메뉴 건너뛰기




Volumn 23, Issue 5, 2003, Pages 1710-1718

Overexpression of copper/zinc superoxide dismutase in transgenic mice protects against neuronal cell death after transient focal ischemia by blocking activation of the bad cell death signaling pathway

Author keywords

14 3 3; Apoptosis; Bad; Bcl xL; Cerebral ischemia; Superoxide

Indexed keywords

COPPER; CYCLIC AMP DEPENDENT PROTEIN KINASE; DNA FRAGMENT; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; PROTEIN BAD; PROTEIN BCL XL; SUPEROXIDE DISMUTASE; ZINC;

EID: 0037335444     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.23-05-01710.2003     Document Type: Article
Times cited : (115)

References (48)
  • 1
    • 0030803271 scopus 로고    scopus 로고
    • Bcl-2 and the outer mitochondrial membrane in the inactivation of cytochrome c during Fasmediated apoptosis
    • Adachi S, Cross AR, Babior BM, Gottlieb RA (1997) Bcl-2 and the outer mitochondrial membrane in the inactivation of cytochrome c during Fasmediated apoptosis. J Biol Chem 272:21878-21882.
    • (1997) J Biol Chem , vol.272 , pp. 21878-21882
    • Adachi, S.1    Cross, A.R.2    Babior, B.M.3    Gottlieb, R.A.4
  • 2
    • 0029039139 scopus 로고
    • - in vascular smooth muscle cells
    • - in vascular smooth muscle cells. Circ Res 77:29-36.
    • (1995) Circ Res , vol.77 , pp. 29-36
    • Baas, A.S.1    Berk, B.C.2
  • 3
    • 0032698075 scopus 로고    scopus 로고
    • Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and -independent mechanisms
    • Bonni A, Brunet A, West AE, Datta SR, Takasu MA, Greenberg ME (1999) Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and -independent mechanisms. Science 286: 1358-1362.
    • (1999) Science , vol.286 , pp. 1358-1362
    • Bonni, A.1    Brunet, A.2    West, A.E.3    Datta, S.R.4    Takasu, M.A.5    Greenberg, M.E.6
  • 4
    • 0015882341 scopus 로고
    • The mitochondrial generation of hydrogen peroxide. General properties and effect of hyperbaric oxygen
    • Boveris A, Chance B (1973) The mitochondrial generation of hydrogen peroxide. General properties and effect of hyperbaric oxygen. Biochem J 134:707-716.
    • (1973) Biochem J , vol.134 , pp. 707-716
    • Boveris, A.1    Chance, B.2
  • 5
    • 0029160069 scopus 로고
    • Protein kinase B (c-Akt) in phosphatidylinositol 3-OH kinase signal transduction
    • Burgering BM, Coffer PJ (1995) Protein kinase B (c-Akt) in phosphatidylinositol 3-OH kinase signal transduction. Nature 376:599-602.
    • (1995) Nature , vol.376 , pp. 599-602
    • Burgering, B.M.1    Coffer, P.J.2
  • 6
    • 0035045290 scopus 로고    scopus 로고
    • Intracellular Bax translocation after transient cerebral ischemia: Implications for a role of the mitochondrial apoptotic signaling pathway in ischemic neuronal death
    • Cao G, Minami M, Pei W, Yan C, Chen D, O'Horo C, Graham SH, Chen J (2001) Intracellular Bax translocation after transient cerebral ischemia: implications for a role of the mitochondrial apoptotic signaling pathway in ischemic neuronal death. J Cereb Blood Flow Metab 21:321-333.
    • (2001) J Cereb Blood Flow Metab , vol.21 , pp. 321-333
    • Cao, G.1    Minami, M.2    Pei, W.3    Yan, C.4    Chen, D.5    O'Horo, C.6    Graham, S.H.7    Chen, J.8
  • 7
    • 0031460627 scopus 로고    scopus 로고
    • Protein kinases A and C are involved in the mechanisms underlying consolidation of cocaine place conditioning
    • Cervo L, Mukherjee S, Bertaglia A, Samanin R (1997) Protein kinases A and C are involved in the mechanisms underlying consolidation of cocaine place conditioning. Brain Res 775:30-36.
