Comparative developmental anatomy of the murine and human definitive placentae

Placenta

Volumn 23, Issue 1, 2002, Pages 3-19

  Georgiades, P ^a   Fergyson Smith, A C ^a   Burton, G J ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE TRANSPORTER 1; RETINOID X RECEPTOR ALPHA; VASCULOTROPIN;

BLOOD TRANSFUSION; CELL INTERACTION; CELL STRUCTURE; CELL TYPE; COMPARATIVE STUDY; DECIDUA; FETUS GROWTH; GENE EXPRESSION; GENETIC ANALYSIS; GIANT CELL; HUMAN; HUMAN VERSUS ANIMAL COMPARISON; INTRAUTERINE GROWTH RETARDATION; MOTHER FETUS RELATIONSHIP; MOUSE STRAIN; NONHUMAN; PLACENTA DEVELOPMENT; PLACENTA DISORDER; PRIORITY JOURNAL; REPRODUCTION; REVIEW; SPONTANEOUS ABORTION; TROPHOBLAST; UTERUS; ADULT; ANIMAL; FEMALE; FETOMATERNAL TRANSFUSION; GENE EXPRESSION REGULATION; GENETICS; MOUSE; PLACENTA; PREGNANCY; PRENATAL DEVELOPMENT; SPECIES DIFFERENCE;

ADULT; ANIMALS; EMBRYONIC AND FETAL DEVELOPMENT; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HUMANS; MATERNAL-FETAL EXCHANGE; MICE; PLACENTA; PREGNANCY; SPECIES SPECIFICITY;

EID: 0036365762     PISSN: 01434004     EISSN: None     Source Type: Journal    
DOI: 10.1053/plac.2001.0738     Document Type: Review

References (124)

1. Adamson SL, Whiteley KJ, Lu Y & Cross JC (2000) Structure of the maternal circulation of the mouse placenta. Placenta, 21, A87.
2. Aherne W & Dunnill MS (1966) Quantitative aspects of placental structure. J Path Bact, 91, 123-139.
3. Ahmed A, Li XF, Dunk C, Whittle MJ, Rushton DI & Rollanson T (1995) Colocalisation of vascular endothelial factor and its Flt-1 receptor in human placenta. Growth Factors, 12, 253-243.
4. Alders M, Hodges M, Hadjantonakis A-K, Postmus J, van Wijk I, Bliek J, de Meulemeester M, Westerveld A, Guillemot F, Oudejans C, Little P & Mannens M (1997) The human Achaete-Scute homologue 2 (ASCL2,HASH2) maps to chromosome 11p15.5, close to IGF2 and is expressed in extravillus trophoblasts. Human Mol Genet, 6, 859-867.
5. Allen WR (1975) Endocrine functions of the placenta. In Comparative Placentation (Ed.) Steven DH, pp. 214-267. London: Academic Press.
6. Basyuk E, Cross JC, Corbin J, Nakayama H, Hunter P, Nait-Oumesmar B & Lazzarini RA (1999) Murine Gcm1 gene is expressed in a subset of placental trophoblast cells. Dev Dyn, 214, 303-311.
7. Bell SC (1983) Decidualization: regional differentiation and associated function. Oxford Reviews of Reproductive Biology, 5, 220-271.
8. Bevilacqua EM & Abraham sohn PA (1989) Trophoblast invasion during implantation of the mouse embryo. Arch Biol Med Exp, 22, 107-118.
9. Bianchi DW, Wilkins-Haug LE, Enders AC & Hay ED (1993) Origin of extraembryonic mesoderm in experimental animals: Relevance to chorionic mosaicism in humans. Am J Med Genet, 46, 542-550.
10. Birchmeier C & Gherardi E (1998) Developmental roles of HGF/SF and its receptor the c-Met tyrosine kinase. Trends in Cell Bio, 8, 404-410.
