Mutation of B-Raf in Human Choroidal Melanoma Cells Mediates Cell Proliferation and Transformation through the MEK/ERK Pathway

Journal of Biological Chemistry

Volumn 278, Issue 43, 2003, Pages 42409-42418

  Calipel, Armelle ^a   Lefevre, Gaelle ^a   Pouponnot, Celio ^b   Mouriaux, Frédéric ^a   Eychène, Alain ^b   Mascarelli, Frédéric ^a  

^a CENTRE DE RECHERCHE DES CORDELIERS   (France)

^b INSTITUT CURIE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYST ACTIVITY; CELLS; MUTAGENESIS; TUMORS;

HUMAN CANCERS;

ENZYMES;

B RAF KINASE; CELL CYCLE PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE; RAF PROTEIN; RNA; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ANCHORAGE INDEPENDENT GROWTH; ARTICLE; CELL LINE; CELL PROLIFERATION; CELL TRANSFORMATION; CHOROID MELANOMA; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; GENE MUTATION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION;

CELL CYCLE PROTEINS; CELL DIVISION; CHOROID NEOPLASMS; GENE EXPRESSION PROFILING; HUMANS; MAP KINASE KINASE 1; MELANOMA; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; MITOGEN-ACTIVATED PROTEIN KINASES; MUTATION; ONCOGENE PROTEINS; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS B-RAF; RAS PROTEINS; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TUMOR CELLS, CULTURED;

EID: 0142211228     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M308709200     Document Type: Article

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