    • (1997) Brain Res , vol.775 , pp. 30-36
    • Cervo, L.1    Mukherjee, S.2    Bertaglia, A.3    Samanin, R.4
  • 8
    • 0028280865 scopus 로고
    • Oxygen radicals in focal cerebral ischemia
    • Chan PH (1994) Oxygen radicals in focal cerebral ischemia. Brain Pathol 4:59-65.
    • (1994) Brain Pathol , vol.4 , pp. 59-65
    • Chan, P.H.1
  • 9
    • 0029888311 scopus 로고    scopus 로고
    • Role of oxidants in ischemic brain damage
    • Chan PH (1996) Role of oxidants in ischemic brain damage. Stroke 27:1124-1129.
    • (1996) Stroke , vol.27 , pp. 1124-1129
    • Chan, P.H.1
  • 10
    • 0033635235 scopus 로고    scopus 로고
    • 14-3-3 Proteins and survival kinases cooperate to inactivate BAD by BH3 domain phosphorylation
    • Datta SR, Katsov A, Hu L, Petros A, Fesik SW, Yaffe MB, Greenberg ME (2000) 14-3-3 proteins and survival kinases cooperate to inactivate BAD by BH3 domain phosphorylation. Mol Cell 6:41-51.
    • (2000) Mol Cell , vol.6 , pp. 41-51
    • Datta, S.R.1    Katsov, A.2    Hu, L.3    Petros, A.4    Fesik, S.W.5    Yaffe, M.B.6    Greenberg, M.E.7
  • 12
    • 0030907987 scopus 로고    scopus 로고
    • PI3K: Downstream AKTion blocks apoptosis
    • Flanke TF, Kaplan DR, Cantley LC (1999) PI3K: downstream AKTion blocks apoptosis. Cell 88:435-437.
    • (1999) Cell , vol.88 , pp. 435-437
    • Flanke, T.F.1    Kaplan, D.R.2    Cantley, L.C.3
  • 13
    • 0033135367 scopus 로고    scopus 로고
    • Manganese superoxide dismutase mediates the early release of mitochondrial cytochrome c and subsequent DNA fragmentation after permanent focal cerebral ischemia in mice
    • Fujimura M, Morita-Fujimura Y, Kawase M, Copin J-C, Calagui B, Epstein CJ, Chan PH (1999) Manganese superoxide dismutase mediates the early release of mitochondrial cytochrome c and subsequent DNA fragmentation after permanent focal cerebral ischemia in mice. J Neurosci 19:3414-3422.
    • (1999) J Neurosci , vol.19 , pp. 3414-3422
    • Fujimura, M.1    Morita-Fujimura, Y.2    Kawase, M.3    Copin, J.-C.4    Calagui, B.5    Epstein, C.J.6    Chan, P.H.7
  • 14
    • 0034655765 scopus 로고    scopus 로고
    • The cytosolic antioxidant copper/zinc-superoxide dismutase prevents the early release of mitochondrial cytochrome c in ischemic brain after transient focal cerebral ischemia in mice
    • Fujimura M, Morita-Fujimura Y, Noshita N, Sugawara T, Kawase M, Chan PH (2000) The cytosolic antioxidant copper/zinc-superoxide dismutase prevents the early release of mitochondrial cytochrome c in ischemic brain after transient focal cerebral ischemia in mice. J Neurosci 20:2817-2824.
    • (2000) J Neurosci , vol.20 , pp. 2817-2824
    • Fujimura, M.1    Morita-Fujimura, Y.2    Noshita, N.3    Sugawara, T.4    Kawase, M.5    Chan, P.H.6
  • 16
    • 0036829062 scopus 로고    scopus 로고
    • Antioxidant and pro-oxidant mechanisms in the regulation of redox(y)-sensitive transcription factors
    • Haddad JJ (2002) Antioxidant and pro-oxidant mechanisms in the regulation of redox(y)-sensitive transcription factors. Cell Signal 14:879-897.
    • (2002) Cell Signal , vol.14 , pp. 879-897
    • Haddad, J.J.1
  • 17
    • 0033529638 scopus 로고    scopus 로고
    • Neuroprotection by brain-derived neurotrophic factor is mediated by extracellular signal-regulated kinase and phosphatidylinositol 3-kinase
    • Hetman M, Kanning K, Cavanaugh JE, Xia Z (1999) Neuroprotection by brain-derived neurotrophic factor is mediated by extracellular signal-regulated kinase and phosphatidylinositol 3-kinase. J Biol Chem 274:22569-22580.
