRAIL-dependent recruitment of endogenous FADD and caspase-8 to death receptors 4 and 5
-
Kischkel, F. C. et al. Apo2L/TRAIL-dependent recruitment of endogenous FADD and caspase-8 to death receptors 4 and 5. Immunity 12, 611-620 (2000).
-
(2000)
Immunity
, vol.12
, pp. 611-620
-
-
Kischkel, F.C.1
-
58
-
-
0033667778
-
FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2
-
Sprick, M. R. et al. FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2. Immunity 12, 599-609 (2000).
-
(2000)
Immunity
, vol.12
, pp. 599-609
-
-
Sprick, M.R.1
-
59
-
-
0034880940
-
Concerted action of the FasL/Fas and perforin/granzyme A and B pathways is mandatory for the development of early viral hepatitis but not for recovery from viral infection
-
Balkow, S. et al. Concerted action of the FasL/Fas and perforin/granzyme A and B pathways is mandatory for the development of early viral hepatitis but not for recovery from viral infection. J. Virol. 75, 8781-8791 (2001).
-
(2001)
J. Virol.
, vol.75
, pp. 8781-8791
-
-
Balkow, S.1
-
60
-
-
0037261142
-
Concerted action of perforin and granzymes is critical for the elimination of Trypanosoma cruzi from mouse tissues, but prevention of early host death is in addition dependent on the FasL/Fas pathway
-
Muller, U. et al. Concerted action of perforin and granzymes is critical for the elimination of Trypanosoma cruzi from mouse tissues, but prevention of early host death is in addition dependent on the FasL/Fas pathway. Eur. J. Immunol. 33, 70-78 (2003). References 59 and 60 describe studies that used gene-deficient mice to determine the relative contributions to cytotoxicity of the FAS-FASL pathway and the granule-exocytosis pathway.
-
(2003)
Eur. J. Immunol.
, vol.33
, pp. 70-78
-
-
Muller, U.1
-
61
-
-
0026687790
-
Structure and function of the murine perforin promoter and upstream region. Reciprocal gene activation or silencing in perforin positive and negative cells
-
Lichtenheld, M. G. & Podack, E. R. Structure and function of the murine perforin promoter and upstream region. Reciprocal gene activation or silencing in perforin positive and negative cells. J. Immunol. 149, 2619-2626 (1992).
-
(1992)
J. Immunol.
, vol.149
, pp. 2619-2626
-
-
Lichtenheld, M.G.1
Podack, E.R.2
-
62
-
-
0031568648
-
Non-killer cell-specific transcription factors silence the perforin promoter
-
Zhang, Y. & Lichtenheld, M. G. Non-killer cell-specific transcription factors silence the perforin promoter. J. Immunol. 158, 1734-1741 (1997).
-
(1997)
J. Immunol.
, vol.158
, pp. 1734-1741
-
-
Zhang, Y.1
Lichtenheld, M.G.2
-
63
-
-
0028314460
-
Use of the 5′-flanking region of the mouse perforin gene to express human Fcγ receptor I in cytotoxic T lymphocytes
-
Smyth, M. J., Kershaw, M. H., Hulett, M. D., McKenzie, I. F. & Trapani, J. A. Use of the 5′-flanking region of the mouse perforin gene to express human Fcγ receptor I in cytotoxic T lymphocytes. J. Leukoc. Biol. 55, 514-522 (1994).
-
(1994)
J. Leukoc. Biol.
, vol.55
, pp. 514-522
-
-
Smyth, M.J.1
Kershaw, M.H.2
Hulett, M.D.3
McKenzie, I.F.4
Trapani, J.A.5
-
64
-
-
0037187016
-
An intronic silencer of the mouse perforin gene
-
Youn, B. S., Lim, C. L., Shin, M. K., Hill, J. M. & Kwon, B. S. An intronic silencer of the mouse perforin gene. Mol. Cells 13, 61-68 (2002).
-
(2002)
Mol. Cells
, vol.13
, pp. 61-68
-
-
Youn, B.S.1
Lim, C.L.2
Shin, M.K.3
Hill, J.M.4
Kwon, B.S.5
-
65
-
-
0027495664
-
Identification of a killer cell-specific regulatory element of the mouse perforin gene: An Ets-binding site-homologous motif that interacts with Ets-related proteins
-
Koizumi, H. et al. Identification of a killer cell-specific regulatory element of the mouse perforin gene: an Ets-binding site-homologous motif that interacts with Ets-related proteins. Mol. Cell. Biol. 13, 6690-6701 (1993).
-
(1993)
Mol. Cell. Biol.
