메뉴 건너뛰기




Volumn 1, Issue 5, 2003, Pages 1103-1111

Modulation of Rho GTPase activity in endothelial cells by selective proteinase-activated receptor (PAR) agonists

Author keywords

Endothelial cells; Protease activated receptors; Rho

Indexed keywords


EID: 1842494553     PISSN: 15387933     EISSN: 15387836     Source Type: Journal    
DOI: 10.1046/j.1538-7836.2003.00238.x     Document Type: Article
Times cited : (42)

References (51)
  • 1
    • 0035952643 scopus 로고    scopus 로고
    • Protease activated receptors: theme and variations
    • O'Brien PJ, Molino M, Kahn M, Brass LF. Protease activated receptors: theme and variations. Oncogene 2001; 20: 1570-81.
    • (2001) Oncogene , vol.20 , pp. 1570-1581
    • O'Brien, P.J.1    Molino, M.2    Kahn, M.3    Brass, L.F.4
  • 2
    • 0034921205 scopus 로고    scopus 로고
    • Protease-activated receptors in vascular biology
    • Coughlin SR. Protease-activated receptors in vascular biology. Thromb Haemost 2001; 86: 298-307.
    • (2001) Thromb Haemost , vol.86 , pp. 298-307
    • Coughlin, S.R.1
  • 4
    • 0035979691 scopus 로고    scopus 로고
    • A role for thrombin receptor signaling in endothelial cells during embryonic development
    • Griffin CT, Srinivasan Y, Zheng YW, Huang W, Coughlin SR. A role for thrombin receptor signaling in endothelial cells during embryonic development. Science 2001; 293: 1666-70.
    • (2001) Science , vol.293 , pp. 1666-1670
    • Griffin, C.T.1    Srinivasan, Y.2    Zheng, Y.W.3    Huang, W.4    Coughlin, S.R.5
  • 6
    • 0020597838 scopus 로고
    • Thrombin-induced lung vascular injury. Roles of fibrinogen and fibrinolysis
    • Johnson A, Tahamont MV, Malik AB. Thrombin-induced lung vascular injury. Roles of fibrinogen and fibrinolysis. Am Rev Respir Dis 1983; 128: 38-44.
    • (1983) Am Rev Respir Dis , vol.128 , pp. 38-44
    • Johnson, A.1    Tahamont, M.V.2    Malik, A.B.3
  • 7
    • 0021889823 scopus 로고
    • Thrombin-induced alterations in lung fluid balance in awake sheep
    • Lo SK, Perlman MB, Niehaus GD, Malik AB. Thrombin-induced alterations in lung fluid balance in awake sheep. J Appl Physiol 1985; 58: 1421-7.
    • (1985) J Appl Physiol , vol.58 , pp. 1421-1427
    • Lo, S.K.1    Perlman, M.B.2    Niehaus, G.D.3    Malik, A.B.4
  • 8
    • 0029803695 scopus 로고    scopus 로고
    • Regulation of thrombin-mediated endothelial cell contraction and permeability
    • Garcia JG, Verin AD, Schaphorst KL. Regulation of thrombin-mediated endothelial cell contraction and permeability. Semin Thromb Hemost 1996; 22: 309-15.
    • (1996) Semin Thromb Hemost , vol.22 , pp. 309-315
    • Garcia, J.G.1    Verin, A.D.2    Schaphorst, K.L.3
  • 10
    • 0032555506 scopus 로고    scopus 로고
    • Thrombin inactivates myosin light chain phosphatase via Rho and its target Rho kinase in human endothelial cells
    • Essler M, Amano M, Kruse HJ, Kaibuchi K, Weber PC, Aepfelbacher M. Thrombin inactivates myosin light chain phosphatase via Rho and its target Rho kinase in human endothelial cells. J Biol Chem 1998; 273: 21867-74.
