-
1
-
-
0034144269
-
Chemokines: A new classification system and their role in immunity
-
Zlotnik A, Yoshie O. Chemokines: a new classification system and their role in immunity. Immunity 2000; 12:121-7.
-
(2000)
Immunity
, vol.12
, pp. 121-127
-
-
Zlotnik, A.1
Yoshie, O.2
-
3
-
-
0032499260
-
Chemokines and leukocyte traffic
-
Baggiolini M. Chemokines and leukocyte traffic. Nature 1998; 392:565-8.
-
(1998)
Nature
, vol.392
, pp. 565-568
-
-
Baggiolini, M.1
-
4
-
-
0029071643
-
Chemokines and Tissue Injury
-
Furie MB, Randolph GJ. Chemokines and Tissue Injury. Am J Pathol 1995; 146:1287-301.
-
(1995)
Am J Pathol
, vol.146
, pp. 1287-1301
-
-
Furie, M.B.1
Randolph, G.J.2
-
5
-
-
0037180812
-
Points of control in inflammation
-
Nathan C. Points of control in inflammation. Nature 2002; 420:846-52.
-
(2002)
Nature
, vol.420
, pp. 846-852
-
-
Nathan, C.1
-
6
-
-
0037180757
-
Inflammation and cancer
-
Coussens LM, Werb Z. Inflammation and cancer. Nature 2002; 420:860-7.
-
(2002)
Nature
, vol.420
, pp. 860-867
-
-
Coussens, L.M.1
Werb, Z.2
-
7
-
-
0037180771
-
Inflammation in atherosclerosis
-
Libby P. Inflammation in atherosclerosis. Nature 2002; 420:868-74.
-
(2002)
Nature
, vol.420
, pp. 868-874
-
-
Libby, P.1
-
8
-
-
0028202481
-
The molecular biology of leukocyte chemoattractant receptors
-
Murphy PM. The molecular biology of leukocyte chemoattractant receptors. Annu Rev Immunol 1994; 12:593-633.
-
(1994)
Annu Rev Immunol
, vol.12
, pp. 593-633
-
-
Murphy, P.M.1
-
9
-
-
0028860268
-
Heterotrimeric G proteins: Organizers of transmembrane signals
-
Neer EJ. Heterotrimeric G proteins: organizers of transmembrane signals. Cell 1995; 80:249-57.
-
(1995)
Cell
, vol.80
, pp. 249-257
-
-
Neer, E.J.1
-
10
-
-
0041352963
-
Directional sensing requires G beta gamma-mediated PAK1 and PIX alpha-dependent activation of Cdc42
-
Li Z, Hannigan M., Mo Z, et al. Directional sensing requires G beta gamma-mediated PAK1 and PIX alpha-dependent activation of Cdc42. Cell 2003; 114:215-27.
-
(2003)
Cell
, vol.114
, pp. 215-227
-
-
Li, Z.1
Hannigan, M.2
Mo, Z.3
-
11
-
-
0032538570
-
Specific involvement of G proteins in regulation of SRF by receptors
-
Mao J, Yuan H, Xie W, Wu D. Specific involvement of G proteins in regulation of SRF by receptors. J Biol Chem 1998; 273:27118-23.
-
(1998)
J Biol Chem
, vol.273
, pp. 27118-27123
-
-
Mao, J.1
Yuan, H.2
Xie, W.3
Wu, D.4
-
12
-
-
0042354714
-
Divergent signals and cytoskeletal assemblies regulate self-organizing polarity in neutrophils
-
Xu J, Wang F, Van Keymeulen A, et al. Divergent signals and cytoskeletal assemblies regulate self-organizing polarity in neutrophils. Cell 2003; 114:201-14.
-
(2003)
Cell
, vol.114
, pp. 201-214
-
-
Xu, J.1
Wang, F.2
Van Keymeulen, A.3
-
13
-
-
0032573086
-
Specific involvement of GEF115 in activation of Rho and SRF by Gα13
-
USA
-
Mao J, Yuan H, Xie W, Wu D. Specific involvement of GEF115 in activation of Rho and SRF by Gα13. Proc Natl Acad Sci USA 1998; 95:12973-6.
-
(1998)
Proc Natl Acad Sci
, vol.95
, pp. 12973-12976
-
-
Mao, J.1
Yuan, H.2
Xie, W.3
Wu, D.4
-
14
-
-
0032569051
-
P115 RhoGEF, a GTPase activating protein for Gα12 and Gα13
-
Kozasa T, Jiang XJ, Hart MJ, et al. P115 RhoGEF, a GTPase activating protein for Gα12 and Gα13. Science 1998; 280:2109-11.
