메뉴 건너뛰기




Volumn 14, Issue 5, 2003, Pages 228-235

Estrogen and ischemic neuroprotection: An integrated view

Author keywords

[No Author keywords available]

Indexed keywords

ESTRADIOL; ESTROGEN;

EID: 0038268485     PISSN: 10432760     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1043-2760(03)00076-6     Document Type: Review
Times cited : (281)

References (83)
  • 1
    • 0035950682 scopus 로고    scopus 로고
    • A clinical trial of estrogen-replacement therapy after ischemic stroke
    • Viscoli, C.M. et al. (2001) A clinical trial of estrogen-replacement therapy after ischemic stroke. N. Engl. J. Med. 345, 1243-1249
    • (2001) N. Engl. J. Med. , vol.345 , pp. 1243-1249
    • Viscoli, C.M.1
  • 2
    • 0037125379 scopus 로고    scopus 로고
    • Risks and benefits of estrogen plus progestin in healthy postmenopausal women: Principal results from the women's health initiative randomized controlled trial
    • Rossouw, J.E. et al. (2002) Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results from the women's health initiative randomized controlled trial. J. Am. Med. Assoc. 288, 321-333
    • (2002) J. Am. Med. Assoc. , vol.288 , pp. 321-333
    • Rossouw, J.E.1
  • 3
    • 0017083393 scopus 로고
    • Proceedings: Prophylactic trials for stroke in stroke-prone SHR: Effect of sex hormones
    • Yamori, Y. et al. (1976) Proceedings: prophylactic trials for stroke in stroke-prone SHR: effect of sex hormones. Jpn. Heart J. 17, 404-406
    • (1976) Jpn. Heart J. , vol.17 , pp. 404-406
    • Yamori, Y.1
  • 4
    • 0031984050 scopus 로고    scopus 로고
    • Gender-linked brain injury in experimental stroke
    • Alkayed, N.J. et al. (1998) Gender-linked brain injury in experimental stroke. Stroke 29, 159-165
    • (1998) Stroke , vol.29 , pp. 159-165
    • Alkayed, N.J.1
  • 5
    • 0035125947 scopus 로고    scopus 로고
    • 17-β Estradiol can reduce secondary ischemic damage and mortality of subarachnoid hemorrhage
    • Yang, S.H. et al. (2001) 17-β Estradiol can reduce secondary ischemic damage and mortality of subarachnoid hemorrhage. J. Cereb. Blood Flow Metab. 21, 174-181
    • (2001) J. Cereb. Blood Flow Metab. , vol.21 , pp. 174-181
    • Yang, S.H.1
  • 6
    • 0033981785 scopus 로고    scopus 로고
    • Estrogen receptor antagonist ICI 182, 780 exacerbates ischemic injury in female mouse
    • Sawada, M. et al. (2000) Estrogen receptor antagonist ICI 182, 780 exacerbates ischemic injury in female mouse. J. Cereb. Blood Flow Metab. 20, 112-118
    • (2000) J. Cereb. Blood Flow Metab. , vol.20 , pp. 112-118
    • Sawada, M.1
  • 7
    • 0033976986 scopus 로고    scopus 로고
    • Neuroprotective effects of female gonadal steroids in reproductively senescent female rats
    • Alkayed, N.J. et al. (2000) Neuroprotective effects of female gonadal steroids in reproductively senescent female rats. Stroke 31, 161-168
    • (2000) Stroke , vol.31 , pp. 161-168
    • Alkayed, N.J.1
  • 8
  • 9
    • 0033956280 scopus 로고    scopus 로고
    • Estrogen status affects sensitivity to focal cerebral ischemia in stroke-prone spontaneously hypertensive rats
    • Carswell, H.V. et al. (2000) Estrogen status affects sensitivity to focal cerebral ischemia in stroke-prone spontaneously hypertensive rats. Am. J. Physiol. Heart Circ. Physiol. 278, H290-H294
    • (2000) Am. J. Physiol. Heart Circ. Physiol. , vol.278
    • Carswell, H.V.1
  • 10
    • 0033755647 scopus 로고    scopus 로고
    • Estrogen decreases infarct size after temporary focal ischemia in a genetic model of type 1 diabetes mellitus
    • Toung, T.K. et al. (2000) Estrogen decreases infarct size after temporary focal ischemia in a genetic model of type 1 diabetes mellitus. Stroke 31, 2701-2706
    • (2000) Stroke , vol.31 , pp. 2701-2706
    • Toung, T.K.1
  • 11
    • 0031738820 scopus 로고    scopus 로고
    • Estradiol protects against ischemic injury
    • Dubal, D.B. et al. (1998) Estradiol protects against ischemic injury. J. Cereb. Blood Flow Metab. 18, 1253-1258