    • (1998) J Biol Chem , vol.273 , pp. 21867-21874
    • Essler, M.1    Amano, M.2    Kruse, H.J.3    Kaibuchi, K.4    Weber, P.C.5    Aepfelbacher, M.6
  • 11
    • 0032583083 scopus 로고    scopus 로고
    • Transient and prolonged increase in endothelial permeability induced by histamine and thrombin: role of protein kinases, calcium, and RhoA
    • van Nieuw Amerongen GP, Draijer R, Vermeer MA, van HinsberghVW. Transient and prolonged increase in endothelial permeability induced by histamine and thrombin: role of protein kinases, calcium, and RhoA. Circ Res 1998; 83: 1115-23.
    • (1998) Circ Res , vol.83 , pp. 1115-1123
    • van Nieuw Amerongen, G.P.1    Draijer, R.2    Vermeer, M.A.3    van Hinsbergh, V.W.4
  • 12
    • 0031717365 scopus 로고    scopus 로고
    • Regulation of the actin cytoskeleton by thrombin in human endothelial cells: role of Rho proteins in endothelial barrier function
    • Vouret-Craviari V, Boquet P, Pouyssegur J, Van Obberghen-Schilling E. Regulation of the actin cytoskeleton by thrombin in human endothelial cells: role of Rho proteins in endothelial barrier function. Mol Biol Cell 1998; 9: 2639-53.
    • (1998) Mol Biol Cell , vol.9 , pp. 2639-2653
    • Vouret-Craviari, V.1    Boquet, P.2    Pouyssegur, J.3    Van Obberghen-Schilling, E.4
  • 13
    • 0032738144 scopus 로고    scopus 로고
    • RhoA inactivation enhances endothelial barrier function
    • Carbajal JM, Schaeffer RC Jr. RhoA inactivation enhances endothelial barrier function. Am J Physiol 1999; 277: C955-64.
    • (1999) Am J Physiol , vol.277
    • Carbajal, J.M.1    Schaeffer Jr., R.C.2
  • 15
    • 0030003829 scopus 로고    scopus 로고
    • The proteinase activated receptor-2 (PAR-2) mediates mitogenic responses in human vascular endothelial cells
    • Mirza H, Yatsula V, Bahou WF. The proteinase activated receptor-2 (PAR-2) mediates mitogenic responses in human vascular endothelial cells. J Clin Invest 1996; 97: 1705-14.
    • (1996) J Clin Invest , vol.97 , pp. 1705-1714
    • Mirza, H.1    Yatsula, V.2    Bahou, W.F.3
  • 16
    • 15844401726 scopus 로고    scopus 로고
    • The proteinase-activated receptor 2 is induced by inflammatory mediators in human endothelial cells. Comparison with the thrombin receptor
    • Nystedt S, Ramakrishnan V, Sundelin J. The proteinase-activated receptor 2 is induced by inflammatory mediators in human endothelial cells. Comparison with the thrombin receptor. J Biol Chem 1996; 271: 14910-5.
    • (1996) J Biol Chem , vol.271 , pp. 14910-14915
    • Nystedt, S.1    Ramakrishnan, V.2    Sundelin, J.3
  • 18
    • 0034161592 scopus 로고    scopus 로고
    • Protease-activated receptors: sentries for inflammation?
    • Cocks TM, Moffatt JD. Protease-activated receptors: sentries for inflammation? Trends Pharmacol Sci 2000; 21: 103-8.
    • (2000) Trends Pharmacol Sci , vol.21 , pp. 103-108
    • Cocks, T.M.1    Moffatt, J.D.2
  • 19
    • 0031690091 scopus 로고    scopus 로고
    • Increased vascular permeability by a specific agonist of protease-activated receptor-2 in rat hindpaw
    • Kawabata A, Kuroda R, Minami T, Kataoka K, Taneda M. Increased vascular permeability by a specific agonist of protease-activated receptor-2 in rat hindpaw. Br J Pharmacol 1998; 125: 419-22.
