-
1
-
-
0025811297
-
Control of embryonic motor neuron survival in vivo by ciliary neurotrophic factor
-
Oppenheim, R.W., Prevette, D., Qin-Wei, Y., Collins, F. & MacDonald J. Control of embryonic motor neuron survival in vivo by ciliary neurotrophic factor. Science 251, 1616-1618 (1991).
-
(1991)
Science
, vol.251
, pp. 1616-1618
-
-
Oppenheim, R.W.1
Prevette, D.2
Qin-Wei, Y.3
Collins, F.4
MacDonald, J.5
-
2
-
-
0027094145
-
Brain-derived neurotrophic factor rescues developing avian motor neurons from cell death
-
Oppenheim, R.W., Qin-Wei, Y., Prevette, D. & Yan, Q. Brain-derived neurotrophic factor rescues developing avian motor neurons from cell death. Nature 360, 755-757 (1992).
-
(1992)
Nature
, vol.360
, pp. 755-757
-
-
Oppenheim, R.W.1
Qin-Wei, Y.2
Prevette, D.3
Yan, Q.4
-
3
-
-
0025325548
-
Ciliary neurotrophic factor prevents the degeneration of motor neurons after axotomy
-
Sendtner, M., Kreutzberg, C.W. & Thoenen, H. Ciliary neurotrophic factor prevents the degeneration of motor neurons after axotomy. Nature 345, 440-441 (1990)
-
(1990)
Nature
, vol.345
, pp. 440-441
-
-
Sendtner, M.1
Kreutzberg, C.W.2
Thoenen, H.3
-
4
-
-
0027070473
-
Brain-derived neurotrophic factor prevents the death of motor neurons in newborn rats after nerve section
-
Sendtner, M., Holtmann, B., Kolbeck, R., Thoenen, H. & Barde, Y.-A. Brain-derived neurotrophic factor prevents the death of motor neurons in newborn rats after nerve section. Nature 360, 757-758 (1992).
-
(1992)
Nature
, vol.360
, pp. 757-758
-
-
Sendtner, M.1
Holtmann, B.2
Kolbeck, R.3
Thoenen, H.4
Barde, Y.-A.5
-
5
-
-
0028058774
-
BDNF and NT-3 rescue sensory but not motoneurones following axotomy in the neonate
-
Eriksson, N.P., Lindsay, R.M. & Aldskogius, H. BDNF and NT-3 rescue sensory but not motoneurones following axotomy in the neonate. Neuroreport 5, 1445-1448 (1994).
-
(1994)
Neuroreport
, vol.5
, pp. 1445-1448
-
-
Eriksson, N.P.1
Lindsay, R.M.2
Aldskogius, H.3
-
6
-
-
0028890986
-
Quantitative comparison of the transient rescue effects of neurotrophic factors on axotomized motor neurons in vivo
-
Vejsada, R., Sagot, Y. & Kato, A.C. Quantitative comparison of the transient rescue effects of neurotrophic factors on axotomized motor neurons in vivo. Eur. J. Neurosci. 7, 108-115 (1995).
-
(1995)
Eur. J. Neurosci.
, vol.7
, pp. 108-115
-
-
Vejsada, R.1
Sagot, Y.2
Kato, A.C.3
-
7
-
-
0026694239
-
Synthesis and location of ciliary neurotrophic factor in the rat sciatic nerve of the adult rat after lesion and during regeneration
-
Sendtner, M., Stöckli, K.A. & Thoenen, H. Synthesis and location of ciliary neurotrophic factor in the rat sciatic nerve of the adult rat after lesion and during regeneration. J. Cell Biol. 118, 139-148 (1992).
-
(1992)
J. Cell Biol.
, vol.118
, pp. 139-148
-
-
Sendtner, M.1
Stöckli, K.A.2
Thoenen, H.3
-
8
-
-
0026768108
-
Enhanced synthesis of brain-derived neurotrophic factor in the lesioned peripheral nerve: Different mechanisms are responsible for the regulation of BDNF and NGF mRNA
-
Meyer, M., Matsuoka, I., Wetmore, C., Olson, L. & Thoenen, H. Enhanced synthesis of brain-derived neurotrophic factor in the lesioned peripheral nerve: Different mechanisms are responsible for the regulation of BDNF and NGF mRNA. J. Cell Biol. 119, 45-54 (1992).
-
(1992)
J. Cell Biol.
, vol.119
, pp. 45-54
-
-
Meyer, M.1
Matsuoka, I.2
Wetmore, C.3
Olson, L.4
Thoenen, H.5
-
9
-
-
0030953519
-
Gene therapy of murine motor neuron disease using adenoviral vectors for neurotrophic factors
-
Haase, G. et al. Gene therapy of murine motor neuron disease using adenoviral vectors for neurotrophic factors. Nature Med. 3, 429-436 (1997).