11. Blackburn MR, Wakamiya M, Caskey CT & Kellems RE (1995) Tissue-specific rescue suggests that placental adenosine deaminase is important for fetal development in mice. J Biol Chem, 270, 23891-23894.
12. Bladt F, Rietmacher D, Isenmann S, Aguzzi A & Birchmeier C (1995) Essential role for the c-met receptor in the migration of myogenic precursor cells into the limb bud. Nature, 376, 768-771.
13. Borland R (1975) Placenta as an allograft. In Comparative Placentation (Ed.) Steven DH, pp. 268-281. London: Academic Press.
14. Breier G, Clauss M & Risau W (1995) Coordinate expression of vascular endothelial growth factor receptor-1 (flt-1) and its ligand suggests a paracrine regulation of murine vascular development. Dev Dyn, 204, 228-239.
15. Brosens I, Robertson WB & Dixon HG (1967) The physiological response of the vessels of the placental bed to normal pregnancy. J Path Bact, 93, 569-579.
16. Brown RW, Diaz R, Robson AC, Kotelevtsev YV, Mullins JJ, Kaufman MH & Seckl JR (1996) The ontogeny of 11 beta-hydroxysteroid dehydrogenase type 2 and mineralocorticoid receptor gene expression reveal intricate control of glucocorticoid action in development. Endocrinology, 137, 794-797.
17. Bulmer JN, Smith J, Morrison L & Wells M (1988) Maternal and fetal cellular relationships in the human placental basal plate. Placenta, 9, 237-246.
18. Burton GJ, Jauniaux E & Watson AL (1999) Maternal arterial connections to the placenta intervillous space during the first trimester of human pregnancy: the Boyd collection revisited. Am J Obstet Gynecol, 181, 718-724.
19. Burton GJ, Hempstock J & Jauniaux E (2001) Nutrition of the human fetus during the first trimester-a review. Placenta, 22(A), S70-S76.
20. Calzonetti T, Stevenson L & Rossant J (1995) A novel regulatory region is required for trophoblast-specific transcription in transgenic mice. Dev Biol, 171, 615-626.
21. Carter AM (1975) Placental circulation. In Comparative Placentation (Ed.) Steven DH, pp. 108-160. London: Academic Press.
22. Charnock-Jones DS, Sharkey AM, Broocock CA, Pelvin R, Ferrara N & Smith SK (1994) Vascular endothelial growth factor receptor localization and activation in human trophoblast and choriocarcinoma cells. Biol Reprod, 51, 524-530.
23. Chilosi M, Piazzola E, Lestani M, Benedetti A, Guasparri I, Granchelli G, Aldovini D, Leonardi E, Pizzolo G, Doglion C, Menestrina F & Mariuzzi GM (1998) Differential expression of p57Kip2, a maternally imprinted cdk inhibitor, in normal human placenta and gestational trophoblastic disease. Lab Invest, 78, 269-276.
24. Craven CM & Ward K (1999) Syncytiotrophoblastic fragments in first-trimester decidual veins: evidence of placental perfusion by the maternal circulation early in pregnancy. Am J Obstet Gynecol, 181, 455-459.
25. Cross JC, Werb Z & Fisher SJ (1994) Implantation and the placenta: key pieces of the developing puzzle. Science, 266, 1508-1518.
26. Cross JC (2000) Genetic insights into trophoblast differentiation and placental morphogenesis. Sem Cell Dev Biol, 11, 105-113.
27. Damsky CH, Fitzgerald ML & Fisher SJ (1992) Distribution patterns of extracellular matrix components and adhesion receptors are intrcately modulated during first trimester cytotrophoblast differentiation along the invasive pathway in vivo. J Clin Invest, 89, 210-222.
28. Davies J & Glasser SR (1968) Histological and fine structural observations on the placenta of the rat. Acta Anat, 69, 542-608.
29. Demir R, Kosanke G, Kohnen G, Kertschanska S & Kaufmann P (1997) Classification of human placental stem villi: review of structural and functional aspects. Microsc Res Tech, 38, 29-41.
