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Volumn 24, Issue 1, 2005, Pages 165-183

Erratum: The role of B-RAF in melanoma (Cancer and Metastasis Reviews (January 2005) 24:1 DOI: http://dx.doi.org/10.1007/s10555-005-5865-1);The role of B-RAF in melanoma

Author keywords

B RAF; C RAF; ERK signalling; Melanocytes; Melanoma

Indexed keywords

B RAF KINASE; ISOPROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MUTANT PROTEIN; RAF PROTEIN; SORAFENIB;

EID: 17744388986     PISSN: 01677659     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10555-005-1585-9     Document Type: Erratum
Times cited : (136)

References (158)
  • 1
    • 0042021703 scopus 로고    scopus 로고
    • Ocular melanoma: A review and the relationship to cutaneous melanoma
    • Hurst EA, Harbour JW, Cornelius LA: Ocular melanoma: A review and the relationship to cutaneous melanoma. Arch Dermatol 139: 1067-1073, 2003
    • (2003) Arch Dermatol , vol.139 , pp. 1067-1073
    • Hurst, E.A.1    Harbour, J.W.2    Cornelius, L.A.3
  • 2
    • 0038578681 scopus 로고    scopus 로고
    • Acquired melanocytic nevi as risk factor for melanoma development. A comprehensive review of epidemiological data
    • Bauer J, Garbe C: Acquired melanocytic nevi as risk factor for melanoma development. A comprehensive review of epidemiological data. Pigment Cell Res 16: 297-306, 2003
    • (2003) Pigment Cell Res , vol.16 , pp. 297-306
    • Bauer, J.1    Garbe, C.2
  • 3
    • 0029153708 scopus 로고
    • Risk of cutaneous melanoma associated with pigmentation characteristics and freckling: Systematic overview of 10 case-control studies
    • The International Melanoma Analysis Group (IMAGE)
    • Bliss JM, Ford D, Swerdlow AJ, Armstrong BK, Cristofolini M, Elwood JM, Green A, Holly EA, Mack T, MacKie RM, et al.: Risk of cutaneous melanoma associated with pigmentation characteristics and freckling: Systematic overview of 10 case-control studies. The International Melanoma Analysis Group (IMAGE). Int J Cancer 62: 367-376, 1995.
    • (1995) Int J Cancer , vol.62 , pp. 367-376
    • Bliss, J.M.1    Ford, D.2    Swerdlow, A.J.3    Armstrong, B.K.4    Cristofolini, M.5    Elwood, J.M.6    Green, A.7    Holly, E.A.8    Mack, T.9    MacKie, R.M.10
  • 5
    • 1542611579 scopus 로고    scopus 로고
    • Global perspectives of contemporary epidemiological trends of cutaneous malignant melanoma
    • Lens MB, Dawes M: Global perspectives of contemporary epidemiological trends of cutaneous malignant melanoma. Br J Dermatol 150: 179-185, 2004
    • (2004) Br J Dermatol , vol.150 , pp. 179-185
    • Lens, M.B.1    Dawes, M.2
  • 6
    • 0036241593 scopus 로고    scopus 로고
    • The epidemiology of skin cancer
    • Diepgen TL, Mahler V: The epidemiology of skin cancer. Br J Dermatol 146(Suppl 61): 1-6, 2002
    • (2002) Br J Dermatol , vol.146 , Issue.61 SUPPL. , pp. 1-6
    • Diepgen, T.L.1    Mahler, V.2
  • 7
    • 0021743724 scopus 로고
    • A study of tumor progression: The precursor lesions of superficial spreading and nodular melanoma
    • Clark WH, Jr., Elder DE, Guerry DT, Epstein MN, Greene MH, Van Horn M: A study of tumor progression: The precursor lesions of superficial spreading and nodular melanoma. Hum Pathol 15: 1147-1165, 1984
    • (1984) Hum Pathol , vol.15 , pp. 1147-1165
    • Clark Jr., W.H.1    Elder, D.E.2    Guerry, D.T.3    Epstein, M.N.4    Greene, M.H.5    Van Horn, M.6
  • 9
    • 0025909122 scopus 로고
    • Tumour progression and the nature of cancer
    • Clark WH: Tumour progression and the nature of cancer. Br J Cancer 64: 631-644, 1991
    • (1991) Br J Cancer , vol.64 , pp. 631-644
    • Clark, W.H.1
  • 11
    • 0025820745 scopus 로고
    • Cutaneous melanoma
    • Koh HK: Cutaneous melanoma. N Engl J Med 325: 171-182, 1991
    • (1991) N Engl J Med , vol.325 , pp. 171-182
    • Koh, H.K.1
  • 12
    • 0030749315 scopus 로고    scopus 로고
    • The dysplastic naevus
    • Mooi WJ: The dysplastic naevus. J Clin Pathol 50: 711-715, 1997
    • (1997) J Clin Pathol , vol.50 , pp. 711-715
    • Mooi, W.J.1
  • 13
    • 0038456210 scopus 로고    scopus 로고
    • Death receptors and melanoma resistance to apoptosis
    • Ivanov VN, Bhoumik A, Ronai Z: Death receptors and melanoma resistance to apoptosis. Oncogene 22: 3152-3161, 2003
    • (2003) Oncogene , vol.22 , pp. 3152-3161
    • Ivanov, V.N.1    Bhoumik, A.2    Ronai, Z.3
  • 15
    • 0033614447 scopus 로고    scopus 로고
    • The pathogenesis of melanoma induced by ultraviolet radiation
    • Gilchrest BA, Eller MS, Geller AC, Yaar M: The pathogenesis of melanoma induced by ultraviolet radiation. N Engl J Med 340: 1341-1348, 1999
    • (1999) N Engl J Med , vol.340 , pp. 1341-1348
    • Gilchrest, B.A.1    Eller, M.S.2    Geller, A.C.3    Yaar, M.4
  • 17
    • 0025573042 scopus 로고
    • Malignant melanoma in England: Risks associated with naevi, freckles, social class, hair colour, and sunburn
    • Elwood JM, Whitehead SM, Davison J, Stewart M, Galt M: Malignant melanoma in England: Risks associated with naevi, freckles, social class, hair colour, and sunburn. Int J Epidemiol 19: 801-810, 1990
    • (1990) Int J Epidemiol , vol.19 , pp. 801-810
    • Elwood, J.M.1    Whitehead, S.M.2    Davison, J.3    Stewart, M.4    Galt, M.5
  • 19
    • 0029855237 scopus 로고    scopus 로고