-
(1997)
Nature Med.
, vol.3
, pp. 429-436
-
-
Haase, G.1
-
10
-
-
0022354769
-
Naturally occurring cell death during neural development
-
Oppenheim, R.W. Naturally occurring cell death during neural development. Trends Neurosci. 8, 487-493 (1985).
-
(1985)
Trends Neurosci.
, vol.8
, pp. 487-493
-
-
Oppenheim, R.W.1
-
11
-
-
0027374952
-
Influences of neurotrophins on mammalian motor neurons in vivo
-
Yan, Q. et al. Influences of neurotrophins on mammalian motor neurons in vivo. J. Neurobiol. 24, 1555-1577 (1993).
-
(1993)
J. Neurobiol.
, vol.24
, pp. 1555-1577
-
-
Yan, Q.1
-
12
-
-
0003382802
-
Pathology of motor neurons with special reference to amyotrophic lateral sclerosis and related diseases
-
eds. Tsubaki, T. & Toyokura, Y. University Park Press, Baltimore
-
Hirano, A. & Iwata, M. Pathology of motor neurons with special reference to amyotrophic lateral sclerosis and related diseases, in: Amyotrophic Lateral Sclerosis. (eds. Tsubaki, T. & Toyokura, Y.) 107-134 (University Park Press, Baltimore, 1979).
-
(1979)
Amyotrophic Lateral Sclerosis
, pp. 107-134
-
-
Hirano, A.1
Iwata, M.2
-
13
-
-
0021604040
-
Motor neuron death after sciatic nerve section in newborn rats
-
Schmalbruch, H. Motor neuron death after sciatic nerve section in newborn rats. J. Comp. Neurol. 224, 252-258 (1984).
-
(1984)
J. Comp. Neurol.
, vol.224
, pp. 252-258
-
-
Schmalbruch, H.1
-
14
-
-
0027131764
-
Members of several gene families influence survival of rat motor neurons in vitro and in vivo
-
Hughes, R.A., Sendtner, M. & Thoenen, H. Members of several gene families influence survival of rat motor neurons in vitro and in vivo. J. Neurosci. Res. 36, 663-671 (1993).
-
(1993)
J. Neurosci. Res.
, vol.36
, pp. 663-671
-
-
Hughes, R.A.1
Sendtner, M.2
Thoenen, H.3
-
15
-
-
0028109717
-
GDNF: A potent survival factor for motor neurons present in peripheral nerve and muscle
-
Henderson, C.E. et al. GDNF: A potent survival factor for motor neurons present in peripheral nerve and muscle. Science 266, 1062-1064 (1994).
-
(1994)
Science
, vol.266
, pp. 1062-1064
-
-
Henderson, C.E.1
-
16
-
-
0027067035
-
Brain-derived neurotrophic factor rescues spinal motor neurons from axotomy-induced cell death
-
Yan, Q., Elliott, J. & Snider, W.D. Brain-derived neurotrophic factor rescues spinal motor neurons from axotomy-induced cell death. Nature 360, 753-755 (1992).
-
(1992)
Nature
, vol.360
, pp. 753-755
-
-
Yan, Q.1
Elliott, J.2
Snider, W.D.3
-
17
-
-
0028261401
-
Neurotrophin 4/5 is a trophic factor for mammalian facial motor neurons
-
Koliatsos, V.E. et al. Neurotrophin 4/5 is a trophic factor for mammalian facial motor neurons. Proc. Natl. Acad. Sci. USA 91, 3304-3308 (1994).
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 3304-3308
-
-
Koliatsos, V.E.1
-
18
-
-
0028854836
-
In vivo neurotrophic effects of GDNF on neonatal and adult facial motor neurons
-
Yan, Q., Matheson, C. & Lopez, O.T. In vivo neurotrophic effects of GDNF on neonatal and adult facial motor neurons. Nature 373, 341-344 (1995).
-
(1995)
Nature
, vol.373
, pp. 341-344
-
-
Yan, Q.1
Matheson, C.2
Lopez, O.T.3
-
19
-
-
0026550179
-
Cholinergic differentiation factor (CDF/LIF) promotes survival of isolated rat embryonic motor neurons in vitro
-
Martinou, J.C, Martinou, I. & Kato, A. Cholinergic differentiation factor (CDF/LIF) promotes survival of isolated rat embryonic motor neurons in vitro. Neuron 8, 737-744 (1992).
-
(1992)
Neuron
, vol.8
, pp. 737-744
-
-
Martinou, J.C.1
Martinou, I.2
Kato, A.3
-
20
-
-
0026749255
-
Ciliary neurotrophic factor prevents degeneration of motor neurons in mouse mutant progressive motor neuronopathy
-
Sendtner, M. et al. Ciliary neurotrophic factor prevents degeneration of motor neurons in mouse mutant progressive motor neuronopathy. Nature 358, 502-504 (1992).
