-
1
-
-
0022328481
-
A eukaryotic transcriptional activator bearing the DNA binding specificity of a prokaryotic repressor
-
Brent, R. & Ptashne, M. (1985). A eukaryotic transcriptional activator bearing the DNA binding specificity of a prokaryotic repressor. Cell 43, 729-736.
-
(1985)
Cell
, vol.43
, pp. 729-736
-
-
Brent, R.1
Ptashne, M.2
-
2
-
-
0029278672
-
The dangers of 'splicing and dicing': On the use of chimeric transcriptional activators in vitro
-
Kodadek, T. & Johnston, S.A. (1995). The dangers of 'splicing and dicing': on the use of chimeric transcriptional activators in vitro. Chem. Biol. 2, 187-194.
-
(1995)
Chem. Biol.
, vol.2
, pp. 187-194
-
-
Kodadek, T.1
Johnston, S.A.2
-
3
-
-
0029058555
-
Transcriptional regulation in the yeast GAL gene family: A complex genetic network
-
Lohr, D., Venkov, P. & Zlatanova, J. (1995). Transcriptional regulation in the yeast GAL gene family: a complex genetic network. FASEB J. 9, 777-787.
-
(1995)
FASEB J.
, vol.9
, pp. 777-787
-
-
Lohr, D.1
Venkov, P.2
Zlatanova, J.3
-
4
-
-
0023643044
-
Interaction of positive and negative regulatory proteins in the galactose regulation of yeast
-
Johnston, S.A., Salmeron, J.M. Jr. & Dincher, S.S. (1987). Interaction of positive and negative regulatory proteins in the galactose regulation of yeast. Cell 50, 143-146.
-
(1987)
Cell
, vol.50
, pp. 143-146
-
-
Johnston, S.A.1
Salmeron Jr., J.M.2
Dincher, S.S.3
-
5
-
-
0026728801
-
Nondissociation of GAL4 and GAL80 in vivo after galactose induction
-
Leuther, K.K. & Johnston, S.A. (1992). Nondissociation of GAL4 and GAL80 in vivo after galactose induction. Science 256, 1333-1335.
-
(1992)
Science
, vol.256
, pp. 1333-1335
-
-
Leuther, K.K.1
Johnston, S.A.2
-
6
-
-
0031126702
-
Rel/NF-kappa B and I kappa B proteins, an overview
-
May, M.J. & Ghosh, S. (1997). Rel/NF-kappa B and I kappa B proteins, an overview. Semin. Cancer Biol. 8, 63-73.
-
(1997)
Semin. Cancer Biol.
, vol.8
, pp. 63-73
-
-
May, M.J.1
Ghosh, S.2
-
7
-
-
0029797189
-
The mechanism of action of cyclosporin A and FK-506
-
Ho, S., et al. & Crabtree, G.R. (1996). The mechanism of action of cyclosporin A and FK-506. Clin, Immunol. Immunopathol. 80, S40-S45.
-
(1996)
Clin, Immunol. Immunopathol.
, vol.80
-
-
Ho, S.1
Crabtree, G.R.2
-
8
-
-
0026575932
-
The mechanism of action of cyclosporin A and FK506
-
Schreiber, S.L & Crabtree, G.R. (1992). The mechanism of action of cyclosporin A and FK506. Immunol. Today 13, 136-42.
-
(1992)
Immunol. Today
, vol.13
, pp. 136-142
-
-
Schreiber, S.L.1
Crabtree, G.R.2
-
9
-
-
0025826967
-
Atomic structure of FKBP-FK506, an immunophilin-immunosuppressant complex
-
Van, D.G., Standaert, R.F., Karplus, P.A., Schreiber, S.L. & Clardy, J. (1991). Atomic structure of FKBP-FK506, an immunophilin-immunosuppressant complex. Science 252, 839-42.
-
(1991)
Science
, vol.252
, pp. 839-842
-
-
Van, D.G.1
Standaert, R.F.2
Karplus, P.A.3
Schreiber, S.L.4
Clardy, J.5
-
10
-
-
0028772888
-
Crystal structures of cyclophilin A complexed with cyclosporin A and N-methyl-4-[(E)-2-butenyl]-4,4-dimethylthreonine cyclosporin A
-
Ke, H., et al. & Walsh, CT. (1994). Crystal structures of cyclophilin A complexed with cyclosporin A and N-methyl-4-[(E)-2-butenyl]-4,4-dimethylthreonine cyclosporin A. Structure 2, 33-44.
-
(1994)
Structure
, vol.2
, pp. 33-44
-
-
Ke, H.1
Walsh, C.T.2
-
11
-
-
0025893168
-
Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes
-
Liu, J., et al. & Schreiber, S.L. (1991). Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes. Cell 66, 807-815.
-
(1991)
Cell
, vol.66
, pp. 807-815
-
-
Liu, J.1
Schreiber, S.L.2
-
12
-
-
0028885878
-
Immunosuppressive drugs prevent a rapid dephosphorylation of transcription factor NFAT1 in stimulated immune cells
-
Shaw, K.T.Y., et al. & Hogan, P.G. (1995). Immunosuppressive drugs prevent a rapid dephosphorylation of transcription factor NFAT1 in stimulated immune cells. Proc. Natl Acad. Sci. USA 92, 11205-11209.
-
(1995)
Proc. Natl Acad. Sci. USA
, vol.92
, pp. 11205-11209
-
-
Shaw, K.T.Y.1
Hogan, P.G.2
-
13
-
-
15844416253
-
Calcineurin binds the transcription factor NFAT1 and reversibly regulates its activity
-
Loh, C., et al. & Rao, A. (1996). Calcineurin binds the transcription factor NFAT1 and reversibly regulates its activity. J. Biol. Chem. 271, 10884-10891.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 10884-10891
-
-
Loh, C.1
Rao, A.2
-
14
-
-
0030296634
-
Three-part inventions: Intracellular signalling and induced proximity
-
Crabtree, G.R. & Schreiber, S.L. (1996). Three-part inventions: intracellular signalling and induced proximity. Trends Biochem. Sci. 21, 418-422.
