메뉴 건너뛰기




Volumn 6, Issue 10, 1999, Pages 1759-1767

Transduction of axotomized retinal ganglion cells by adenoviral vector administration at the optic nerve stump. An in vivo model system for the inhibition of neuronal apoptotic cell death

Author keywords

Adenovirus; Apoptosis; Axotomy; crmA; p35; Retina

Indexed keywords

MESSENGER RNA; VIRUS VECTOR;

EID: 17644432519     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3301000     Document Type: Article
Times cited : (46)

References (49)
  • 1
    • 0031900347 scopus 로고    scopus 로고
    • Sealing one's fate: Control of cell death in neurons
    • Bergeron L, Yuan J. Sealing one's fate: control of cell death in neurons. Curr Opin Neurobiol 1998; 8: 55-63.
    • (1998) Curr Opin Neurobiol , vol.8 , pp. 55-63
    • Bergeron, L.1    Yuan, J.2
  • 2
    • 0030947095 scopus 로고    scopus 로고
    • Programmed cell death in animal development
    • Jacobson MD, Weil M, Raff MC. Programmed cell death in animal development. Cell 1997; 88: 347-354.
    • (1997) Cell , vol.88 , pp. 347-354
    • Jacobson, M.D.1    Weil, M.2    Raff, M.C.3
  • 3
    • 0030665659 scopus 로고    scopus 로고
    • The role of the bcl-2/ced-9 gene family in cancer and general implications of defects in cell death control for tumourigenesis and resistance to chemotherapy
    • Strasser A, Huang DC, Vaux DL. The role of the bcl-2/ced-9 gene family in cancer and general implications of defects in cell death control for tumourigenesis and resistance to chemotherapy. Biochim Biophys Acta 1997; 1333: 151-178.
    • (1997) Biochim Biophys Acta , vol.1333 , pp. 151-178
    • Strasser, A.1    Huang, D.C.2    Vaux, D.L.3
  • 4
    • 0032525260 scopus 로고    scopus 로고
    • Activation and cleavage of caspase-3 in apoptosis induced by experimental cerebral ischemia
    • Namura S et al. Activation and cleavage of caspase-3 in apoptosis induced by experimental cerebral ischemia. J Neurosci 1998; 18: 3659-3668.
    • (1998) J Neurosci , vol.18 , pp. 3659-3668
    • Namura, S.1
  • 5
    • 0032575694 scopus 로고    scopus 로고
    • Stroke-damaged neurons may commit cellular suicide
    • Barinaga M. Stroke-damaged neurons may commit cellular suicide. Science 1998; 281: 1302-1303.
    • (1998) Science , vol.281 , pp. 1302-1303
    • Barinaga, M.1
  • 6
    • 0031806464 scopus 로고    scopus 로고
    • The temporal profile and morphologic features of neuronal death in human stroke resemble those observed in experimental forebrain ischemia: The potential role of apoptosis
    • Guglielmo MA et al. The temporal profile and morphologic features of neuronal death in human stroke resemble those observed in experimental forebrain ischemia: the potential role of apoptosis. Neurol Res 1998; 20: 283-296.
    • (1998) Neurol Res , vol.20 , pp. 283-296
    • Guglielmo, M.A.1
  • 7
    • 0031442184 scopus 로고    scopus 로고
    • Synergistic anti-apoptotic activity between Bcl-2 and SMN implicated in spinal muscular atrophy
    • Iwahashi H et al. Synergistic anti-apoptotic activity between Bcl-2 and SMN implicated in spinal muscular atrophy. Nature 1997; 390: 413-417.
    • (1997) Nature , vol.390 , pp. 413-417
    • Iwahashi, H.1
  • 8
    • 0030868903 scopus 로고    scopus 로고
    • Alternative cleavage of Alzheimer-associated presenilins during apoptosis by a caspase-3 family protease
    • Kim TW et al. Alternative cleavage of Alzheimer-associated presenilins during apoptosis by a caspase-3 family protease. Science 1997; 277: 373-376.
    • (1997) Science , vol.277 , pp. 373-376
    • Kim, T.W.1
  • 9
    • 0031593685 scopus 로고    scopus 로고
    • Inhibition of presenilin 1 expression is promoted by p53 and p21(WAF-1) and results in apoptosis and tumor suppression
    • Roperch JP et al. Inhibition of presenilin 1 expression is promoted by p53 and p21(WAF-1) and results in apoptosis and tumor suppression. Nature Med 1998; 4: 835-838.