    • Control of the ERK MAP kinase cascade by Ras and Raf
    • Marais R, Marshall CJ: Control of the ERK MAP kinase cascade by Ras and Raf. Cancer Surv 27: 101-125, 1996
    • (1996) Cancer Surv , vol.27 , pp. 101-125
    • Marais, R.1    Marshall, C.J.2
  • 20
    • 0030898417 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase pathways
    • Robinson MJ, Cobb MH: Mitogen-activated protein kinase pathways. Curr Opin Cell Biol 9: 180-186, 1997
    • (1997) Curr Opin Cell Biol , vol.9 , pp. 180-186
    • Robinson, M.J.1    Cobb, M.H.2
  • 21
    • 0035865137 scopus 로고    scopus 로고
    • Cross-talk between Ras and Rho signalling pathways in transformation favours proliferation and increased motility
    • Sahai E, Olson MF, Marshall CJ: Cross-talk between Ras and Rho signalling pathways in transformation favours proliferation and increased motility. Embo J 20: 755-766, 2001
    • (2001) Embo J , vol.20 , pp. 755-766
    • Sahai, E.1    Olson, M.F.2    Marshall, C.J.3
  • 22
    • 0038112035 scopus 로고    scopus 로고
    • Phosphorylation of p90 ribosomal S6 kinase (RSK) regulates extracellular signal-regulated kinase docking and RSK activity
    • Roux PP, Richards SA, Blenis J: Phosphorylation of p90 ribosomal S6 kinase (RSK) regulates extracellular signal-regulated kinase docking and RSK activity. Mol Cell Biol 23: 4796-4804, 2003
    • (2003) Mol Cell Biol , vol.23 , pp. 4796-4804
    • Roux, P.P.1    Richards, S.A.2    Blenis, J.3
  • 23
    • 0030977269 scopus 로고    scopus 로고
    • Mitogen-activated protein kinases activate the serine/threonine kinases Mnk1 and Mnk2
    • Waskiewicz AJ, Flynn A, Proud CG, Cooper JA: Mitogen-activated protein kinases activate the serine/threonine kinases Mnk1 and Mnk2. Embo J 16: 1909-1920, 1997
    • (1997) Embo J , vol.16 , pp. 1909-1920
    • Waskiewicz, A.J.1    Flynn, A.2    Proud, C.G.3    Cooper, J.A.4
  • 24
    • 0028872649 scopus 로고
    • Specificity of receptor tyrosine kinase signaling: Transient versus sustained extracellular signal-regulated kinase activation
    • Marshall CJ: Specificity of receptor tyrosine kinase signaling: Transient versus sustained extracellular signal-regulated kinase activation. Cell 80: 179-185, 1995
    • (1995) Cell , vol.80 , pp. 179-185
    • Marshall, C.J.1
  • 25
    • 0032522816 scopus 로고    scopus 로고
    • High-intensity Raf signals convert mitotic cell cycling into cellular growth
    • Kerkhoff E, Rapp UR: High-intensity Raf signals convert mitotic cell cycling into cellular growth. Cancer Res 58: 1636-1640, 1998
    • (1998) Cancer Res , vol.58 , pp. 1636-1640
    • Kerkhoff, E.1    Rapp, U.R.2
  • 26
    • 0024026804 scopus 로고
    • Ras-mediated cell cycle arrest is altered by nuclear oncogenes to induce Schwann cell transformation
    • Ridley AJ, Paterson HF, Noble M, Land H: Ras-mediated cell cycle arrest is altered by nuclear oncogenes to induce Schwann cell transformation. Embo J 7: 1635-1645, 1988
    • (1988) Embo J , vol.7 , pp. 1635-1645
    • Ridley, A.J.1    Paterson, H.F.2    Noble, M.3    Land, H.4
  • 27
    • 0030835430 scopus 로고    scopus 로고
    • Raf-induced proliferation or cell cycle arrest is determined by the level of Raf activity with arrest mediated by p21Cip1
    • Woods D, Parry D, Cherwinski H, Bosch E, Lees E, McMahon M: Raf-induced proliferation or cell cycle arrest is determined by the level of Raf activity with arrest mediated by p21Cip1. Mol Cell Biol 17: 5598-5611, 1997
    • (1997) Mol Cell Biol , vol.17 , pp. 5598-5611
    • Woods, D.1    Parry, D.2    Cherwinski, H.3    Bosch, E.4    Lees, E.5    McMahon, M.6
  • 28
    • 0032190629 scopus 로고    scopus 로고
    • Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling
    • Lin AW, Barradas M, Stone JC, van Aelst L, Serrano M, Lowe SW: Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling. Genes Dev 12: 3008-3019, 1998
    • (1998) Genes Dev , vol.12 , pp. 3008-3019
    • Lin, A.W.1    Barradas, M.2    Stone, J.C.3    Van Aelst, L.4    Serrano, M.5    Lowe, S.W.6
  • 29
    • 0030944985 scopus 로고    scopus 로고
    • Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a
    • Serrano M, Lin AW, McCurrach ME, Beach D, Lowe SW: Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a. Cell 88: 593-602, 1997
    • (1997) Cell , vol.88 , pp. 593-602
    • Serrano, M.1    Lin, A.W.2    McCurrach, M.E.3    Beach, D.4    Lowe, S.W.5
  • 30
    • 0031041171 scopus 로고    scopus 로고
    • Differential regulation of Raf-1, A-Raf, and B-Raf by oncogenic ras and tyrosine kinases
    • Marais R, Light Y, Paterson HF, Mason CS, Marshall CJ: Differential regulation of Raf-1, A-Raf, and B-Raf by oncogenic ras and tyrosine kinases. J Biol Chem 272: 4378-4383, 1997
    • (1997) J Biol Chem , vol.272 , pp. 4378-4383
    • Marais, R.1    Light, Y.2    Paterson, H.F.3    Mason, C.S.4    Marshall, C.J.5
  • 31
    • 0033604576 scopus 로고    scopus 로고
    • Isotype-specific functions of Raf kinases
    • Hagemann C, Rapp UR: Isotype-specific functions of Raf kinases. Exp Cell Res 253: 34-46, 1999
    • (1999) Exp Cell Res , vol.253 , pp. 34-46
    • Hagemann, C.1    Rapp, U.R.2
  • 32
    • 0028809479 scopus 로고
    • The mouse B-raf gene encodes multiple protein isoforms with tissue-specific expression