-
(1992)
Nature
, vol.358
, pp. 502-504
-
-
Sendtner, M.1
-
21
-
-
0028916844
-
Effects of brain-derived neurotrophic factor on motor dysfunction in wobbler mouse motor neuron disease
-
Ikeda, K. et al. Effects of brain-derived neurotrophic factor on motor dysfunction in wobbler mouse motor neuron disease. Ann. Neurol. 37, 505-511 (1995).
-
(1995)
Ann. Neurol.
, vol.37
, pp. 505-511
-
-
Ikeda, K.1
-
22
-
-
0028095440
-
The effects of ciliary neurotrophic factor on motor neuron dysfunction in wobbler mouse motor neuron disease
-
Mitsumoto, H. et al. The effects of ciliary neurotrophic factor on motor neuron dysfunction in wobbler mouse motor neuron disease. Ann. Neurol. 36, 142-148 (1994).
-
(1994)
Ann. Neurol.
, vol.36
, pp. 142-148
-
-
Mitsumoto, H.1
-
23
-
-
0028027060
-
Arrest of motor neuron disease in wobbler mice cotreated with CNTF and BDNF
-
Mitsumoto. H, et al. Arrest of motor neuron disease in wobbler mice cotreated with CNTF and BDNF. Science 265, 1107-1110 (1994).
-
(1994)
Science
, vol.265
, pp. 1107-1110
-
-
Mitsumoto, H.1
-
24
-
-
9044219848
-
A placebo-controlled trial of recombinant human ciliary neurotrophic (rhCNTF) factor in amyotrophic lateral sclerosis
-
Miller, R.G. et al. A placebo-controlled trial of recombinant human ciliary neurotrophic (rhCNTF) factor in amyotrophic lateral sclerosis. Ann. Neurol. 39, 256-260 (1996).
-
(1996)
Ann. Neurol.
, vol.39
, pp. 256-260
-
-
Miller, R.G.1
-
25
-
-
0028137577
-
Ciliary neurotrophic factor: Pharmacokinetics and acute phase response
-
Dittrich, F., Thoenen, H. & Sendtner, M. Ciliary neurotrophic factor: Pharmacokinetics and acute phase response. Ann. Neurol. 35, 151-163 (1994).
-
(1994)
Ann. Neurol.
, vol.35
, pp. 151-163
-
-
Dittrich, F.1
Thoenen, H.2
Sendtner, M.3
-
26
-
-
0028863291
-
The pharmacokinetics of subcutaneously administered recombinant human ciliary neurotrophic factor (rHCNTF) in patients with amyotrophic lateral sclerosis
-
ALS CNTF Treatment Study (ACTS) Phase I-II Group. The pharmacokinetics of subcutaneously administered recombinant human ciliary neurotrophic factor (rHCNTF) in patients with amyotrophic lateral sclerosis. Clin. Neuropharmacol. 18, 500-518 (1995).
-
(1995)
Clin. Neuropharmacol.
, vol.18
, pp. 500-518
-
-
-
27
-
-
0027936521
-
BDNF-mediated rescue of axotomized motor neurones decreases with increasing dose
-
Vejsada, R., Sagot, Y. & Kato, A.C. BDNF-mediated rescue of axotomized motor neurones decreases with increasing dose. Neuroreport 5, 1889-1892 (1994).
-
(1994)
Neuroreport
, vol.5
, pp. 1889-1892
-
-
Vejsada, R.1
Sagot, Y.2
Kato, A.C.3
-
28
-
-
0028982268
-
Differential regulation of p21ras activation in neurons by nerve growth factor and brain-derived neurotrophic factor
-
Carter, B.D., Zirrgiebel, U. & Barde, Y.A. Differential regulation of p21ras activation in neurons by nerve growth factor and brain-derived neurotrophic factor. J. Biol. Chem. 270, 21751-21757 (1995).
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 21751-21757
-
-
Carter, B.D.1
Zirrgiebel, U.2
Barde, Y.A.3
-
29
-
-
0027969192
-
The biological responses of axotomized adult motor neurons to brain-derived neurotrophic factor
-
Yan, Q., Matheson, C., Lopez, O.T. & Miller, J.A. The biological responses of axotomized adult motor neurons to brain-derived neurotrophic factor. J. Neurosci. 14, 5281-5291 (1994).
-
(1994)
J. Neurosci.
, vol.14
, pp. 5281-5291
-
-
Yan, Q.1
Matheson, C.2
Lopez, O.T.3
Miller, J.A.4
-
30
-
-
0007101117
-
Pharmacokinetics of intrathecally applied BDNF and effects on spinal motor neurons
-
Dittrich, F. et al. Pharmacokinetics of intrathecally applied BDNF and effects on spinal motor neurons. Exp. Neurol. 141, 225-239 (1996).