-
(1998)
Science
, vol.280
, pp. 2109-2111
-
-
Kozasa, T.1
Jiang, X.J.2
Hart, M.J.3
-
15
-
-
0032568868
-
Direct stimulation of the guanine nucleotide exchange activity of P115 RhoGEF by Gα13
-
Hart MJ, Jiang XJ, Kozasa T, et al. Direct stimulation of the guanine nucleotide exchange activity of P115 RhoGEF by Gα13. Science 1998; 280:2112-4.
-
(1998)
Science
, vol.280
, pp. 2112-2114
-
-
Hart, M.J.1
Jiang, X.J.2
Kozasa, T.3
-
16
-
-
0032475863
-
G protein signaling events are activated at the leading edge of chemotactic cells
-
Parent CA, Blacklock BJ, Froehlich WM, Murphy DB, Devreotes PN. G protein signaling events are activated at the leading edge of chemotactic cells. Cell 1998; 95:81-91.
-
(1998)
Cell
, vol.95
, pp. 81-91
-
-
Parent, C.A.1
Blacklock, B.J.2
Froehlich, W.M.3
Murphy, D.B.4
Devreotes, P.N.5
-
17
-
-
0034635513
-
Polarization of chemoattractant receptor signaling during neutrophil chemotaxis
-
Servant G, Weiner OD, Herzmark P. et al. Polarization of chemoattractant receptor signaling during neutrophil chemotaxis. Science 2000; 287:1037-40.
-
(2000)
Science
, vol.287
, pp. 1037-1040
-
-
Servant, G.1
Weiner, O.D.2
Herzmark, P.3
-
18
-
-
0034638836
-
Spatial sensing in fibroblasts mediated by 3′ phosphoinositides
-
Haugh JM, Codazzi F, Teruel M, Meyer T. Spatial sensing in fibroblasts mediated by 3′ phosphoinositides. J Cell Biol 2000; 151:1269-80.
-
(2000)
J Cell Biol
, vol.151
, pp. 1269-1280
-
-
Haugh, J.M.1
Codazzi, F.2
Teruel, M.3
Meyer, T.4
-
19
-
-
0034911881
-
Synthesis and function of 3-phosphorylated inositol lipids
-
Vanhaesebroeck B, Leevers SJ, Ahmadi K, et al. Synthesis and function of 3-phosphorylated inositol lipids. Annu Rev Biochem 2001; 70:535-602.
-
(2001)
Annu Rev Biochem
, vol.70
, pp. 535-602
-
-
Vanhaesebroeck, B.1
Leevers, S.J.2
Ahmadi, K.3
-
20
-
-
0032929762
-
Signalling through phosphoinositide 3-kinases: The lipids take centre stage
-
Leevers SJ, Vanhaesebroeck B, Waterfield MD. Signalling through phosphoinositide 3-kinases: the lipids take centre stage. Curr Opin Cell Biol 1999; 11:219-25.
-
(1999)
Curr Opin Cell Biol
, vol.11
, pp. 219-225
-
-
Leevers, S.J.1
Vanhaesebroeck, B.2
Waterfield, M.D.3
-
21
-
-
13144277541
-
Inositol phospholipids: Translocation, translocation, translocation
-
Irvine R. Inositol phospholipids: translocation, translocation, translocation. Curr Biol 1998; 8:R557-9.
-
(1998)
Curr Biol
, vol.8
-
-
Irvine, R.1
-
22
-
-
0033603214
-
Phosphoinositide binding domains: Embracing 3-phosphate
-
Fruman DA, Rameh LE, Cantley LC. Phosphoinositide binding domains: embracing 3-phosphate. Cell 1999; 97:817-20.
-
(1999)
Cell
, vol.97
, pp. 817-820
-
-
Fruman, D.A.1
Rameh, L.E.2
Cantley, L.C.3
-
23
-
-
0030887632
-
The G beta-gamma sensitivity of a PI3K is dependent upon a tightly associated adaptor, p101
-
Stephens LR, Eguinoa A, Erdjument-Bromage H, et al. The G beta-gamma sensitivity of a PI3K is dependent upon a tightly associated adaptor, p101. Cell 1997; 89:105-14.
-
(1997)
Cell
, vol.89
, pp. 105-114
-
-
Stephens, L.R.1
Eguinoa, A.2
Erdjument-Bromage, H.3
-
24
-
-
0031037296
-
Linkage of G protein-coupled receptors to the MAPK signaling pathway through PI 3-kinase gamma
-
Lopez-Ilasaca M, Crespo P, Pellici PG, Gutkind JS, Wetzker R. Linkage of G protein-coupled receptors to the MAPK signaling pathway through PI 3-kinase gamma. Science 1997; 275:394-7.