    • (1998) J. Cereb. Blood Flow Metab. , vol.18 , pp. 1253-1258
    • Dubal, D.B.1
  • 12
    • 0035910642 scopus 로고    scopus 로고
    • Association of serum estrogen level and ischemic neuroprotection in female rats
    • Liao, S. et al. (2001) Association of serum estrogen level and ischemic neuroprotection in female rats. Neurosci. Lett. 297, 159-162
    • (2001) Neurosci. Lett. , vol.297 , pp. 159-162
    • Liao, S.1
  • 13
    • 0032587611 scopus 로고    scopus 로고
    • 17β-Estradiol reduces stroke injury in estrogen-deficient female animals
    • Rusa, R. et al. (1999) 17β-Estradiol reduces stroke injury in estrogen-deficient female animals. Stroke 30, 1665-1670
    • (1999) Stroke , vol.30 , pp. 1665-1670
    • Rusa, R.1
  • 14
    • 0034018107 scopus 로고    scopus 로고
    • Estradiol exerts neuroprotective effects when administered after ischemic insult
    • Yang, S.H. et al. (2000) Estradiol exerts neuroprotective effects when administered after ischemic insult. Stroke 31, 745-749
    • (2000) Stroke , vol.31 , pp. 745-749
    • Yang, S.H.1
  • 15
    • 0034745252 scopus 로고    scopus 로고
    • Postischemic estrogen reduces hypoperfusion and secondary ischemia after experimental stroke
    • McCullough, L.D. et al. (2001) Postischemic estrogen reduces hypoperfusion and secondary ischemia after experimental stroke. Stroke 32, 796-802
    • (2001) Stroke , vol.32 , pp. 796-802
    • McCullough, L.D.1
  • 16
    • 0035805173 scopus 로고    scopus 로고
    • Deleterious effect of β-estradiol in a rat model of transient forebrain ischemia
    • Harukuni, I. et al. (2001) Deleterious effect of β-estradiol in a rat model of transient forebrain ischemia. Brain Res. 900, 137-142
    • (2001) Brain Res. , vol.900 , pp. 137-142
    • Harukuni, I.1
  • 17
    • 0032589256 scopus 로고    scopus 로고
    • 17βEstradiol enhances NMDA receptor-mediated EPSPs and long-term potentiation
    • Foy, M.R. et al. (1999) 17βEstradiol enhances NMDA receptor-mediated EPSPs and long-term potentiation. J. Neurophysiol. 81, 925-929
    • (1999) J. Neurophysiol. , vol.81 , pp. 925-929
    • Foy, M.R.1
  • 18
    • 0023628759 scopus 로고
    • Structural organization and expression of the mouse estrogen receptor
    • White, R. et al. (1987) Structural organization and expression of the mouse estrogen receptor. Mol. Endocrinol. 1, 735-744
    • (1987) Mol. Endocrinol. , vol.1 , pp. 735-744
    • White, R.1
  • 19
    • 0030579801 scopus 로고    scopus 로고
    • Cloning of a novel receptor expressed in rat prostate and ovary
    • Kuiper, G.G. et al. (1996) Cloning of a novel receptor expressed in rat prostate and ovary. Proc. Natl. Acad. Sci. U S A 93, 5925-5930
    • (1996) Proc. Natl. Acad. Sci. U. S. A. , vol.93 , pp. 5925-5930
    • Kuiper, G.G.1
  • 20
    • 0030727813 scopus 로고    scopus 로고
    • Comparative distribution of estrogen receptor-α and -β mRNA in the rat central nervous system
    • Shughrue, P.J. et al. (1997) Comparative distribution of estrogen receptor-α and -β mRNA in the rat central nervous system. J. Comp. Neurol. 388, 507-525
    • (1997) J. Comp. Neurol. , vol.388 , pp. 507-525
    • Shughrue, P.J.1
  • 21
    • 0037179117 scopus 로고    scopus 로고
    • Glial expression of estrogen and androgen receptors after rat brain injury
    • Garcia-Ovejero, D. et al. (2002) Glial expression of estrogen and androgen receptors after rat brain injury. J. Comp. Neurol. 450, 256-271
    • (2002) J. Comp. Neurol. , vol.450 , pp. 256-271
    • Garcia-Ovejero, D.1
  • 22
    • 0036780306 scopus 로고    scopus 로고
    • Estrogen action and cytoplasmic signaling cascades. Part I: Membrane-associated signaling complexes
    • Segars, J. and Driggers, P. (2002) Estrogen action and cytoplasmic signaling cascades. Part I: membrane-associated signaling complexes. Trends Endocrinol. Metab. 13, 349-354
    • (2002) Trends Endocrinol. Metab. , vol.13 , pp. 349-354
    • Segars, J.1    Driggers, P.2
  • 23
    • 0036813660 scopus 로고    scopus 로고