-
(1996)
Trends Biochem. Sci.
, vol.21
, pp. 418-422
-
-
Crabtree, G.R.1
Schreiber, S.L.2
-
15
-
-
0027756895
-
Controlling signal transduction with synthetic ligands
-
Spencer, D.M., Wandless, T.J., Schreiber, S.L. & Crabtree, G.R. (1993). Controlling signal transduction with synthetic ligands. Science 262, 1019-1024.
-
(1993)
Science
, vol.262
, pp. 1019-1024
-
-
Spencer, D.M.1
Wandless, T.J.2
Schreiber, S.L.3
Crabtree, G.R.4
-
16
-
-
0029737867
-
Dimeric ligands define a role for transcriptional activation domains in reinitiation
-
Ho, S.N., Biggar, S.R., Spencer, D.M., Schreiber, S.L. & Crabtree, G.R. (1996). Dimeric ligands define a role for transcriptional activation domains in reinitiation. Nature 382, 822-826.
-
(1996)
Nature
, vol.382
, pp. 822-826
-
-
Ho, S.N.1
Biggar, S.R.2
Spencer, D.M.3
Schreiber, S.L.4
Crabtree, G.R.5
-
17
-
-
0029846871
-
The general transcription factors of RNA polymerase II
-
Orphanides, G., Lagrange, T. & Reinberg, D. (1996). The general transcription factors of RNA polymerase II. Genes Dev. 10, 2657-2683.
-
(1996)
Genes Dev.
, vol.10
, pp. 2657-2683
-
-
Orphanides, G.1
Lagrange, T.2
Reinberg, D.3
-
18
-
-
0027197725
-
General initiation factors for RNA polymerase II
-
Conaway, R.C. & Conaway, J.W. (1993). General initiation factors for RNA polymerase II. Annu. Rev. Biochem. 62, 161-190.
-
(1993)
Annu. Rev. Biochem.
, vol.62
, pp. 161-190
-
-
Conaway, R.C.1
Conaway, J.W.2
-
19
-
-
0030013203
-
Biochemistry and structural biology of transcription factor IID (TFIID)
-
Burley, S.K. & Roeder, R.G. (1996). Biochemistry and structural biology of transcription factor IID (TFIID). Ann. Rev. Biochem. 65, 769-799.
-
(1996)
Ann. Rev. Biochem.
, vol.65
, pp. 769-799
-
-
Burley, S.K.1
Roeder, R.G.2
-
20
-
-
0027483012
-
Co-crystal structure of TBP recognizing the minor groove of a TATA element
-
Kim, J.L., Nikolov, B.D. & Burley, S.K. (1993). Co-crystal structure of TBP recognizing the minor groove of a TATA element. Nature 365, 520-527.
-
(1993)
Nature
, vol.365
, pp. 520-527
-
-
Kim, J.L.1
Nikolov, B.D.2
Burley, S.K.3
-
21
-
-
0027504913
-
Crystal structure of a yeast TBP/TATA complex
-
Kim, Y., Geiger, J.H., Hahn, S. & Sigler, P.B. (1993). Crystal structure of a yeast TBP/TATA complex. Nature 365, 512-520.
-
(1993)
Nature
, vol.365
, pp. 512-520
-
-
Kim, Y.1
Geiger, J.H.2
Hahn, S.3
Sigler, P.B.4
-
22
-
-
0026091129
-
Isolation of coactivators associated with the TATA binding protein that mediate transcriptional activation
-
Dynlacht, B.D., Hoey, T. & Tjian, R. (1991). Isolation of coactivators associated with the TATA binding protein that mediate transcriptional activation. Cell 66, 563-576.
-
(1991)
Cell
, vol.66
, pp. 563-576
-
-
Dynlacht, B.D.1
Hoey, T.2
Tjian, R.3
-
23
-
-
0026665954
-
Kinetic analysis of yeast TFIID-TATA box complex formation suggests a multi-step pathway
-
Hoopes, B.C., LeBlanc, J.F. & Hawley, D. (1992). Kinetic analysis of yeast TFIID-TATA box complex formation suggests a multi-step pathway. J. Biol. Chem. 267, 11539-11547.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 11539-11547
-
-
Hoopes, B.C.1
LeBlanc, J.F.2
Hawley, D.3
-
24
-
-
0029014933
-
A kinetic mechanism by which the TATA-binding protein achieves sequence specific DNA binding
-
Coleman, R.A., & Pugh, B.F. (1995). A kinetic mechanism by which the TATA-binding protein achieves sequence specific DNA binding. J. Biol. Chem. 270, 13850-13859.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 13850-13859
-
-
Coleman, R.A.1
Pugh, B.F.2
-
25
-
-
0028345413
-
Direct recognition of initiator elements by a component of the transcription factor IID complex
-
Kaufmann, J. & Smale, S. (1994). Direct recognition of initiator elements by a component of the transcription factor IID complex. Genes Dev. 8, 821-829.
-
(1994)
Genes Dev.
, vol.8
, pp. 821-829
-
-
Kaufmann, J.1
Smale, S.2
-
26
-
-
0028179052
-
Drosophila TAFII150: Similarity to yeast gene TSM-1 and specific binding to core promoter DNA
-
Verrijzer, C.P., Yokomori, K., Chen, J.-L. & Tjian, R. (1994). Drosophila TAFII150: similarity to yeast gene TSM-1 and specific binding to core promoter DNA. Science 264, 933-941.