-
(1997)
Science
, vol.275
, pp. 394-397
-
-
Lopez-Ilasaca, M.1
Crespo, P.2
Pellici, P.G.3
Gutkind, J.S.4
Wetzker, R.5
-
25
-
-
0030936323
-
PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer
-
Li J, Yen C, Liaw D, et al. PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer. Science 1997; 275:1943-7.
-
(1997)
Science
, vol.275
, pp. 1943-1947
-
-
Li, J.1
Yen, C.2
Liaw, D.3
-
26
-
-
0034635452
-
Central role for G protein-coupled phosphoinositide 3-kinase gamma in inflammation
-
Hirsch E, Katanaev VL, Garland C, et al. Central role for G protein-coupled phosphoinositide 3-kinase gamma in inflammation. Science 2000; 287:1049-53.
-
(2000)
Science
, vol.287
, pp. 1049-1053
-
-
Hirsch, E.1
Katanaev, V.L.2
Garland, C.3
-
27
-
-
0034635264
-
Function of PI3Kgamma in thymocyte development, T cell activation, and neutrophil migration
-
Sasaki T, Irie-Sasaki J, Jones RG, et al. Function of PI3Kgamma in thymocyte development, T cell activation, and neutrophil migration. Science 2000; 287:1040-6.
-
(2000)
Science
, vol.287
, pp. 1040-1046
-
-
Sasaki, T.1
Irie-Sasaki, J.2
Jones, R.G.3
-
28
-
-
0037133606
-
Neutrophils lacking phosphoinositide 3-kinase gamma show loss of directionality during N-formyl-Met-Leu-Phe-induced chemotaxis
-
U S A
-
Hannigan M, Zhan L, Li Z, et al. Neutrophils lacking phosphoinositide 3-kinase gamma show loss of directionality during N-formyl-Met-Leu-Phe-induced chemotaxis. Proc Natl Acad Sci U S A 2002; 99:3603-8.
-
(2002)
Proc Natl Acad Sci
, vol.99
, pp. 3603-3608
-
-
Hannigan, M.1
Zhan, L.2
Li, Z.3
-
29
-
-
0035858886
-
Role of phosphatidylinositol 3′ kinase and a downstream pleckstrin homology domain-containing protein in controlling chemotaxis in dictyostelium
-
Funamoto S, Milan K, Meili R, Firtel RA. Role of phosphatidylinositol 3′ kinase and a downstream pleckstrin homology domain-containing protein in controlling chemotaxis in dictyostelium. J Cell Biol 2001; 153:795-810.
-
(2001)
J Cell Biol
, vol.153
, pp. 795-810
-
-
Funamoto, S.1
Milan, K.2
Meili, R.3
Firtel, R.A.4
-
30
-
-
0033838716
-
Regulation of cell function by Rho family GTPases
-
Bokoch GM. Regulation of cell function by Rho family GTPases. Immunol Res 2000; 21:139-48.
-
(2000)
Immunol Res
, vol.21
, pp. 139-148
-
-
Bokoch, G.M.1
-
31
-
-
0032559362
-
Rho GTPases and the actin cytoskeleton
-
Hall A. Rho GTPases and the actin cytoskeleton. Science 1998; 279:509-14.
-
(1998)
Science
, vol.279
, pp. 509-514
-
-
Hall, A.1
-
32
-
-
0037069690
-
Rho GTPases in cell biology
-
Etienne-Manneville S, Hall A. Rho GTPases in cell biology. Nature 2002; 420:629-35.
-
(2002)
Nature
, vol.420
, pp. 629-635
-
-
Etienne-Manneville, S.1
Hall, A.2
-
33
-
-
0141533034
-
Roles of Rho-family GTPases in cell polarisation and directional migration
-
Fukata M, Nakagawa M, Kaibuchi K. Roles of Rho-family GTPases in cell polarisation and directional migration. Curr Opin Cell Biol 2003; 15:590-7.
-
(2003)
Curr Opin Cell Biol
, vol.15
, pp. 590-597
-
-
Fukata, M.1
Nakagawa, M.2
Kaibuchi, K.3
-
34
-
-
0033007293
-
Cdc42: An essential Rho-type GTPase controlling eukaryotic cell polarity
-
Johnson DI. Cdc42: An essential Rho-type GTPase controlling eukaryotic cell polarity. Microbiol Mol Biol Rev 1999; 63:54-105.
