-
1
-
-
0344622606
-
The serial cultivation of human diploid cell strains
-
Hayflick L, Moorhead PS. The serial cultivation of human diploid cell strains. Exp Cell Res 1961, 25, 585-621.
-
(1961)
Exp Cell Res
, vol.25
, pp. 585-621
-
-
Hayflick, L.1
Moorhead, P.S.2
-
2
-
-
0028322713
-
SV40-induced immortalization of human cells
-
Bryan TM, Reddel RR. SV40-induced immortalization of human cells. Crit Rev Oncogenesis 1994, 5, 331-357.
-
(1994)
Crit Rev Oncogenesis
, vol.5
, pp. 331-357
-
-
Bryan, T.M.1
Reddel, R.R.2
-
3
-
-
0027769876
-
A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4
-
Serrano M, Hannon GJ, Beach D. A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4. Nature 1993, 366, 704-707.
-
(1993)
Nature
, vol.366
, pp. 704-707
-
-
Serrano, M.1
Hannon, G.J.2
Beach, D.3
-
4
-
-
0028034775
-
Transcriptional repression of the D-type cyclin-dependent kinase inhibitor p16 by the retinoblastoma susceptibility gene product pRb
-
Li Y, Nichols MA, Shay JW, Xiong Y. Transcriptional repression of the D-type cyclin-dependent kinase inhibitor p16 by the retinoblastoma susceptibility gene product pRb. Cancer Res 1994, 54, 6078-6082.
-
(1994)
Cancer Res
, vol.54
, pp. 6078-6082
-
-
Li, Y.1
Nichols, M.A.2
Shay, J.W.3
Xiong, Y.4
-
7
-
-
0028988245
-
INK4 and retinoblastoma tumour-suppressor genes occur in distinct sub-sets of human cancer cell lines
-
INK4 and retinoblastoma tumour-suppressor genes occur in distinct sub-sets of human cancer cell lines. Int J Cancer 1995, 61, 115-120.
-
(1995)
Int J Cancer
, vol.61
, pp. 115-120
-
-
Aagaard, L.1
Lukas, J.2
Bartkova, J.3
Kjerulff, A.-A.4
Strauss, M.5
Bartek, J.6
-
11
-
-
0028911406
-
Increased p16 levels correlate with pRB alterations in human urothelial cells
-
Yeager T, Stadler W, Belair C, Puthenveettil J, Olopade O. Reznikoff C. Increased p16 levels correlate with pRB alterations in human urothelial cells. Cancer Res 1995, 55, 493-497.
-
(1995)
Cancer Res
, vol.55
, pp. 493-497
-
-
Yeager, T.1
Stadler, W.2
Belair, C.3
Puthenveettil, J.4
Olopade, O.5
Reznikoff, C.6
-
12
-
-
0028981380
-
INK4 expression and telomere length during spontaneous immortalization of Li-Fraumem syndrome fibroblasts
-
INK4 expression and telomere length during spontaneous immortalization of Li-Fraumem syndrome fibroblasts. Mol Cell Biol 1995, 15, 4745-4753.
-
(1995)
Mol Cell Biol
, vol.15
, pp. 4745-4753
-
-
Rogan, E.M.1
Bryan, T.M.2
Hukku, B.3
-
13
-
-
0029807327
-
INK4 expression
-
INK4 expression. Oncogene 1996, 13, 1259-1268.
-
(1996)
Oncogene
, vol.13
, pp. 1259-1268
-
-
Noble, J.R.1
Rogan, E.M.2
Neumann, A.A.3
Maclean, K.4
Bryan, T.M.5
Reddel, R.R.6
-
14
-
-
0002889389
-
SV40-induced transformation of human diploid cells: Crisis and recovery
-
Girardi AJ, Jensen FC, Koprowski H. SV40-induced transformation of human diploid cells: crisis and recovery. J Cell Comp Physiol 1965, 65, 69-84.