30. Dietrich S, Abou-Rebyeh F, Brohmann H, Bladt F, Sonnerberg-Riethmacher E, Yamaai T, Lumsden A, Brand-Saber B & Birchmeier C (1999) The role of SF/HGF and c-Met in the development of skeletal muscle. Development, 126, 1621-1629.
31. Dumont DJ, Fong G-H, Puri MC, Grandwohl G, Alitalo K & Breitman ML (1995) Vascularization of the mouse embryo: a study of flk-1, tek, tie, and vascular endothelial growth factor expression during development. Dev Dyn, 203, 80-92.
32. Enders AS (1965) A comparative study of the fine structure of the trophoblast in several hemochorial placentas. Am J Anat, 116, 29-68.
33. Farnsworth RL & Talamantes F (1998) Calyclin in the mouse decidua: expression and effects on placental lactogen secretion. Biol Reprod, 59, 546-552.
34. Frank HG, Malekzadeh F, Kertschanska S, Crescimanno C, Catellucci M, Lang I, Desoye G & Kaufmann P (1994) Immunohistochemistry of two diferent types of placental fibrinoid. Acta Anat, 150, 55-68.
35. Gardner RL (1985) Origin and development of the trophectoderm and inner cell mass. In Implantation of the Human Embryo (Eds) Edwards RG, Purdy JM & Steptoe PC, pp. 155-178. London: Academic Press.
36. Georgiades P, Watkins M, Burton J & Ferguson-Smith (2001) Roles for genomic imprinting and the zygotic genome in placental development. Proc Natl Acad Sci USA, 98, 4522-4527.
37. Gnarra JR, Ward JM, Porter FD, Wagner JR, Devor DE, Grniberg A, Emmert-Buck MR, Westphal H & Klausner RD (1997) Defective placental vasculogenesis causes embryonic lethality in VHL-deficient mice. Proc Natl Acad Sci USA, 94, 9102-9107.
38. Guibourdenche J, Alsat E, Soncin F, Rochette-Egly C & Evain-Brion D (1998) Retinoid receptors expression in human term placenta: involvement of RXR alpha in retinoid induced-hCG secretion. J Clin Endocrinol Metab, 83, 1384-1387.
39. Gulbis B, Jauniaux E, Cotton F & Stordeur P (1998) Protein and enzyme patterns in the fluid cavities of the first trimester gestational sac: relevance to the absorptive role of the secondary yolk sac. Human Reproduction, 4, 857-862.
40. Hahn T, Barth S, Graf R, Engelmann M, Beslagic D, Reul JM, Holsboer F, Dohr G & Desoye G (1999) Placental glucose transporter expression is regulated by glucocorticoids. J Clin Endocrinol Metab, 84, 1445-1452.
41. Haigh T, Chen CP, Jones CJP & Aplin JD (1999) Studies of mesenchymal cells from 1st trimester human placenta: expression of cytokeratin outside the trophoblast lineage. Placenta, 20, 615-625.
42. Han VKM & Carter AM (2000) Spatial and temporal patterns of expression of messenger RNA for Insulin-like factors and their binding proteins in the placenta of man and laboratory animals. Placenta, 21, 289-305.
43. Handwerger S & Freemark M (2000) The roles of placental growth hormone and placental lactogen in the regulation of human fetal growth and development. J Pediatr Endocrinol Metab, 4, 343-356.
44. Hattori N, Davies TC, Anson-Cartwright L & Cross JC (2000) Periodic expression of the cyclin-dependent kinase inhibitor p57kip2 in trophoblast giant cells defines a G2-like gap phase of the endocycle. Mol Biol Cell, 11, 1037-1045.
45. He Y, Smith SK, Day KA, Clark DE, Licence DR & Charnock-Jones S (1999) Alternative spilicing of vascular endothelial growth factor (VEGF)-R1 (FLT-1) pre-mRNA is important for the regulation of VEGF activity. Mol Endo, 13, 537-545.