    • (1998) Nature Med , vol.4 , pp. 835-838
    • Roperch, J.P.1
  • 10
    • 0032146787 scopus 로고    scopus 로고
    • Experimental brain injury induces regionally distinct apoptosis during the acute and delayed post-traumatic period
    • Conti AC, Raghupathi R, Trojanowski JQ, McIntosh TK. Experimental brain injury induces regionally distinct apoptosis during the acute and delayed post-traumatic period. J Neurosci 1998; 18: 5663-5672.
    • (1998) J Neurosci , vol.18 , pp. 5663-5672
    • Conti, A.C.1    Raghupathi, R.2    Trojanowski, J.Q.3    McIntosh, T.K.4
  • 11
    • 0030804272 scopus 로고    scopus 로고
    • Activation of CPP32-like caspases contributes to neuronal apoptosis and neurological dysfunction after traumatic brain injury
    • Yakovlev AG et al. Activation of CPP32-like caspases contributes to neuronal apoptosis and neurological dysfunction after traumatic brain injury. J Neurosci 1997; 17: 7415-7424.
    • (1997) J Neurosci , vol.17 , pp. 7415-7424
    • Yakovlev, A.G.1
  • 12
    • 0030931876 scopus 로고    scopus 로고
    • Caspases: The executioners of apoptosis
    • Cohen GM. Caspases: the executioners of apoptosis. Biochem J 1997; 326: 1-16.
    • (1997) Biochem J , vol.326 , pp. 1-16
    • Cohen, G.M.1
  • 13
    • 0032575714 scopus 로고    scopus 로고
    • Death receptors: Signaling and modulation
    • Ashkenazi A, Dixit VM. Death receptors: signaling and modulation. Science 1998; 281: 1305-1308.
    • (1998) Science , vol.281 , pp. 1305-1308
    • Ashkenazi, A.1    Dixit, V.M.2
  • 14
    • 0031934936 scopus 로고    scopus 로고
    • Microglia-derived nerve growth factor causes cell death in the developing retina
    • Frade JM, Barde YA. Microglia-derived nerve growth factor causes cell death in the developing retina. Neuron 1998; 20: 35-41.
    • (1998) Neuron , vol.20 , pp. 35-41
    • Frade, J.M.1    Barde, Y.A.2
  • 15
    • 0030766381 scopus 로고    scopus 로고
    • Control of early cell death by BDNF in the chick retina
    • Frade JM et al. Control of early cell death by BDNF in the chick retina. Development 1997; 124: 3313-3320.
    • (1997) Development , vol.124 , pp. 3313-3320
    • Frade, J.M.1
  • 16
    • 0032575752 scopus 로고    scopus 로고
    • Mitochondria and apoptosis
    • Green DR, Reed JC. Mitochondria and apoptosis. Science 1998; 281: 1309-1312.
    • (1998) Science , vol.281 , pp. 1309-1312
    • Green, D.R.1    Reed, J.C.2
  • 18
    • 0028041471 scopus 로고
    • Apoptotic cell death induced by optic nerve lesion in the neonatal rat
    • Rabacchi SA, Bonfanti L, Liu XH, Maffei L. Apoptotic cell death induced by optic nerve lesion in the neonatal rat. J Neurosci 1994; 14: 5292-5301.
    • (1994) J Neurosci , vol.14 , pp. 5292-5301
    • Rabacchi, S.A.1    Bonfanti, L.2    Liu, X.H.3    Maffei, L.4
  • 19
    • 0030851891 scopus 로고    scopus 로고
    • Up-regulation of bax protein in degenerating retinal ganglion cells precedes apoptotic cell death after optic nerve lesion in the rat
    • Isenmann S et al. Up-regulation of Bax protein in degenerating retinal ganglion cells precedes apoptotic cell death after optic nerve lesion in the rat. Eur J Neurosci 1997; 9: 1763-1772.
    • (1997) Eur J Neurosci , vol.9 , pp. 1763-1772
    • Isenmann, S.1
  • 20
    • 0031940544 scopus 로고    scopus 로고
    • Free radical scavenging and inhibition of nitric oxide synthase potentiates the neurotrophic effects of brain-derived neurotrophic factor on axotomized retinal ganglion cells in vivo
    • Klöcker N, Cellerino A, Bähr M. Free radical scavenging and inhibition of nitric oxide synthase potentiates the neurotrophic effects of brain-derived neurotrophic factor on axotomized retinal ganglion cells in vivo. J Neurosci 1998; 18: 1038-1046.