-
(1994)
Science
, vol.264
, pp. 933-941
-
-
Verrijzer, C.P.1
Yokomori, K.2
Chen, J.-L.3
Tjian, R.4
-
27
-
-
0029055811
-
Binding of TAFs to core elements directs promoter selectivity by RNA polymerase II
-
Verrijzer, C.P., Chen, J.-L. Yokomori, K. & Tjian, R. (1995). Binding of TAFs to core elements directs promoter selectivity by RNA polymerase II. Cell 81, 1115-1125.
-
(1995)
Cell
, vol.81
, pp. 1115-1125
-
-
Verrijzer, C.P.1
Chen, J.-L.2
Yokomori, K.3
Tjian, R.4
-
29
-
-
0028305843
-
Phosphorylation of RNA polymerase II C-terminal domain and transcriptional elongation
-
O'Brien, T., Hardin, S., Greenleaf, A. & Lis, J.T. (1994). Phosphorylation of RNA polymerase II C-terminal domain and transcriptional elongation. Nature 370, 75-77.
-
(1994)
Nature
, vol.370
, pp. 75-77
-
-
O'Brien, T.1
Hardin, S.2
Greenleaf, A.3
Lis, J.T.4
-
30
-
-
0024977414
-
Five intermediate complexes in transcription initiation by RNA polymerase II
-
Burtowski, S., Hahn, S., Guarente, L. & Sharp, P.A. (1989). Five intermediate complexes in transcription initiation by RNA polymerase II. Cell 56, 549-561.
-
(1989)
Cell
, vol.56
, pp. 549-561
-
-
Burtowski, S.1
Hahn, S.2
Guarente, L.3
Sharp, P.A.4
-
31
-
-
0029930779
-
Crystal structure of the yeast TFIIA/TBP/DNA complex
-
Geiger, J.H., Hahn, S., Lee, S. & Sigler, P.B. (1996). Crystal structure of the yeast TFIIA/TBP/DNA complex. Science 272, 830-836.
-
(1996)
Science
, vol.272
, pp. 830-836
-
-
Geiger, J.H.1
Hahn, S.2
Lee, S.3
Sigler, P.B.4
-
32
-
-
0031883573
-
The yeast TAF145 inhibitory domain and TFIIA competitively bind to TATA-binding protein
-
Kokubo, T., Swanson, M.J., Nishikawa, J.-I., Hinnebusch, A.G. & Nakatani, Y. (1998). The yeast TAF145 inhibitory domain and TFIIA competitively bind to TATA-binding protein. Mol. Cell. Biol. 18, 1003-1012.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 1003-1012
-
-
Kokubo, T.1
Swanson, M.J.2
Nishikawa, J.-I.3
Hinnebusch, A.G.4
Nakatani, Y.5
-
33
-
-
0027253864
-
A multisubunit complex associated with the RNA polymerase II CTD and TATA-binding protein in yeast
-
Thompson, C.M. Koleske, A.J. Chao, D.M. & Young, R.A. (1993). A multisubunit complex associated with the RNA polymerase II CTD and TATA-binding protein in yeast Cell 73, 1361-1375.
-
(1993)
Cell
, vol.73
, pp. 1361-1375
-
-
Thompson, C.M.1
Koleske, A.J.2
Chao, D.M.3
Young, R.A.4
-
34
-
-
0028347674
-
An RNA polymerase II holoenzyme responsive to activators
-
Koleske, A.J. & Young, R.A. (1994). An RNA polymerase II holoenzyme responsive to activators. Nature 368, 466-469.
-
(1994)
Nature
, vol.368
, pp. 466-469
-
-
Koleske, A.J.1
Young, R.A.2
-
35
-
-
0028978670
-
Crystal structure of a TFIIB-TBP-TATA element ternary complex
-
Nikolov, D.B., et al. & Burley, S.K. (1995). Crystal structure of a TFIIB-TBP-TATA element ternary complex. Nature 377, 119-128.
-
(1995)
Nature
, vol.377
, pp. 119-128
-
-
Nikolov, D.B.1
Burley, S.K.2
-
36
-
-
0029993645
-
Picking up the TAB
-
Burley, S.K. (1996). Picking up the TAB. Nature 381, 112-113.
-
(1996)
Nature
, vol.381
, pp. 112-113
-
-
Burley, S.K.1
-
37
-
-
0030217852
-
Mechanisms of transcriptional activation in vivo: Two steps forward
-
Stargell, L.A. & Struhl, K. (1996). Mechanisms of transcriptional activation in vivo: two steps forward. Trends Genet. 12, 311-315.
-
(1996)
Trends Genet.
, vol.12
, pp. 311-315
-
-
Stargell, L.A.1
Struhl, K.2
-
38
-
-
0030248746
-
Mediator of transcriptional regulation
-
Bjorkland, S. & Kim, Y.-J. (1996). Mediator of transcriptional regulation. Trends Biochem. Sci. 21, 335-337.
-
(1996)
Trends Biochem. Sci.
, vol.21
, pp. 335-337
-
-
Bjorkland, S.1
Kim, Y.-J.2
-
39
-
-
0028282551
-
A multiprotein mediator of transcriptional activation and its interaction with the C-terminal repeat domain of RNA polymerase II
-
Kim, Y.-L., Bjorklund, S., Li, Y., Sayre, M.H. & Kornberg, R.D. (1994). A multiprotein mediator of transcriptional activation and its interaction with the C-terminal repeat domain of RNA polymerase II. Cell 77, 599-608.
-
(1994)
Cell
, vol.77
, pp. 599-608
-
-
Kim, Y.-L.1
Bjorklund, S.2
Li, Y.3
Sayre, M.H.4
Kornberg, R.D.5
-
40
-
-
0030947346
-
Evidence for a mediator cycle at the initiation of transcription
-
Svejstrup, J.Q., et al. & Kornberg, R.D. (1997). Evidence for a mediator cycle at the initiation of transcription. Proc. Natl Acad. Sci. USA 94, 6075-6078.