-
(1965)
J Cell Comp Physiol
, vol.65
, pp. 69-84
-
-
Girardi, A.J.1
Jensen, F.C.2
Koprowski, H.3
-
15
-
-
0027496456
-
The frequency of immortalization of human fibroblasts and mammary epithelial cells transfected with SV40 large T-antigen
-
Shay JW, Van Der Haegen BA, Ying Y, Wright WE. The frequency of immortalization of human fibroblasts and mammary epithelial cells transfected with SV40 large T-antigen. Exp Cell Res 1993, 209, 45-52.
-
(1993)
Exp Cell Res
, vol.209
, pp. 45-52
-
-
Shay, J.W.1
Van Der Haegen, B.A.2
Ying, Y.3
Wright, W.E.4
-
16
-
-
0025731583
-
Structure and function of telomeres
-
Blackburn EH. Structure and function of telomeres. Nature 1991, 350, 569-573.
-
(1991)
Nature
, vol.350
, pp. 569-573
-
-
Blackburn, E.H.1
-
17
-
-
0025279931
-
Telomeres shorten during ageing of human fibroblasts
-
Harley CB, Futcher AB, Greider CW. Telomeres shorten during ageing of human fibroblasts. Nature 1990, 345, 458-460.
-
(1990)
Nature
, vol.345
, pp. 458-460
-
-
Harley, C.B.1
Futcher, A.B.2
Greider, C.W.3
-
18
-
-
0025143252
-
Telomere reduction in human colorectal carcinoma and with ageing
-
Hastie ND, Dempster M, Dunlop MG, Thompson AM, Green DK, Allshire RC. Telomere reduction in human colorectal carcinoma and with ageing. Nature 1990, 346, 866-868.
-
(1990)
Nature
, vol.346
, pp. 866-868
-
-
Hastie, N.D.1
Dempster, M.2
Dunlop, M.G.3
Thompson, A.M.4
Green, D.K.5
Allshire, R.C.6
-
19
-
-
0026043444
-
In vivo loss of telomeric repeats with age in humans
-
Lindsey J, McGill NI, Lindsey LA, Green DK, Cooke HJ. In vivo loss of telomeric repeats with age in humans. Mutat Res 1991, 256, 45-48.
-
(1991)
Mutat Res
, vol.256
, pp. 45-48
-
-
Lindsey, J.1
McGill, N.I.2
Lindsey, L.A.3
Green, D.K.4
Cooke, H.J.5
-
20
-
-
0027486732
-
Loss of telomeric DNA during aging of normal and trisomy 21 human lymphocytes
-
Vaziri H, Schächter F, Uchida I, et al. Loss of telomeric DNA during aging of normal and trisomy 21 human lymphocytes. Am J Hum Genet 1993, 52, 661-667.
-
(1993)
Am J Hum Genet
, vol.52
, pp. 661-667
-
-
Vaziri, H.1
Schächter, F.2
Uchida, I.3
-
21
-
-
0001029496
-
Principle of marginotomy in template synthesis of polynucleotides
-
Olovnikov AM. Principle of marginotomy in template synthesis of polynucleotides. Doklady Biochetn 1971, 201, 394-397.
-
(1971)
Doklady Biochetn
, vol.201
, pp. 394-397
-
-
Olovnikov, A.M.1
-
22
-
-
0029939848
-
Heterogeneity in telomere length of human chromosomes
-
Lansdorp PM, Verwoerd NP, Van de Rijke FM, et al. Heterogeneity in telomere length of human chromosomes. Hum Mol Genet 1996, 5, 685-691.
-
(1996)
Hum Mol Genet
, vol.5
, pp. 685-691
-
-
Lansdorp, P.M.1
Verwoerd, N.P.2
Van De Rijke, F.M.3
-
23
-
-
0030006735
-
In situ analysis of changes in telomere size during replicative aging and cell transformation
-
Henderson S, Allsopp R, Spector D, Wang S-S, Harley C. In situ analysis of changes in telomere size during replicative aging and cell transformation. J Cell Biol 1996, 134, 1-12.
