Rac and Cdc42 play distinct roles in regulating PI(3,4,5)P3 and polarity during neutrophil chemotaxis

Journal of Cell Biology

Volumn 160, Issue 3, 2003, Pages 375-385

  Srinivasan, Supriya ^a   Wang, Fei ^a   Glavas, Suzana ^a   Ott, Alexander ^a   Hofmann, Fred ^b   Aktories, Klaus ^b   Kalman, Daniel ^c   Bourne, Henry R ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF FREIBURG   (Germany)

^c EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Actin; Chemoattractant; PI 3 kinase; Positive feedback; Pseudopod

Indexed keywords

ACTIN; FLUORESCENT DYE; GREEN FLUORESCENT PROTEIN; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE; PROTEIN CDC42; PROTEIN INHIBITOR; PROTEIN P21; RAC PROTEIN;

ACTIN POLYMERIZATION; ARTICLE; BINDING SITE; CELL MEMBRANE; CELL MEMBRANE TRANSPORT; CELL POLARITY; CELL STRAIN HL 60; CONTROLLED STUDY; ENZYME ACTIVATION; GENE ACTIVATION; GENE CONTROL; HUMAN; HUMAN CELL; LIPID MEMBRANE; NEUTROPHIL CHEMOTAXIS; POSITIVE FEEDBACK; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN STABILITY;

ACTINS; ANIMALS; BACTERIAL TOXINS; CDC42 GTP-BINDING PROTEIN; CELL MEMBRANE; CELL POLARITY; CHEMOTAXIS, LEUKOCYTE; COS CELLS; FEEDBACK, BIOCHEMICAL; GREEN FLUORESCENT PROTEINS; HL-60 CELLS; HUMANS; INOSITOL PHOSPHATES; LUMINESCENT PROTEINS; N-FORMYLMETHIONINE LEUCYL-PHENYLALANINE; NEUTROPHILS; PROTEIN TRANSPORT; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; PSEUDOPODIA; RAC GTP-BINDING PROTEINS; RECOMBINANT FUSION PROTEINS;

PSEUDOPODA;

EID: 0037415640     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.200208179     Document Type: Article

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