-
(1997)
Proc. Natl Acad. Sci. USA
, vol.94
, pp. 6075-6078
-
-
Svejstrup, J.Q.1
Kornberg, R.D.2
-
41
-
-
0029074137
-
Recycling of the general transcription factors during RNA polymerase II transcription
-
Zawel, L., Kumar, K.P. & Reinberg, D. (1995). Recycling of the general transcription factors during RNA polymerase II transcription. Genes Dev. 9, 1479-1490.
-
(1995)
Genes Dev.
, vol.9
, pp. 1479-1490
-
-
Zawel, L.1
Kumar, K.P.2
Reinberg, D.3
-
42
-
-
0026263755
-
The Zta trans-activator protein stabilizes TFIID association with promoter DNA by direct protein-protein interaction
-
Lieberman, P.M. & Berk, A.J. (1991). The Zta trans-activator protein stabilizes TFIID association with promoter DNA by direct protein-protein interaction. Genes Dev. 5, 2441-2454.
-
(1991)
Genes Dev.
, vol.5
, pp. 2441-2454
-
-
Lieberman, P.M.1
Berk, A.J.2
-
43
-
-
0029129287
-
Mutations on the DNA-binding surface of TATA-binding protein can specifically impair the response to acidic activators in vivo
-
Lee, M. & Struhl, K. (1995). Mutations on the DNA-binding surface of TATA-binding protein can specifically impair the response to acidic activators in vivo. Mol. Cell. Biol. 15, 5461-5469.
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 5461-5469
-
-
Lee, M.1
Struhl, K.2
-
44
-
-
0028073410
-
Increased recruitment of TATA-binding protein to the promoter by transcriptional activation domains in vivo
-
Klein, C. & Struhl, K. (1994). Increased recruitment of TATA-binding protein to the promoter by transcriptional activation domains in vivo. Science 266, 280-282.
-
(1994)
Science
, vol.266
, pp. 280-282
-
-
Klein, C.1
Struhl, K.2
-
45
-
-
0029005178
-
Contact with a component of the polymerase II holoenzyme suffices for gene activation
-
Barberis, A., et al. & Ptashne, M. (1995). Contact with a component of the polymerase II holoenzyme suffices for gene activation. Cell 81, 359-368.
-
(1995)
Cell
, vol.81
, pp. 359-368
-
-
Barberis, A.1
Ptashne, M.2
-
46
-
-
0029780704
-
Gene activation by recruitment of the RNA polymerase II holoenzyme
-
Farrell, S., Simkovich, N., Yu, Y., Barberis, A. & Ptashne, M. (1996). Gene activation by recruitment of the RNA polymerase II holoenzyme. Genes Dev. 10, 2358-2367.
-
(1996)
Genes Dev.
, vol.10
, pp. 2358-2367
-
-
Farrell, S.1
Simkovich, N.2
Yu, Y.3
Barberis, A.4
Ptashne, M.5
-
47
-
-
0028108925
-
Assembly of recombinant TFIID reveals differential coactivator requirements for distinct transcriptional activators
-
Chen, J.-L., Attardi, L.D., Verrijzer, C.P., Yokomori, K. & Tjian, R. (1994). Assembly of recombinant TFIID reveals differential coactivator requirements for distinct transcriptional activators. Cell 79, 93-105.
-
(1994)
Cell
, vol.79
, pp. 93-105
-
-
Chen, J.-L.1
Attardi, L.D.2
Verrijzer, C.P.3
Yokomori, K.4
Tjian, R.5
-
48
-
-
0029417005
-
IIs directing synergistic activation of transcription
-
IIs directing synergistic activation of transcription. Science 270, 1783-1788.
-
(1995)
Science
, vol.270
, pp. 1783-1788
-
-
Sauer, F.1
Hansen, S.K.2
Tjian, R.3
-
49
-
-
0030249382
-
TAFs mediate transcriptional activation and promoter selectivity
-
Verrijzer, C.P. & Tjian, R. (1996). TAFs mediate transcriptional activation and promoter selectivity. Trends Biochem. Sci. 9, 338-342.
-
(1996)
Trends Biochem. Sci.
, vol.9
, pp. 338-342
-
-
Verrijzer, C.P.1
Tjian, R.2
-
50
-
-
0029811986
-
TBP-associated factors are not generally required for transcriptional activation in yeast
-
Moqtaderi, Z., Bai, Y., Poon, D., Weil, P.A. & Struhl, K. (1996). TBP-associated factors are not generally required for transcriptional activation in yeast. Nature 383, 188-191.
-
(1996)
Nature
, vol.383
, pp. 188-191
-
-
Moqtaderi, Z.1
Bai, Y.2
Poon, D.3
Weil, P.A.4
Struhl, K.5
-
51
-
-
0029780094
-
II90 is required for cell-cycle progression through G2/M but not for general transcription activation
-
II90 is required for cell-cycle progression through G2/M but not for general transcription activation. Genes Dev. 10, 2368-2380.
-
(1996)
Genes Dev.
, vol.10
, pp. 2368-2380
-
-
Apone, L.M.1
Virbasius, C.A.2
Reese, J.C.3
Green, M.R.4
-
54
-
-
0030856701
-
The HIV transactivator Tat binds to the CDK-activating kinase and activates the phosphorylation of the carboxy-terminal domain of RNA polymerase II
-
Cujec, T.P., et al. & Peterlin, B.M. (1997). The HIV transactivator Tat binds to the CDK-activating kinase and activates the phosphorylation of the carboxy-terminal domain of RNA polymerase II. Genes Dev. 11, 2645-2657.
-
(1997)
Genes Dev.