    • ER-X: A novel, plasma membrane-associated, putative estrogen receptor that is regulated during development and after ischemic brain injury
    • Toran-Allerand, C.D. et al. (2002) ER-X: a novel, plasma membrane-associated, putative estrogen receptor that is regulated during development and after ischemic brain injury. J. Neurosci. 22, 8391-8401
    • (2002) J. Neurosci. , vol.22 , pp. 8391-8401
    • Toran-Allerand, C.D.1
  • 24
    • 0035834075 scopus 로고    scopus 로고
    • Early membrane estrogenic effects required for full expression of slow genomic actions in a nerve cell line
    • Vasudevan, N. et al. (2001) Early membrane estrogenic effects required for full expression of slow genomic actions in a nerve cell line. Proc. Natl. Acad. Sci. U. S. A. 98, 12267-12271
    • (2001) Proc. Natl. Acad. Sci. U. S. A. , vol.98 , pp. 12267-12271
    • Vasudevan, N.1
  • 25
    • 0036794395 scopus 로고    scopus 로고
    • Signal transducers and activators of transcription as downstream targets of nongenomic estrogen receptor actions
    • Bjornstrom, L. and Sjoberg, M. (2002) Signal transducers and activators of transcription as downstream targets of nongenomic estrogen receptor actions. Mol. Endocrinol. 16, 2202-2214
    • (2002) Mol. Endocrinol. , vol.16 , pp. 2202-2214
    • Bjornstrom, L.1    Sjoberg, M.2
  • 26
    • 0037073672 scopus 로고    scopus 로고
    • Mutations in the estrogen receptor DNA-binding domain may discriminate between the classical mechanism of action and cross-talk with Stat5b and activating protein 1 (AP-1)
    • Bjornstrom, L. and Sjoberg, M. (2002) Mutations in the estrogen receptor DNA-binding domain may discriminate between the classical mechanism of action and cross-talk with Stat5b and activating protein 1 (AP-1). J. Biol. Chem. 277, 48479-48483
    • (2002) J. Biol. Chem. , vol.277 , pp. 48479-48483
    • Bjornstrom, L.1    Sjoberg, M.2
  • 27
    • 0036593191 scopus 로고    scopus 로고
    • Oestrogen as a neuroprotective hormone
    • Behl, C. (2002) Oestrogen as a neuroprotective hormone. Nat. Rev. Neurosci. 3, 433-442
    • (2002) Nat. Rev. Neurosci. , vol.3 , pp. 433-442
    • Behl, C.1
  • 28
    • 0033497678 scopus 로고    scopus 로고
    • Neuroprotection by estrogens in a mouse model of focal cerebral ischemia and in cultured neurons: Evidence for a receptor-independent antioxidative mechanism
    • Culmsee, C. et al. (1999) Neuroprotection by estrogens in a mouse model of focal cerebral ischemia and in cultured neurons: evidence for a receptor-independent antioxidative mechanism. J. Cereb. Blood Flow Metab. 19, 1263-1269
    • (1999) J. Cereb. Blood Flow Metab. , vol.19 , pp. 1263-1269
    • Culmsee, C.1
  • 29
    • 0032563688 scopus 로고    scopus 로고
    • Estrogen-dependent modulation of rat brain ascorbate levels and ischemia-induced ascorbate loss
    • Kume-Kick, J. and Rice, M.E. (1998) Estrogen-dependent modulation of rat brain ascorbate levels and ischemia-induced ascorbate loss. Brain Res. 803, 105-113
    • (1998) Brain Res. , vol.803 , pp. 105-113
    • Kume-Kick, J.1    Rice, M.E.2
  • 30
    • 0036792014 scopus 로고    scopus 로고
    • Estrogen is neuroprotective via an apolipoprotein E-dependent mechanism in a mouse model of global ischemia
    • Horsburgh, K. et al. (2002) Estrogen is neuroprotective via an apolipoprotein E-dependent mechanism in a mouse model of global ischemia. J. Cereb. Blood Flow Metab. 22, 1189-1195
    • (2002) J. Cereb. Blood Flow Metab. , vol.22 , pp. 1189-1195
    • Horsburgh, K.1
  • 31
    • 0037142082 scopus 로고    scopus 로고
    • Protective effects of estrogen on the cardiovascular system
    • Mendelsohn, M.E. (2002) Protective effects of estrogen on the cardiovascular system. Am. J. Cardiol. 89, 12E-17E
    • (2002) Am. J. Cardiol. , vol.89
    • Mendelsohn, M.E.1
  • 32
    • 0033512596 scopus 로고    scopus 로고
    • Estrogen reduces leukocyte adhesion in the cerebral circulation of female rats