-
(1996)
J Cell Biol
, vol.134
, pp. 1-12
-
-
Henderson, S.1
Allsopp, R.2
Spector, D.3
Wang, S.-S.4
Harley, C.5
-
24
-
-
0026460896
-
Telomere length predicts replicative capacity of human fibroblasts
-
Allsopp RC, Vaziri H, Patterson C, et al. Telomere length predicts replicative capacity of human fibroblasts. Proc Natl Acad Sci USA 1992, 89, 10114-10118.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 10114-10118
-
-
Allsopp, R.C.1
Vaziri, H.2
Patterson, C.3
-
25
-
-
0029145379
-
Evidence for a critical telomere length in senescent human fibroblasts
-
Allsopp RC, Harley CB. Evidence for a critical telomere length in senescent human fibroblasts. Exp Cell Res 1995, 219, 130 136.
-
(1995)
Exp Cell Res
, vol.219
, pp. 130-136
-
-
Allsopp, R.C.1
Harley, C.B.2
-
26
-
-
0023034140
-
Variability at the telomeres of the human X/Y pseudoautosomal region
-
Cooke HJ, Smith BA. Variability at the telomeres of the human X/Y pseudoautosomal region. Cold Spring Harbor Symp Quant Biol 1986, 51, 213-219.
-
(1986)
Cold Spring Harbor Symp Quant Biol
, vol.51
, pp. 213-219
-
-
Cooke, H.J.1
Smith, B.A.2
-
27
-
-
0023941599
-
Telomeric repeat from T. thermophila cross hybridizes with human telomeres
-
Allshire RC, Gosden JR, Cross SH, et al. Telomeric repeat from T. thermophila cross hybridizes with human telomeres. Nature 1988, 332, 656-659.
-
(1988)
Nature
, vol.332
, pp. 656-659
-
-
Allshire, R.C.1
Gosden, J.R.2
Cross, S.H.3
-
28
-
-
0025115349
-
Structure and variability of human chromosome ends
-
De Lange T, Shiue L, Myers RM, et al. Structure and variability of human chromosome ends. Mol Cell Biol 1990, 10, 518-527.
-
(1990)
Mol Cell Biol
, vol.10
, pp. 518-527
-
-
De Lange, T.1
Shiue, L.2
Myers, R.M.3
-
29
-
-
0022402513
-
Identification of a specific telomere terminal transferase activity in Tetrahymena extracts
-
Greider CW, Blackburn EH. Identification of a specific telomere terminal transferase activity in Tetrahymena extracts. Cell 1985, 43, 405-413.
-
(1985)
Cell
, vol.43
, pp. 405-413
-
-
Greider, C.W.1
Blackburn, E.H.2
-
30
-
-
0025787643
-
Telomere loss: Mitotic clock or genetic time bomb?
-
Harley CB. Telomere loss: mitotic clock or genetic time bomb? Mutat Res 1991, 256, 271-282.
-
(1991)
Mutat Res
, vol.256
, pp. 271-282
-
-
Harley, C.B.1
-
31
-
-
0026628668
-
The telomere hypothesis of cellular aging
-
Harley CB, Vaziri H, Counter CM, Allsopp RC. The telomere hypothesis of cellular aging. Exp Gerontol 1992, 27, 375-382.
-
(1992)
Exp Gerontol
, vol.27
, pp. 375-382
-
-
Harley, C.B.1
Vaziri, H.2
Counter, C.M.3
Allsopp, R.C.4
-
32
-
-
0024325562
-
The human telomere terminal transferase enzyme is a ribonucleoprotein that synthesizes TTAGGG repeats
-
Morin GB. The human telomere terminal transferase enzyme is a ribonucleoprotein that synthesizes TTAGGG repeats. Cell 1989, 59, 521-529.
-
(1989)
Cell
, vol.59
, pp. 521-529
-
-
Morin, G.B.1
-
33
-
-
0028201293
-
Activation of telomerase in a human tumor
-
De Lange T. Activation of telomerase in a human tumor. Proc Natl Acad Sci USA 1994, 91, 2882-2885.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 2882-2885
-
-
De Lange, T.1
-
34
-
-
0026682717
-
Telomere positional effects and the regulation of cellular senescence
-
Wright WE, Shay JW. Telomere positional effects and the regulation of cellular senescence. Trends Genet 1992, 8, 193-197.
