In utero injection of α-L-iduronidase-carrying retrovirus in canine mucopolysaccharidosis type I: Infection of multiple tissues and neonatal gene expression

Human Gene Therapy

Volumn 13, Issue 15, 2002, Pages 1809-1820

  Meertens, Lisa ^a   Kohn, Donald ^d   Kruth, Stephen ^b   Hough, Margaret R ^a,f   Dubé, Ian D ^a,f   Zhao, Yongjun ^a   Rosic Kablar, Suzana ^a   Li, Liheng ^a   Chan, Kin ^a   Dobson, Howard ^b   Gartley, Cathy ^c   Lutzko, Carolyn ^a,d   Hopwood, John ^e  

^a SUNNYBROOK RESEARCH INSTITUTE   (Canada)

^b UNIVERSITY OF GUELPH   (Canada)

^c UNIVERSITY OF GUELPH   (Canada)

^d UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^e WOMEN S AND CHILDREN S HOSPITAL   (Australia)

^f UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; LEVO IDURONIDASE; RECOMBINANT ENZYME; RETROVIRUS VECTOR; VIRUS DNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL TYPE; CONTROLLED STUDY; DOG; DRUG EFFICACY; ENZYME ACTIVITY; ENZYME DEFICIENCY; FETUS; FIBROBLAST; GENE EXPRESSION; GENE TRANSFER; GENETIC TRANSDUCTION; KIDNEY; LIVER; MUCOPOLYSACCHARIDOSIS; NEWBORN; NONHUMAN; STILLBIRTH; TRANSGENE; VIRAL GENE DELIVERY SYSTEM; VIRUS INFECTION; VIRUS RECOMBINANT;

ANIMALS; ANIMALS, NEWBORN; CELLS, CULTURED; DISEASE MODELS, ANIMAL; DNA, COMPLEMENTARY; DOGS; FEMALE; FETAL DISEASES; FIBROBLASTS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE THERAPY; GENETIC VECTORS; HUMANS; IDURONIDASE; INJECTIONS; INJECTIONS, INTRAPERITONEAL; JURKAT CELLS; KIDNEY; LIVER; MUCOPOLYSACCHARIDOSIS I; PREGNANCY; TISSUE DISTRIBUTION; TRANSDUCTION, GENETIC; YOLK SAC;

ANIMALIA; CANIS FAMILIARIS; DNA VIRUSES; UNIDENTIFIED RETROVIRUS;

EID: 0036412405     PISSN: 10430342     EISSN: None     Source Type: Journal    
DOI: 10.1089/104303402760372918     Document Type: Article

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