Presenilin-1-deficient neurons are nitric oxide-dependently killed by hydrogen peroxide in vitro

Neuroscience

Volumn 125, Issue 3, 2004, Pages 563-568

  Nakajima, M ^a   Shirasawa, T ^a  

^a TOKYO METROPOLITAN INSTITUTE OF GERONTOLOGY   (Japan)

Author keywords

A ; AD; Alzheimer's disease; Amyloid protein; Amyloid precursor protein; APP; Endothelial nitric oxide synthase; eNOS; FAD; Familial Alzheimer's disease; Hemoglobin; iNOS; JNK; L NAME; NADPH diaphorase; Nitric oxide synthase; p38

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; CALCINEURIN; CALPAIN; CALPASTATIN; HEMOGLOBIN; HYDROGEN PEROXIDE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; N [[5 [(2 AMINO 3 MERCAPTOPROPYL)AMINO][1,1' BIPHENYL] 2 YL]CARBONYL]METHIONINE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PRESENILIN 1; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE DEHYDROGENASE; STRESS ACTIVATED PROTEIN KINASE;

ANIMAL CELL; ARTICLE; CELL MUTANT; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVATION; GENE EXPRESSION; MOUSE; NERVE CELL CULTURE; NERVE CELL NECROSIS; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; STAINING;

ALZHEIMER DISEASE; ANIMALS; CALCIUM-BINDING PROTEINS; CELLS, CULTURED; ENZYME INHIBITORS; FREE RADICAL SCAVENGERS; GENETIC PREDISPOSITION TO DISEASE; HEMOGLOBINS; HYDROGEN PEROXIDE; MAP KINASE SIGNALING SYSTEM; MEMBRANE PROTEINS; MICE; MICE, KNOCKOUT; NADPH DEHYDROGENASE; NERVE DEGENERATION; NEURONS; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; OXIDANTS; OXIDATIVE STRESS; PRESENILIN-1;

EID: 1942489069     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2004.01.016     Document Type: Article

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