    • Barnier JV, Papin C, Eychene A, Lecoq O, Calothy G: The mouse B-raf gene encodes multiple protein isoforms with tissue-specific expression. J Biol Chem 270: 23381-23389, 1995
    • (1995) J Biol Chem , vol.270 , pp. 23381-23389
    • Barnier, J.V.1    Papin, C.2    Eychene, A.3    Lecoq, O.4    Calothy, G.5
  • 33
  • 34
    • 0038697566 scopus 로고    scopus 로고
    • Raf proteins and cancer: B-Raf is identified as a mutational target
    • Mercer KE, Pritchard CA: Raf proteins and cancer: B-Raf is identified as a mutational target. Biochim Biophys Acta 1653: 25-40, 2003
    • (2003) Biochim Biophys Acta , vol.1653 , pp. 25-40
    • Mercer, K.E.1    Pritchard, C.A.2
  • 35
    • 0028175091 scopus 로고
    • Raf meets Ras: Completing the framework of a signal transduction pathway
    • Avruch J, Zhang XF, Kyriakis JM: Raf meets Ras: Completing the framework of a signal transduction pathway. Trends Biochem Sci 19: 279-283, 1994
    • (1994) Trends Biochem Sci , vol.19 , pp. 279-283
    • Avruch, J.1    Zhang, X.F.2    Kyriakis, J.M.3
  • 36
    • 0036236897 scopus 로고    scopus 로고
    • Cyclic AMP-dependent kinase regulates Raf-1 kinase mainly by phosphorylation of serine 259
    • Dhillon AS, Pollock C, Steen H, Shaw PE, Mischak H, Kolch W: Cyclic AMP-dependent kinase regulates Raf-1 kinase mainly by phosphorylation of serine 259. Mol Cell Biol 22: 3237-3246, 2002
    • (2002) Mol Cell Biol , vol.22 , pp. 3237-3246
    • Dhillon, A.S.1    Pollock, C.2    Steen, H.3    Shaw, P.E.4    Mischak, H.5    Kolch, W.6
  • 37
    • 0036297889 scopus 로고    scopus 로고
    • 14-3-3 antagonizes Ras-mediated Raf-1 recruitment to the plasma membrane to maintain signaling fidelity
    • Light Y, Paterson H, Marais R: 14-3-3 antagonizes Ras-mediated Raf-1 recruitment to the plasma membrane to maintain signaling fidelity. Mol Cell Biol 22: 4984-4996, 2002
    • (2002) Mol Cell Biol , vol.22 , pp. 4984-4996
    • Light, Y.1    Paterson, H.2    Marais, R.3
  • 39
    • 0035811597 scopus 로고    scopus 로고
    • Protein phosphatases 1 and 2A promote Raf-1 activation by regulating 14-3-3 interactions
    • Jaumot M, Hancock JF: Protein phosphatases 1 and 2A promote Raf-1 activation by regulating 14-3-3 interactions. Oncogene 20: 3949-3958, 2001
    • (2001) Oncogene , vol.20 , pp. 3949-3958
    • Jaumot, M.1    Hancock, J.F.2
  • 40
    • 0042178312 scopus 로고    scopus 로고
    • Protein phosphatase 2A positively regulates Ras signaling by dephosphorylating KSR1 and Raf-1 on critical 14-3-3 binding sites
    • Ory S, Zhou M, Conrads TP, Veenstra TD, Morrison DK: Protein phosphatase 2A positively regulates Ras signaling by dephosphorylating KSR1 and Raf-1 on critical 14-3-3 binding sites. Curr Biol 13: 1356-1364, 2003
    • (2003) Curr Biol , vol.13 , pp. 1356-1364
    • Ory, S.1    Zhou, M.2    Conrads, T.P.3    Veenstra, T.D.4    Morrison, D.K.5
  • 41
    • 0034675919 scopus 로고    scopus 로고
    • Activation of B-Raf kinase requires phosphorylation of the conserved residues Thr598 and Ser601
    • Zhang BH, Guan KL: Activation of B-Raf kinase requires phosphorylation of the conserved residues Thr598 and Ser601. Embo J 19: 5429-5439, 2000
    • (2000) Embo J , vol.19 , pp. 5429-5439
    • Zhang, B.H.1    Guan, K.L.2
  • 43
    • 5444227865 scopus 로고    scopus 로고
    • Guilty as charged; B-RAF is a human oncogene
    • Garnett MJ, Marais R: Guilty as charged; B-RAF is a human oncogene. Cancer Cell 6: 313-319, 2004
    • (2004) Cancer Cell , vol.6 , pp. 313-319
    • Garnett, M.J.1    Marais, R.2
  • 44
    • 0035898539 scopus 로고    scopus 로고
    • Positive and negative regulation of Raf kinase activity and function by phosphorylation
    • Chong H, Lee J, Guan KL: Positive and negative regulation of Raf kinase activity and function by phosphorylation. Embo J 20: 3716-3727, 2001
    • (2001) Embo J , vol.20 , pp. 3716-3727
    • Chong, H.1    Lee, J.2    Guan, K.L.3
  • 45
    • 0032511882 scopus 로고    scopus 로고
    • The protein kinase Pak3 positively regulates Raf-1 activity through phosphorylation of serine 338
    • King AJ, Sun H, Diaz B, Barnard D, Miao W, Bagrodia S, Marshall MS: The protein kinase Pak3 positively regulates Raf-1 activity through phosphorylation of serine 338. Nature 396: 180-183, 1998
    • (1998) Nature , vol.396 , pp. 180-183
    • King, A.J.1    Sun, H.2    Diaz, B.3    Barnard, D.4    Miao, W.5    Bagrodia, S.6    Marshall, M.S.7
  • 46
    • 0027364980 scopus 로고
    • Critical tyrosine residues regulate the enzymatic and biological activity of Raf-1 kinase
    • Fabian JR, Daar IO, Morrison DK: Critical tyrosine residues regulate the enzymatic and biological activity of Raf-1 kinase. Mol Cell Biol 13: 7170-7179, 1993
    • (1993) Mol Cell Biol , vol.13 , pp. 7170-7179
    • Fabian, J.R.1    Daar, I.O.2    Morrison, D.K.3
  • 48
    • 0035907051 scopus 로고    scopus 로고
    • Phosphorylation site specificity of the Pak-mediated regulation of Raf-1 and cooperativity with Src
    • King AJ, Wireman RS, Hamilton M, Marshall MS: Phosphorylation site specificity of the Pak-mediated regulation of Raf-1 and cooperativity with Src. FEBS Lett 497: 6-14, 2001
    • (2001) FEBS Lett , vol.497 , pp. 6-14
    • King, A.J.1    Wireman, R.S.2    Hamilton, M.3    Marshall, M.S.4
  • 49
    • 0037400975 scopus 로고    scopus 로고
    • A pivotal role for ERK in the oncogenic behaviour of malignant melanoma?