    • (1998) J Neurosci , vol.18 , pp. 1038-1046
    • Klöcker, N.1    Cellerino, A.2    Bähr, M.3
  • 21
    • 0344333441 scopus 로고    scopus 로고
    • Inhibition of CPP32-like proteases rescues axotomized retinal ganglion cells from secondary cell death in viro
    • Kermer P, Klöcker N, Labes M, Bähr M. Inhibition of CPP32-like proteases rescues axotomized retinal ganglion cells from secondary cell death in viro. J Neurosci 1998; 18: 4656-4662.
    • (1998) J Neurosci , vol.18 , pp. 4656-4662
    • Kermer, P.1    Klöcker, N.2    Labes, M.3    Bähr, M.4
  • 22
    • 0029586932 scopus 로고
    • Specific and efficient gene transfer strategy offers new potentialities for the treatment of motor neurone diseases
    • Finiels F et al. Specific and efficient gene transfer strategy offers new potentialities for the treatment of motor neurone diseases. Neuroreport 1995; 6: 2473-2478.
    • (1995) Neuroreport , vol.6 , pp. 2473-2478
    • Finiels, F.1
  • 23
    • 0030997980 scopus 로고    scopus 로고
    • Adenovirus-mediated gene transfer of ciliary neurotrophic factor can prevent photoreceptor degeneration in the retinal degeneration (rd) mouse
    • Cayouette M, Gravel C. Adenovirus-mediated gene transfer of ciliary neurotrophic factor can prevent photoreceptor degeneration in the retinal degeneration (rd) mouse. Hum Gene Ther 1997; 8: 423-430.
    • (1997) Hum Gene Ther , vol.8 , pp. 423-430
    • Cayouette, M.1    Gravel, C.2
  • 24
    • 0029793621 scopus 로고    scopus 로고
    • Apoptotic suppression by baculovirus P35 involves cleavage by and inhibition of a virus-induced CED-3/ICE-like protease
    • Bertin J et al. Apoptotic suppression by baculovirus P35 involves cleavage by and inhibition of a virus-induced CED-3/ICE-like protease. J Virol 1996; 70: 6251-6259.
    • (1996) J Virol , vol.70 , pp. 6251-6259
    • Bertin, J.1
  • 25
    • 0032575309 scopus 로고    scopus 로고
    • Interaction of the baculovirus anti-apoptotic protein p35 with caspases. Specificity, kinetics, and characterization of the caspase/p35 complex
    • Zhou Q et al. Interaction of the baculovirus anti-apoptotic protein p35 with caspases. Specificity, kinetics, and characterization of the caspase/p35 complex. Biochemistry 1998; 37: 10757-10765.
    • (1998) Biochemistry , vol.37 , pp. 10757-10765
    • Zhou, Q.1
  • 26
    • 0030977847 scopus 로고    scopus 로고
    • Target protease specificity of the viral serpin CrmA. Analysis of five caspases
    • Zhou Q et al. Target protease specificity of the viral serpin CrmA. Analysis of five caspases. J Biol Chem 1997; 272: 7797-7800.
    • (1997) J Biol Chem , vol.272 , pp. 7797-7800
    • Zhou, Q.1
  • 27
    • 0030860068 scopus 로고    scopus 로고
    • Comparison of the human versus murine cytomegalovirus immediate early gene promoters for transgene expression by adenoviral vectors
    • Addison CL, Hitt M, Kunsken D, Graham FL. Comparison of the human versus murine cytomegalovirus immediate early gene promoters for transgene expression by adenoviral vectors. J Gen Virol 1997; 7: 1653-1661.
    • (1997) J Gen Virol , vol.7 , pp. 1653-1661
    • Addison, C.L.1    Hitt, M.2    Kunsken, D.3    Graham, F.L.4
  • 28
    • 0030795798 scopus 로고    scopus 로고
    • Intrastriatal injection of an adenoviral vector expressing glial-cell-line-derived neurotrophic factor prevents dopaminergic neuron degeneration and behavioral impairment in a rat model of Parkinson disease
    • Bilang-Bleuel A et al. Intrastriatal injection of an adenoviral vector expressing glial-cell-line-derived neurotrophic factor prevents dopaminergic neuron degeneration and behavioral impairment in a rat model of Parkinson disease. Proc Natl Acad Sci USA 1997; 94: 8818-8823.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 8818-8823
    • Bilang-Bleuel, A.1
  • 29
    • 0031019795 scopus 로고    scopus 로고
    • Dopaminergic neurons protected from degeneration by GDNF gene therapy
    • Choi-Lundberg DL et al. Dopaminergic neurons protected from degeneration by GDNF gene therapy. Science 1997; 275: 838-841.