    • Santizo, R. and Pelligrino, D.A. (1999) Estrogen reduces leukocyte adhesion in the cerebral circulation of female rats. J. Cereb. Blood Flow Metab. 19, 1061-1065
    • (1999) J. Cereb. Blood Flow Metab. , vol.19 , pp. 1061-1065
    • Santizo, R.1    Pelligrino, D.A.2
  • 33
    • 0035200007 scopus 로고    scopus 로고
    • Role of heme oxygenase-1 in hypoxia-reoxygenation: Requirement of substrate heme to promote cardioprotection
    • Foresti, R. et al. (2001) Role of heme oxygenase-1 in hypoxia-reoxygenation: requirement of substrate heme to promote cardioprotection. Am. J. Physiol. Heart Circ. Physiol. 281, H1976-H1984
    • (2001) Am. J. Physiol. Heart Circ. Physiol. , vol.281
    • Foresti, R.1
  • 34
    • 0344549854 scopus 로고    scopus 로고
    • Nongenomic stimulation of nitric oxide release by estrogen is mediated by estrogen receptor α localized in caveolae
    • Kim, H.P. et al. (1999) Nongenomic stimulation of nitric oxide release by estrogen is mediated by estrogen receptor α localized in caveolae. Biochem. Biophys. Res. Commun. 263, 257-262
    • (1999) Biochem. Biophys. Res. Commun. , vol.263 , pp. 257-262
    • Kim, H.P.1
  • 35
    • 0032589745 scopus 로고    scopus 로고
    • Estrogen receptor α mediates the nongenomic activation of endothelial nitric oxide synthase by estrogen
    • Chen, Z. et al. (1999) Estrogen receptor α mediates the nongenomic activation of endothelial nitric oxide synthase by estrogen. J. Clin. Invest. 103, 401-406
    • (1999) J. Clin. Invest. , vol.103 , pp. 401-406
    • Chen, Z.1
  • 36
    • 0036969044 scopus 로고    scopus 로고
    • 17-β-Oestradiol-induced vasorelaxation in vitro is mediated by eNOS through hsp90 and akt/pkb dependent mechanism
    • Bucci, M. et al. (2002) 17-β-Oestradiol-induced vasorelaxation in vitro is mediated by eNOS through hsp90 and akt/pkb dependent mechanism. Br. J. Pharmacol. 135, 1695-1700
    • (2002) Br. J. Pharmacol. , vol.135 , pp. 1695-1700
    • Bucci, M.1
  • 37
    • 0036798936 scopus 로고    scopus 로고
    • Estrogen modulation of endothelial nitric oxide synthase
    • Chambliss, K.L. and Shaul, P.W. (2002) Estrogen modulation of endothelial nitric oxide synthase. Endocr. Rev. 23, 665-686
    • (2002) Endocr. Rev. , vol.23 , pp. 665-686
    • Chambliss, K.L.1    Shaul, P.W.2
  • 38
    • 0032860804 scopus 로고    scopus 로고
    • Chronic estrogen treatment increases levels of endothelial nitric oxide synthase protein in rat cerebral microvessels
    • McNeill, A.M. et al. (1999) Chronic estrogen treatment increases levels of endothelial nitric oxide synthase protein in rat cerebral microvessels. Stroke 30, 2186-2190
    • (1999) Stroke , vol.30 , pp. 2186-2190
    • McNeill, A.M.1
  • 39
    • 0028964018 scopus 로고
    • Up-regulation of nitric oxide synthase by estradiol in human aortic endothelial cells
    • Hishikawa, K. et al. (1995) Up-regulation of nitric oxide synthase by estradiol in human aortic endothelial cells. FEBS Lett. 360, 291-293
    • (1995) FEBS Lett. , vol.360 , pp. 291-293
    • Hishikawa, K.1
  • 40
    • 0032487513 scopus 로고    scopus 로고
    • Cerebral vasodilating capacity during forebrain ischemia: Effects of chronic estrogen depletion and repletion and the role of neuronal nitric oxide synthase
    • Pelligrino, D.A. et al. (1998) Cerebral vasodilating capacity during forebrain ischemia: effects of chronic estrogen depletion and repletion and the role of neuronal nitric oxide synthase. Neuroreport 9, 3285-3291
    • (1998) Neuroreport , vol.9 , pp. 3285-3291
    • Pelligrino, D.A.1
  • 41
    • 0033004253 scopus 로고    scopus 로고
    • Estrogen provides neuroprotection in transient forebrain ischemia through perfusion-independent mechanisms in rats
    • Wang, Q. et al. (1999) Estrogen provides neuroprotection in transient forebrain ischemia through perfusion-independent mechanisms in rats. Stroke 30, 630-637
    • (1999) Stroke , vol.30 , pp. 630-637
    • Wang, Q.1
  • 42
    • 0036488359 scopus 로고    scopus 로고