    • (1998) Br J Pharmacol , vol.125 , pp. 419-422
    • Kawabata, A.1    Kuroda, R.2    Minami, T.3    Kataoka, K.4    Taneda, M.5
  • 20
    • 0032792955 scopus 로고    scopus 로고
    • Characterization of the inflammatory response to proteinase-activated receptor-2 (PAR2)-activating peptides in the rat paw
    • Vergnolle N, Hollenberg MD, Sharkey KA,Wallace JL. Characterization of the inflammatory response to proteinase-activated receptor-2 (PAR2)-activating peptides in the rat paw. Br J Pharmacol 1999; 127: 1083-90.
    • (1999) Br J Pharmacol , vol.127 , pp. 1083-1090
    • Vergnolle, N.1    Hollenberg, M.D.2    Sharkey, K.A.3    Wallace, J.L.4
  • 22
    • 0030667055 scopus 로고    scopus 로고
    • Proteaseactivated receptors: development of agonists selective for receptors triggered by either thrombin (PAR1) or trypsin (Par2)
    • Kawabata A, Saifeddine M, Al-Ani B, Hollenberg MD. Proteaseactivated receptors: development of agonists selective for receptors triggered by either thrombin (PAR1) or trypsin (Par2). Proc West Pharmacol Soc 1997; 40: 49-51.
    • (1997) Proc West Pharmacol Soc , vol.40 , pp. 49-51
    • Kawabata, A.1    Saifeddine, M.2    Al-Ani, B.3    Hollenberg, M.D.4
  • 24
    • 0019782707 scopus 로고
    • Evidence that vascular endothelial cells can induce the retraction of fibrin clot
    • Barbieri B, Balconi G, Dejana B, Donati MB. Evidence that vascular endothelial cells can induce the retraction of fibrin clot. Proc Soc Exp Biol Med 1981; 168: 204-7.
    • (1981) Proc Soc Exp Biol Med , vol.168 , pp. 204-207
    • Barbieri, B.1    Balconi, G.2    Dejana, B.3    Donati, M.B.4
  • 26
    • 0037096160 scopus 로고    scopus 로고
    • Distinct signals via Rho GTPases and Src drive shape changes by thrombin and sphingosine-1-phosphate in endothelial cells
    • Vouret-Craviari V, Bourcier C, Boulter E, Van Obberghen-Schilling E. Distinct signals via Rho GTPases and Src drive shape changes by thrombin and sphingosine-1-phosphate in endothelial cells. J Cell Sci 2002; 115: 2475-84.
    • (2002) J Cell Sci , vol.115 , pp. 2475-2484
    • Vouret-Craviari, V.1    Bourcier, C.2    Boulter, E.3    Van Obberghen-Schilling, E.4
  • 27
    • 84940142489 scopus 로고
    • Vascular reactions to histamine, histamine-liberator and leukotaxine in the skin of guinea pigs
    • Miles AA,Miles EF. Vascular reactions to histamine, histamine-liberator and leukotaxine in the skin of guinea pigs. J Physiol 1952; 118: 228-57.
    • (1952) J Physiol , vol.118 , pp. 228-257
    • Miles, A.A.1    Miles, E.F.2
  • 28
    • 0033121275 scopus 로고    scopus 로고
    • The role of alpha integrins during angiogenesis: insights into potential mechanisms of action and clinical development
    • Eliceiri BP, Cheresh DA. The role of alpha integrins during angiogenesis: insights into potential mechanisms of action and clinical development. J Clin Invest 1999; 103: 1227-30.
    • (1999) J Clin Invest , vol.103 , pp. 1227-1230
    • Eliceiri, B.P.1    Cheresh, D.A.2
  • 29
    • 0034213327 scopus 로고    scopus 로고
    • Rho GTPases and their effector proteins
    • Bishop AL, Hall A. Rho GTPases and their effector proteins. Biochem J 2000; 348: 241-55.
    • (2000) Biochem J , vol.348 , pp. 241-255
    • Bishop, A.L.1    Hall, A.2
  • 30
    • 0035575585 scopus 로고    scopus 로고
    • Rho family proteins: coordinating cell responses
    • Ridley AJ. Rho family proteins: coordinating cell responses. Trends Cell Biol 2001; 11: 471-7.