, vol.11
, pp. 2645-2657
-
-
Cujec, T.P.1
Peterlin, B.M.2
-
56
-
-
0022817308
-
RNA polymerase II interacts with the promoter region of the noninduced hsp70 gene in Drosophila melanogaster
-
Gilmour, D.S. & Lis, J.T. (1986). RNA polymerase II interacts with the promoter region of the noninduced hsp70 gene in Drosophila melanogaster. Mol. Cell. Biol. 6, 3984-3989.
-
(1986)
Mol. Cell. Biol.
, vol.6
, pp. 3984-3989
-
-
Gilmour, D.S.1
Lis, J.T.2
-
57
-
-
14444281157
-
P-TEF kinase is required for HIV Tat transcriptional activation in vivo and in vitro
-
Mancebo, H.S.Y., et al. & Flores, O. (1997). P-TEF kinase is required for HIV Tat transcriptional activation in vivo and in vitro. Genes Dev. 11, 2633-2644.
-
(1997)
Genes Dev.
, vol.11
, pp. 2633-2644
-
-
Mancebo, H.S.Y.1
Flores, O.2
-
58
-
-
0026599021
-
Chromatin as an essential part of the transcriptional mechanism
-
Felsenfeld, G. (1992). Chromatin as an essential part of the transcriptional mechanism. Nature 355, 219-224.
-
(1992)
Nature
, vol.355
, pp. 219-224
-
-
Felsenfeld, G.1
-
59
-
-
0029917840
-
Repression and activation by multiprotein complexes that alter chromatin structure
-
Kingston, R.E., Bunker, C.A. & Imbalzano, A.N. (1996). Repression and activation by multiprotein complexes that alter chromatin structure. Genes Dev. 10, 905-920.
-
(1996)
Genes Dev.
, vol.10
, pp. 905-920
-
-
Kingston, R.E.1
Bunker, C.A.2
Imbalzano, A.N.3
-
60
-
-
0032488855
-
Eukaryotic transcription: An interlaced network of transcription factors and chromatin-modifying machines
-
Kadonaga, J.T. (1998). Eukaryotic transcription: An interlaced network of transcription factors and chromatin-modifying machines. Cell 92, 307-313.
-
(1998)
Cell
, vol.92
, pp. 307-313
-
-
Kadonaga, J.T.1
-
61
-
-
0029925512
-
Special HATs for special occasions: Linking histone acetylation to chromatin assembly and gene activation
-
Brownell, J.E. & Allis, C.D. (1996). Special HATs for special occasions: linking histone acetylation to chromatin assembly and gene activation. Curr. Opin. Genet Dev. 6, 176-184.
-
(1996)
Curr. Opin. Genet Dev.
, vol.6
, pp. 176-184
-
-
Brownell, J.E.1
Allis, C.D.2
-
62
-
-
0032484989
-
Retinoblastoma protein recruits histone deacetylase to repress transcription
-
Brehm, A., et al. & Kouzardis, T. (1998). Retinoblastoma protein recruits histone deacetylase to repress transcription. Nature 391, 597-601.
-
(1998)
Nature
, vol.391
, pp. 597-601
-
-
Brehm, A.1
Kouzardis, T.2
-
63
-
-
0032484904
-
Retinoblastoma protein represses transcription by recruiting a histone deacetylase
-
Magnaghi-Jaulin, L., et al. & Harel-Bellan, A. (1998). Retinoblastoma protein represses transcription by recruiting a histone deacetylase. Nature 391, 601-605.
-
(1998)
Nature
, vol.391
, pp. 601-605
-
-
Magnaghi-Jaulin, L.1
Harel-Bellan, A.2
-
64
-
-
0029932598
-
A mammalian histone deacetylase related to the yeast transcriptional regulator Rpd3p
-
Taunton, J., Hassig, C.A. & Schreiber, S.L. (1996). A mammalian histone deacetylase related to the yeast transcriptional regulator Rpd3p. Science 272, 408-411.
-
(1996)
Science
, vol.272
, pp. 408-411
-
-
Taunton, J.1
Hassig, C.A.2
Schreiber, S.L.3
-
65
-
-
0030842478
-
The yeast SWI-SNF complex facilitates binding of a transcriptional activator to nucleosomal sites in vivo
-
Burns, L.G. & Peterson, C.L. (1997). The yeast SWI-SNF complex facilitates binding of a transcriptional activator to nucleosomal sites in vivo. Mol. Cell. Biol. 17, 4811-4819.
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 4811-4819
-
-
Burns, L.G.1
Peterson, C.L.2
-
66
-
-
0030024412
-
DNA-binding properties of the SWI/SNF complex
-
Quinn, J., Fyrberg, A.M., Ganster, R.W., Schmidt, M.C. & Peterson, C.L. (1996). DNA-binding properties of the SWI/SNF complex. Nature 379, 844-847.
-
(1996)
Nature
, vol.379
, pp. 844-847
-
-
Quinn, J.1
Fyrberg, A.M.2
Ganster, R.W.3
Schmidt, M.C.4
Peterson, C.L.5
-
67
-
-
0028467446
-
Stimulation of GAL4 derivative binding to nucleosomal DNA by the yeast SWI/SNF complex
-
Cote, J., Quinn, J., Workman, J.L. & Peterson, C.L. (1994). Stimulation of GAL4 derivative binding to nucleosomal DNA by the yeast SWI/SNF complex. Science 265, 53-60.
-
(1994)
Science
, vol.265
, pp. 53-60
-
-
Cote, J.1
Quinn, J.2
Workman, J.L.3
Peterson, C.L.4
-
68
-
-
0028093378
-
Nucleosome disruption and enhancement of activator binding by a human SWI/SNF complex
-
Kwon, H., Imbalzano, A.N., Khaviri, P.A., Kingston, R.E. & Green, M.R. (1994). Nucleosome disruption and enhancement of activator binding by a human SWI/SNF complex. Nature 370, 477-481.