, vol.13
, pp. 6690-6701
-
-
Koizumi, H.1
-
66
-
-
0030587880
-
A critical role of Sp1- and Ets-related transcription factors in maintaining CTL-specific expression of the mouse perforin gene
-
Youn, B. S., Kim, K. K. & Kwon, B. S. A critical role of Sp1- and Ets-related transcription factors in maintaining CTL-specific expression of the mouse perforin gene. J. Immunol. 157, 3499-3509 (1996).
-
(1996)
J. Immunol.
, vol.157
, pp. 3499-3509
-
-
Youn, B.S.1
Kim, K.K.2
Kwon, B.S.3
-
67
-
-
0033105650
-
Role of a STAT binding site in the regulation of the human perforin promoter
-
Yu, C. R. et al. Role of a STAT binding site in the regulation of the human perforin promoter. J. Immunol. 162, 2785-2790 (1999).
-
(1999)
J. Immunol.
, vol.162
, pp. 2785-2790
-
-
Yu, C.R.1
-
68
-
-
0033231511
-
Interleukin 2 receptor signaling regulates the perforin gene through signal transducer and activator of transcription (Stat)5 activation of two enhancers
-
Zhang, J., Scordi, I., Smyth, M. J. & Lichtenheld, M. G. Interleukin 2 receptor signaling regulates the perforin gene through signal transducer and activator of transcription (Stat)5 activation of two enhancers. J. Exp. Med. 190, 1297-1308 (1999).
-
(1999)
J. Exp. Med.
, vol.190
, pp. 1297-1308
-
-
Zhang, J.1
Scordi, I.2
Smyth, M.J.3
Lichtenheld, M.G.4
-
70
-
-
0036402143
-
The human perforin gene is a direct target of STAT4 activated by IL-12 in NK cells
-
Yamamoto, K., Shibata, F., Miyasaka, N. & Miura, O. The human perforin gene is a direct target of STAT4 activated by IL-12 in NK cells. Biochem. Biophys. Res. Commun. 297, 1245-1252 (2002).
-
(2002)
Biochem. Biophys. Res. Commun.
, vol.297
, pp. 1245-1252
-
-
Yamamoto, K.1
Shibata, F.2
Miyasaka, N.3
Miura, O.4
-
71
-
-
0036681795
-
A role for NF-κB activation in perforin expression of NK cells upon IL-2 receptor signaling
-
Zhou, J., Zhang, J., Lichtenheld, M. G. & Meadows, G. G. A role for NF-κB activation in perforin expression of NK cells upon IL-2 receptor signaling. J. Immunol. 169, 1319-1325 (2002).
-
(2002)
J. Immunol.
, vol.169
, pp. 1319-1325
-
-
Zhou, J.1
Zhang, J.2
Lichtenheld, M.G.3
Meadows, G.G.4
-
72
-
-
0035988243
-
+ T cells during primary activation
-
+ T cells during primary activation. Int. Immunol. 14, 605-613 (2002).
-
(2002)
Int. Immunol.
, vol.14
, pp. 605-613
-
-
Kelso, A.1
-
73
-
-
5644238762
-
Differential expression of granzymes A and B in human cytotoxic lymphocyte subsets and T regulatory cells
-
6 July (doi:10.1182/blood-2004-03- 0859)
-
Grossman, W. J. et al. Differential expression of granzymes A and B in human cytotoxic lymphocyte subsets and T regulatory cells. Blood 6 July 2004 (doi:10.1182/blood-2004-03-0859).
-
(2004)
Blood
-
-
Grossman, W.J.1
-
74
-
-
0032904338
-
The 5′ flanking region of the human granzyme H gene directs expression to T/natural killer cell progenitors and lymphokine-activated killer cells in transgenic mice
-
MacIvor, D. M., Pham, C. T. & Ley, T. J. The 5′ flanking region of the human granzyme H gene directs expression to T/natural killer cell progenitors and lymphokine-activated killer cells in transgenic mice. Blood 93, 963-973 (1999).
-
(1999)
Blood
, vol.93
, pp. 963-973
-
-
MacIvor, D.M.1
Pham, C.T.2
Ley, T.J.3
-
75
-
-
0029847228
-
Long-range disruption of gene expression by a selectable marker cassette
-
Pham, C. T., MacIvor, D. M., Hug, B. A., Heusel, J. W. & Ley, T. J. Long-range disruption of gene expression by a selectable marker cassette. Proc. Natl Acad. Sci. USA 93, 13090-13095 (1996).
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 13090-13095
-
-
Pham, C.T.1
MacIvor, D.M.2
Hug, B.A.3
Heusel, J.W.4
Ley, T.J.5
-
76
-
-
0025860022
-
Structure and expression of a cluster of human hematopoietic serine protease genes found on chromosome 14q11.2
-
Heusel, J. W., Hanson, R. D., Silverman, G. A. & Lay, T. J. Structure and expression of a cluster of human hematopoietic serine protease genes found on chromosome 14q11.2. J. Biol. Chem. 266, 6152-6158 (1991).