46. Heinrich D, Metz J, Raviola E & Forssmann WG (1976) Ultrastructure of perfusion-fixed fetal capillaries in the human placenta. Cell Tissue Res, 172, 157-169.
47. Hellstrom M, Kalen M, Lindahl P, Abramsson A & Betsholtz C (1999) Roles of PDGF-B and PDGFR-β in recruitment of vascular smooth muscle cells and pericytes during embryonic blood vessel formation in the mouse. Development, 126, 3047-3055.
48. Helske S, Vuorela P, Carpen O, Hornig C, Weich H & Halmesmaki E (2001) Expression of vascular endothelial growth factor receptors 1, 2 and 3 in placentas from normal and complicated pregnancies. Mol Hum Reprod, 7, 205-210.
49. Hernandez-Verdun D (1974) Morphogenesis of the Syncytium in the mouse placenta. Cell Tiss Res, 148, 381-396.
50. Hunt JS, Petroff MG & Burnett TG (2000) Uterine leukocytes: key players in pregnancy. Sem Cell Dev Biol, 11, 127-137.
51. Hustin J & Schaaps JP (1987) Echographic and anatomic studies of the maternotrophoblastic border during the first trimester of pregnancy. Am J Obstet Gynecol, 157, 162-168.
52. Hustin J, Jauniaux E & Schaaps JP (1990) Histological study of the materno-embryonic interface in spontaneous abortion. Placenta, 11, 477-486.
53. Iguchi T, Tani N, Sato T, Fucatsu N & Ohta Y (1993) Developmental changes in mouse placental cells from several stages of pregnancy in vivo and in vitro. Biol Reprod, 48, 188-196.
54. Jacquemin P, Sapin V, Alsat E, Evain-Brion D, Dolle P & Davidson I (1998) Differential expression of the TEF family of transcription factors in the murine placenta and during differentiation of primary human trophoblasts in vitro. Dev Dyn, 212, 423-436.
55. Jauniaux E, Burton CJ & Jones CJP (1992) Early human placental morphology. In The First Twelve Weeks of Gestation (Eds) Barnea ER, Hustin J & Jauniaux E, pp. 45-64. Berlin: Springer-Verlag.
56. Jauniaux E & Moscoso JC (1992) Morphology and significance of the human yolk sac. In The First Twelve Weeks of Gestation (Eds) Barnea ER, Hustin J & Jauniaux E, pp. 192-213. Berlin: Springer-Verlag.
57. Jauniaux E, Jurkovic D & Campbell S (1995) In vivo investigation of the placental circulations by Doppler Echography. Placenta, 16, 323-331.
58. Jauniaux E, Watson AL, Hempstock J, Bao Y-P, Skepper JN & Burton GJ (2000) Onset of maternal arterial bloodflow and placental oxidative stress: a possible factor in human early pregnancy failure. Am J Pathol, 157, 3251-3262.
59. Jones CJP (1997) The life and death of the embryonic yolk sac. In Embryonic Medicine and Therapy (Eds) Jauniaux E, Barnea ER & Edwards RG, pp. 180-196. Oxford: Oxford University Press.
60. Kam EPY, Gardner L, Loke YWW & King A (1999) The role of trophoblast in the physiological change in decidual spiral arteries. Human Reproduction, 14, 2131-2138.
61. Kamei Y, Tsutsumi O, Yamakawa A, Oka Y, Taketani Y & Imaki J (1999) Maternal epidermal growth factor deficiency causes fetal hypoglycemia and intrauterine growth retardation in mice: possible involvement of placental glucose transporter GLUT3 expression. Endocrinology, 140, 4236-4243.
62. Kaufman M (1990) Morphological stages of postimplantation embryonic development. In Postimplantation Mammalian Embryos (Eds) Copp AJ & Cockfort DL, pp. 81-92. Oxford: IRL Press.
