In utero gene therapy: Current challenges and perspectives

Molecular Therapy

Volumn 11, Issue 5, 2005, Pages 661-676

  Waddington, Simon N ^a   Kramer, M Gabriela ^b   Hernandez Alcoceba, Ruben ^b   Buckley, Suzanne M K ^a   Themis, Michael ^a   Coutelle, Charles ^a   Prieto, Jesus ^b,c  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF NAVARRA   (Spain)

^c UNIVERSITY CLINIC OF NAVARRA   (Spain)

Author keywords

Gene therapy; In utero; Vectors

Indexed keywords

ADENOVIRUS VECTOR; BETA GALACTOSIDASE; BLOOD CLOTTING FACTOR 8; BLOOD CLOTTING FACTOR 9; COMPLEMENTARY DNA; DYSTROPHIN; GENE PRODUCT; HELICASE; LENTIVIRUS VECTOR; LEVO IDURONIDASE; LIPOSOME; MEMBRANE PROTEIN; METHYLTRANSFERASE; PARVOVIRUS VECTOR; PLASMID VECTOR; POLYETHYLENEIMINE; PROTEIN LEVO ISOASPARTYL METHYLTRANSFERASE; RETINAL PIGMENT EPITHELIUM GENE PROTEIN; RETROVIRUS VECTOR; UNCLASSIFIED DRUG;

ADENO ASSOCIATED VIRUS; ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION; AMINO ACID METABOLISM; BLINDNESS; BLOOD PLACENTA BARRIER; CELLULAR IMMUNITY; CRIGLER NAJJAR SYNDROME; CYSTIC FIBROSIS; DUCHENNE MUSCULAR DYSTROPHY; EPIDERMOLYSIS BULLOSA; EX VIVO STUDY; FEASIBILITY STUDY; FETUS; FETUS DEVELOPMENT; GENE EXPRESSION; GENE THERAPY; GENETIC ANALYSIS; GENETIC DISORDER; GESTATIONAL AGE; HEMOGLOBINOPATHY; HEMOPHILIA A; HEMOPHILIA B; HUMAN; HUMORAL IMMUNITY; IMMUNE DEFICIENCY; IMMUNE RESPONSE GENE; IMMUNOLOGICAL TOLERANCE; IN UTERO GENE THERAPY; IN UTERO STEM CELL TRANSPLANTATION; LYSOSOME STORAGE DISEASE; MARKER GENE; METABOLIC DISORDER; MOUSE STRAIN; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; NONVIRAL GENE THERAPY; REVIEW; SYMPTOMATOLOGY; VIRAL GENE DELIVERY SYSTEM; VIRAL GENE THERAPY;

ANIMALS; FEMALE; FETUS; GENE THERAPY; GENETIC DISEASES, INBORN; GENETIC VECTORS; HUMANS; PREGNANCY; UTERUS;

EID: 17744367655     PISSN: 15250016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ymthe.2005.01.015     Document Type: Review

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