Inhibition of growth and invasive ability of melanoma by inactivation of mutated BRAF with lentivirus-mediated RNA interference

Oncogene

Volumn 23, Issue 36, 2004, Pages 6031-6039

  Sumimoto, Hidetoshi ^a   Miyagishi, Makoto ^b   Miyoshi, Hiroyuki ^c   Yamagata, Shizuko ^a   Shimizu, Ayako ^a   Taira, Kazunari ^b   Kawakami, Yutaka ^a  

^a KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c RIKEN TSUKUBA INSTITUTE   (Japan)

Author keywords

BRAF; Gene therapy; Lentiviral vector; MAPK; Melanoma; RNAi

Indexed keywords

B RAF KINASE; LENTIVIRUS VECTOR; MATRIGEL; MATRIX METALLOPROTEINASE; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN; RNA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CANCER INVASION; CELL GROWTH; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; FEMALE; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS; IN VITRO STUDY; IN VIVO STUDY; MELANOMA; MELANOMA CELL; MOUSE; MUTATION; NONHUMAN; PRIORITY JOURNAL; RNA INTERFERENCE; WILD TYPE;

CELL DIVISION; CELL LINE, TUMOR; GENE THERAPY; GENETIC VECTORS; HUMANS; LENTIVIRUS; MAP KINASE KINASE 1; MELANOMA; MITOGEN-ACTIVATED PROTEIN KINASES; MUTATION; NEOPLASM INVASIVENESS; PROTO-ONCOGENE PROTEINS A-RAF; PROTO-ONCOGENE PROTEINS B-RAF; RNA INTERFERENCE; RNA, SMALL INTERFERING;

ANIMALIA; HUMAN IMMUNODEFICIENCY VIRUS; LENTIVIRUS;

EID: 4444240325     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1207812     Document Type: Article

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