    • (1997) Science , vol.275 , pp. 838-841
    • Choi-Lundberg, D.L.1
  • 30
    • 1842329729 scopus 로고    scopus 로고
    • Adenoviral gene transfer of ciliary neurotrophic factor and brain-derived neurotrophic factor leads to long-term survival of axotomized motor neurons
    • Gravel C, Gotz R, Lorrain A, Sendtner M. Adenoviral gene transfer of ciliary neurotrophic factor and brain-derived neurotrophic factor leads to long-term survival of axotomized motor neurons. Nature Med 1997; 3: 765-770.
    • (1997) Nature Med , vol.3 , pp. 765-770
    • Gravel, C.1    Gotz, R.2    Lorrain, A.3    Sendtner, M.4
  • 31
    • 0032584228 scopus 로고    scopus 로고
    • Prolonged delivery of brain-derived neurotrophic factor by adenovirus-infected muller cells temporarily rescues injured retinal ganglion cells
    • Di-Polo A et al. Prolonged delivery of brain-derived neurotrophic factor by adenovirus-infected Muller cells temporarily rescues injured retinal ganglion cells. Proc Natl Acad Sci USA 1998; 95: 3978-3983.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 3978-3983
    • Di-Polo, A.1
  • 32
    • 0030025668 scopus 로고    scopus 로고
    • Overexpression of Bcl-2 with herpes simplex virus vectors protects CNS neurons against neurological insults in vitro and in vivo
    • Lawrence MS et al. Overexpression of Bcl-2 with herpes simplex virus vectors protects CNS neurons against neurological insults in vitro and in vivo. J Neurosci 1996; 16: 486-496.
    • (1996) J Neurosci , vol.16 , pp. 486-496
    • Lawrence, M.S.1
  • 33
    • 0030848529 scopus 로고    scopus 로고
    • Elevation of neuronal expression of NAIP reduces ischemic damage in the rat hippocampus
    • Xu DG et al. Elevation of neuronal expression of NAIP reduces ischemic damage in the rat hippocampus. Nature Med 1997; 3: 997-1004.
    • (1997) Nature Med , vol.3 , pp. 997-1004
    • Xu, D.G.1
  • 34
    • 0025299379 scopus 로고
    • Immune privilege and immune regulation in the eye
    • Niederkorn JY. Immune privilege and immune regulation in the eye. Adv Immunol 1990; 48: 191-226.
    • (1990) Adv Immunol , vol.48 , pp. 191-226
    • Niederkorn, J.Y.1
  • 35
    • 0032575750 scopus 로고    scopus 로고
    • Caspases: Enemies within
    • Thornberry NA, Lazebnik Y. Caspases: enemies within. Science 1998; 281: 1312-1316.
    • (1998) Science , vol.281 , pp. 1312-1316
    • Thornberry, N.A.1    Lazebnik, Y.2
  • 36
    • 0345286587 scopus 로고    scopus 로고
    • CPP-32 like proteases are major mediators of apoptosis in axotomized retinal ganglion cells in vivo
    • Abstr.
    • Kermer P et al. CPP-32 like proteases are major mediators of apoptosis in axotomized retinal ganglion cells in vivo. Soc Neurosci 1998; 24: 614.13 (Abstr.).
    • (1998) Soc Neurosci , vol.24 , pp. 61413
    • Kermer, P.1
  • 37
    • 0030715323 scopus 로고    scopus 로고
    • Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade
    • Li P et al. Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell 1997; 91: 479-489.
    • (1997) Cell , vol.91 , pp. 479-489
    • Li, P.1
  • 38
    • 0032502855 scopus 로고    scopus 로고
    • Activation of caspases triggered by cytochrome c in vitro
    • Pan G, Humke EW, Dixit VM. Activation of caspases triggered by cytochrome c in vitro. FEBS Lett 1998; 426: 151-154.
    • (1998) FEBS Lett , vol.426 , pp. 151-154
    • Pan, G.1    Humke, E.W.2    Dixit, V.M.3
  • 39
    • 0029760296 scopus 로고    scopus 로고
    • Role of T cells in inflammation caused by adenovirus vectors in the brain
    • Byrnes AP, Wood MJ, Charlton HM. Role of T cells in inflammation caused by adenovirus vectors in the brain. Gene Therapy 1996; 3: 644-651.
