Protease-activated receptors. development of agonists selective for receptors triggered by either thrombin (pari) or trypsin (PAR2)

Proceedings of the Western Pharmacology Society

Volumn 40, Issue , 1997, Pages 49-51

  Kawabata, A ^a   Saifeddine, M ^b   Al Ani, B ^b   Hollenberg, M D ^b  

^a UNIVERSITY OF CALGARY   (Canada)

^b KINKI UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

GUANINE NUCLEOTIDE BINDING PROTEIN; PROTEINASE; RECEPTOR PROTEIN; THROMBIN; THROMBIN RECEPTOR; TRYPSIN;

ARTICLE; BLOOD CLOTTING; CONTROLLED STUDY; DRUG SELECTIVITY; HUMAN; HUMAN CELL; NONHUMAN; PROTEIN DEGRADATION; RECEPTOR DOWN REGULATION; XENOPUS;

ANIMALS; CALCIUM; CELL LINE; HUMANS; OLIGOPEPTIDES; PEPTIDE FRAGMENTS; RECEPTOR, PAR-1; RECEPTOR, PAR-2; RECEPTORS, CELL SURFACE; RECEPTORS, THROMBIN; THROMBIN; TRYPSIN; XENOPUS;

EID: 0030667055     PISSN: 00838969     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (15)

1. Vu T-KH, Hung DT, Wheaton V.I. & Coughlin SR. Cell 64. 1057 (1991).
2. Rasmussen UG, Vouret-Craviari V, Jallat S, Schlesinger Y, Pages G, Pavirani A, Lecocq JP, Pouyssegur J & Van Obberghen-Schilling E. FEES Lett 288. 123 (1991).
3. Nystedt S, Emilsson K, Wahlestedt C & Sundelin J. Proc Nat Acad Sei USA 91. 9208 (1994).
4. Nystedt S, Larsson A-K, Aberg H & Sundelin J. J Biol Chem 270. 5950(1995).
5. Scarborough RM, Naughton MA, Teng W, Hung DT, Rose J, Vu T-KH, Wheaton V.I., Turek CW & Coughlin SR. J Biol Chem 267. 13146(1992).
6. Vassallo RR Jr, Kieber-Emmons T, Cichowski K & Brass IF. J Biol Chem 267. 6081 (1992).
7. Blackhart BD, Teng W, Naughton MA, Nystedt S, Emilsson K, Sundelin J & Scarborough RM. Thrombosis and Haemostasis 73. 928(1995).
8. Hollenberg MD, Laniyonu AA, Saifeddine M & Moore GJ. Mol Pharmacol43.921 (1993).
9. Natarajan S, Riexinger D, Peluse M & Seiler SM. Int. J Peptide Protein Res 45. 145(1995).
10. Tay-Uyboco J, Poon M-C, Ahmad S & Hollenberg MD. Br J Pharmacol 115.569(1995).
11. Blackhart BD, Emilsson K, Nguyen D, Teng W, Martelli AJ, Nystedt S, Sundelin J & Scarborough M. J Biol Chem 271. 16466 (1996).
12. Lum H, Anderdon TT, Siflinger-Birnboim A, Tiruppathi C, Goligorsku MS, Fenton JW II & Malik AB. J Cell Biol 120. 1491 (1993).
13. Zimmerman BJ, Paulson JC, Arrhenius TS, Gaeta FCA & Granger DN. Amer J Physio! 267. H1049 (1994).
14. Magazine HI, Butt O & Yaghoutiel HR. Amer Physiol 270. C1815(1994).
15. Laniyonu AA & Hollenberg MD. Br J Pharmacol 114. 1680 (1995).