    • Smalley KS: A pivotal role for ERK in the oncogenic behaviour of malignant melanoma? Int J Cancer 104: 527-532, 2003
    • (2003) Int J Cancer , vol.104 , pp. 527-532
    • Smalley, K.S.1
  • 50
    • 0037442752 scopus 로고    scopus 로고
    • Constitutive mitogen-activated protein kinase activation in melanoma is mediated by both BRAF mutations and autocrine growth factor stimulation
    • Satyamoorthy K, Li G, Gerrero MR, Brose MS, Volpe P, Weber BL, Van Belle P, Elder DE, Herlyn M: Constitutive mitogen-activated protein kinase activation in melanoma is mediated by both BRAF mutations and autocrine growth factor stimulation. Cancer Res 63: 756-759, 2003
    • (2003) Cancer Res , vol.63 , pp. 756-759
    • Satyamoorthy, K.1    Li, G.2    Gerrero, M.R.3    Brose, M.S.4    Volpe, P.5    Weber, B.L.6    Van Belle, P.7    Elder, D.E.8    Herlyn, M.9
  • 55
    • 2942607408 scopus 로고    scopus 로고
    • Constitutive activation of the Ras-Raf signaling pathway in metastatic melanoma is associated with poor prognosis
    • Houben R, Becker JC, Kappel A, Terheyden P, Brocker EB, Goetz R, Rapp UR: Constitutive activation of the Ras-Raf signaling pathway in metastatic melanoma is associated with poor prognosis. J Carcinog 3: 6, 2004
    • (2004) J Carcinog , vol.3 , pp. 6
    • Houben, R.1    Becker, J.C.2    Kappel, A.3    Terheyden, P.4    Brocker, E.B.5    Goetz, R.6    Rapp, U.R.7
  • 57
    • 1442269853 scopus 로고    scopus 로고
    • Activating BRAF and N-Ras mutations in sporadic primary melanomas: An inverse association with allelic loss on chromosome 9
    • Kumar R, Angelini S, Hemminki K: Activating BRAF and N-Ras mutations in sporadic primary melanomas: An inverse association with allelic loss on chromosome 9. Oncogene 22: 9217-9224, 2003
    • (2003) Oncogene , vol.22 , pp. 9217-9224
    • Kumar, R.1    Angelini, S.2    Hemminki, K.3
  • 61
    • 1442323605 scopus 로고    scopus 로고
    • BRAF mutations are common somatic events in melanocytic nevi
    • Kumar R, Angelini S, Snellman E, Hemminki K: BRAF mutations are common somatic events in melanocytic nevi. J Invest Dermatol 122: 342-348, 2004
    • (2004) J Invest Dermatol , vol.122 , pp. 342-348
    • Kumar, R.1    Angelini, S.2    Snellman, E.3    Hemminki, K.4
  • 64
    • 0032767677 scopus 로고    scopus 로고
    • Mutational analysis of the N-ras, p53, p16INK4a, CDK4, and MC1R genes in human congenital melanocytic naevi
    • Papp T, Pemsel H, Zimmermann R, Bastrop R, Weiss DG, Schiffmann D: Mutational analysis of the N-ras, p53, p16INK4a, CDK4, and MC1R genes in human congenital melanocytic naevi. J Med Genet 36: 610-614, 1999
    • (1999) J Med Genet , vol.36 , pp. 610-614
    • Papp, T.1    Pemsel, H.2    Zimmermann, R.3    Bastrop, R.4    Weiss, D.G.5    Schiffmann, D.6
  • 65
    • 0042743826 scopus 로고    scopus 로고
    • BRAF oncogenic mutations correlate with progression rather than initiation of human melanoma
    • Dong J, Phelps RG, Qiao R, Yao S, Benard O, Ronai Z, Aaronson SA: BRAF oncogenic mutations correlate with progression rather than initiation of human melanoma. Cancer Res 63: 3883-3885, 2003
    • (2003) Cancer Res , vol.63 , pp. 3883-3885
    • Dong, J.1    Phelps, R.G.2    Qiao, R.3    Yao, S.4    Benard, O.5    Ronai, Z.6    Aaronson, S.A.7
  • 67
    • 1842428668 scopus 로고    scopus 로고
    • Incidence of BRAF oncogene mutation and clinical relevance for primary cutaneous melanomas
    • Shinozaki M, Fujimoto A, Morton DL, Hoon DS: Incidence of BRAF oncogene mutation and clinical relevance for primary cutaneous melanomas. Clin Cancer Res 10: 1753-1757, 2004
    • (2004) Clin Cancer Res , vol.10 , pp. 1753-1757
    • Shinozaki, M.1    Fujimoto, A.2    Morton, D.L.3    Hoon, D.S.4
  • 68
    • 0348223934 scopus 로고    scopus 로고
    • NRAS and BRAF mutations arise early during melanoma pathogenesis and are preserved throughout tumor progression
    • Omholt K, Platz A, Kanter L, Ringborg U, Hansson J: NRAS and BRAF mutations arise early during melanoma pathogenesis and are preserved throughout tumor progression. Clin Cancer Res 9: 6483-6488, 2003
    • (2003) Clin Cancer Res , vol.9 , pp. 6483-6488
    • Omholt, K.1    Platz, A.2    Kanter, L.3    Ringborg, U.4    Hansson, J.5
  • 70
    • 0037222652 scopus 로고    scopus 로고
    • Absence of exon 15 BRAF germline mutations in familial melanoma
    • Lang J, Boxer M, MacKie R: Absence of exon 15 BRAF germline mutations in familial melanoma. Hum Mutat 21: 327-330, 2003
    • (2003) Hum Mutat , vol.21 , pp. 327-330
    • Lang, J.1    Boxer, M.2    MacKie, R.3
  • 73
    • 2942625415 scopus 로고    scopus 로고
    • Polymorphisms of the BRAF gene predispose males to malignant melanoma
    • Meyer P, Sergi C, Garbe C: Polymorphisms of the BRAF gene predispose males to malignant melanoma. J Carcinog 2: 7, 2003
    • (2003) J Carcinog , vol.2 , pp. 7
    • Meyer, P.1    Sergi, C.2    Garbe, C.3
  • 74
    • 0033997943 scopus 로고    scopus 로고
    • Overlapping and specific functions of Braf and Craf-1 proto-oncogenes during mouse embryogenesis
    • Wojnowski L, Stancato LF, Larner AC, Rapp UR, Zimmer A: Overlapping and specific functions of Braf and Craf-1 proto-oncogenes during mouse embryogenesis. Mech Dev 91: 97-104, 2000
    • (2000) Mech Dev , vol.91 , pp. 97-104
    • Wojnowski, L.1    Stancato, L.F.2    Larner, A.C.3    Rapp, U.R.4    Zimmer, A.5
  • 76