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 6152-6158
-
-
Heusel, J.W.1
Hanson, R.D.2
Silverman, G.A.3
Lay, T.J.4
-
77
-
-
0027403270
-
A promoter element of the human serine esterase granzyme B gene controls specific transcription in activated T cells
-
Haddad, P., Wargnier, A., Bourge, J. F., Sasportes, M. & Paul, P. A promoter element of the human serine esterase granzyme B gene controls specific transcription in activated T cells. Eur. J. Immunol. 23, 625-629 (1993).
-
(1993)
Eur. J. Immunol.
, vol.23
, pp. 625-629
-
-
Haddad, P.1
Wargnier, A.2
Bourge, J.F.3
Sasportes, M.4
Paul, P.5
-
78
-
-
0029155598
-
Identification of human granzyme B promoter regulatory elements interacting with activated T-cell-specific proteins: Implication of Ikaros and CBF binding sites in promoter activation
-
Wargnier, A. et al. Identification of human granzyme B promoter regulatory elements interacting with activated T-cell-specific proteins: implication of Ikaros and CBF binding sites in promoter activation. Proc. Natl Acad. Sci. USA 92, 6930-6934 (1995).
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 6930-6934
-
-
Wargnier, A.1
-
79
-
-
0029940438
-
In vivo regulation of murine granzyme B gene transcription in activated primary T cells
-
Babichuk, C. K., Duggan, B. L. & Bleackley, R. C. In vivo regulation of murine granzyme B gene transcription in activated primary T cells. J. Biol. Chem. 271, 16485-16493 (1996).
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 16485-16493
-
-
Babichuk, C.K.1
Duggan, B.L.2
Bleackley, R.C.3
-
80
-
-
0030855489
-
Mutational analysis of the murine granzyme B gene promoter in primary T cells and a T cell clone
-
Babichuk, C. K. & Bleackley, R. C. Mutational analysis of the murine granzyme B gene promoter in primary T cells and a T cell clone. J. Biol. Chem. 272, 18564-18571 (1997).
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 18564-18571
-
-
Babichuk, C.K.1
Bleackley, R.C.2
-
81
-
-
0027518159
-
Consensus AP-1 and CRE motifs upstream from the human cytotoxic serine protease B (CSP-B/CGL-1) gene synergize to activate transcription
-
Hanson, R. D., Grisolano, J. L. & Ley, T. J. Consensus AP-1 and CRE motifs upstream from the human cytotoxic serine protease B (CSP-B/CGL-1) gene synergize to activate transcription. Blood 82, 2749-2757 (1993).
-
(1993)
Blood
, vol.82
, pp. 2749-2757
-
-
Hanson, R.D.1
Grisolano, J.L.2
Ley, T.J.3
-
82
-
-
0032567347
-
Down-regulation of human granzyme B expression by glucocorticoids. Dexamethasone inhibits binding to the Ikaros and AP-1 regulatory elements of the granzyme B promoter
-
Wargnier, A. et al. Down-regulation of human granzyme B expression by glucocorticoids. Dexamethasone inhibits binding to the Ikaros and AP-1 regulatory elements of the granzyme B promoter. J. Biol. Chem. 273, 35326-35331 (1998).
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 35326-35331
-
-
Wargnier, A.1
-
83
-
-
0032079506
-
Systematic method to obtain novel genes that are regulated by mi transcription factor: Impaired expression of granzyme B and tryptophan hydroxylase in mi/mi cultured mast cells
-
Ito, A. et al. Systematic method to obtain novel genes that are regulated by mi transcription factor: impaired expression of granzyme B and tryptophan hydroxylase in mi/mi cultured mast cells. Blood 91, 3210-3221 (1998).
-
(1998)
Blood
, vol.91
, pp. 3210-3221
-
-
Ito, A.1
-
84
-
-
0033564652
-
wh allele on phenotype of murine mast cells
-
wh allele on phenotype of murine mast cells. Blood 93, 4179-4186 (1999).
-
(1999)
Blood
, vol.93
, pp. 4179-4186
-
-
Kim, D.K.1
-
85
-
-
0024334160
-
IL-2 induces expression of serine protease enzymes and genes in natural killer and nonspecific T killer cells
-
Manyak, C. L. et al. IL-2 induces expression of serine protease enzymes and genes in natural killer and nonspecific T killer cells. J. Immunol. 142, 3707-3713 (1989).
