Sustained delivery of therapeutic concentrations of human clotting factor IX - A comparison of adenoviral and AAV vectors administered in utero

Journal of Gene Medicine

Volumn 4, Issue 1, 2002, Pages 46-53

  Schneider, Holm ^a,b   Mühle, Christiane ^a,b   Douar, Anne Marie ^c   Waddington, Simon ^d   Jiang, Qiu Jie ^a   von der Mark, Klaus ^b   Coutelle, Charles ^d   Rascher, Wolfgang ^a  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^b UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^c GÉNÉTHON   (France)

^d UK Cystic Fibrosis Gene Therapy Consortium   (United Kingdom)

Author keywords

Adeno associated virus; Adenovirus; Factor IX; Gene transfer; Haemophilia B; In utero

Indexed keywords

ADENOVIRUS VECTOR; BLOOD CLOTTING FACTOR 9; COMPLEMENTARY DNA; PARVOVIRUS VECTOR; ANTIBODY;

ANIMAL TISSUE; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; DRUG BLOOD LEVEL; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FETUS; GENE EXPRESSION; IMMUNE RESPONSE; IMMUNOHISTOCHEMISTRY; INTERMETHOD COMPARISON; MALE; MOUSE; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; REPORTER GENE; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE; TRANSGENE; VIRAL GENE DELIVERY SYSTEM; ADENO ASSOCIATED VIRUS; ADENOVIRUS; ANIMAL; C57BL MOUSE; COMPARATIVE STUDY; GENE THERAPY; GENE TRANSFER; GENE VECTOR; GENETICS; HEMOPHILIA B; MUSCLE; PREGNANCY; PRENATAL CARE; TRANSGENIC MOUSE;

ADENO-ASSOCIATED VIRUS; ADENOVIRIDAE;

ADENOVIRIDAE; ANIMALS; ANTIBODIES; DEPENDOVIRUS; DNA, COMPLEMENTARY; FACTOR IX; FEMALE; FETUS; GENE THERAPY; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; HEMOPHILIA B; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MUSCLES; PREGNANCY; PRENATAL CARE;

EID: 0036371236     PISSN: 1099498X     EISSN: None     Source Type: Journal    
DOI: 10.1002/jgm.233     Document Type: Article

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