-
(1999)
Microbiol Mol Biol Rev
, vol.63
, pp. 54-105
-
-
Johnson, D.I.1
-
35
-
-
1542374119
-
Parsing the polarity code
-
Macara IG. Parsing the polarity code. Nat Rev Mol Cell Biol 2004; 5:220-31.
-
(2004)
Nat Rev Mol Cell Biol
, vol.5
, pp. 220-231
-
-
Macara, I.G.1
-
37
-
-
0031610579
-
PAK kinases are directly coupled to the PIX family of nucleotide exchange factors
-
Manser E, Loo TH, Koh CG, et al. PAK kinases are directly coupled to the PIX family of nucleotide exchange factors. Molecular Cell 1998; 1:183-92.
-
(1998)
Molecular Cell
, vol.1
, pp. 183-192
-
-
Manser, E.1
Loo, T.H.2
Koh, C.G.3
-
38
-
-
0033525229
-
AlphaPix stimulates p21-activated kinase activity through exchange factor-dependent and -independent mechanisms
-
Daniels RH, Zenke FT, Bokoch GM. alphaPix stimulates p21-activated kinase activity through exchange factor-dependent and -independent mechanisms. J Biol Chem 1999; 274:6047-50.
-
(1999)
J Biol Chem
, vol.274
, pp. 6047-6050
-
-
Daniels, R.H.1
Zenke, F.T.2
Bokoch, G.M.3
-
39
-
-
4644343782
-
Novel regulatory mechanisms for the Dbl family guanine nucleotide exchange factor Cool-2/alpha-Pix
-
Feng Q, Baird D, Cerione RA. Novel regulatory mechanisms for the Dbl family guanine nucleotide exchange factor Cool-2/alpha-Pix. Embo J 2004; 23:3492-504.
-
(2004)
Embo J
, vol.23
, pp. 3492-3504
-
-
Feng, Q.1
Baird, D.2
Cerione, R.A.3
-
40
-
-
0033279824
-
Cell polarity in yeast
-
Chant J. Cell polarity in yeast. Annu Rev Cell Dev Biol 1999; 15:365-91.
-
(1999)
Annu Rev Cell Dev Biol
, vol.15
, pp. 365-391
-
-
Chant, J.1
-
41
-
-
0033593974
-
A Cdc24p-Far1p-Gbetagamma protein complex required for yeast orientation during mating
-
Nern A, Arkowitz RA. A Cdc24p-Far1p-Gbetagamma protein complex required for yeast orientation during mating. J Cell Biol 1999; 144:1187-202.
-
(1999)
J Cell Biol
, vol.144
, pp. 1187-1202
-
-
Nern, A.1
Arkowitz, R.A.2
-
42
-
-
0032495489
-
A GTP-exchange factor required for cell orientation
-
Nern A, Arkowitz RA. A GTP-exchange factor required for cell orientation. Nature 1998; 391:195-8.
-
(1998)
Nature
, vol.391
, pp. 195-198
-
-
Nern, A.1
Arkowitz, R.A.2
-
43
-
-
0036773899
-
Temporal and spatial regulation of chemotaxis
-
Iijima M, Huang YE, Devreotes P. Temporal and spatial regulation of chemotaxis. Dev Cell 2002; 3:469-78.
-
(2002)
Dev Cell
, vol.3
, pp. 469-478
-
-
Iijima, M.1
Huang, Y.E.2
Devreotes, P.3
-
44
-
-
0036532115
-
Regulation of cell polarity during eukaryotic chemotaxis: The chemotactic compass
-
Weiner OD. Regulation of cell polarity during eukaryotic chemotaxis: the chemotactic compass. Curr Opin Cell Biol 2002; 14:196-202.
-
(2002)
Curr Opin Cell Biol
, vol.14
, pp. 196-202
-
-
Weiner, O.D.1
-
45
-
-
0037205265
-
Spatial and temporal regulation of 3-phosphoinositides by PI 3-kinase and PTEN mediates chemotaxis
-
Funamoto S, Meili R, Lee S, Parry L, Firtel RA. Spatial and temporal regulation of 3-phosphoinositides by PI 3-kinase and PTEN mediates chemotaxis. Cell 2002; 109:611-23.
-
(2002)
Cell
, vol.109
, pp. 611-623
-
-
Funamoto, S.1
Meili, R.2
Lee, S.3
Parry, L.4
Firtel, R.A.5
-
46
-
-
0037205230
-
Tumor suppressor PTEN mediates sensing of chemoattractant gradients
-
Iijima M, Devreotes P. Tumor suppressor PTEN mediates sensing of chemoattractant gradients. Cell 2002; 109:599-610.