    • Effect of estrogen on endothelial function and angiogenesis
    • Rubanyi, G.M. et al. (2002) Effect of estrogen on endothelial function and angiogenesis. Vascul. Pharmacol. 38, 89-98
    • (2002) Vascul. Pharmacol. , vol.38 , pp. 89-98
    • Rubanyi, G.M.1
  • 43
    • 0034076189 scopus 로고    scopus 로고
    • Mechanisms of angiogenesis and arteriogenesis
    • Carmeliet, P. (2000) Mechanisms of angiogenesis and arteriogenesis. Nat. Med. 6, 389-395
    • (2000) Nat. Med. , vol.6 , pp. 389-395
    • Carmeliet, P.1
  • 44
    • 0027936452 scopus 로고
    • Role of angiogenesis in patients with cerebral ischemic stroke
    • Krupinski, J. et al. (1994) Role of angiogenesis in patients with cerebral ischemic stroke. Stroke 25, 1794-1798
    • (1994) Stroke , vol.25 , pp. 1794-1798
    • Krupinski, J.1
  • 45
    • 0037220125 scopus 로고    scopus 로고
    • Role ofestrogen antagonist ICI 182,780 in vessel assembly and apoptosis of endothelial cells
    • Soares, R. et al. (2003) Role ofestrogen antagonist ICI 182,780 in vessel assembly and apoptosis of endothelial cells. Ultrastuct. Pathol. 27, 33-39
    • (2003) Ultrastuct. Pathol. , vol.27 , pp. 33-39
    • Soares, R.1
  • 46
    • 0036072017 scopus 로고    scopus 로고
    • Regulation of endothelial cell survival and apoptosis during angiogenesis
    • Chavakis, E. and Dimmeler, S. (2002) Regulation of endothelial cell survival and apoptosis during angiogenesis. Arterioscler. Thromb. Vasc. Biol. 22, 887-893
    • (2002) Arterioscler. Thromb. Vasc. Biol. , vol.22 , pp. 887-893
    • Chavakis, E.1    Dimmeler, S.2
  • 47
    • 0037071892 scopus 로고    scopus 로고
    • Coordinated interaction of neurogenesis and angiogenesis in the adult songbird brain
    • Louissant, A. et al. (2002) Coordinated interaction of neurogenesis and angiogenesis in the adult songbird brain. Neuron 34, 945-960
    • (2002) Neuron , vol.34 , pp. 945-960
    • Louissant, A.1
  • 48
    • 0034718502 scopus 로고    scopus 로고
    • Regulation of vascular endothelial growth factor (VEGF) gene transcription by estrogen receptors α and β
    • Mueller, M.D. et al. (2000) Regulation of vascular endothelial growth factor (VEGF) gene transcription by estrogen receptors α and β. Proc. Natl. Acad. Sci. U. S. A. 97, 10972-10977
    • (2000) Proc. Natl. Acad. Sci. U. S. A. , vol.97 , pp. 10972-10977
    • Mueller, M.D.1
  • 49
    • 0034086611 scopus 로고    scopus 로고
    • Identification of functional estrogen receptor elements in the gene coding for the potent angiogenic factor vascular endothelial growth factor
    • Hyder, S.M. et al. (2000) Identification of functional estrogen receptor elements in the gene coding for the potent angiogenic factor vascular endothelial growth factor. Cancer Res. 60, 3183-3190
    • (2000) Cancer Res. , vol.60 , pp. 3183-3190
    • Hyder, S.M.1
  • 50
    • 0036713512 scopus 로고    scopus 로고
    • Microarray analysis of VEGF-responsive genes in myometrial endothelial cells
    • Weston, G.C. et al. (2002) Microarray analysis of VEGF-responsive genes in myometrial endothelial cells. Mol. Hum. Reprod. 8, 855-863
    • (2002) Mol. Hum. Reprod. , vol.8 , pp. 855-863
    • Weston, G.C.1
  • 51
    • 0032479933 scopus 로고    scopus 로고
    • Modulation of Bcl-2 expression: A potential component of estrogen protection in NT2 neurons
    • Singer, C.A. et al. (1998) Modulation of Bcl-2 expression: a potential component of estrogen protection in NT2 neurons. Neuroreport 9, 2565-2568
    • (1998) Neuroreport , vol.9 , pp. 2565-2568
    • Singer, C.A.1
  • 52
    • 0033178294 scopus 로고    scopus 로고
    • Estradiol modulates bcl-2 in cerebral ischemia: A potential role for estrogen receptors
    • Dubal, D.B. et al. (1999) Estradiol modulates bcl-2 in cerebral ischemia: a potential role for estrogen receptors. J. Neurosci. 19, 6385-6393
    • (1999) J. Neurosci. , vol.19 , pp. 6385-6393
    • Dubal, D.B.1
  • 53
    • 0035478068 scopus 로고    scopus 로고