    • 0037779497 scopus 로고    scopus 로고
    • Ultraviolet radiation and cutaneous malignant melanoma
    • Jhappan C, Noonan FP, Merlino G: Ultraviolet radiation and cutaneous malignant melanoma. Oncogene 22: 3099-3112, 2003
    • (2003) Oncogene , vol.22 , pp. 3099-3112
    • Jhappan, C.1    Noonan, F.P.2    Merlino, G.3
  • 77
    • 0030447224 scopus 로고    scopus 로고
    • Melanoma and sun exposure
    • Elwood JM: Melanoma and sun exposure. Semin Oncol 23: 650-666, 1996
    • (1996) Semin Oncol , vol.23 , pp. 650-666
    • Elwood, J.M.1
  • 81
    • 0031738326 scopus 로고    scopus 로고
    • N-ras mutations are common in melanomas from sun-exposed skin of humans but rare in mucosal membranes or unexposed skin
    • Jiveskog S, Ragnarsson-Olding B, Platz A, Ringborg U: N-ras mutations are common in melanomas from sun-exposed skin of humans but rare in mucosal membranes or unexposed skin. J Invest Dermatol 111: 757-761, 1998
    • (1998) J Invest Dermatol , vol.111 , pp. 757-761
    • Jiveskog, S.1    Ragnarsson-Olding, B.2    Platz, A.3    Ringborg, U.4
  • 82
    • 0029199911 scopus 로고
    • Analysis of N-ras mutations in human cutaneous melanoma: Tumor heterogeneity detected by polymerase chain reaction/single-stranded conformation polymorphism analysis
    • van Elsas A, Zerp S, van der Flier S, Kruse-Wolters M, Vacca A, Ruiter DJ, Schrier P: Analysis of N-ras mutations in human cutaneous melanoma: Tumor heterogeneity detected by polymerase chain reaction/single-stranded conformation polymorphism analysis. Recent Results Cancer Res 139: 57-67, 1995
    • (1995) Recent Results Cancer Res , vol.139 , pp. 57-67
    • Van Elsas, A.1    Zerp, S.2    Van Der Flier, S.3    Kruse-Wolters, M.4    Vacca, A.5    Ruiter, D.J.6    Schrier, P.7
  • 83
    • 0027379357 scopus 로고
    • Specific UV-induced mutation spectrum in the p53 gene of skin tumors from DNA-repair-deficient xeroderma pigmentosum patients
    • Dumaz N, Drougard C, Sarasin A, Daya-Grosjean L: Specific UV-induced mutation spectrum in the p53 gene of skin tumors from DNA-repair-deficient xeroderma pigmentosum patients. Proc Natl Acad Sci USA 90: 10529-10533, 1993
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 10529-10533
    • Dumaz, N.1    Drougard, C.2    Sarasin, A.3    Daya-Grosjean, L.4
  • 85
    • 0023147412 scopus 로고
    • Involvement of reactive oxygen species in the oxidation of tyrosine and dopa to melanin and in skin tanning
    • Joshi PC, Carraro C, Pathak MA: Involvement of reactive oxygen species in the oxidation of tyrosine and dopa to melanin and in skin tanning. Biochem Biophys Res Commun 142: 265-274, 1987
    • (1987) Biochem Biophys Res Commun , vol.142 , pp. 265-274
    • Joshi, P.C.1    Carraro, C.2    Pathak, M.A.3
  • 86
    • 0038457477 scopus 로고    scopus 로고
    • Human melanocyte senescence and melanoma susceptibility genes
    • Bennett DC: Human melanocyte senescence and melanoma susceptibility genes. Oncogene 22: 3063-3069, 2003
    • (2003) Oncogene , vol.22 , pp. 3063-3069
    • Bennett, D.C.1
  • 87
    • 0001510491 scopus 로고    scopus 로고
    • The RB and p53 pathways in cancer
    • Sherr CJ, McCormick F: The RB and p53 pathways in cancer. Cancer Cell 2: 103-112, 2002
    • (2002) Cancer Cell , vol.2 , pp. 103-112
    • Sherr, C.J.1    McCormick, F.2
  • 91
    • 0038456399 scopus 로고    scopus 로고
    • PTEN signaling pathways in melanoma
    • Wu H, Goel V, Haluska F G: PTEN signaling pathways in melanoma. Oncogene 22: 3113-3122, 2003
    • (2003) Oncogene , vol.22 , pp. 3113-3122
    • Wu, H.1    Goel, V.2    Haluska, F.G.3
  • 92
    • 0037115394 scopus 로고    scopus 로고
    • Constitutive activation of Akt/protein kinase B in melanoma leads to up-regulation of nuclear factor-kappaB and tumor progression
    • Dhawan P, Singh AB, Ellis DL, Richmond A: Constitutive activation of Akt/protein kinase B in melanoma leads to up-regulation of nuclear factor-kappaB and tumor progression. Cancer Res 62: 7335-7342, 2002
    • (2002) Cancer Res , vol.62 , pp. 7335-7342
    • Dhawan, P.1    Singh, A.B.2    Ellis, D.L.3    Richmond, A.4
  • 94
    • 0034085811 scopus 로고    scopus 로고
    • Relative reciprocity of NRAS and PTEN/MMAC1 alterations in cutaneous melanoma cell lines
    • Tsao H, Zhang X, Fowlkes K, Haluska FG: Relative reciprocity of NRAS and PTEN/MMAC1 alterations in cutaneous melanoma cell lines. Cancer Res 60: 1800-1804, 2000
    • (2000) Cancer Res , vol.60 , pp. 1800-1804
    • Tsao, H.1    Zhang, X.2    Fowlkes, K.3    Haluska, F.G.4
  • 95
    • 1442274619 scopus 로고    scopus 로고
    • Genetic interaction between NRAS and BRAF mutations and PTEN/MMAC1 inactivation in melanoma
    • Tsao H, Goel V, Wu H, Yang G, Haluska FG: Genetic interaction between NRAS and BRAF mutations and PTEN/MMAC1 inactivation in melanoma. J Invest Dermatol 122: 337-341, 2004
    • (2004) J Invest Dermatol , vol.122 , pp. 337-341
    • Tsao, H.1    Goel, V.2    Wu, H.3    Yang, G.4    Haluska, F.G.5
  • 96
    • 13944284494 scopus 로고    scopus 로고
    • Oncogenic Mutations of PIK3CA in Human Cancers
    • Samuels Y, Velculescu VE: Oncogenic Mutations of PIK3CA in Human Cancers. Cell Cycle 3: 2004
    • (2004) Cell Cycle , vol.3
    • Samuels, Y.1    Velculescu, V.E.2
  • 97
    • 0037864520 scopus 로고    scopus 로고
    • Tuberous sclerosis complex (TSC) gene involvement in sporadic tumours