-
(2002)
Cell
, vol.109
, pp. 599-610
-
-
Iijima, M.1
Devreotes, P.2
-
47
-
-
0034681264
-
The multiple roles of PTEN in tumor suppression
-
Di Cristofano A, Pandolfi PP. The multiple roles of PTEN in tumor suppression. Cell 2000; 100:387-90.
-
(2000)
Cell
, vol.100
, pp. 387-390
-
-
Di Cristofano, A.1
Pandolfi, P.P.2
-
48
-
-
0036181869
-
PTEN: The down side of PI 3-kinase signalling
-
Leslie NR, Downes CP. PTEN: The down side of PI 3-kinase signalling. Cell Signal 2002; 14:285-95.
-
(2002)
Cell Signal
, vol.14
, pp. 285-295
-
-
Leslie, N.R.1
Downes, C.P.2
-
49
-
-
0036899518
-
PTEN and myotubularin phosphatases: From 3-phosphoinositide dephosphorylation to disease
-
Wishart MJ, Dixon JE. PTEN and myotubularin phosphatases: from 3-phosphoinositide dephosphorylation to disease. Trends Cell Biol 2002; 12:579-85.
-
(2002)
Trends Cell Biol
, vol.12
, pp. 579-585
-
-
Wishart, M.J.1
Dixon, J.E.2
-
50
-
-
0142011466
-
PTEN: From pathology to biology
-
Sulis ME, Parsons R. PTEN: from pathology to biology. Trends Cell Biol 2003; 13:478-83.
-
(2003)
Trends Cell Biol
, vol.13
, pp. 478-483
-
-
Sulis, M.E.1
Parsons, R.2
-
51
-
-
0033551070
-
New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway
-
USA
-
Cantley LC, Neel BG. New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway. Proc Natl Acad Sci USA 1999; 96:4240-5.
-
(1999)
Proc Natl Acad Sci
, vol.96
, pp. 4240-4245
-
-
Cantley, L.C.1
Neel, B.G.2
-
52
-
-
0042316755
-
PTEN: One gene, many syndromes
-
Eng C. PTEN: one gene, many syndromes. Hum Mutat 2003; 22:183-98.
-
(2003)
Hum Mutat
, vol.22
, pp. 183-198
-
-
Eng, C.1
-
53
-
-
0034635221
-
Roles of PLC-beta2 and -beta3 and PI3Kgamma in chemoattractant-mediated signal transduction
-
Li Z, Jiang H, Xie W, et al. Roles of PLC-beta2 and -beta3 and PI3Kgamma in chemoattractant-mediated signal transduction. Science 2000; 287:1046-9.
-
(2000)
Science
, vol.287
, pp. 1046-1049
-
-
Li, Z.1
Jiang, H.2
Xie, W.3
-
54
-
-
0142084736
-
Hematopoietic cell regulation by Rac1 and Rac2 guanosine triphosphatases
-
Gu Y, Filippi MD, Cancelas JA, et al. Hematopoietic cell regulation by Rac1 and Rac2 guanosine triphosphatases. Science 2003; 302:445-9.
-
(2003)
Science
, vol.302
, pp. 445-449
-
-
Gu, Y.1
Filippi, M.D.2
Cancelas, J.A.3
-
55
-
-
0037415640
-
Rac and Cdc42 play distinct roles in regulating PI(3,4,5)P3 and polarity during neutrophil chemotaxis
-
Srinivasan S, Wang F, Glavas S, et al. Rac and Cdc42 play distinct roles in regulating PI(3,4,5)P3 and polarity during neutrophil chemotaxis. J Cell Biol 2003; 160:375-85.
-
(2003)
J Cell Biol
, vol.160
, pp. 375-385
-
-
Srinivasan, S.1
Wang, F.2
Glavas, S.3
-
56
-
-
0037155727
-
P-Rex1, a PtdIns(3,4, 5)P3- and Gbetagamma-regulated guanine-nucleotide exchange factor for Rac
-
Welch HC, Coadwell WJ, Ellson CD, et al. P-Rex1, a PtdIns(3,4, 5)P3- and Gbetagamma-regulated guanine-nucleotide exchange factor for Rac. Cell 2002; 108:809-21.
-
(2002)
Cell
, vol.108
, pp. 809-821
-
-
Welch, H.C.1
Coadwell, W.J.2
Ellson, C.D.3
|