BRAF alterations are associated with complex mutational profiles in malignant melanoma

Oncogene

Volumn 23, Issue 35, 2004, Pages 5968-5977

  Daniotti, Maria ^a   Oggionni, Maria ^a   Ranzani, Tiziana ^a   Vallacchi, Viviana ^a   Campi, Valentina ^a   Di Stasi, Delia ^a   Della Torre, Gabriella ^a   Perrone, Federica ^a   Luoni, Chiara ^a   Suardi, Simona ^a   Frattini, Milo ^a   Pilotti, Silvana ^a   Anichini, Andrea ^a   Tragni, Gabrina ^a   Parmiani, Giorgio ^a   Pierotti, Marco A ^a,b   Rodolfo, Monica ^a  

^a NATIONAL CANCER INSTITUTE   (Italy)

^b FIRC INSTITUTE OF MOLECULAR ONCOLOGY   (Italy)

Author keywords

BRAF; CDKN2A; Melanoma; NRAS; PTEN; TP53

Indexed keywords

CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE 4; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN P53; PROTEIN SERINE THREONINE KINASE; RAS PROTEIN; B RAF KINASE; BRAF PROTEIN, HUMAN; CDK4 PROTEIN, HUMAN; CYCLIN DEPENDENT KINASE; ONCOPROTEIN; PHOSPHATASE; PTEN PROTEIN, HUMAN; RAF PROTEIN; TUMOR SUPPRESSOR PROTEIN;

ADULT; AGED; ARTICLE; CANCER CELL CULTURE; CANCER SURVIVAL; CONTROLLED STUDY; FAMILIAL CANCER; FEMALE; GENE EXPRESSION; GENE FUNCTION; GENE LOSS; HUMAN; HUMAN CELL; HUMAN TISSUE; MALE; MELANOMA; MISSENSE MUTATION; MULTIPLE CANCER; MUTATIONAL ANALYSIS; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SKIN CANCER; TUMOR BIOPSY; VISCERAL METASTASIS; GENETICS; MIDDLE AGED; MORTALITY; MUTATION; PROMOTER REGION; TUMOR SUPPRESSOR GENE;

ADULT; AGED; AGED, 80 AND OVER; CYCLIN-DEPENDENT KINASE 4; CYCLIN-DEPENDENT KINASES; FEMALE; GENES, P16; GENES, P53; HUMANS; MALE; MELANOMA; MIDDLE AGED; MUTATION; PHOSPHORIC MONOESTER HYDROLASES; PROMOTER REGIONS (GENETICS); PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS B-RAF; PROTO-ONCOGENE PROTEINS C-RAF; PTEN PHOSPHOHYDROLASE; TUMOR SUPPRESSOR PROTEINS;

EID: 4043055279     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1207780     Document Type: Article

References (44)

