Increased mitochondrial superoxide production in rat liver mitochondria, rat hepatocytes, and HepG2 cells following ethinyl estradiol treatment

Toxicological Sciences

Volumn 51, Issue 2, 1999, Pages 224-235

  Chen, Jinqiang ^a   Li, Yunbo ^a   Lavigne, Jackie A ^a   Trush, Michael A ^a   Yager, James D ^a  

^a JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

Ethinyl estradiol; Hepatic promoters; Liver; Mitosuppression; Rat; Superoxide

Indexed keywords

ANTIESTROGEN; CATECHOL DERIVATIVE; CATECHOL METHYLTRANSFERASE; CYTOCHROME P450; ESTRADIOL; ESTROGEN; ESTROGEN RECEPTOR; ETHINYLESTRADIOL; GLUTATHIONE; GLUTATHIONE ETHYL ESTER; ICI 182708; LUCIGENIN; SUPEROXIDE; TUMOR PROMOTER; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL GROWTH; CELL STRAIN HEPG2; CHEMOLUMINESCENCE; CONTROLLED STUDY; ESTROGEN METABOLISM; FEMALE; LIVER CARCINOGENESIS; LIVER CELL; LIVER MITOCHONDRION; MALE; NONHUMAN; RAT; RESPIRATORY CHAIN;

ANIMALS; CARCINOMA, HEPATOCELLULAR; CATECHOL O-METHYLTRANSFERASE; CELLS, CULTURED; ESTRADIOL; ESTRADIOL CONGENERS; ESTROGEN RECEPTOR MODULATORS; ETHINYL ESTRADIOL; GLUTATHIONE; LIVER; LIVER NEOPLASMS; MALE; MITOCHONDRIA, LIVER; RATS; RATS, INBRED F344; SUPEROXIDES; TUMOR CELLS, CULTURED;

ANIMALIA;

EID: 0032699638     PISSN: 10966080     EISSN: None     Source Type: Journal    
DOI: 10.1093/toxsci/51.2.224     Document Type: Article

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