    • Estrogen and Bcl-2: Gene induction and effect of transgene in experimental stroke
    • Alkayed, N.J. et al. (2001) Estrogen and Bcl-2: gene induction and effect of transgene in experimental stroke. J. Neurosci. 21, 7543-7550
    • (2001) J. Neurosci. , vol.21 , pp. 7543-7550
    • Alkayed, N.J.1
  • 54
    • 0037088929 scopus 로고    scopus 로고
    • Estrogen protects against global ischemia-induced neuronal death and prevents activation of apoptotic signaling cascades in the hippocampal CA1
    • Jover, T. et al. (2002) Estrogen protects against global ischemia-induced neuronal death and prevents activation of apoptotic signaling cascades in the hippocampal CA1. J. Neurosci. 22, 2115-2124
    • (2002) J. Neurosci. , vol.22 , pp. 2115-2124
    • Jover, T.1
  • 55
    • 0035831020 scopus 로고    scopus 로고
    • Nongenotropic, sex-nonspecific signaling through the estrogen or androgen receptors: Dissociation from transcriptional activity
    • Kousteni, S. et al. (2001) Nongenotropic, sex-nonspecific signaling through the estrogen or androgen receptors: dissociation from transcriptional activity. Cell 104, 719-730
    • (2001) Cell , vol.104 , pp. 719-730
    • Kousteni, S.1
  • 56
    • 0035823576 scopus 로고    scopus 로고
    • Ligand-dependent interaction of estrogen receptor-α with members of the forkhead transcription factor family
    • Schuur, E.R. et al. (2001) Ligand-dependent interaction of estrogen receptor-α with members of the forkhead transcription factor family. J. Biol. Chem. 276, 33554-33560
    • (2001) J. Biol. Chem. , vol.276 , pp. 33554-33560
    • Schuur, E.R.1
  • 57
    • 0037106145 scopus 로고    scopus 로고
    • Adult neurogenesis and neural stem cells of the central nervous system in mammals
    • Taupin, P. and Gage, F.H. (2002) Adult neurogenesis and neural stem cells of the central nervous system in mammals. J. Neurosci. Res. 69, 745-749
    • (2002) J. Neurosci. Res. , vol.69 , pp. 745-749
    • Taupin, P.1    Gage, F.H.2
  • 58
    • 0033660598 scopus 로고    scopus 로고
    • Effects of oestradiol on hippocampal circuitry
    • Woolley, C.S. (2000) Effects of oestradiol on hippocampal circuitry. Novartis Found. Symp. 230, 173-187
    • (2000) Novartis Found. Symp. , vol.230 , pp. 173-187
    • Woolley, C.S.1
  • 59
    • 0035882458 scopus 로고    scopus 로고
    • Sex differences and opposite effects of stress on dendritic spine density in the male versus female hippocampus
    • Shors, T.J. et al. (2001) Sex differences and opposite effects of stress on dendritic spine density in the male versus female hippocampus. J. Neurosci. 21, 6292-6297
    • (2001) J. Neurosci. , vol.21 , pp. 6292-6297
    • Shors, T.J.1
  • 60
    • 0033565292 scopus 로고    scopus 로고
    • Estrogen stimulates a transient increase in the number of new neurons in the dentate gyrus of the female rat
    • Tanapat, P. et al. (1999) Estrogen stimulates a transient increase in the number of new neurons in the dentate gyrus of the female rat. J. Neurosci. 19, 5792-5801
    • (1999) J. Neurosci. , vol.19 , pp. 5792-5801
    • Tanapat, P.1
  • 61
    • 0034667294 scopus 로고    scopus 로고
    • Regulation of hippocampal neurogenesis in adulthood
    • Gould, E. et al. (2000) Regulation of hippocampal neurogenesis in adulthood. Biol. Psychiatry 48, 715-720
    • (2000) Biol. Psychiatry , vol.48 , pp. 715-720
    • Gould, E.1
  • 62
    • 0034846836 scopus 로고    scopus 로고
    • Cortical neurogenesis in adult rats after transient middle cerebral artery occlusion
    • Jiang, W. et al. (2001) Cortical neurogenesis in adult rats after transient middle cerebral artery occlusion. Stroke 32, 1201-1207
    • (2001) Stroke , vol.32 , pp. 1201-1207
    • Jiang, W.1
  • 63
    • 0032189609 scopus 로고    scopus 로고
    • Increased neurogenesis in the dentate gyrus after transient global ischemia in gerbils
    • Liu, J. et al. (1998) Increased neurogenesis in the dentate gyrus after transient global ischemia in gerbils. J. Neurosci. 18, 7768-7778