-
(1989)
J. Immunol.
, vol.142
, pp. 3707-3713
-
-
Manyak, C.L.1
-
86
-
-
0029096189
-
IL-12 synergizes with IL-2 to induce lymphokine-activated cytotoxicity and perforin and granzyme gene expression in fresh human NK cells
-
DeBlaker-Hohe, D. F., Yamauchi, A., Yu, C. R., Horvath-Arcidiacono, J. A. & Bloom, E. T. IL-12 synergizes with IL-2 to induce lymphokine-activated cytotoxicity and perforin and granzyme gene expression in fresh human NK cells. Cell. Immunol. 165, 33-43 (1995).
-
(1995)
Cell. Immunol.
, vol.165
, pp. 33-43
-
-
DeBlaker-Hohe, D.F.1
Yamauchi, A.2
Yu, C.R.3
Horvath-Arcidiacono, J.A.4
Bloom, E.T.5
-
87
-
-
0030602187
-
Interleukin-15 induces the expression of mRNAs of cytolytic mediators and augments cytotoxic activities in primary murine lymphocytes
-
Ye, W., Young, J. D. & Liu, C. C. Interleukin-15 induces the expression of mRNAs of cytolytic mediators and augments cytotoxic activities in primary murine lymphocytes. Cell. Immunol. 174, 54-62 (1996).
-
(1996)
Cell. Immunol.
, vol.174
, pp. 54-62
-
-
Ye, W.1
Young, J.D.2
Liu, C.C.3
-
88
-
-
0032969285
-
Tumor necrosis factor receptor and Fas signaling mechanisms
-
Wallach, D. et al. Tumor necrosis factor receptor and Fas signaling mechanisms. Annu. Rev. Immunol. 17, 331-367 (1999).
-
(1999)
Annu. Rev. Immunol.
, vol.17
, pp. 331-367
-
-
Wallach, D.1
-
89
-
-
0033396491
-
Fas ligand-induced apoptosis
-
Nagata, S. Fas ligand-induced apoptosis. Annu. Rev. Genet. 33, 29-55 (1999).
-
(1999)
Annu. Rev. Genet.
, vol.33
, pp. 29-55
-
-
Nagata, S.1
-
90
-
-
0029847113
-
- functionally immature human NK cell subset that differentiates in vitro in the presence of interleukin 12
-
- functionally immature human NK cell subset that differentiates in vitro in the presence of interleukin 12. J. Exp. Med. 184, 1845-1856 (1996).
-
(1996)
J. Exp. Med.
, vol.184
, pp. 1845-1856
-
-
Bennett, I.M.1
-
91
-
-
0032447111
-
Natural killer (NK) cell-mediated cytotoxicity: Differential use of TRAIL and Fas ligand by immature and mature primary human NK cells
-
Zamai, L. et al. Natural killer (NK) cell-mediated cytotoxicity: differential use of TRAIL and Fas ligand by immature and mature primary human NK cells. J. Exp. Med. 188, 2375-2380 (1998).
-
(1998)
J. Exp. Med.
, vol.188
, pp. 2375-2380
-
-
Zamai, L.1
-
92
-
-
14844345988
-
Expression of the Fas ligand in cells of T cell lineage
-
Suda, T. et al. Expression of the Fas ligand in cells of T cell lineage. J. Immunol. 154, 3806-3813 (1995).
-
(1995)
J. Immunol.
, vol.154
, pp. 3806-3813
-
-
Suda, T.1
-
93
-
-
0031570119
-
Regulation of CD95 (Fas) ligand expression by TCR-mediated signaling events
-
Latinis, K. M. et al. Regulation of CD95 (Fas) ligand expression by TCR-mediated signaling events. J. Immunol. 158, 4602-4611 (1997).
-
(1997)
J. Immunol.
, vol.158
, pp. 4602-4611
-
-
Latinis, K.M.1
-
94
-
-
0031213797
-
+ T cells reactivated with superantigen are both more sensitive to FasL-mediated killing and express a higher level of FasL
-
+ T cells reactivated with superantigen are both more sensitive to FasL-mediated killing and express a higher level of FasL. Cell. Immunol. 179, 153-164 (1997).
-
(1997)
Cell. Immunol.
, vol.179
, pp. 153-164
-
-
Wang, J.K.1
Zhu, B.2
Ju, S.T.3
Tschopp, J.4
Marshak-Rothstein, A.5
-
95
-
-
0032194170
-
Identification of two NF-κB sites in mouse CD95 ligand (Fas ligand) promoter: Functional analysis in T cell hybridoma
-
Matsui, K., Fine, A., Zhu, B., Marshak-Rothstein, A. & Ju, S. T. Identification of two NF-κB sites in mouse CD95 ligand (Fas ligand) promoter: functional analysis in T cell hybridoma. J. Immunol. 161, 3469-3473 (1998).