    • (1999) J Biol Chem , vol.274 , pp. 22569-22580
    • Hetman, M.1    Kanning, K.2    Cavanaugh, J.E.3    Xia, Z.4
  • 18
    • 2142721829 scopus 로고    scopus 로고
    • L/Bcl-2-associated death promoter)-induced apoptosis in mammalian cells by 14-3-3 isoforms and P11
    • L/Bcl-2-associated death promoter)-induced apoptosis in mammalian cells by 14-3-3 isoforms and P11. Mol Endocrinol 11:1858-1867.
    • (1997) Mol Endocrinol , vol.11 , pp. 1858-1867
    • Hsu, S.Y.1    Kaipia, A.2    Zhu, L.3    Hsueh, A.J.W.4
  • 19
    • 0037135568 scopus 로고    scopus 로고
    • Transforming growth factor-Β induces expression of receptor activator of NF-κB ligand in vascular endothelial cells derived from bone
    • Ishida A, Fujita N, Kitazawa R, Tsuruo T (2002) Transforming growth factor-β induces expression of receptor activator of NF-κB ligand in vascular endothelial cells derived from bone. J Biol Chem 277:26217-26224.
    • (2002) J Biol Chem , vol.277 , pp. 26217-26224
    • Ishida, A.1    Fujita, N.2    Kitazawa, R.3    Tsuruo, T.4
  • 21
    • 0032146987 scopus 로고    scopus 로고
    • Bcl-2 family proteins: The role of the BH3 domain in apoptosis
    • Kelekar A, Thompson CB (1998) Bcl-2 family proteins: the role of the BH3 domain in apoptosis. Trends Cell Biol 8:324-330.
    • (1998) Trends Cell Biol , vol.8 , pp. 324-330
    • Kelekar, A.1    Thompson, C.B.2
  • 22
    • 0032213268 scopus 로고    scopus 로고
    • cAMP-dependent long-term potentiation of nitric oxide release from cerebellar parallel fibers in rats
    • Kimura S, Uchiyama S, Takahashi HE, Shibuki K (1998) cAMP-dependent long-term potentiation of nitric oxide release from cerebellar parallel fibers in rats. J Neurosci 18:8551-8558.
    • (1998) J Neurosci , vol.18 , pp. 8551-8558
    • Kimura, S.1    Uchiyama, S.2    Takahashi, H.E.3    Shibuki, K.4
  • 23
    • 0026345023 scopus 로고
    • Attenuation of focal cerebral ischemic injury in transgenic mice overexpressing Cu/Zn superoxide dismutase
    • Kinouchi H, Epstein CJ, Mizui T, Carlson E, Chen SF, Chan PH (1991) Attenuation of focal cerebral ischemic injury in transgenic mice overexpressing Cu/Zn superoxide dismutase. Proc Natl Acad Sci USA 88:11158-11162.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 11158-11162
    • Kinouchi, H.1    Epstein, C.J.2    Mizui, T.3    Carlson, E.4    Chen, S.F.5    Chan, P.H.6
  • 25
    • 0030916669 scopus 로고    scopus 로고
    • The proto-oncogene Bcl-2 and its role in regulating apoptosis
    • Kroemer G (1997) The proto-oncogene Bcl-2 and its role in regulating apoptosis. Nat Med 3:614-620.
    • (1997) Nat Med , vol.3 , pp. 614-620
    • Kroemer, G.1
  • 26
    • 0003001918 scopus 로고    scopus 로고
    • Differentiation between apoptotic and necrotic cell death by means of the BM cell death detection ELISA or annexin V staining
    • Leist M, Kuhnle S, Single B, Nicotera P (1998) Differentiation between apoptotic and necrotic cell death by means of the BM cell death detection ELISA or annexin V staining. Biochemica 2:25-28.