-
(1994)
Nature
, vol.370
, pp. 477-481
-
-
Kwon, H.1
Imbalzano, A.N.2
Khaviri, P.A.3
Kingston, R.E.4
Green, M.R.5
-
69
-
-
0026645025
-
Genetic isolation of ADA2: A potential transcriptional adaptor required for function of certain acidic actviation domains
-
Berger, S.L., et al. & Guarente, L. (1992). Genetic isolation of ADA2: a potential transcriptional adaptor required for function of certain acidic actviation domains. Cell 70, 251-265.
-
(1992)
Cell
, vol.70
, pp. 251-265
-
-
Berger, S.L.1
Guarente, L.2
-
70
-
-
0031031755
-
Histone acetyltransferase activity and interaction with ADA2 are critical for GCN5 function in vivo
-
Candau, R., Zhou, J.X., Allis, C.D. & Berger, S.L. (1997). Histone acetyltransferase activity and interaction with ADA2 are critical for GCN5 function in vivo. EMBO J. 16, 555-565.
-
(1997)
EMBO J.
, vol.16
, pp. 555-565
-
-
Candau, R.1
Zhou, J.X.2
Allis, C.D.3
Berger, S.L.4
-
71
-
-
0030447943
-
The TAFII250 subunit of TFIID has histone acetyltransferase activity
-
Mizzen, C.A., et al., & Allis, C.D. (1996). The TAFII250 subunit of TFIID has histone acetyltransferase activity. Cell 87, 1261-1270.
-
(1996)
Cell
, vol.87
, pp. 1261-1270
-
-
Mizzen, C.A.1
Allis, C.D.2
-
72
-
-
0030033699
-
RNA polymerase II holoenzyme contains Swi/Snf regulator involved in chromatin remodeling
-
Wilson, C.J., et al. & Roung, R.A. (1996). RNA polymerase II holoenzyme contains Swi/Snf regulator involved in chromatin remodeling. Cell 84, 235-244.
-
(1996)
Cell
, vol.84
, pp. 235-244
-
-
Wilson, C.J.1
Roung, R.A.2
-
73
-
-
0027411327
-
Synergism in transcriptional activation: A kinetic view
-
Herschlag, D. & Johnson, F.B. (1992). Synergism in transcriptional activation: a kinetic view. Genes Dev. 7, 173-179.
-
(1992)
Genes Dev.
, vol.7
, pp. 173-179
-
-
Herschlag, D.1
Johnson, F.B.2
-
74
-
-
0031310825
-
The mechanism of transcriptional synergy of an in vitro assembled interferon-β enhanceosome
-
Kim, T.K. & Maniatis, T. (1997). The mechanism of transcriptional synergy of an in vitro assembled interferon-β enhanceosome. Mol. Cell 1, 119-129.
-
(1997)
Mol. Cell
, vol.1
, pp. 119-129
-
-
Kim, T.K.1
Maniatis, T.2
-
75
-
-
0028986250
-
Assembly and function of a TCRα enhancer complex is dependent on LEF-1-induced DNA bending and multiple protein-protein interactions
-
Giese, K., Kingsley, C., Kirshner, J.R. & Grosschedl, R. (1995). Assembly and function of a TCRα enhancer complex is dependent on LEF-1-induced DNA bending and multiple protein-protein interactions. Genes Dev. 9, 995-1008.
-
(1995)
Genes Dev.
, vol.9
, pp. 995-1008
-
-
Giese, K.1
Kingsley, C.2
Kirshner, J.R.3
Grosschedl, R.4
-
76
-
-
0032540267
-
A calcineurin-dependent transcriptional pathway for cardiac hypertrophy
-
Molkentin, J.D., et al. & Olson, E.N. (1998). A calcineurin-dependent transcriptional pathway for cardiac hypertrophy. Cell 93, 215-228.
-
(1998)
Cell
, vol.93
, pp. 215-228
-
-
Molkentin, J.D.1
Olson, E.N.2
-
77
-
-
0030990201
-
Design of sequence-specific DNA-binding ligands
-
Nielsen, P.E. (1997). Design of sequence-specific DNA-binding ligands. Chem. Eur. J. 3, 505-508.
-
(1997)
Chem. Eur. J.
, vol.3
, pp. 505-508
-
-
Nielsen, P.E.1
-
78
-
-
0029759689
-
Biochemical evidence that a D-loop is part of a four-stranded PNA-DNA bundle. Nickel-mediated cleavage of duplex DNA by a Gly-Gly-His-Bis-PNA
-
Footer, M., Egholm, M., Kron, S., Coull, J.M. & Matsudaira, P. (1996). Biochemical evidence that a D-loop is part of a four-stranded PNA-DNA bundle. Nickel-mediated cleavage of duplex DNA by a Gly-Gly-His-Bis-PNA. Biochemistry 35, 10673-10679.
-
(1996)
Biochemistry
, vol.35
, pp. 10673-10679
-
-
Footer, M.1
Egholm, M.2
Kron, S.3
Coull, J.M.4
Matsudaira, P.5
-
79
-
-
0031979354
-
Antisense inhibition of gene expression in bacteria by PNA targeted to mRNA
-
Good, L. & Nielsen, P.E. (1998). Antisense inhibition of gene expression in bacteria by PNA targeted to mRNA. Nat. Biotechnol. 16, 355-358.
-
(1998)
Nat. Biotechnol.
, vol.16
, pp. 355-358
-
-
Good, L.1
Nielsen, P.E.2
-
80
-
-
0031959657
-
Genetic engineering of proteins with cell membrane permeability
-
Rojas, M., Donahue, J.P., Tan, Z. & Lin, Y.-Z. (1998). Genetic engineering of proteins with cell membrane permeability. Nat. Biotechnol. 16, 370-375.
-
(1998)
Nat. Biotechnol.