-
(1998)
J. Immunol.
, vol.161
, pp. 3469-3473
-
-
Matsui, K.1
Fine, A.2
Zhu, B.3
Marshak-Rothstein, A.4
Ju, S.T.5
-
96
-
-
0032014073
-
DNA damaging agents induce expression of Fas ligand and subsequent apoptosis in T lymphocytes via the activation of NF-κB and AP-1
-
Kasibhatla, S. et al. DNA damaging agents induce expression of Fas ligand and subsequent apoptosis in T lymphocytes via the activation of NF-κB and AP-1. Mol. Cell 1, 543-551 (1998).
-
(1998)
Mol. Cell
, vol.1
, pp. 543-551
-
-
Kasibhatla, S.1
-
97
-
-
0033534465
-
Regulation of Fas-ligand expression during activation-induced cell death in T lymphocytes via nuclear factor κB
-
Kasibhatla, S., Genestier, L. & Green, D. R. Regulation of Fas-ligand expression during activation-induced cell death in T lymphocytes via nuclear factor κB. J. Biol. Chem. 274, 987-992 (1999).
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 987-992
-
-
Kasibhatla, S.1
Genestier, L.2
Green, D.R.3
-
98
-
-
0030882077
-
Proteasome regulation of Fas ligand cytotoxicity
-
Matsui, K. et al. Proteasome regulation of Fas ligand cytotoxicity. Eur. J. Immunol. 27, 2269-2278 (1997).
-
(1997)
Eur. J. Immunol.
, vol.27
, pp. 2269-2278
-
-
Matsui, K.1
-
99
-
-
0031862141
-
Cyclosporin A-sensitive transcription factor Egr-3 regulates Fas ligand expression
-
Mittelstadt, P. R. & Ashwell, J. D. Cyclosporin A-sensitive transcription factor Egr-3 regulates Fas ligand expression. Mol. Cell. Biol. 18, 3744-3751 (1998).
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 3744-3751
-
-
Mittelstadt, P.R.1
Ashwell, J.D.2
-
100
-
-
0033613847
-
Role of Egr-2 in up-regulation of Fas ligand in normal T cells and aberrant double-negative lpr and gld T cells
-
Mittelstadt, P. R. & Ashwell, J. D. Role of Egr-2 in up-regulation of Fas ligand in normal T cells and aberrant double-negative lpr and gld T cells. J. Biol. Chem. 274, 3222-3227 (1999).
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 3222-3227
-
-
Mittelstadt, P.R.1
Ashwell, J.D.2
-
101
-
-
0142091494
-
Egr family members regulate nonlymphoid expression of Fas ligand, TRAIL, and tumor necrosis factor during immune responses
-
Droin, N. M., Pinkoski, M. J., Dejardin, E. & Green, D. R. Egr family members regulate nonlymphoid expression of Fas ligand, TRAIL, and tumor necrosis factor during immune responses. Mol. Cell. Biol. 23, 7638-7647 (2003).
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 7638-7647
-
-
Droin, N.M.1
Pinkoski, M.J.2
Dejardin, E.3
Green, D.R.4
-
102
-
-
0031465970
-
Two NFAT transcription factor binding sites participate in the regulation of CD95 (Fas) ligand expression in activated human T cells
-
Latinis, K. M., Norian, L. A., Eliason, S. L. & Koretzky, G. A. Two NFAT transcription factor binding sites participate in the regulation of CD95 (Fas) ligand expression in activated human T cells. J. Biol. Chem. 272, 31427-31434 (1997).
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 31427-31434
-
-
Latinis, K.M.1
Norian, L.A.2
Eliason, S.L.3
Koretzky, G.A.4
-
103
-
-
0030002617
-
Hyperproliferation and dysregulation of IL-4 expression in NF-ATp-deficient mice
-
Hodge, M. R. et al. Hyperproliferation and dysregulation of IL-4 expression in NF-ATp-deficient mice. Immunity 4, 397-405 (1996).
-
(1996)
Immunity
, vol.4
, pp. 397-405
-
-
Hodge, M.R.1
-
105
-
-
0033712590
-
Sequential involvement of NFAT and Egr transcription factors in FasL regulation
-
Rengarajan, J. et al. Sequential involvement of NFAT and Egr transcription factors in FasL regulation. Immunity 12, 293-300 (2000).
-
(2000)
Immunity
, vol.12
, pp. 293-300
-
-
Rengarajan, J.1
-
106
-
-
0035284888
-
The class II transactivator prevents activation-induced cell death by inhibiting Fas ligand gene expression
-
Gourley, T. S. & Chang, C. H. The class II transactivator prevents activation-induced cell death by inhibiting Fas ligand gene expression. J. Immunol. 166, 2917-2921 (2001).