    • (1998) Biochemica , vol.2 , pp. 25-28
    • Leist, M.1    Kuhnle, S.2    Single, B.3    Nicotera, P.4
  • 27
    • 0030715323 scopus 로고    scopus 로고
    • Cytochrome c and d ATP-dependent formation of Apaf1/caspase-9 complex initiates an apoptotic protease cascade
    • Li P, Nijhawan D, Budihardjo I, Srinivasula SM, Ahmad M, Alnemri ES, Wang X (1997) Cytochrome c and d ATP-dependent formation of Apaf1/caspase-9 complex initiates an apoptotic protease cascade. Cell 91:479-489.
    • (1997) Cell , vol.91 , pp. 479-489
    • Li, P.1    Nijhawan, D.2    Budihardjo, I.3    Srinivasula, S.M.4    Ahmad, M.5    Alnemri, E.S.6    Wang, X.7
  • 28
    • 0034661857 scopus 로고    scopus 로고
    • Regulation of BAD by cAMP-dependent protein kinase is mediated via phosphorylation of a novel site, Ser-155
    • Lizcano JM, Morrice N, Cohen P (2000) Regulation of BAD by cAMP-dependent protein kinase is mediated via phosphorylation of a novel site, Ser-155. Biochem J 349:547-557.
    • (2000) Biochem J , vol.349 , pp. 547-557
    • Lizcano, J.M.1    Morrice, N.2    Cohen, P.3
  • 29
    • 0030794929 scopus 로고    scopus 로고
    • Overexpression of Cu/Zn-superoxide dismutase reduces hippocampal injury after global ischemia in transgenic mice
    • Murakami K, Kondo T, Epstein CJ, Chan PH (1997) Overexpression of Cu/Zn-superoxide dismutase reduces hippocampal injury after global ischemia in transgenic mice. Stroke 28:1797-1804.
    • (1997) Stroke , vol.28 , pp. 1797-1804
    • Murakami, K.1    Kondo, T.2    Epstein, C.J.3    Chan, P.H.4
  • 30
    • 0032422488 scopus 로고    scopus 로고
    • Bax interacts with the permeability transition pore to induce permeability transition and cytochrome c release in isolated mitochondria
    • Narita M, Shimizu S, Ito T, Chittenden T, Lutz RJ, Matsuda H, Tsujimoto Y (1998) Bax interacts with the permeability transition pore to induce permeability transition and cytochrome c release in isolated mitochondria. Proc Natl Acad Sci USA 95:14681-14686.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 14681-14686
    • Narita, M.1    Shimizu, S.2    Ito, T.3    Chittenden, T.4    Lutz, R.J.5    Matsuda, H.6    Tsujimoto, Y.7
  • 31
    • 0037107185 scopus 로고    scopus 로고
    • Copper/zinc superoxide dismutase attenuates neuronal cell death by preventing extracellular signal-regulated kinase activation after transient focal cerebral ischemia in mice
    • Noshita N, Sugawara T, Hayashi T, Lewén A, Omar G, Chan PH (2002) Copper/zinc superoxide dismutase attenuates neuronal cell death by preventing extracellular signal-regulated kinase activation after transient focal cerebral ischemia in mice. J Neurosci 22:7923-7930.
    • (2002) J Neurosci , vol.22 , pp. 7923-7930
    • Noshita, N.1    Sugawara, T.2    Hayashi, T.3    Lewén, A.4    Omar, G.5    Chan, P.H.6
  • 32
    • 0033516674 scopus 로고    scopus 로고
    • Tumor necrosis factor induces phosphorylation and translocation of Bad through a phosphatidylinositide-3-OH kinase-dependent pathway
    • Pastorino JG, Tafani M, Farber JL (1999) Tumor necrosis factor induces phosphorylation and translocation of Bad through a phosphatidylinositide-3-OH kinase-dependent pathway. J Biol Chem 274:19411-19416.
    • (1999) J Biol Chem , vol.274 , pp. 19411-19416
    • Pastorino, J.G.1    Tafani, M.2    Farber, J.L.3
  • 33
    • 0030979773 scopus 로고    scopus 로고
    • Double identity for proteins of the Bcl-2 family
    • Reed JC (1997) Double identity for proteins of the Bcl-2 family. Nature 387:773-776.
    • (1997) Nature , vol.387 , pp. 773-776
    • Reed, J.C.1
  • 37
    • 0034307421 scopus 로고    scopus 로고
    • Calcineurin-mediated BAD dephosphorylation activates the caspase-3 apoptotic cascade in traumatic spinal cord injury
    • Springer JE, Azbill RD, Nottingham SA, Kennedy SE (2000) Calcineurin-mediated BAD dephosphorylation activates the caspase-3 apoptotic cascade in traumatic spinal cord injury. J Neurosci 20:7246-7251.