    • Knowles MA, Hornigold N, Pitt E: Tuberous sclerosis complex (TSC) gene involvement in sporadic tumours. Biochem Soc Trans 31: 597-602, 2003
    • (2003) Biochem Soc Trans , vol.31 , pp. 597-602
    • Knowles, M.A.1    Hornigold, N.2    Pitt, E.3
  • 100
    • 2442660578 scopus 로고    scopus 로고
    • Different effects of point mutations within the B-Raf glycine-rich loop in colorectal tumors on mitogen-activated protein/extracellular signal-regulated kinase kinase/extracellular signal-regulated kinase and nuclear factor kappaB pathway and cellular transformation
    • Ikenoue T, Hikiba Y, Kanai F, Aragaki J, Tanaka Y, Imamura J, Imamura T, Ohta M, Ijichi H, Tateishi K, Kawakami T, Matsumura M, Kawabe T, Omata M: Different effects of point mutations within the B-Raf glycine-rich loop in colorectal tumors on mitogen-activated protein/extracellular signal-regulated kinase kinase/extracellular signal-regulated kinase and nuclear factor kappaB pathway and cellular transformation. Cancer Res 64: 3428-3435, 2004
    • (2004) Cancer Res , vol.64 , pp. 3428-3435
    • Ikenoue, T.1    Hikiba, Y.2    Kanai, F.3    Aragaki, J.4    Tanaka, Y.5    Imamura, J.6    Imamura, T.7    Ohta, M.8    Ijichi, H.9    Tateishi, K.10    Kawakami, T.11    Matsumura, M.12    Kawabe, T.13    Omata, M.14
  • 101
    • 0028306229 scopus 로고
    • Terminal differentiation and senescence in the human melanocyte: Repression of tyrosine-phosphorylation of the extracellular signal-regulated kinase 2 selectively defines the two phenotypes
    • Medrano EE, Yang F, Boissy R, Farooqui J, Shah V, Matsumoto K, Nordlund JJ, Park HY: Terminal differentiation and senescence in the human melanocyte: Repression of tyrosine-phosphorylation of the extracellular signal-regulated kinase 2 selectively defines the two phenotypes. Mol Biol Cell 5: 497-509, 1994
    • (1994) Mol Biol Cell , vol.5 , pp. 497-509
    • Medrano, E.E.1    Yang, F.2    Boissy, R.3    Farooqui, J.4    Shah, V.5    Matsumoto, K.6    Nordlund, J.J.7    Park, H.Y.8
  • 102
  • 103
    • 0041529686 scopus 로고    scopus 로고
    • Protein kinase a blocks Raf-1 activity by stimulating 14-3-3 binding and blocking Raf-1 interaction with Ras
    • Dumaz N, Marais R: Protein kinase A blocks Raf-1 activity by stimulating 14-3-3 binding and blocking Raf-1 interaction with Ras. J Biol Chem 278: 29819-29823, 2003
    • (2003) J Biol Chem , vol.278 , pp. 29819-29823
    • Dumaz, N.1    Marais, R.2
  • 104
    • 0034666006 scopus 로고    scopus 로고
    • Phosphorylation of serine 43 is not required for inhibition of c-Raf kinase by the cAMP-dependent protein kinase
    • Sidovar MF, Kozlowski P, Lee JW, Collins MA, He Y, Graves LM: Phosphorylation of serine 43 is not required for inhibition of c-Raf kinase by the cAMP-dependent protein kinase. J Biol Chem 275: 28688-28694, 2000
    • (2000) J Biol Chem , vol.275 , pp. 28688-28694
    • Sidovar, M.F.1    Kozlowski, P.2    Lee, J.W.3    Collins, M.A.4    He, Y.5    Graves, L.M.6
  • 105
    • 0027772672 scopus 로고
    • Inhibition of the EGF-activated MAP kinase signaling pathway by adenosine 3′,5′-monophosphate
    • Wu J, Dent P, Jelinek T, Wolfman A, Weber MJ, Sturgill TW: Inhibition of the EGF-activated MAP kinase signaling pathway by adenosine 3′,5′- monophosphate. Science 262: 1065-1069, 1993
    • (1993) Science , vol.262 , pp. 1065-1069
    • Wu, J.1    Dent, P.2    Jelinek, T.3    Wolfman, A.4    Weber, M.J.5    Sturgill, T.W.6
  • 107
    • 0032560489 scopus 로고    scopus 로고
    • The eleventh datta lecture. The structural basis for substrate recognition and control by protein kinases
    • Johnson LN, Lowe ED, Noble ME, Owen DJ: The eleventh datta lecture. The structural basis for substrate recognition and control by protein kinases. FEBS Lett 430: 1-11, 1998
    • (1998) FEBS Lett , vol.430 , pp. 1-11
    • Johnson, L.N.1    Lowe, E.D.2    Noble, M.E.3    Owen, D.J.4
  • 109
    • 0142211228 scopus 로고    scopus 로고
    • Mutation of B-Raf in human choroidal melanoma cells mediates cell proliferation and transformation through the MEK/ERK pathway
    • Calipel A, Lefevre G, Pouponnot C, Mouriaux F, Eychene A, Mascarelli F: Mutation of B-Raf in human choroidal melanoma cells mediates cell proliferation and transformation through the MEK/ERK pathway. J Biol Chem 278: 42409-42418, 2003
    • (2003) J Biol Chem , vol.278 , pp. 42409-42418
    • Calipel, A.1    Lefevre, G.2    Pouponnot, C.3    Mouriaux, F.4    Eychene, A.5    Mascarelli, F.6
  • 112
    • 4444240325 scopus 로고    scopus 로고
    • Inhibition of growth and invasive ability of melanoma by inactivation of mutated BRAF with lentivirus-mediated RNA interference
    • Sumimoto H, Miyagishi M, Miyoshi H, Yamagata S, Shimizu A, Taira K, Kawakami Y: Inhibition of growth and invasive ability of melanoma by inactivation of mutated BRAF with lentivirus-mediated RNA interference. Oncogene 23: 6031-6039, 2004
    • (2004) Oncogene , vol.23 , pp. 6031-6039
    • Sumimoto, H.1    Miyagishi, M.2    Miyoshi, H.3    Yamagata, S.4    Shimizu, A.5    Taira, K.6    Kawakami, Y.7
  • 113
    • 0023145290 scopus 로고
    • A line of non-tumorigenic mouse melanocytes, syngeneic with the B16 melanoma and requiring a tumour promoter for growth
    • Bennett DC, Cooper PJ, Hart IR: A line of non-tumorigenic mouse melanocytes, syngeneic with the B16 melanoma and requiring a tumour promoter for growth. Int J Cancer 39: 414-418, 1987
