Long-term correction of bilirubin UDPglucuronyltransferase deficiency in rats by in utero lentiviral gene transfer

Molecular Therapy

Volumn 8, Issue 4, 2003, Pages 593-599

  Seppen, Jurgen ^a   van der Rijt, Roos ^a   Looije, Norbert ^a   van Til, Niek P ^a   Lamers, Wouter H ^a   Oude Elferink, Ronald P J ^a  

^a ACADEMIC MEDICAL CENTER   (Netherlands)

Author keywords

Bilirubin; Crigler Najjar syndrome; Gene therapy; Glucuronosyltransferase; Gunn rat; Lentivirus; Liver; Prenatal diagnosis

Indexed keywords

BILIRUBIN; BILIRUBIN GLUCURONIDE; GLUCURONOSYLTRANSFERASE; LENTIVIRUS VECTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BILE; BILIRUBIN BLOOD LEVEL; CONTROLLED STUDY; CRIGLER NAJJAR SYNDROME; DRUG DISTRIBUTION; DRUG TISSUE LEVEL; ENZYME ACTIVITY; ENZYME DEFICIENCY; FEMALE; FETUS; GENE TRANSFER; GENETIC TRANSDUCTION; GENETIC TRANSFECTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IMMUNOHISTOCHEMISTRY; INTESTINE; INTESTINE EPITHELIUM CELL; LIVER; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; PANCREAS; PANCREAS ISLET CELL; RAT; STOMACH; THIRD TRIMESTER PREGNANCY; TISSUE DISTRIBUTION; VIRAL GENE DELIVERY SYSTEM;

ANIMALIA; LENTIVIRUS; RATTUS NORVEGICUS;

EID: 0142181993     PISSN: 15250016     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1525-0016(03)00234-X     Document Type: Article

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