-
(2001)
J. Immunol.
, vol.166
, pp. 2917-2921
-
-
Gourley, T.S.1
Chang, C.H.2
-
107
-
-
0036568948
-
Aberrant expression of Fas ligand in mice deficient for the MHC class II transactivator
-
Gourley, T. S., Patel, D. R., Nickerson, K., Hong, S. C. & Chang, C. H. Aberrant expression of Fas ligand in mice deficient for the MHC class II transactivator. J. Immunol. 168, 4414-4419 (2002).
-
(2002)
J. Immunol.
, vol.168
, pp. 4414-4419
-
-
Gourley, T.S.1
Patel, D.R.2
Nickerson, K.3
Hong, S.C.4
Chang, C.H.5
-
108
-
-
0030584826
-
Fc receptor-induced expression of Fas ligand on activated NK cells facilitates cell-mediated cytotoxicity and subsequent autocrine NK cell apoptosis
-
Eischen, C. M., Schilling, J. D., Lynch, D. H., Krammer, P. H. & Leibson, P. J. Fc receptor-induced expression of Fas ligand on activated NK cells facilitates cell-mediated cytotoxicity and subsequent autocrine NK cell apoptosis. J. Immunol. 156, 2693-2699 (1996).
-
(1996)
J. Immunol.
, vol.156
, pp. 2693-2699
-
-
Eischen, C.M.1
Schilling, J.D.2
Lynch, D.H.3
Krammer, P.H.4
Leibson, P.J.5
-
109
-
-
0033557724
-
Fas ligand induction in human NK cells is regulated by redox through a calcineurin-nuclear factors of activated T cell-dependent pathway
-
Furuke, K., Shiraishi, M., Mostowski, H. S. & Bloom, E. T. Fas ligand induction in human NK cells is regulated by redox through a calcineurin-nuclear factors of activated T cell-dependent pathway. J. Immunol. 162, 1988-1993 (1999).
-
(1999)
J. Immunol.
, vol.162
, pp. 1988-1993
-
-
Furuke, K.1
Shiraishi, M.2
Mostowski, H.S.3
Bloom, E.T.4
-
110
-
-
0141481088
-
Structure/function analysis of the murine CD95L promoter reveals the identification of a novel transcriptional repressor and functional CD28 response element
-
Crist, S. A., Griffith, T. S. & Ratliff, T. L. Structure/function analysis of the murine CD95L promoter reveals the identification of a novel transcriptional repressor and functional CD28 response element. J. Biol. Chem. 278, 35950-35958 (2003).
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 35950-35958
-
-
Crist, S.A.1
Griffith, T.S.2
Ratliff, T.L.3
-
111
-
-
0034192075
-
The regulation of CD95 (Fas) ligand expression in primary T cells: Induction of promoter activation in CD95LP-Luc transgenic mice
-
Norian, L. A. et al. The regulation of CD95 (Fas) ligand expression in primary T cells: induction of promoter activation in CD95LP-Luc transgenic mice. J. Immunol. 164, 4471-4480 (2000).
-
(2000)
J. Immunol.
, vol.164
, pp. 4471-4480
-
-
Norian, L.A.1
-
112
-
-
0032589683
-
FasL promoter activation by IL-2 through SP1 and NFAT but not Egr-2 and Egr-3
-
Xiao, S. et al. FasL promoter activation by IL-2 through SP1 and NFAT but not Egr-2 and Egr-3. Eur. J. Immunol. 29, 3456-3465 (1999).
-
(1999)
Eur. J. Immunol.
, vol.29
, pp. 3456-3465
-
-
Xiao, S.1
-
113
-
-
0033583315
-
Constitutive Fas ligand gene transcription in Sertoli cells is regulated by Sp1
-
McClure, R. F., Heppelmann, C. J. & Paya, C. V. Constitutive Fas ligand gene transcription in Sertoli cells is regulated by Sp1. J. Biol. Chem. 274, 7756-7762 (1999).
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 7756-7762
-
-
McClure, R.F.1
Heppelmann, C.J.2
Paya, C.V.3
-
114
-
-
0037183972
-
Ets-1 positively regulates Fas ligand transcription via cooperative interactions with Sp1
-
Kavurma, M. M., Bobryshev, Y. & Khachigian, L. M. Ets-1 positively regulates Fas ligand transcription via cooperative interactions with Sp1. J. Biol. Chem. 277, 36244-36252 (2002).
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 36244-36252
-
-
Kavurma, M.M.1
Bobryshev, Y.2
Khachigian, L.M.3
-
115
-
-
0034609762
-
A 'non-canonical' DNA-binding element mediates the response of the Fas-ligand promoter to c-Myc
-
Kasibhatla, S., Beere, H. M., Brunner, T., Echeverri, F. & Green, D. R. A 'non-canonical' DNA-binding element mediates the response of the Fas-ligand promoter to c-Myc. Curr. Biol. 10, 1205-1208 (2000).