-
(1992)
Trends Genet
, vol.8
, pp. 193-197
-
-
Wright, W.E.1
Shay, J.W.2
-
35
-
-
0026523228
-
Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity
-
Counter CM, Avilion AA, LeFeuvre CE, et al. Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity. EMBO J 1992, 11, 1921-1929.
-
(1992)
EMBO J
, vol.11
, pp. 1921-1929
-
-
Counter, C.M.1
Avilion, A.A.2
LeFeuvre, C.E.3
-
36
-
-
0028198679
-
Stabilization of short telomeres and telomerase activity accompany immortalization of Epstein-Barr virus-transformed human B lymphocytes
-
Counter CM, Botelho FM, Wang P, Harley CB, Bacchetti S. Stabilization of short telomeres and telomerase activity accompany immortalization of Epstein-Barr virus-transformed human B lymphocytes. J Virol 1994, 68, 3410-3414.
-
(1994)
J Virol
, vol.68
, pp. 3410-3414
-
-
Counter, C.M.1
Botelho, F.M.2
Wang, P.3
Harley, C.B.4
Bacchetti, S.5
-
37
-
-
0028140264
-
Restoration of telomeres in human papillomavirus-immortalized human anogemtal epithelial cells
-
Klnigelhutz AJ, Barber SA, Smith PP, Dyer K, McDougall JK. Restoration of telomeres in human papillomavirus-immortalized human anogemtal epithelial cells. Mol Cell Biol 1994, 14, 961-969.
-
(1994)
Mol Cell Biol
, vol.14
, pp. 961-969
-
-
Klnigelhutz, A.J.1
Barber, S.A.2
Smith, P.P.3
Dyer, K.4
McDougall, J.K.5
-
38
-
-
0028564951
-
Specific association of human telomerase activity with immortal cells and cancer
-
Kim NW, Piatyszek MA, Prowse KR, et al. Specific association of human telomerase activity with immortal cells and cancer. Science 1994, 266, 2011-2015.
-
(1994)
Science
, vol.266
, pp. 2011-2015
-
-
Kim, N.W.1
Piatyszek, M.A.2
Prowse, K.R.3
-
39
-
-
0028936194
-
Spontaneous in vitro immortalization of breast epithelial cells from a patient with Li-Fraumeni syndrome
-
Shay JW, Tomlinson G, Piatyszek MA, Gollahon LS. Spontaneous in vitro immortalization of breast epithelial cells from a patient with Li-Fraumeni syndrome. Mol Cell Biol 1995, 15, 425-432.
-
(1995)
Mol Cell Biol
, vol.15
, pp. 425-432
-
-
Shay, J.W.1
Tomlinson, G.2
Piatyszek, M.A.3
Gollahon, L.S.4
-
41
-
-
0030047089
-
p53 levels in human mammary epithelial cells expressing wild-type and mutant human papillomavirus type 16 (HPV-16) E6 proteins: Relationship to reactivation of telomerase and immortalization
-
Holt SE, Gollahon LS, Willingham T, Barbosa MS, Shay JW. p53 levels in human mammary epithelial cells expressing wild-type and mutant human papillomavirus type 16 (HPV-16) E6 proteins: relationship to reactivation of telomerase and immortalization, Int J Oncol 1996, 8, 262-270.
-
(1996)
Int J Oncol
, vol.8
, pp. 262-270
-
-
Holt, S.E.1
Gollahon, L.S.2
Willingham, T.3
Barbosa, M.S.4
Shay, J.W.5
-
42
-
-
0029162563
-
Telomere elongation in immortal human cells without detectable telomerase activity
-
Bryan TM, Englezou A, Gupta J, Bacchetti S, Reddel RR. Telomere elongation in immortal human cells without detectable telomerase activity. EMBO J 1995, 14, 4240-4248.