    • (1996) Gene Therapy , vol.3 , pp. 644-651
    • Byrnes, A.P.1    Wood, M.J.2    Charlton, H.M.3
  • 40
    • 0029876694 scopus 로고    scopus 로고
    • Immunological instability of persistent adenovirus vectors in the brain: Peripheral exposure to vector leads to renewed inflammation, reduced gene expression, and demyelination
    • Byrnes AP, MacLaren RE, Charlton HM. Immunological instability of persistent adenovirus vectors in the brain: peripheral exposure to vector leads to renewed inflammation, reduced gene expression, and demyelination. J Neurosci 1996; 16: 3045-3055.
    • (1996) J Neurosci , vol.16 , pp. 3045-3055
    • Byrnes, A.P.1    MacLaren, R.E.2    Charlton, H.M.3
  • 41
    • 0030840092 scopus 로고    scopus 로고
    • Ex vivo adenovirus-mediated gene transfer and immunomodulatory protein production in human cornea
    • Oral HB et al. Ex vivo adenovirus-mediated gene transfer and immunomodulatory protein production in human cornea. Gene Therapy 1997; 4: 639-647.
    • (1997) Gene Therapy , vol.4 , pp. 639-647
    • Oral, H.B.1
  • 42
    • 0025976935 scopus 로고
    • Genetically modified skin fibroblasts persist long after transplantation but gradually inactivate introduced genes
    • Palmer TD, Rosman GJ, Osborne WR, Miller AD. Genetically modified skin fibroblasts persist long after transplantation but gradually inactivate introduced genes. Proc Natl Acad Sci USA 1991; 88: 1330-1334.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 1330-1334
    • Palmer, T.D.1    Rosman, G.J.2    Osborne, W.R.3    Miller, A.D.4
  • 44
    • 0020586401 scopus 로고
    • Adenovirus fiber protein produces synthesis of interferon in mouse spleen and macrophage cultures
    • Tiensiwakul P, Khoobyarian N. Adenovirus fiber protein produces synthesis of interferon in mouse spleen and macrophage cultures. Intervirology 1983; 20: 52-55.
    • (1983) Intervirology , vol.20 , pp. 52-55
    • Tiensiwakul, P.1    Khoobyarian, N.2
  • 45
    • 0023883901 scopus 로고
    • Transcription of interferon-stimulated genes is induced by adenovirus particles but is suppressed by E1A gene products
    • Reich N, Pine R, Levy D, Darnell JE Jr. Transcription of interferon-stimulated genes is induced by adenovirus particles but is suppressed by E1A gene products. J Virol 1988; 62: 114-119.
    • (1988) J Virol , vol.62 , pp. 114-119
    • Reich, N.1    Pine, R.2    Levy, D.3    Darnell J.E., Jr.4
  • 46
    • 0028842611 scopus 로고
    • Interferon-gamma inhibits transgene expression driven by SV40 or CMV promoters but augments expression driven by the mammalian MHC1 promoter
    • Harms JS, Splitter GA. Interferon-gamma inhibits transgene expression driven by SV40 or CMV promoters but augments expression driven by the mammalian MHC1 promoter. Hum Gene Ther 1995; 6: 1291-1297.
    • (1995) Hum Gene Ther , vol.6 , pp. 1291-1297
    • Harms, J.S.1    Splitter, G.A.2
  • 47
    • 0029763396 scopus 로고    scopus 로고
    • Adenovirus-mediated gene transfer to retinal ganglion cells
    • Cayouette M, Gravel C. Adenovirus-mediated gene transfer to retinal ganglion cells. Inv Opthal Vis Sci 1996; 37: 2022-2028.
    • (1996) Inv Opthal Vis Sci , vol.37 , pp. 2022-2028
    • Cayouette, M.1    Gravel, C.2
  • 48
    • 0028559768 scopus 로고
    • An efficient and flexible system for construction of adenovirus vectors with insertions or deletions in early regions 1 and 3
    • Bett AJ, Haddara W, Prevec L, Graham FL. An efficient and flexible system for construction of adenovirus vectors with insertions or deletions in early regions 1 and 3. Proc Natl Acad Sci USA 1994; 91: 8802-8806.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 8802-8806
    • Bett, A.J.1    Haddara, W.2    Prevec, L.3    Graham, F.L.4
  • 49
    • 0029981799 scopus 로고    scopus 로고
    • Supernatant rescue assay vs. polymerase chain reaction for detection of wild type adenovirus-contaminating recombinant adenovirus stocks
    • Dion LD, Fang J, Garver RI Jr. Supernatant rescue assay vs. polymerase chain reaction for detection of wild type adenovirus-contaminating recombinant adenovirus stocks. J Virol Meth 1996; 56: 99-107.
    • (1996) J Virol Meth , vol.56 , pp. 99-107
    • Dion, L.D.1    Fang, J.2    Garver R.I., Jr.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.