    • (2001) Trends Cell Biol , vol.11 , pp. 471-477
    • Ridley, A.J.1
  • 31
    • 0033081753 scopus 로고    scopus 로고
    • Regulation of the small GTPbinding protein Rho by cell adhesion and the cytoskeleton
    • Ren XD, Kiosses WB, Schwartz MA. Regulation of the small GTPbinding protein Rho by cell adhesion and the cytoskeleton. EMBO J 1999; 18: 578-85.
    • (1999) EMBO J , vol.18 , pp. 578-585
    • Ren, X.D.1    Kiosses, W.B.2    Schwartz, M.A.3
  • 33
    • 0034597092 scopus 로고    scopus 로고
    • Cortactin localization to sites of actin assembly in lamellipodia requires interactions with F-actin and the Arp2/3 complex
    • Weed SA, Karginov AV, Schafer DA, Weaver AM, Kinley AW, Cooper JA, Parsons JT. Cortactin localization to sites of actin assembly in lamellipodia requires interactions with F-actin and the Arp2/3 complex. J Cell Biol 2000; 151: 29-40.
    • (2000) J Cell Biol , vol.151 , pp. 29-40
    • Weed, S.A.1    Karginov, A.V.2    Schafer, D.A.3    Weaver, A.M.4    Kinley, A.W.5    Cooper, J.A.6    Parsons, J.T.7
  • 34
    • 0034644109 scopus 로고    scopus 로고
    • Adhesion signaling: PAK meets Rac on solid ground
    • Symons M. Adhesion signaling: PAK meets Rac on solid ground. Curr Biol 2000; 10: R535-7.
    • (2000) Curr Biol , vol.10
    • Symons, M.1
  • 35
    • 0036644975 scopus 로고    scopus 로고
    • Guanine nucleotide exchange factors for Rho GTPases: turning on the switch
    • Schmidt A, Hall A. Guanine nucleotide exchange factors for Rho GTPases: turning on the switch. Genes Dev 2002; 16: 1587-609.
    • (2002) Genes Dev , vol.16 , pp. 1587-1609
    • Schmidt, A.1    Hall, A.2
  • 36
    • 0037075886 scopus 로고    scopus 로고
    • GTPase activating proteins: critical regulators of intracellular signaling
    • Donovan S, Shannon KM, Bollag G. GTPase activating proteins: critical regulators of intracellular signaling. Biochim Biophys Acta 2002; 1602: 23-45.
    • (2002) Biochim Biophys Acta , vol.1602 , pp. 23-45
    • Donovan, S.1    Shannon, K.M.2    Bollag, G.3
  • 37
    • 0033578621 scopus 로고    scopus 로고
    • A rho exchange factor mediates thrombin and Galpha (12)-induced cytoskeletal responses
    • Majumdar M, Seasholtz TM, Buckmaster C, Toksoz D, Brown JH. A rho exchange factor mediates thrombin and Galpha (12)-induced cytoskeletal responses. J Biol Chem 1999; 274: 26815-21.
    • (1999) J Biol Chem , vol.274 , pp. 26815-26821
    • Majumdar, M.1    Seasholtz, T.M.2    Buckmaster, C.3    Toksoz, D.4    Brown, J.H.5
  • 38
    • 0035952680 scopus 로고    scopus 로고
    • RGS-containing RhoGEFs. the missing link between transforming G proteins and Rho?
    • Fukuhara S, Chikumi H, Gutkind JS. RGS-containing RhoGEFs. the missing link between transforming G proteins and Rho? Oncogene 2001; 20: 1661-8.