    • (1998) J. Neurosci. , vol.18 , pp. 7768-7778
    • Liu, J.1
  • 64
    • 0035836656 scopus 로고    scopus 로고
    • Neurogenesis in dentate subgranular zone and rostral subventricular zone after focal cerebral ischemia in the rat
    • Jin, K. et al. (2001) Neurogenesis in dentate subgranular zone and rostral subventricular zone after focal cerebral ischemia in the rat. Proc. Natl. Acad. Sci. U. S. A. 98, 4710-4715
    • (2001) Proc. Natl. Acad. Sci. U. S. A. , vol.98 , pp. 4710-4715
    • Jin, K.1
  • 65
    • 0035239031 scopus 로고    scopus 로고
    • Neuroprotection by estradiol
    • Garcia-Segura, L.M. et al. (2001) Neuroprotection by estradiol. Prog. Neurobiol. 63, 29-60
    • (2001) Prog. Neurobiol. , vol.63 , pp. 29-60
    • Garcia-Segura, L.M.1
  • 66
    • 0033567829 scopus 로고    scopus 로고
    • Role of astroglia in estrogen regulation of synaptic plasticity and brain repair
    • Garcia-Segura, L.M. et al. (1999) Role of astroglia in estrogen regulation of synaptic plasticity and brain repair. J. Neurobiol. 40, 574-584
    • (1999) J. Neurobiol. , vol.40 , pp. 574-584
    • Garcia-Segura, L.M.1
  • 67
    • 0035876966 scopus 로고    scopus 로고
    • Brain aromatase is neuroprotective
    • Azcoitia, I. et al. (2001) Brain aromatase is neuroprotective. J. Neurobiol. 47, 318-329
    • (2001) J. Neurobiol. , vol.47 , pp. 318-329
    • Azcoitia, I.1
  • 68
    • 0025821731 scopus 로고
    • The compensatory 'rebound' of reactive astrogliosis: Glial fibrillary acidic protein immunohistochemical analysis of reactive astrogliosis after a puncture wound to the brain of rats with portocaval anastomosis
    • Ma, K.C. et al. (1991) The compensatory 'rebound' of reactive astrogliosis: glial fibrillary acidic protein immunohistochemical analysis of reactive astrogliosis after a puncture wound to the brain of rats with portocaval anastomosis. Acta Neuropathol. (Berl.) 82, 72-77
    • (1991) Acta Neuropathol. (Berl.) , vol.82 , pp. 72-77
    • Ma, K.C.1
  • 69
    • 0033752744 scopus 로고    scopus 로고
    • Antiinflammatory effects of estrogen on microglial activation
    • Bruce-Keller, A.J. et al. (2000) Antiinflammatory effects of estrogen on microglial activation. Endocrinology 141, 3646-3656
    • (2000) Endocrinology , vol.141 , pp. 3646-3656
    • Bruce-Keller, A.J.1
  • 70
    • 0035852657 scopus 로고    scopus 로고
    • Estrogen receptor α, not β, is a critical link in estradiol-mediated protection against brain injury
    • Dubal, D.B. (2001) Estrogen receptor α, not β, is a critical link in estradiol-mediated protection against brain injury. Proc. Natl. Acad. Sci. U. S. A. 98, 1952-1957
    • (2001) Proc. Natl. Acad. Sci. U. S. A. , vol.98 , pp. 1952-1957
    • Dubal, D.B.1
  • 71
    • 0035448951 scopus 로고    scopus 로고
    • Adenoviral brain-derived neurotrophic factor induces both neostriatal and olfactory neuronal recruitment from endogenous progenitor cells in the adult forebrain
    • Benraiss, A. et al. (2001) Adenoviral brain-derived neurotrophic factor induces both neostriatal and olfactory neuronal recruitment from endogenous progenitor cells in the adult forebrain. J. Neurosci. 21, 6718-6731
    • (2001) J. Neurosci. , vol.21 , pp. 6718-6731
    • Benraiss, A.1
  • 72
    • 0035871646 scopus 로고    scopus 로고
    • Differential mechanisms of neuroprotection by 17 β-estradiol in apoptotic versus necrotic neurodegeneration
    • Harms, C. et al. (2001) Differential mechanisms of neuroprotection by 17 β-estradiol in apoptotic versus necrotic neurodegeneration. J. Neurosci. 21, 2600-2609
    • (2001) J. Neurosci. , vol.21 , pp. 2600-2609
    • Harms, C.1
  • 73
    • 0030753755 scopus 로고    scopus 로고
    • Rapid membrane effects of steroids in neuroblastoma cells: Effects of estrogen on mitogen activated protein kinase signaling cascade and c-fos immediate early gene transcription
    • Watters, J.J. et al. (1997) Rapid membrane effects of steroids in neuroblastoma cells: effects of estrogen on mitogen activated protein kinase signaling cascade and c-fos immediate early gene transcription. Endocrinology 138, 4030-4033