-
(2000)
Curr. Biol.
, vol.10
, pp. 1205-1208
-
-
Kasibhatla, S.1
Beere, H.M.2
Brunner, T.3
Echeverri, F.4
Green, D.R.5
-
116
-
-
4444372172
-
Regulation of activation-induced Fas (CD95/Apo-1) ligand expression in T cells by the cyclin B1/Cdk1 complex
-
Torgler, R. et al. Regulation of activation-induced Fas (CD95/Apo-1) ligand expression in T cells by the cyclin B1/Cdk1 complex. J. Biol. Chem. 279, 37334-37342 (2004).
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 37334-37342
-
-
Torgler, R.1
-
117
-
-
0034737732
-
Expression of Fas ligand in activated T cells is regulated by c-Myc
-
Brunner, T. et al. Expression of Fas ligand in activated T cells is regulated by c-Myc. J. Biol. Chem. 275, 9767-9772 (2000).
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 9767-9772
-
-
Brunner, T.1
-
118
-
-
0042931206
-
H1 and CTL responses: Two-signal requirement for the induction of NK cell helper function
-
H1 and CTL responses: two-signal requirement for the induction of NK cell helper function. J. Immunol. 171, 2366-2373 (2003).
-
(2003)
J. Immunol.
, vol.171
, pp. 2366-2373
-
-
Mailliard, R.B.1
-
119
-
-
0033152840
-
Perforin is a major contributor to NK cell control of tumor metastasis
-
Smyth, M. J. et al. Perforin is a major contributor to NK cell control of tumor metastasis. J. Immunol. 162, 6658-6662 (1999).
-
(1999)
J. Immunol.
, vol.162
, pp. 6658-6662
-
-
Smyth, M.J.1
-
120
-
-
0029804782
-
Decreased tumor surveillance in perforin-deficient mice
-
van den Broek, M. E. et al. Decreased tumor surveillance in perforin-deficient mice. J. Exp. Med. 184, 1781-1790 (1996).
-
(1996)
J. Exp. Med.
, vol.184
, pp. 1781-1790
-
-
Van Den Broek, M.E.1
-
121
-
-
0030014911
-
Granzyme A is critical for recovery of mice from infection with the natural cytopathic viral pathogen, eotromelia
-
Mullbacher, A. et al. Granzyme A is critical for recovery of mice from infection with the natural cytopathic viral pathogen, eotromelia. Proc. Natl Acad. Sci. USA 93, 5783-5787 (1996).
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 5783-5787
-
-
Mullbacher, A.1
-
122
-
-
0038107576
-
Granzymes A B are not essential for perforin-mediated tumor rejection
-
Smyth, M. J., Street, S. E. & Trapani, J. A. Granzymes A and B are not essential for perforin-mediated tumor rejection. J. Immunol. 171, 515-518 (2003).
-
(2003)
J. Immunol.
, vol.171
, pp. 515-518
-
-
Smyth, M.J.1
Street, S.E.2
Trapani, J.A.3
-
123
-
-
0028258577
-
Cytotoxic lymphocytes require granzyme B for the rapid induction of DNA fragmentation and apoptosis in allogeneic target cells
-
Heusel, J. W., Wesselschmidt, R. L., Shresta, S., Russell, J. H. & Ley, T. J. Cytotoxic lymphocytes require granzyme B for the rapid induction of DNA fragmentation and apoptosis in allogeneic target cells. Cell 76, 977-987 (1994).
-
(1994)
Cell
, vol.76
, pp. 977-987
-
-
Heusel, J.W.1
Wesselschmidt, R.L.2
Shresta, S.3
Russell, J.H.4
Ley, T.J.5
-
124
-
-
0028223847
-
Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand
-
Takahashi, T. et al. Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand. Cell 76, 969-976 (1994).
-
(1994)
Cell
, vol.76
, pp. 969-976
-
-
Takahashi, T.1
-
125
-
-
0041929457
-
The Fas/Fas ligand pathway is important for optimal tumor regression in a mouse model of CTL adoptive immunotherapy of experimental CMS4 lung metastases
-
Caldwell, S. A., Ryan, M. H., McDuffie, E. & Abrams, S. I. The Fas/Fas ligand pathway is important for optimal tumor regression in a mouse model of CTL adoptive immunotherapy of experimental CMS4 lung metastases. J. Immunol. 171, 2402-2412 (2003).
