Long-term transgene expression by administration of a lentivirus-based vector to the fetal circulation of immuno-competent mice

Gene Therapy

Volumn 10, Issue 15, 2003, Pages 1234-1240

  Waddington, S N ^a   Mitrophanous, K A ^b   Ellard, F M ^b   Buckley, S M K ^a   Nivsarkar, M ^a   Lawrence, L ^c   Cook, H T ^b   Al Allaf, F ^a   Bigger, B ^a   Kingsman, S M ^b   Coutelle, C ^a   Themis, M ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b OXFORD BIOMEDICA UK LTD   (United Kingdom)

^c NONE

Author keywords

Broad organ transduction; Fetal gene transfer; Lentivirus vector

Indexed keywords

BETA GALACTOSIDASE; VIRUS VECTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; BRAIN; CELL CLONE; CONTROLLED STUDY; CYTOMEGALOVIRUS; EQUINE INFECTIOUS ANEMIA VIRUS; FETUS; GENE EXPRESSION; GENETIC TRANSDUCTION; HEART; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNOCOMPETENCE; KIDNEY; LENTIVIRINAE; LIVER; LIVER CELL; LUNG; MOUSE; MUSCLE; NEWBORN; NONHUMAN; PERINATAL PERIOD; PRIORITY JOURNAL; PROMOTER REGION; REVIEW; STEM CELL; TRANSGENE; VESICULAR STOMATITIS VIRUS; VIRAL GENE DELIVERY SYSTEM; VIRUS ATTENUATION; VIRUS LOAD;

ANIMALS; FEMALE; FETAL DISEASES; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE THERAPY; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; IMMUNOCOMPETENCE; LENTIVIRUS; LIVER; MICE; MICE, INBRED STRAINS; POLYMERASE CHAIN REACTION; TRANSDUCTION, GENETIC; TRANSGENES; VIRUS REPLICATION;

ANIMALIA; CUCUMBER MOSAIC VIRUS; CYTOMEGALOVIRUS; EQUIDAE; EQUINE INFECTIOUS ANEMIA VIRUS; LENTIVIRUS; VESICULAR STOMATITIS VIRUS;

EID: 0042674017     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3301991     Document Type: Review

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