63. Kaufmann P, Huppertz B & Frank H-G (1996) The fibrinoids of the human placenta: origin, composition and functional significance. Ann Anat, 178, 485-501.
64. Khong TY, De Wolf F, Robertson WB & Brosens I (1986) Inadequate maternal vascular response complicated by pre-eclampsia and by small for gestational age infants. Br J Obstet Gynaecol, 93, 1049-1059.
65. Khong TY, Liddell HS & Robertson WB (1987) Defective haemochorial placentation as a cause of miscarriage: a preliminary study. Br J Obstet Gynaecol, 94, 649-655.
66. King BF (1989) The functional anatomy of the placental vasculature. In The Uterine Circulation (Ed.) Rosenfield CR, pp. 17-33. New York: Perinatology Press.
67. Kirby DRS & Bradbury S (1965) The hemo-chorial mouse placenta. Anat Rec, 152, 279-281.
68. Kliman HJ (2000) Uteroplacental blood flow: the story of decidualization, menstruation, and trophoblast invasion. Am J Pathol, 157, 1759-1768.
69. Kurman RJ, Main CS & Chen H-C (1984) Intermediate trophoblast: a distinctive form of trophoblast with specific morphological, biochemical and functional features. Placenta, 5, 349-370.
70. al-Lamki RS, Skepper JN & Burton GJ (1999) Are human placental bed giant cells merely aggregates of small mononuclear trophoblasts cells? An ultrastructural and immunocytochemical study. Human Reproduction, 13, 496-504.
71. Leach L & Firth JA (1992) Fine structure of the paracellular junctions of erminal villous capillaries in the perfused human placenta. Cell Tissue Res, 268, 447-452.
72. Leiser R, Krebs C, Ebert B & Dantzer V (1997) Placental vascular corrosion cast studies: a comparison between ruminants and humans. Microsc Res Tech, 38, 76-87.
73. Li Y & Behringer RR (1998) Esx1 is an X-chromosome-imprinted regulator of placental development and fetal growth. Nature Genet, 20, 309-311.
74. Loke YW & King A (1995) Human implantation: Cell Biology and Immunology. Cambridge: Cambridge University Press.
75. Louvi A, Accili D & Efstradiadis A (1997) Growth-promoting interaction of IGFII with insulin receptor during mouse embryonic development. Dev Bio, 189, 33-48.
76. Mayer W, Hemberger M, Frank H-G, Grummer R, Winterhager E, Kaufmann P & Fundele R (2000) Expression of the imprinted genes MEST/Mest in human and murine placenta suggests a role in angiogenesis. Dev Dynam, 217, 1-10.
77. Mayhew TM, Wadrop E & Simpson RA (1994) Priliferative versus hypertrophic growth in tisue subcompartments of human placental villi during gestation. J Anat, 184, 535-543.
78. McParland P & Pearce JM (1988) Doppler blood flow in pregnancy. Placenta, 9, 427-450.
79. Meekins JW, Pijnenborg R, Hanssens M, McFadyen IR & Van Asshe A (1994) A study of placenta bed spiral arteries and trophoblast invasion in normal and severe pre-eclamptic pregnencies. Br J Obstet Gynaecol, 101, 669-674.
80. Moll W (1985) Physiological aspects of placenta! ontogeny and phylogeny. Placenta, 6, 141-154.
81. Mossman HW (1937) Comparative morphogenesis of the fetal membranes and accessory uterine structures. Contributions to Embryology, 158, 133-247.
82. Mossman HW (1987) Vertebrate fetal membranes. London: Macmillan Press. 133 pp.
83. Muller H, Ishimura R, Orwig KE, Liu B & Soares MJ (1998) Homologues for prolactin-like proteins A and B are present in the mouse. Biol Reprod, 58, 45-51.