, vol.16
, pp. 370-375
-
-
Rojas, M.1
Donahue, J.P.2
Tan, Z.3
Lin, Y.-Z.4
-
81
-
-
0029786013
-
Recognition of DNA by designed ligands at subnanomolar concentrations
-
Trauger, J.W., Baird, E.E. & Dervan, P.B. (1996). Recognition of DNA by designed ligands at subnanomolar concentrations. Nature 382, 559-561.
-
(1996)
Nature
, vol.382
, pp. 559-561
-
-
Trauger, J.W.1
Baird, E.E.2
Dervan, P.B.3
-
82
-
-
0026556818
-
Rational design of tripyrrole peptides that complex DNA by both selective minor groove binding and electrostatic interaction with the phosphate
-
Bruice, T.C., Mei, H.-Y., He, G.-X. & Lopez, V. (1992). Rational design of tripyrrole peptides that complex DNA by both selective minor groove binding and electrostatic interaction with the phosphate. Proc. Natl Acad. Sci. USA 89, 1700-1704.
-
(1992)
Proc. Natl Acad. Sci. USA
, vol.89
, pp. 1700-1704
-
-
Bruice, T.C.1
Mei, H.-Y.2
He, G.-X.3
Lopez, V.4
-
83
-
-
0030961783
-
Targeting E2F1-DNA complexes with microgonotropen DNA binding agents
-
Chiang, S.-Y., Bruice, T.C., Azizkhan, J.C., Gawron, L. & Beerman, T.A. (1997). Targeting E2F1-DNA complexes with microgonotropen DNA binding agents. Proc. Natl Sci. USA 94, 2811-2816.
-
(1997)
Proc. Natl Sci. USA
, vol.94
, pp. 2811-2816
-
-
Chiang, S.-Y.1
Bruice, T.C.2
Azizkhan, J.C.3
Gawron, L.4
Beerman, T.A.5
-
84
-
-
0026661689
-
Antiparallel side-by-side dimeric motif for sequence-specific recognition in the minor groove of DNA by the designed peptide 1-methylimidazole-2-carboxamide netropsin
-
Mrksich, M., et al. & Wemmer, D.E. (1992). Antiparallel side-by-side dimeric motif for sequence-specific recognition in the minor groove of DNA by the designed peptide 1-methylimidazole-2-carboxamide netropsin. Proc. Natl. Acad. Sci. USA 89, 7586-7590.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 7586-7590
-
-
Mrksich, M.1
Wemmer, D.E.2
-
85
-
-
0028171224
-
Design of a G.C-specific DNA minor groove-binding peptide
-
Geierstanger, B.H., Mrksich, M., Dervan, P.B. & Wemmer, D.E. (1994). Design of a G.C-specific DNA minor groove-binding peptide. Science 266, 646-650.
-
(1994)
Science
, vol.266
, pp. 646-650
-
-
Geierstanger, B.H.1
Mrksich, M.2
Dervan, P.B.3
Wemmer, D.E.4
-
86
-
-
0032576722
-
Recognition of the four Watson-Crick base pairs in the DNA minor groove by synthetic ligands
-
White, S., Szewczyk, J.W., Turner, J.M., Baird, E.E. & Dervan, P.B. (1998). Recognition of the four Watson-Crick base pairs in the DNA minor groove by synthetic ligands. Nature 391, 468-471.
-
(1998)
Nature
, vol.391
, pp. 468-471
-
-
White, S.1
Szewczyk, J.W.2
Turner, J.M.3
Baird, E.E.4
Dervan, P.B.5
-
88
-
-
0031215078
-
On the pairing rules in the minor groove of DNA by pyrrole-imidazole polyamides
-
White, S., Baird, E.E. & Dervan, P.B. (1997). On the pairing rules in the minor groove of DNA by pyrrole-imidazole polyamides. Chem. Biol. 4, 569-578.
-
(1997)
Chem. Biol.
, vol.4
, pp. 569-578
-
-
White, S.1
Baird, E.E.2
Dervan, P.B.3
-
89
-
-
0030951207
-
Regulation of gene expression by small molecules
-
Gottesfeld, J.M., Neely, L., Trauger, J.W., Baird, E.E. & Dervan, P.B. (1997). Regulation of gene expression by small molecules. Nature 387, 202-205.
-
(1997)
Nature
, vol.387
, pp. 202-205
-
-
Gottesfeld, J.M.1
Neely, L.2
Trauger, J.W.3
Baird, E.E.4
Dervan, P.B.5
-
90
-
-
0032033739
-
Inhibition of major groove-binding proteins by pyrrole-imidazole polyamides with an Arg-Pro-Arg patch
-
Bremer, R.E., Baird, E.E. & Dervan, P.B. (1998). Inhibition of major groove-binding proteins by pyrrole-imidazole polyamides with an Arg-Pro-Arg patch. Chem. Biol. 5, 119-133.
-
(1998)
Chem. Biol.
, vol.5
, pp. 119-133
-
-
Bremer, R.E.1
Baird, E.E.2
Dervan, P.B.3
-
91
-
-
0027049805
-
The GCN4 basic region leucine zipper binds DNA as a dimer of uninterrupted helices
-
Ellenberger, T.E., Brandl, C.J., Struhl, K. & Harrison, S.C. (1992). The GCN4 basic region leucine zipper binds DNA as a dimer of uninterrupted helices. Cell 71, 1223-1237.
-
(1992)
Cell
, vol.71
, pp. 1223-1237
-
-
Ellenberger, T.E.1
Brandl, C.J.2
Struhl, K.3
Harrison, S.C.4
-
92
-
-
0026325168
-
TFIID binds in the minor groove of the TATA box
-
Starr, D.B. & Hawley, D.K. (1991). TFIID binds in the minor groove of the TATA box. Cell 67, 1231-1240.