1. Albino AP, Nanus DM, Mentle IR, Cordon-Cardo C, McNutt NS, Bressler J and Andreeff M. (1989). Oncogene, 4, 1363-1374.
2. Bertram CG, Gaut RM, Barrett JH, Pinney E, Whitaker L, Turner F, Bataille V, Dos Santos Silva IJ, Swerdlow A, Bishop DT and Newton Bishop JA. (2002). J. Invest. Dermatol., 119, 961-965.
3. Brose MS, Volpe P, Feldman M, Kumar M, Rishi I, Gerrero R, Einhorn E, Herlyn M, Minna J, Nicholson A, Roth JA, Albelda SM, Davies H, Cox C, Brignell G, Stephens PP, Futreal A, Wooster R, Stratton MR and Weber BL. (2002). Cancer Res., 62, 6997-7000.
4. Cascinelli N, Belli F, MacKie RM, Santinami M, Bufalino R and Morabito A. (2001). Lancet, 358, 866-869.
5. Castellano M and Parmiani G. (1999). Melanoma Res., 9, 421-432.
6. Castellano M, Pollock PM, Walters MK, Sparrow LE, Down LM, Gabrielli BG, Parsons PG and Hayward NK. (1997). Cancer Res., 57, 4868-4875.
7. Ceha HM, Nasser I, Medema RH and Slebos RJ. (1998). Biochem. Biophys. Res. Commun., 249, 550-555.
8. Davies H, Bignell GR, Cox C, Stephens P, Edkins S, Clegg S, Teague J, Woffendin H, Garnett MJ, Bottomley W, Davis N, Dicks E, Ewing R, Floyd Y, Gray K, Hall S, Hawes R, Hughes J, Kosmidou V, Menzies A, Mould C, Parker A, Stevens C, Watt S, Hooper S, Wilson R, Jayatilake H, Gusterson BA, Cooper C, Shipley J, Hargrave D, Pritchard-Jones K, Maitland N, Chenevix-Trench G, Riggins GJ, Bigner DD, Palmieri G, Cossu A, Flanagan A, Nicholson A, Ho JW, Leung SY, Yuen ST, Weber BL, Seigler HF, Darrow TL, Paterson H, Marais R, Marshall CJ, Wooster R, Stratton MR and Futreal PA. (2002). Nature, 417, 949-954.
9. Deichmann M, Thome M, Benner A, Egner U, Hartschuh W and Näher H. (2002). Br. J. Cancer, 87, 1431-1436.
10. Dong J, Phelps RG, Qiao R, Yao S, Benard O, Ronai Z and Aaronson SA. (2003). Cancer Res., 63, 3883-3885.
11. Donghi R, Longoni A, Pilotti S, Michieli P, Della Porta G and Pierotti MA. (1993). J. Clin. Invest., 91, 1753-1760.
12. Eskandarpour M, Hashemi J, Kanter L, Ringborg U, Platz A and Hansson J. (2003). J. Natl Cancer Inst., 95, 790-798.
13. Esteller M, Tortola S, Toyota M, Capella G, Peinado MA, Baylin SB and Herman JG. (2000). Cancer Res., 60, 129-133.
14. Eychène A, Dusanter-Fourt I, Barnier JV, Papin C, Charon M, Gisselbrecht S and Calothy G. (1995). Oncogene, 10, 1159-1165.
15. Fargnoli MC, Chimenti S, Keller G, Soyer HP, Dal Pozzo V, Hofler H and Peris K. (1998). J. Invest. Dermatol., 111, 1202-1206.
16. Frisk T, Foukakis T, Dwight T, Lundberg J, Höög A, Wallin G, Eng C, Zedenius J and Larsson C. (2002). Genes, Chromosomes & Cancer, 35, 74-80.
17. Gorden A, Osman I, Gai W, He D, Huang W, Davidson A, Houghton AN, Busam K and Polsky D. (2003). Cancer Res., 63, 3955-3957.
18. Guldberg P, thor Straten P, Birck A, Ahrenkiel V, Kirkin AF and Zeuthen J. (1997). Cancer Res., 57, 3660-3663.
19. Harris CC. (1996). Br. J. Cancer, 73, 261-269.
20. Hashemi J, Lindstrom MS, Asker C, Platz A, Hansson J and Wiman KG. (2002). Cancer Lett., 180, 211-221.
21. Hayward NK. (2003). Oncogene, 22, 3053-3062.
22. Hayward NK. (1999). Molecular Pathology of Early Cancer, Srivastava S, Henson DE, Gazdar A. (eds.). IOS Press: Amsterdam, pp. 207-231.
23. Hussein MR, Haemel AK and Wood GS. (2003). Eur J Cancer Prev., 12, 93-100.
24. Ku JL, Kim WH, Lee JH, Park HS, Kim KH, Sung MW and Park JG. (1999). Laryngoscope, 109, 976-982.
25. Kumar R, Angelini S, Czene K, Sauroja I, Hahka-Kemppinen M, Pyrhönen S and Hemminki K. (2003a). Clin. Cancer Res., 9, 3362-3368.
26. Kumar R, Angelini S and Hemminki K. (2003b). Oncogene, 22, 9217-9224.
27. Lupetti R, Sensi M, Mortarini R, Anichini A, Clemente C and Parmiani G. (1994). Melanoma Res., 4, 11-19.
28. Miller SA, Dykes DD and Polesky HF. (1988). Nucleic Acids Res., 16, 1215-1221.
29. Papp T, Jafari M and Schiffmann DJ. (1996). Cancer Res. Clin. Oncol., 122, 541-548.
30. Pollock PM and Trent JM. (2000). Clin. Lab. Med., 20, 667-690.
31. Pollock PM, Harper UL, Hansen KS, Yudt LM, Stark M, Robbins CM, Moses TY, Hostetter G, Wagner U, Kakareka J, Salem G, Pohida T, Heenan P, Duray P, Kallioniemi O, Hayward NK, Trent JM and Meltzer PS. (2003). Nat Genet., 33, 19-20.
32. Ragnarsson-Olding BK, Karsberg S, Platz A and Ringborg UK. (2002). Melanoma Res., 12, 453-463.
33. Rizos H, Darmanian AP, Holland EA, Mann GJ and Kefford RF. (2001). J. Biol. Chem., 276, 41424-41434.
34. Ruas M and Peters G. (1998). Biochim. Biophys. Acta, 1378, F115-F177.
35. Satyamoorthy K, Li G, Gerrero MR, Brose MS, Volpe P, Weber BL, Van Belle P, Elder DE and Herlyn M. (2003). Cancer Res., 63, 756-759.
36. Trotman L and Pandolfi P. (2003). Cancer Cell, 3, 97-99.
37. Tsao H, Zhang X, Fowlkes K and Haluska FG. (2000). Cancer Res., 60, 1800-1804.
38. Tsao H, Goel V, Wu H, Yang G and Haluska FG. (2004). J. Invest. Dermatol., 122, 337-341.
39. Walker GJ and Hayward NK. (2002). J Invest Dermatol., 119, 783-792.
40. Wolfel T, Hauer M, Schneider J, Serrano M, Wolfel C, Klehmann-Hieb E, De Plaen E, Hankeln T, Meyer zum Buschenfelde KH and Beach D. (1995). Science, 269, 1281-1284.
41. Wu H, Goel V and Haluska FG. (2003). Oncogene, 22, 3113-3122.
42. Zerp SF, van Elsas A, Peltenburg LT and Schrier PI. (1999). Br. J. Cancer, 79, 921-926.
43. Zhang Y and Xiong Y. (1999). Mol. Cell, 3, 579-591.
44. Zhou XP, Gimm O, Hampel H, Niemann T, Walker MJ and Eng C. (2000). Am. J. Pathol., 157, 1123-1128.