84. Muntener M & Hsu Y-C (1977) Development of trophoblast and placenta of the mouse. Acta Anat, 98, 241-252.
85. Nait-Oumesmar B, Copperman AB & Lazzarini RA (2000) Placental expression and chromosomal localization of the human Gcm 1 gene. J Histochem Cytochem, 48, 915-922.
86. Nakayama H, Scott IC & Cross JC (1998) The transition to endoreduplication in trophoblast giant cells is regulated by the mSNA zinc finger transcription factor. Dev Biol, 199, 150-163.
87. Ohlsson, R, Falck P, Hellstrom M, Lindahl P, Bostrom H, Franklin G, Ahrlund-Richter L, Pollard J, Soriano P & Betsholtz C (1999) PDGFB regulates the development of the labyrinthine layer of the mouse fetal placenta. Dev Biol, 212, 124-136.
88. al-Okail MS & al-Attas OS (1994) Histological changes in placental syncytiotrophoblasts of poorly controlled gestational diabetic patients. Endocr J, 41, 355-360.
89. Pijnenborg R, Dixon G, Robertson WB & Brosens I (1980) Trophoblastic invasion of human decidua from 8 to 18 weeks of pregnacy. Placenta, 1, 3-19.
90. Pijnenborg R, Robertson WB, Brosens I & Dixon G (1981) Trophoblastic invasion and the establishemnt of haemochorial placentation in man and laboratory animals. Placenta, 2, 71-92.
91. Pijnenborg R, Bland JM, Robertson WB & Brosens I (1983) Uteroplacental arterial changes related to interstitial trophoblast migration in early human pregnacy. Placenta, 4, 397-414.
92. Pijnenborg R (1996) The placental bed. Hypertens Pregn, 15, 7-23.
93. Potter, EL (1952) Pathology of the Fetus and the Newborn. Chicago: The Year Book Publishers Inc. 15 pp.
94. Rassoulzadegan M, Rosen BS, Gillot I & Cuzin F (2000) Phagocytosis reveals a reversible differentiated state early in the development of the mouse embryo. EMBO J, 19, 3295-3303.
95. Redline RW & Lu CY (1989) Localization of fetal major histocompatibility complex antigens and maternal leukocytes in murine placenta. Lab Invest, 61, 27-36.
96. Redline RW, Chernicky CL, Tan H-Q, Ilan J & Ilan J (1993) Differential expression of Insulin-like growth factor-II in specific regions of the late (post day 9.5) murine placenta. Mol Reprod Dev, 36, 121-129.
97. Redline RW & Patterson BS (1995) Pre-eclampsia is associated with an excess of proliferative immature intermediate trophoblast. Hum Pathol, 26, 594-600.
98. Redman CWG, McMichael AJ, Stirrat GM, Sunderland CA & Ting A (1984) Class I major histocompatibility complex antigens on human extravillous trophoblast. Immunology, 52, 457-468.
99. Risteli J, Foidart JM, Risteli L, Boniver J & Goffinet G (1984) The basement membrane proteins laminin and type IV collagen in isolated villi in pre-eclampsia. Placenta, 5, 541-550.
100. Rossant J & Spence A (1998) Chimeras and mosaics in mouse mutant analysis. TIG, 14, 358-363.
101. Sakata M, Yamaguchi M, Tadokoro C, Yoshimoto Y, Oka Y, Kurachi H & Miyake A (1996) 8-Bromo-cAMP inhibits glucose transporter activity in mouse placental cells in culture. J Endocrinology, 150, 319-327.
102. Sapin V, Ward SJ, Bronner S, Chambon P & Dolle P (1997a) Differential expression of transcripts encoding retinoid binding proteins and retinoic acid receptors during placentation of the mouse. Dev Dyn, 208, 199-210.
103. Sapin V, Dolle P, Hindelang C, Kastner P & Chambon (1997b) Defects of the chorioallantoic placenta in mouse RXRa null fetuses. Dev Biol, 191, 29-41.