    • (1987) Int J Cancer , vol.39 , pp. 414-418
    • Bennett, D.C.1    Cooper, P.J.2    Hart, I.R.3
  • 115
    • 0028324596 scopus 로고
    • Expression of cytokine/growth factors and their receptors in human melanoma and melanocytes
    • Mattei S, Colombo MP, Melani C, Silvani A, Parmiani G, Herlyn M: Expression of cytokine/growth factors and their receptors in human melanoma and melanocytes. Int J Cancer 56: 853-857, 1994
    • (1994) Int J Cancer , vol.56 , pp. 853-857
    • Mattei, S.1    Colombo, M.P.2    Melani, C.3    Silvani, A.4    Parmiani, G.5    Herlyn, M.6
  • 116
    • 0342646934 scopus 로고    scopus 로고
    • Autocrine and paracrine regulation by cytokines and growth factors in melanoma
    • Lazar-Molnar E, Hegyesi H, Toth S, Falus A: Autocrine and paracrine regulation by cytokines and growth factors in melanoma. Cytokine 12: 547-554, 2000
    • (2000) Cytokine , vol.12 , pp. 547-554
    • Lazar-Molnar, E.1    Hegyesi, H.2    Toth, S.3    Falus, A.4
  • 119
    • 0033603018 scopus 로고    scopus 로고
    • MEK1 activation rescues Jurkat T cells from Fas-induced apoptosis
    • Wilson DJ, Alessandrini A, Budd RC: MEK1 activation rescues Jurkat T cells from Fas-induced apoptosis. Cell Immunol 194: 67-77, 1999
    • (1999) Cell Immunol , vol.194 , pp. 67-77
    • Wilson, D.J.1    Alessandrini, A.2    Budd, R.C.3
  • 120
    • 0032793067 scopus 로고    scopus 로고
    • B-Raf inhibits programmed cell death downstream of cytochrome c release from mitochondria by activating the MEK/Erk pathway
    • Erhardt P, Schremser EJ, Cooper GM: B-Raf inhibits programmed cell death downstream of cytochrome c release from mitochondria by activating the MEK/Erk pathway. Mol Cell Biol 19: 5308-5315, 1999
    • (1999) Mol Cell Biol , vol.19 , pp. 5308-5315
    • Erhardt, P.1    Schremser, E.J.2    Cooper, G.M.3
  • 121
    • 2942715013 scopus 로고    scopus 로고
    • B-Raf acts via the ROCKII/LIMK/cofilin pathway to maintain actin stress fibers in fibroblasts
    • Pritchard CA, Hayes L, Wojnowski L, Zimmer A, Marais RM, Norman JC: B-Raf acts via the ROCKII/LIMK/cofilin pathway to maintain actin stress fibers in fibroblasts. Mol Cell Biol 24: 5937-5952, 2004
    • (2004) Mol Cell Biol , vol.24 , pp. 5937-5952
    • Pritchard, C.A.1    Hayes, L.2    Wojnowski, L.3    Zimmer, A.4    Marais, R.M.5    Norman, J.C.6
  • 122
    • 0032404174 scopus 로고    scopus 로고
    • A single nucleotide polymorphism in the matrix metalloproteinase-1 promoter creates an Ets binding site and augments transcription
    • Rutter JL, Mitchell TI, Buttice G, Meyers J, Gusella JF, Ozelius LJ, Brinckerhoff CE: A single nucleotide polymorphism in the matrix metalloproteinase-1 promoter creates an Ets binding site and augments transcription. Cancer Res 58: 5321-5325, 1998
    • (1998) Cancer Res , vol.58 , pp. 5321-5325
    • Rutter, J.L.1    Mitchell, T.I.2    Buttice, G.3    Meyers, J.4    Gusella, J.F.5    Ozelius, L.J.6    Brinckerhoff, C.E.7
  • 124
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan D, Weinberg RA: The hallmarks of cancer. Cell 100: 57-70, 2000
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 127
    • 4644259265 scopus 로고    scopus 로고
    • Kinase inhibition with BAY 43-9006 in renal cell carcinoma
    • Ahmad T, Eisen T: Kinase inhibition with BAY 43-9006 in renal cell carcinoma. Clin Cancer Res 10: 6388S-6392S, 2004
    • (2004) Clin Cancer Res , vol.10
    • Ahmad, T.1    Eisen, T.2
  • 128
    • 1642569629 scopus 로고    scopus 로고
    • New molecular targets in melanoma
    • Flaherty KT: New molecular targets in melanoma. Curr Opin Oncol 16: 150-154, 2004
    • (2004) Curr Opin Oncol , vol.16 , pp. 150-154
    • Flaherty, K.T.1
  • 129
    • 0035393498 scopus 로고    scopus 로고
    • Pharmacological inhibitors of the mitogen-activated protein kinase (MAPK) kinase/MAPK cascade interact synergistically with UCN-01 to induce mitochondrial dysfunction and apoptosis in human leukemia cells
    • Dai Y, Yu C, Singh V, Tang L, Wang Z, McInistry R, Dent P, Grant S: Pharmacological inhibitors of the mitogen-activated protein kinase (MAPK) kinase/MAPK cascade interact synergistically with UCN-01 to induce mitochondrial dysfunction and apoptosis in human leukemia cells. Cancer Res 61: 5106-5115, 2001
    • (2001) Cancer Res , vol.61 , pp. 5106-5115
    • Dai, Y.1    Yu, C.2    Singh, V.3    Tang, L.4    Wang, Z.5    McInistry, R.6    Dent, P.7    Grant, S.8
  • 130
    • 4143139997 scopus 로고    scopus 로고
    • SPRY2 is an inhibitor of the ras/extracellular signal-regulated kinase pathway in melanocytes and melanoma cells with wild-type BRAF but not with the V599E mutant
    • Tsavachidou D, Coleman ML, Athanasiadis G, Li S, Licht JD, Olson MF, Weber BL: SPRY2 is an inhibitor of the ras/extracellular signal-regulated kinase pathway in melanocytes and melanoma cells with wild-type BRAF but not with the V599E mutant. Cancer Res 64: 5556-5559, 2004
    • (2004) Cancer Res , vol.64 , pp. 5556-5559
    • Tsavachidou, D.1    Coleman, M.L.2    Athanasiadis, G.3    Li, S.4    Licht, J.D.5    Olson, M.F.6    Weber, B.L.7
  • 133
    • 0032517341 scopus 로고    scopus 로고
    • The p16INK4a/CDKN2A tumor suppressor and its relatives
    • Ruas M, Peters G: The p16INK4a/CDKN2A tumor suppressor and its relatives. Biochim Biophys Acta 1378: F115-177, 1998