-
(1996)
Exp. Neurol.
, vol.141
, pp. 225-239
-
-
Dittrich, F.1
-
31
-
-
0024805216
-
Molecular cloning, expression and regional distribution of rat ciliary neurotrophic factor
-
Stöckli, K.A. et al. Molecular cloning, expression and regional distribution of rat ciliary neurotrophic factor. Nature 342, 920-923 (1989).
-
(1989)
Nature
, vol.342
, pp. 920-923
-
-
Stöckli, K.A.1
-
32
-
-
0025983810
-
Regional distribution, developmental changes and cellular localization of CNTF-mRNA and protein in the rat brain
-
Stöckli, K.A. et al. Regional distribution, developmental changes and cellular localization of CNTF-mRNA and protein in the rat brain. J. Cell Biol. 115, 447-459 (1991).
-
(1991)
J. Cell Biol.
, vol.115
, pp. 447-459
-
-
Stöckli, K.A.1
-
33
-
-
0029077018
-
Polymer encapsulated cell lines genetically engineered to release ciliary neurotrophic factor can slow down progressive motor neuronopathy in the mouse
-
Sagot, Y. et al. Polymer encapsulated cell lines genetically engineered to release ciliary neurotrophic factor can slow down progressive motor neuronopathy in the mouse. Eur. J. Neurosci. 7, 1313-1322 (1995).
-
(1995)
Eur. J. Neurosci.
, vol.7
, pp. 1313-1322
-
-
Sagot, Y.1
-
34
-
-
0018581742
-
Isolation of adenovirus type 5 host range deletion mutants defective for transformation of rat embryo cells
-
Jones, N. & Schenk, T. Isolation of adenovirus type 5 host range deletion mutants defective for transformation of rat embryo cells. Cell 17, 683-689 (1979).
-
(1979)
Cell
, vol.17
, pp. 683-689
-
-
Jones, N.1
Schenk, T.2
-
35
-
-
0028807696
-
FK 506 immunosuppression to control the immune reactions triggered by first-generation adenovirus-mediated gene transfer
-
Vilquin, J.-T. et al. FK 506 immunosuppression to control the immune reactions triggered by first-generation adenovirus-mediated gene transfer. Hum. Gene Ther. 6, 1391-1401 (1995).
-
(1995)
Hum. Gene Ther.
, vol.6
, pp. 1391-1401
-
-
Vilquin, J.-T.1
-
36
-
-
0027484249
-
Disruption of the CNTF gene results in motor neuron degeneration
-
Masu, Y. et al. Disruption of the CNTF gene results in motor neuron degeneration. Nature 365, 27-32 (1993).
-
(1993)
Nature
, vol.365
, pp. 27-32
-
-
Masu, Y.1
-
37
-
-
0027457561
-
An adenovirus vector for gene transfer into neurons and glia in the brain
-
Le Gal La Salle, G. et al. An adenovirus vector for gene transfer into neurons and glia in the brain. Science 259, 988-990 (1993).
-
(1993)
Science
, vol.259
, pp. 988-990
-
-
Le Gal La Salle, G.1
-
38
-
-
0027408530
-
Transfer of a foreign gene into the brain using adenovirus vectors
-
Akli, S. et al. Transfer of a foreign gene into the brain using adenovirus vectors. Nature Genet. 3, 224-228 (1993).
-
(1993)
Nature Genet.
, vol.3
, pp. 224-228
-
-
Akli, S.1
-
39
-
-
0026782439
-
Widespread long-term gene transfer to mouse skeletal muscles and heart
-
Stratford-Perricaudet, L.D., Makeh, I., Perricaudet, M. & Briand, P. Widespread long-term gene transfer to mouse skeletal muscles and heart. J. Clin. Invest. 90, 626-630 (1992).
-
(1992)
J. Clin. Invest.
, vol.90
, pp. 626-630
-
-
Stratford-Perricaudet, L.D.1
Makeh, I.2
Perricaudet, M.3
Briand, P.4
-
40
-
-
0029936764
-
Immune responses to transgene-encoded proteins limit the stability of gene expression after injection of replication-defective adenovirus vectors
-
Tripathy, K.S., Hugh, B.B., Goldwasser, E. & and Leiden J.M. Immune responses to transgene-encoded proteins limit the stability of gene expression after injection of replication-defective adenovirus vectors. Nature Med. 2, 545-550 (1996).
-
(1996)
Nature Med.
, vol.2
, pp. 545-550
-
-
Tripathy, K.S.1
Hugh, B.B.2
Goldwasser, E.3
Leiden, J.M.4
|