104. Sharkey AM, Charnock-Jones DS, Boocock, Brown KD & Smith SK (1993) Expression of mRNA for endothelial growth factor in human placenta. J Reprod Fertil, 99, 609-615.
105. Somerset DA, Li X-F, Afford S, Strain AJ, Ahmet A, Sangha RK, Whittle MJ & Kilby MD (1998) Ontogeny of Hepatocute Growth Factor (HGF) and its receptor (c-met) in human placenta. Am J Pathol, 153, 1139-1147.
106. Steven D (1975) Anatomy of the placental barrier. In Comparative placentation (Ed.) Steven DH, pp. 25-57. London: Academic Press.
107. Steven D & Morris G (1975) Development of the foetal membranes. In Comparative placentation (Ed.) Steven DH, pp. 58-86. London: Academic Press.
108. Sun K, Yang K & Challis JRG (1997) Differential expression of 11 beta-hydroxysteroid dehydrogenase types 1 and 2 in human placenta and fetal membranes. J Clin Endocrinol Metab, 82, 300-305.
109. Takahashi K, Kobayashi T & Kanayama N (2000) p57Kip2 regulates the proper development of labyrinthine and spongiotrophoblasts. Mol Human Reprod, 6, 1019-1025.
110. Takata K & Hirano H (1997) Mechanism of glucose transport across the human and rat placental barrier: a review. Microsc Res Tech, 38, 145-152.
111. Tanaka M, Gertsenstein M, Rossant J & Nagy A (1997) Mash2 acts cell autonomously in mouse spongiotrophoblast development. Dev Biol, 190, 55-65.
112. Teesalu T, Blasi F & Talarico D (1998) Expression and function of the Urokinase type plasminogen activator during mouse hemochorial placental development. Dev Dyn, 213, 27-38.
113. Uehara Y, Minowa O, Mori C, Shiota K, Kuno J, Noda T & Kitamura N (1995) Placental defect and embryonic lethality in mice lacking hepatocyte growth factor/scatter factor. Nature, 373, 702-705.
114. Varmuza S, Prideaux V, Kothary R & Rossant J (1988) Polytene chromosomes in mouse trophoblast giant cells. Development, 102, 127-134.
115. West JD, Flockhart JH & Keighren M (1995) Biochemical evidence for cell fusion in placentas of mouse aggregation chimeras. Dev Biol, 168, 76-85.
116. Wigglesworth JS (1962) The Langhan layer in late pregnancy: a histological study of normal and abnormal cases. J Obstet Gynaecol Br Commonw, 69, 355-365.
117. Wooding FBP & Flint APF (1994) Placentation. In Marshall's Physiology of Reproduction, Fourth edition (Ed.) Lamming GE, pp. 233-460. London: Chapman and Hall.
118. Wynn RM (1968) Morphology of the placenta. In Biology of Gestation (Ed.) Assali NS, pp. 93-184. New York: Academic Press.
119. Kip2 results in increased apoptosis and delayed differentiation during mouse development. Genes Dev, 11, 973-983.
120. Yeh I-T, O'Connor DM & Kurman RJ (1989) Vacuolated cytotrophoblast: a subpopulation of trophoblast in the chorion laeve. Placenta, 10, 429-438.
121. KIP2 in the control of tissue growth and development. Genes & Dev, 12, 3162-3167.
122. Zhou J & Bondy C (1992) Insulin-like growth factor-II and its binding proteins in placental development. Endocrinology, 131, 1230-1240.
123. Zhou Y, Damsky CH, Chiu K, Roberts JM & Fisher SJ (1993) Preeclampsia is associated with abnormal expression of adhesion molecules by invasive trophoblasts. J Clin Invest, 91, 950-960.
124. Zhou Y, Damsky CH & Fisher SJ (1997) Preeclampsia is associated with failure of human cytotrophoblasts to mimic a vascular adhesion phenotype. J Clin Invest, 99, 2152-2164.