    • (1997) Endocrinology , vol.138 , pp. 4030-4033
    • Watters, J.J.1
  • 74
    • 0033648336 scopus 로고    scopus 로고
    • Neuroprotective effects of phenolic A ring oestrogens
    • Green, P.S. et al. (2000) Neuroprotective effects of phenolic A ring oestrogens. Novartis Found. Symp. 230, 202-213
    • (2000) Novartis Found. Symp. , vol.230 , pp. 202-213
    • Green, P.S.1
  • 75
    • 0036790627 scopus 로고    scopus 로고
    • Neuroprotective effects of a novel non-receptor-binding estrogen analogue: In vitro and in vivo analysis
    • Liu, R. et al. (2002) Neuroprotective effects of a novel non-receptor-binding estrogen analogue: in vitro and in vivo analysis. Stroke 33, 2485-2491
    • (2002) Stroke , vol.33 , pp. 2485-2491
    • Liu, R.1
  • 76
    • 0036239624 scopus 로고    scopus 로고
    • The estrogen receptor is not essential for all estrogen neuroprotection: New evidence from a new analog
    • Xia, S. et al. (2002) The estrogen receptor is not essential for all estrogen neuroprotection: new evidence from a new analog. Neurobiol. Dis. 9, 282-293
    • (2002) Neurobiol. Dis. , vol.9 , pp. 282-293
    • Xia, S.1
  • 77
    • 0030903206 scopus 로고    scopus 로고
    • Neuroprotection against oxidative stress by estrogens: Structure-activity relationship
    • Behl, C. et al. (1997) Neuroprotection against oxidative stress by estrogens: structure-activity relationship. Mol. Pharmacol. 51, 535-541
    • (1997) Mol. Pharmacol. , vol.51 , pp. 535-541
    • Behl, C.1
  • 78
    • 0035051461 scopus 로고    scopus 로고
    • Relaxant effects of 17-β-estradiol in cerebral arteries through Ca(2+) entry inhibition
    • Salom, J.B. et al. (2001) Relaxant effects of 17-β-estradiol in cerebral arteries through Ca(2+) entry inhibition. J. Cereb. Blood Flow Metab. 21, 422-429
    • (2001) J. Cereb. Blood Flow Metab. , vol.21 , pp. 422-429
    • Salom, J.B.1
  • 79
    • 0033578667 scopus 로고    scopus 로고
    • Acute activation of Maxi-K channels (hSlo) by estradiol binding to the β subunit
    • Valverde, M.A. etal. (1999) Acute activation of Maxi-K channels (hSlo) by estradiol binding to the β subunit. Science 285, 1929-1931
    • (1999) Science , vol.285 , pp. 1929-1931
    • Valverde, M.A.1
  • 80
    • 0031904678 scopus 로고    scopus 로고
    • Estrogen-mediated neuroprotection after experimental stroke in male rats
    • Toung, T. et al. (1998) Estrogen-mediated neuroprotection after experimental stroke in male rats. Stroke 29, 1666-1670
    • (1998) Stroke , vol.29 , pp. 1666-1670
    • Toung, T.1
  • 81
    • 0030700217 scopus 로고    scopus 로고
    • Estrogens may reduce mortality and ischemic damage caused by middle cerebral artery occlusion in the female rat
    • Simpkins, J.W. et al. (1997) Estrogens may reduce mortality and ischemic damage caused by middle cerebral artery occlusion in the female rat. J. Neurosurg. 87, 724-730
    • (1997) J. Neurosurg. , vol.87 , pp. 724-730
    • Simpkins, J.W.1
  • 82
    • 0037081302 scopus 로고    scopus 로고
    • Proestrus levels ofestradiol during transient global cerebral ischemia improves the histological outcome of the hippocampal CA1 region: Perfusion dependent and independent mechanisms
    • He, Z. et al. (2002) Proestrus levels ofestradiol during transient global cerebral ischemia improves the histological outcome of the hippocampal CA1 region: perfusion dependent and independent mechanisms. J. Neurol. Sci. 193, 79-87
    • (2002) J. Neurol. Sci. , vol.193 , pp. 79-87
    • He, Z.1
  • 83
    • 0035910642 scopus 로고    scopus 로고
    • Association of serum estrogen level and ischemic neuroprotection in female rats
    • Liao, S. et al. (2001) Association of serum estrogen level and ischemic neuroprotection in female rats. Neurosci. Lett. 297, 159-162
    • (2001) Neurosci. Lett. , vol.297 , pp. 159-162
    • Liao, S.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.