A Wrench-Shaped Synthetic Molecule that Modulates a Transcription Factor-Coactivator Interaction

Journal of the American Chemical Society

Volumn 126, Issue 11, 2004, Pages 3461-3471

  Shimogawa, Hiroki ^a,b   Kwon, Youngjoo ^a   Mao, Qian ^a   Kawazoe, Yoshinori ^a   Choi, Yongmun ^a   Asada, Shinichi ^a   Kigoshi, Hideo ^b   Uesugi, Motonari ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF TSUKUBA   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; NUCLEAR MAGNETIC RESONANCE; PROTEINS; SYNTHESIS (CHEMICAL);

SYNTHETIC MOLECULES; TRANSCRIPTION;

GENES;

DESIGNER DRUG; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR ESX; TRANSCRIPTION FACTOR SUR2; UNCLASSIFIED DRUG; WRENCHNOLOL;

AQUEOUS SOLUTION; ARTICLE; BIOTINYLATION; CHEMICAL MODIFICATION; DRUG DESIGN; FLUORESCENCE; GENE DISRUPTION; GENETIC TRANSCRIPTION; MOLECULAR MODEL; NUCLEAR MAGNETIC RESONANCE; ONCOGENE NEU; PERMEABILITY; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; PROTEIN TARGETING; SOLUBILITY; STRUCTURE ACTIVITY RELATION; SYNTHESIS; TRANSCRIPTION REGULATION;

ADAMANTANE; BIOMIMETIC MATERIALS; BRIDGED COMPOUNDS; CELL LINE, TUMOR; DNA-BINDING PROTEINS; FLUORESCEIN; GENES, ERBB-2; HUMANS; INDOLES; MODELS, MOLECULAR; PROPANOLS; PROTO-ONCOGENE PROTEINS; RECEPTOR, ERBB-2; STRUCTURE-ACTIVITY RELATIONSHIP; TRANS-ACTIVATION (GENETICS); TRANS-ACTIVATORS; TRANSCRIPTION FACTORS;

EID: 1642291800     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja038855+     Document Type: Article

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