    • (2000) J Neurosci , vol.20 , pp. 7246-7251
    • Springer, J.E.1    Azbill, R.D.2    Nottingham, S.A.3    Kennedy, S.E.4
  • 38
    • 0036138386 scopus 로고    scopus 로고
    • Overexpression of copper/zinc superoxide dismutase in transgenic rats protects vulnerable neurons against ischemic damage by blocking the mitochondrial pathway of caspase activation
    • Sugawara T, Noshita N, Lewén A, Gasche Y, Ferrand-Drake M, Fujimura M, Morita-Fujimura Y, Chan PH (2002) Overexpression of copper/zinc superoxide dismutase in transgenic rats protects vulnerable neurons against ischemic damage by blocking the mitochondrial pathway of caspase activation. J Neurosci 22:209-217.
    • (2002) J Neurosci , vol.22 , pp. 209-217
    • Sugawara, T.1    Noshita, N.2    Lewén, A.3    Gasche, Y.4    Ferrand-Drake, M.5    Fujimura, M.6    Morita-Fujimura, Y.7    Chan, P.H.8
  • 39
    • 0033520937 scopus 로고    scopus 로고
    • RSK blocks Bad-mediated cell death via a protein kinase C-dependent pathway
    • RSK blocks Bad-mediated cell death via a protein kinase C-dependent pathway. J Biol Chem 274:34859-34867.
    • (1999) J Biol Chem , vol.274 , pp. 34859-34867
    • Tan, Y.1    Ruan, H.2    Demeter, M.R.3    Comb, M.J.4
  • 41
    • 0032478791 scopus 로고    scopus 로고
    • Transforming growth factor-β1 stimulates protein kinase A in mesangial cells
    • Wang L, Zhu Y, Sharma K (1998) Transforming growth factor-β1 stimulates protein kinase A in mesangial cells. J Biol Chem 273:8522-8527.
    • (1998) J Biol Chem , vol.273 , pp. 8522-8527
    • Wang, L.1    Zhu, Y.2    Sharma, K.3
  • 42
    • 0029899181 scopus 로고    scopus 로고
    • Molecular thanatopsis: A discourse on the BCL2 family and cell death
    • Yang E, Korsmeyer SJ (1996) Molecular thanatopsis: a discourse on the BCL2 family and cell death. Blood 88:386-401.
    • (1996) Blood , vol.88 , pp. 386-401
    • Yang, E.1    Korsmeyer, S.J.2
  • 44
    • 0028040278 scopus 로고
    • Human copper/zinc superoxide dismutase transgenic mice are highly resistant to reperfusion injury after focal cerebral ischemia
    • Yang G, Chan PH, Chen J, Carlson E, Chen SF, Weinstein P, Epstein CJ, Kamii H (1994) Human copper/zinc superoxide dismutase transgenic mice are highly resistant to reperfusion injury after focal cerebral ischemia. Stroke 25:165-170.
    • (1994) Stroke , vol.25 , pp. 165-170
    • Yang, G.1    Chan, P.H.2    Chen, J.3    Carlson, E.4    Chen, S.F.5    Weinstein, P.6    Epstein, C.J.7    Kamii, H.8
  • 46
    • 0033587773 scopus 로고    scopus 로고
    • Suppression of apoptosis signal-regulating kinase 1-induced cell death by 14-3-3 proteins
    • Zhang L, Chen J, Fu H (1999) Suppression of apoptosis signal-regulating kinase 1-induced cell death by 14-3-3 proteins. Proc Natl Acad Sci USA 96:8511-8515.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 8511-8515
    • Zhang, L.1    Chen, J.2    Fu, H.3
  • 48
    • 0033607633 scopus 로고    scopus 로고
    • Phosphorylation and regulation of Raf by Akt (protein kinase B)
    • Zimmermann S, Moelling K (1999) Phosphorylation and regulation of Raf by Akt (protein kinase B). Science 286:1741-1744.
    • (1999) Science , vol.286 , pp. 1741-1744
    • Zimmermann, S.1    Moelling, K.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.