-
(2003)
J. Immunol.
, vol.171
, pp. 2402-2412
-
-
Caldwell, S.A.1
Ryan, M.H.2
McDuffie, E.3
Abrams, S.I.4
-
126
-
-
0027400726
-
Multiple defects of immune cell function in mice with disrupted interferon-γ genes
-
Dalton, D. K. et al. Multiple defects of immune cell function in mice with disrupted interferon-γ genes. Science 259, 1739-1742 (1993).
-
(1993)
Science
, vol.259
, pp. 1739-1742
-
-
Dalton, D.K.1
-
127
-
-
0027360333
-
An essential role for interferon-γ in resistance to Mycobacterium tuberculosis infection
-
Flynn, J. L. et al. An essential role for interferon-γ in resistance to Mycobacterium tuberculosis infection. J. Exp. Med. 178, 2249-2254 (1993).
-
(1993)
J. Exp. Med.
, vol.178
, pp. 2249-2254
-
-
Flynn, J.L.1
-
128
-
-
0027482327
-
Disseminated tuberculosis in interferon γ gene-disrupted mice
-
Cooper, A. M. et al. Disseminated tuberculosis in interferon γ gene-disrupted mice. J. Exp. Med. 178, 2243-2247 (1993).
-
(1993)
J. Exp. Med.
, vol.178
, pp. 2243-2247
-
-
Cooper, A.M.1
-
129
-
-
0030587910
-
IFN-γ plays a critical down-regulatory role in the induction and effector phase of myelin oligodendrocyte glycoprotein-induced autoimmune encephalomyelitis
-
Willenborg, D. O., Fordham, S., Bernard, C. C., Cowden, W. B. & Ramshaw, I. A. IFN-γ plays a critical down-regulatory role in the induction and effector phase of myelin oligodendrocyte glycoprotein-induced autoimmune encephalomyelitis. J. Immunol. 157, 3223-3227 (1996).
-
(1996)
J. Immunol.
, vol.157
, pp. 3223-3227
-
-
Willenborg, D.O.1
Fordham, S.2
Bernard, C.C.3
Cowden, W.B.4
Ramshaw, I.A.5
-
130
-
-
0033571331
-
IFN-γ is critical to the control of murine autoimmune encephalomyelitis and regulates both in the periphery and in the target tissue: A possible role for nitric oxide
-
Willenborg, D. O., Fordham, S. A., Staykova, M. A., Ramshaw, I. A. & Cowden, W. B. IFN-γ is critical to the control of murine autoimmune encephalomyelitis and regulates both in the periphery and in the target tissue: a possible role for nitric oxide. J. Immunol. 163, 5278-5286 (1999).
-
(1999)
J. Immunol.
, vol.163
, pp. 5278-5286
-
-
Willenborg, D.O.1
Fordham, S.A.2
Staykova, M.A.3
Ramshaw, I.A.4
Cowden, W.B.5
-
131
-
-
3142724732
-
Loss of T-bet, but not STAT1, prevents the development of experimental autoimmune encephalomyelitis
-
Bettelli, E. et al. Loss of T-bet, but not STAT1, prevents the development of experimental autoimmune encephalomyelitis. J. Exp. Med. 200, 79-87 (2004).
-
(2004)
J. Exp. Med.
, vol.200
, pp. 79-87
-
-
Bettelli, E.1
-
132
-
-
0346024088
-
+ regulatory T Cells in the absence of STAT1: Increased susceptibility to autoimmune disease
-
+ regulatory T Cells in the absence of STAT1: increased susceptibility to autoimmune disease. J. Exp. Med. 199, 25-34 (2004).
-
(2004)
J. Exp. Med.
, vol.199
, pp. 25-34
-
-
Nishibori, T.1
Tanabe, Y.2
Su, L.3
David, M.4
-
133
-
-
0032785433
-
STAT-4 mediated IL-12 signaling pathway is critical for the development of protective immunity in cutaneous leishmaniasis
-
Stamm, L. M., Satoskar, A. A., Ghosh, S. K., David, J. R. & Satoskar, A. R. STAT-4 mediated IL-12 signaling pathway is critical for the development of protective immunity in cutaneous leishmaniasis. Eur. J. Immunol. 29, 2524-2529 (1999).
-
(1999)
Eur. J. Immunol.
, vol.29
, pp. 2524-2529
-
-
Stamm, L.M.1
Satoskar, A.A.2
Ghosh, S.K.3
David, J.R.4
Satoskar, A.R.5
-
134
-
-
0037029649
-
The transcription factor T-bet regulates mucosal T cell activation in experimental colitis and Crohn's disease
-
Neurath, M. F. et al. The transcription factor T-bet regulates mucosal T cell activation in experimental colitis and Crohn's disease. J. Exp. Med. 195, 1129-1143 (2002).
-
(2002)
J. Exp. Med.
, vol.195
, pp. 1129-1143
-
-
Neurath, M.F.1
|