-
(1995)
EMBO J
, vol.14
, pp. 4240-4248
-
-
Bryan, T.M.1
Englezou, A.2
Gupta, J.3
Bacchetti, S.4
Reddel, R.R.5
-
43
-
-
0030067487
-
Human telomerase RNA and telomerase activity in immortal cell lines and tumor tissues
-
Avilion AA, Piatyszek MA, Gupta J, Shay JW, Bacchetti S, Greider CW. Human telomerase RNA and telomerase activity in immortal cell lines and tumor tissues. Cancer Res 1996, 56, 645-650.
-
(1996)
Cancer Res
, vol.56
, pp. 645-650
-
-
Avilion, A.A.1
Piatyszek, M.A.2
Gupta, J.3
Shay, J.W.4
Bacchetti, S.5
Greider, C.W.6
-
44
-
-
0027956728
-
Telomerase activity in vivo in human malignant hematopoietic cells
-
Nilsson P, Mehle C, Remes K, Roos G. Telomerase activity in vivo in human malignant hematopoietic cells. Oncogene 1994, 9, 3043-3048.
-
(1994)
Oncogene
, vol.9
, pp. 3043-3048
-
-
Nilsson, P.1
Mehle, C.2
Remes, K.3
Roos, G.4
-
45
-
-
0028007237
-
Telomere dynamics in an immortal human cell line
-
Murnane JP, Sabatier L, Marder BA, Morgan WF. Telomere dynamics in an immortal human cell line. EMBO J 1994, 13, 4953-4962.
-
(1994)
EMBO J
, vol.13
, pp. 4953-4962
-
-
Murnane, J.P.1
Sabatier, L.2
Marder, B.A.3
Morgan, W.F.4
-
46
-
-
0029901910
-
Telomerase activity in the regenerative basal layer of the epidermis in human skin and in immortal and carcinoma-derived skin keratinocytes
-
Härle-Bachor C, Boukamp P. Telomerase activity in the regenerative basal layer of the epidermis in human skin and in immortal and carcinoma-derived skin keratinocytes. Proc Natl Acad Sci USA 1996, 93, 6476-6481.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 6476-6481
-
-
Härle-Bachor, C.1
Boukamp, P.2
-
47
-
-
0030008177
-
Telomerase activation by the E6 gene product of human papillomavirus type 16
-
Klingelhutz AJ, Foster SA, McDougall JK. Telomerase activation by the E6 gene product of human papillomavirus type 16. Nature 1996, 380, 79-82.
-
(1996)
Nature
, vol.380
, pp. 79-82
-
-
Klingelhutz, A.J.1
Foster, S.A.2
McDougall, J.K.3
-
48
-
-
0028938262
-
Telomerase activity in normal leukocytes and in hematologic malignancies
-
Counter CM, Gupta J, Harley CB, Leber B, Bacchetti S. Telomerase activity in normal leukocytes and in hematologic malignancies. Blood 1995, 85, 2315-2320.
-
(1995)
Blood
, vol.85
, pp. 2315-2320
-
-
Counter, C.M.1
Gupta, J.2
Harley, C.B.3
Leber, B.4
Bacchetti, S.5
-
49
-
-
0029066169
-
Telomerase activity in normal and malignant hematopoietic cells
-
Broccoli D, Young JW, De Lange T. Telomerase activity in normal and malignant hematopoietic cells. Proc Natl Acad Sci USA 1995, 92, 9082-9086.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 9082-9086
-
-
Broccoli, D.1
Young, J.W.2
De Lange, T.3
-
50
-
-
0028077099
-
Evidence for a mitotic clock in human hematopoietic stem cells: Loss of telomeric DNA with age
-
Vaziri H, Dragowska W, Allsopp RC, Thomas TE, Harley CB, Lansdorp PM. Evidence for a mitotic clock in human hematopoietic stem cells: loss of telomeric DNA with age. Proc Natl Acad Sci USA 1994, 91, 9857-9860.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 9857-9860
-
-
Vaziri, H.1
Dragowska, W.2
Allsopp, R.C.3
Thomas, T.E.4
Harley, C.B.5
Lansdorp, P.M.6
-
51
-
-
0011208723
-
Genetic analysis of indefinite division in human cells: Identification of four complementation groups
-
Pereira-Smith OM, Smith JR. Genetic analysis of indefinite division in human cells: identification of four complementation groups. Proc Natl Acad Sci USA 1988, 85, 6042-6046.