    • (1998) Biochim Biophys Acta , vol.1378
    • Ruas, M.1    Peters, G.2
  • 134
    • 0030467624 scopus 로고    scopus 로고
    • The p16-cyclin D/Cdk4-pRb pathway as a functional unit frequently altered in melanoma pathogenesis
    • Bartkova J, Lukas J, Guldberg P, Alsner J, Kirkin AF, Zeuthen J, Bartek J: The p16-cyclin D/Cdk4-pRb pathway as a functional unit frequently altered in melanoma pathogenesis. Cancer Res 56: 5475-5483, 1996
    • (1996) Cancer Res , vol.56 , pp. 5475-5483
    • Bartkova, J.1    Lukas, J.2    Guldberg, P.3    Alsner, J.4    Kirkin, A.F.5    Zeuthen, J.6    Bartek, J.7
  • 136
    • 0035881619 scopus 로고    scopus 로고
    • The transcriptional repressor of p16/Ink4a, Id1, is up-regulated in early melanomas
    • Polsky D, Young AZ, Busam KJ, Alani RM: The transcriptional repressor of p16/Ink4a, Id1, is up-regulated in early melanomas. Cancer Res 61: 6008-6011, 2001
    • (2001) Cancer Res , vol.61 , pp. 6008-6011
    • Polsky, D.1    Young, A.Z.2    Busam, K.J.3    Alani, R.M.4
  • 137
    • 0034103810 scopus 로고    scopus 로고
    • Loss of nuclear p16 protein expression correlates with increased tumor cell proliferation (Ki-67) and poor prognosis in patients with vertical growth phase melanoma
    • Straume O, Sviland L, Akslen LA: Loss of nuclear p16 protein expression correlates with increased tumor cell proliferation (Ki-67) and poor prognosis in patients with vertical growth phase melanoma. Clin Cancer Res 6: 1845-1853, 2000
    • (2000) Clin Cancer Res , vol.6 , pp. 1845-1853
    • Straume, O.1    Sviland, L.2    Akslen, L.A.3
  • 138
    • 0030659080 scopus 로고    scopus 로고
    • Alterations and prognostic significance of p16 and p53 protein expression in subgroups of cutaneous melanoma
    • Straume O, Akslen LA: Alterations and prognostic significance of p16 and p53 protein expression in subgroups of cutaneous melanoma. Int J Cancer 74: 535-539, 1997
    • (1997) Int J Cancer , vol.74 , pp. 535-539
    • Straume, O.1    Akslen, L.A.2
  • 144
    • 0142029990 scopus 로고    scopus 로고
    • The role of Bcl-2 family members in the progression of cutaneous melanoma
    • Bush JA, Li G: The role of Bcl-2 family members in the progression of cutaneous melanoma. Clin Exp Metastasis 20: 531-539, 2003
    • (2003) Clin Exp Metastasis , vol.20 , pp. 531-539
    • Bush, J.A.1    Li, G.2
  • 145
    • 0035094177 scopus 로고    scopus 로고
    • Gene regulation in melanoma progression by the AP-2 transcription factor
    • Bar-Eli M: Gene regulation in melanoma progression by the AP-2 transcription factor. Pigment Cell Res 14: 78-85, 2001
    • (2001) Pigment Cell Res , vol.14 , pp. 78-85
    • Bar-Eli, M.1
  • 146
    • 0030777104 scopus 로고    scopus 로고
    • Disruption of the MMAC1/PTEN gene by deletion or mutation is a frequent event in malignant melanoma
    • Guldberg P, thor Straten P, Birck A, Ahrenkiel V, Kirkin AF, Zeuthen J: Disruption of the MMAC1/PTEN gene by deletion or mutation is a frequent event in malignant melanoma. Cancer Res 57: 3660-3663, 1997
    • (1997) Cancer Res , vol.57 , pp. 3660-3663
    • Guldberg, P.1    Thor Straten, P.2    Birck, A.3    Ahrenkiel, V.4    Kirkin, A.F.5    Zeuthen, J.6
  • 148
    • 0035877115 scopus 로고    scopus 로고
    • Cytoplasmic and nuclear accumulation of beta-catenin is rarely caused by CTNNB1 exon 3 mutations in cutaneous malignant melanoma
    • Omholt K, Platz A, Ringborg U, Hansson J: Cytoplasmic and nuclear accumulation of beta-catenin is rarely caused by CTNNB1 exon 3 mutations in cutaneous malignant melanoma. Int J Cancer 92: 839-842, 2001
    • (2001) Int J Cancer , vol.92 , pp. 839-842
    • Omholt, K.1    Platz, A.2    Ringborg, U.3    Hansson, J.4
  • 149
    • 0036162726 scopus 로고    scopus 로고
    • Detection of new PTEN/MMAC1 mutations in head and neck squamous cell carcinomas with loss of chromosome 10
    • Poetsch M, Lorenz G, Kleist B: Detection of new PTEN/MMAC1 mutations in head and neck squamous cell carcinomas with loss of chromosome 10. Cancer Genet Cytogenet 132: 20-24, 2002
    • (2002) Cancer Genet Cytogenet , vol.132 , pp. 20-24
    • Poetsch, M.1    Lorenz, G.2    Kleist, B.3
  • 150
    • 3142710392 scopus 로고    scopus 로고
    • Genetic and epigenetic alterations of the APC gene in malignant melanoma
    • Worm J, Christensen C, Gronbaek K, Tulchinsky E, Guldberg P: Genetic and epigenetic alterations of the APC gene in malignant melanoma. Oncogene 23: 5215-5226, 2004
    • (2004) Oncogene , vol.23 , pp. 5215-5226
    • Worm, J.1    Christensen, C.2    Gronbaek, K.3    Tulchinsky, E.4    Guldberg, P.5
  • 152
    • 0036430068 scopus 로고    scopus 로고
    • Pathways to melanoma development: Lessons from the mouse
    • Walker GJ, Hayward NK: Pathways to melanoma development: Lessons from the mouse. J Invest Dermatol 119: 783-792, 2002
    • (2002) J Invest Dermatol , vol.119 , pp. 783-792
    • Walker, G.J.1    Hayward, N.K.2
  • 153
    • 0035328628 scopus 로고    scopus 로고
    • N-cadherin-mediated intercellular interactions promote survival and migration of melanoma cells
    • Li G, Satyamoorthy K, Herlyn M:N-cadherin-mediated intercellular interactions promote survival and migration of melanoma cells. Cancer Res 61: 3819-3825, 2001
    • (2001) Cancer Res , vol.61 , pp. 3819-3825
    • Li, G.1    Satyamoorthy, K.2    Herlyn, M.3


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