    • (2001) Oncogene , vol.20 , pp. 1661-1668
    • Fukuhara, S.1    Chikumi, H.2    Gutkind, J.S.3
  • 41
    • 0037023691 scopus 로고    scopus 로고
    • Regulation of G protein-linked guanine nucleotide exchange factors for Rho, PDZ-RhoGEF, and LARG by tyrosine phosphorylation: evidence of a role for focal adhesion kinase
    • Chikumi H, Fukuhara S, Gutkind JS. Regulation of G protein-linked guanine nucleotide exchange factors for Rho, PDZ-RhoGEF, and LARG by tyrosine phosphorylation: evidence of a role for focal adhesion kinase. J Biol Chem 2002; 277: 12463-73.
    • (2002) J Biol Chem , vol.277 , pp. 12463-12473
    • Chikumi, H.1    Fukuhara, S.2    Gutkind, J.S.3
  • 42
    • 0032943041 scopus 로고    scopus 로고
    • Endothelial protease-activated receptor-2 induces tissue factor expression and von Willebrand factor release
    • Langer F, Morys-Wortmann C, Kusters B, Storck J. Endothelial protease-activated receptor-2 induces tissue factor expression and von Willebrand factor release. Br J Haematol 1999; 105: 542-50.
    • (1999) Br J Haematol , vol.105 , pp. 542-550
    • Langer, F.1    Morys-Wortmann, C.2    Kusters, B.3    Storck, J.4
  • 43
    • 0034142240 scopus 로고    scopus 로고
    • Activation of the small GTPases, rac and cdc42, after ligation of the platelet PAR-1 receptor
    • Azim AC, Barkalow K, Chou J, Hartwig JH. Activation of the small GTPases, rac and cdc42, after ligation of the platelet PAR-1 receptor. Blood 2000; 95: 959-64.
    • (2000) Blood , vol.95 , pp. 959-964
    • Azim, A.C.1    Barkalow, K.2    Chou, J.3    Hartwig, J.H.4
  • 48
    • 0033393771 scopus 로고    scopus 로고
    • Selective requirement for Src kinases during VEGF-induced angiogenesis and vascular permeability. PG - 915-24
    • Eliceiri BP, Paul R, Schwartzberg PL, Hood JD, Leng J, Cheresh DA. Selective requirement for Src kinases during VEGF-induced angiogenesis and vascular permeability. PG - 915-24. Mol Cell 1999; 4: 915-24.
    • (1999) Mol Cell , vol.4 , pp. 915-924
    • Eliceiri, B.P.1    Paul, R.2    Schwartzberg, P.L.3    Hood, J.D.4    Leng, J.5    Cheresh, D.A.6
  • 49
    • 0037119446 scopus 로고    scopus 로고
    • Complete structure of an increasing capillary permeability protein (ICPP) purified from Vipera lebetina venom. ICPP is angiogenic via vascular endothelial growth factor receptor signalling
    • Gasmi A, Bourcier C, Aloui Z, Srairi N, Marchetti S, Gimond C,Wedge SR, Hennequin L, Pouyssegur J. Complete structure of an increasing capillary permeability protein (ICPP) purified from Vipera lebetina venom. ICPP is angiogenic via vascular endothelial growth factor receptor signalling J Biol Chem 2002; 277: 29992-8.
    • (2002) J Biol Chem , vol.277 , pp. 29992-29998
    • Gasmi, A.1    Bourcier, C.2    Aloui, Z.3    Srairi, N.4    Marchetti, S.5    Gimond, C.6    Wedge, S.R.7    Hennequin, L.8    Pouyssegur, J.9
  • 51
    • 0035816730 scopus 로고    scopus 로고
    • Increased expression of protease-activated receptor-2 (PAR2) and PAR4 in human coronary artery by inflammatory stimuli unveils endothelium-dependent relaxations to PAR2 and PAR4 agonists
    • Hamilton JR, Frauman AG, Cocks TM. Increased expression of protease-activated receptor-2 (PAR2) and PAR4 in human coronary artery by inflammatory stimuli unveils endothelium-dependent relaxations to PAR2 and PAR4 agonists. Circ Res 2001; 89: 92-8.
    • (2001) Circ Res , vol.89 , pp. 92-98
    • Hamilton, J.R.1    Frauman, A.G.2    Cocks, T.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.