-
(1988)
Proc Natl Acad Sci USA
, vol.85
, pp. 6042-6046
-
-
Pereira-Smith, O.M.1
Smith, J.R.2
-
52
-
-
0024973811
-
A mutant with a defect in telomere elongation leads to senescence in yeast
-
Lundblad V, Szostak JW. A mutant with a defect in telomere elongation leads to senescence in yeast. Cell 1989, 57, 633-643.
-
(1989)
Cell
, vol.57
, pp. 633-643
-
-
Lundblad, V.1
Szostak, J.W.2
-
54
-
-
0024959479
-
Recombination occurs during telomere formation in yeast
-
Pluta AF, Zakian VA. Recombination occurs during telomere formation in yeast. Nature 1989, 337, 429-433.
-
(1989)
Nature
, vol.337
, pp. 429-433
-
-
Pluta, A.F.1
Zakian, V.A.2
-
55
-
-
0025351383
-
Telomere-telomere recombination provides an express pathway for telomere acquisition
-
Wang S-S, Zakian VA. Telomere-telomere recombination provides an express pathway for telomere acquisition, Nature 1990, 345, 456-458.
-
(1990)
Nature
, vol.345
, pp. 456-458
-
-
Wang, S.-S.1
Zakian, V.A.2
-
56
-
-
0029746495
-
Cap-prevented recombination between terminal telomeric repeat arrays (telomere CPR) maintains telomeres in Kluyveromyces lactis lacking telomerase
-
McEachern MJ, Blackburn EH. Cap-prevented recombination between terminal telomeric repeat arrays (telomere CPR) maintains telomeres in Kluyveromyces lactis lacking telomerase. Genes Dev 1996, 10, 1822-1834.
-
(1996)
Genes Dev
, vol.10
, pp. 1822-1834
-
-
McEachern, M.J.1
Blackburn, E.H.2
-
57
-
-
0029114679
-
Telomeres and telomerase in human cancer
-
Bacchetti S, Counter CM. Telomeres and telomerase in human cancer (Review). Int J Oncology 1995, 7, 423-432.
-
(1995)
Int J Oncology
, vol.7
, pp. 423-432
-
-
Bacchetti, S.1
Counter, C.M.2
-
58
-
-
0029890015
-
Telomerase activity in human renal cell carcinoma
-
Mehle C, Piatyszek MA, Ljungberg B, Shay JW, Roos G. Telomerase activity in human renal cell carcinoma. Oncogene 1996, 13, 161-166.
-
(1996)
Oncogene
, vol.13
, pp. 161-166
-
-
Mehle, C.1
Piatyszek, M.A.2
Ljungberg, B.3
Shay, J.W.4
Roos, G.5
-
59
-
-
0025350129
-
Influence of cellular sequences on instability of plasmid integration sites in human cells
-
Murnane JP. Influence of cellular sequences on instability of plasmid integration sites in human cells. Somat Cell Mol Genet 1990, 16, 195-209.
-
(1990)
Somat Cell Mol Genet
, vol.16
, pp. 195-209
-
-
Murnane, J.P.1
-
60
-
-
0027459104
-
Acquisition of telomere repeat sequences by transfected DNA integrated at the site of a chromosome break
-
Murnane JP, Yu L-C. Acquisition of telomere repeat sequences by transfected DNA integrated at the site of a chromosome break. Mol Cell Biol 1993, 13, 977-983.
-
(1993)
Mol Cell Biol
, vol.13
, pp. 977-983
-
-
Murnane, J.P.1
Yu, L.-C.2
|