-
(1991)
Cell
, vol.67
, pp. 1231-1240
-
-
Starr, D.B.1
Hawley, D.K.2
-
93
-
-
0024326749
-
Functional distinctions between yeast TATA elements
-
Harbury, P.A.B. & Struhl, K. (1989). Functional distinctions between yeast TATA elements. Mol. Cell. Biol. 9, 5298-5304.
-
(1989)
Mol. Cell. Biol.
, vol.9
, pp. 5298-5304
-
-
Harbury, P.A.B.1
Struhl, K.2
-
94
-
-
0028136464
-
Specific inhibition of formation of transcription complexes by a calicheamicin oligosaccharide: A paradigm for the development of transcriptional antagonists
-
Ho, S.N., Boyer, S.H., Schreiber, S.L., Danishefsky, S.J. & Crabtree, G.R. (1994). Specific inhibition of formation of transcription complexes by a calicheamicin oligosaccharide: a paradigm for the development of transcriptional antagonists. Proc. Natl Acad. Sci. USA 91, 9203-9207.
-
(1994)
Proc. Natl Acad. Sci. USA
, vol.91
, pp. 9203-9207
-
-
Ho, S.N.1
Boyer, S.H.2
Schreiber, S.L.3
Danishefsky, S.J.4
Crabtree, G.R.5
-
95
-
-
0029141654
-
Strategies for the design of minor groove binders: A re-evaluation based on the emergence of site-selective carbohydrate binders
-
Kahne, D. (1995). Strategies for the design of minor groove binders: a re-evaluation based on the emergence of site-selective carbohydrate binders. Chem. Biol. 2, 7-12.
-
(1995)
Chem. Biol.
, vol.2
, pp. 7-12
-
-
Kahne, D.1
-
96
-
-
0024406857
-
A novel genetic system to detect protein-protein interactions
-
Fields, S. & Song, O.-k. (1989). A novel genetic system to detect protein-protein interactions. Nature 340, 245-246.
-
(1989)
Nature
, vol.340
, pp. 245-246
-
-
Fields, S.1
Song, O.-K.2
-
97
-
-
0028856072
-
The activation domain of GAL4 protein mediates cooperative promoter binding with general transcription factors in vivo
-
Vashee, S. & Kodadek, T. (1995). The activation domain of GAL4 protein mediates cooperative promoter binding with general transcription factors in vivo. Proc. Natl Acad. Sci. USA 92, 10683-10687.
-
(1995)
Proc. Natl Acad. Sci. USA
, vol.92
, pp. 10683-10687
-
-
Vashee, S.1
Kodadek, T.2
-
98
-
-
0032499071
-
Evidence for two modes of cooperative DNA binding in vivo that do not involve direct protein-protein interactions
-
Vashee, S., Melcher, K., Ding, W.V., Johnston, S.A. & Kodadek, T. (1998). Evidence for two modes of cooperative DNA binding in vivo that do not involve direct protein-protein interactions. Curr. Biol. 8, 452-458.
-
(1998)
Curr. Biol.
, vol.8
, pp. 452-458
-
-
Vashee, S.1
Melcher, K.2
Ding, W.V.3
Johnston, S.A.4
Kodadek, T.5
-
99
-
-
0028926048
-
Protein-protein interactions: Methods for detection and analysis
-
Phizicky, E.M. & Fields, S. (1995). Protein-protein interactions: Methods for detection and analysis. Microb. Rev. 59, 94-123.
-
(1995)
Microb. Rev.
, vol.59
, pp. 94-123
-
-
Phizicky, E.M.1
Fields, S.2
-
100
-
-
0029824170
-
A three-hybrid system for detecting small ligand-protein interactions
-
Lecitra, EJ. & Liu, J.O. (1996). A three-hybrid system for detecting small ligand-protein interactions. Proc. Natl Acad. Sci. USA 93, 12817-12821.
-
(1996)
Proc. Natl Acad. Sci. USA
, vol.93
, pp. 12817-12821
-
-
Lecitra, E.J.1
Liu, J.O.2
-
101
-
-
0029840668
-
Genetic characterization of a mammalian protein-protein interaction domain by using a yeast reverse two-hybrid system
-
Vidai, M., Braun, P., Chen, E., Boeke, J.D. & Harlow, E. (1996). Genetic characterization of a mammalian protein-protein interaction domain by using a yeast reverse two-hybrid system. Proc. Natl Acad. Sci. USA 93, 10321-10326.
-
(1996)
Proc. Natl Acad. Sci. USA
, vol.93
, pp. 10321-10326
-
-
Vidai, M.1
Braun, P.2
Chen, E.3
Boeke, J.D.4
Harlow, E.5
-
102
-
-
0029789732
-
The reverse two-hybrid system: A genetic scheme for selection against specific protein/protein interactions
-
Leanna, C.A. & Hannink, M. (1996). The reverse two-hybrid system: a genetic scheme for selection against specific protein/protein interactions. Nucleic Acids Res. 24, 3341-3347.
-
(1996)
Nucleic Acids Res.
, vol.24
, pp. 3341-3347
-
-
Leanna, C.A.1
Hannink, M.2
-
103
-
-
0031472251
-
A yeast genetic system for selecting small molecule inhibitors of protein-protein interactions in nanodroplets
-
Huang, J. & Schreiber, S.L. (1997). A yeast genetic system for selecting small molecule inhibitors of protein-protein interactions in nanodroplets. Proc. Natl Acad. Sci. USA 94, 13396-13401.
-
(1997)
Proc. Natl Acad. Sci. USA
, vol.94
, pp. 13396-13401
-
-
Huang, J.1
Schreiber, S.L.2
-
104
-
-
0025598302
-
Sequence requirements for coiled-coils: Analysis with λ repressor-GCN4 leucine zipper fusions
-
Hu, J., O'Shea, E.K., Kim, P.S. & Sauer, R.T. (1990). Sequence requirements for coiled-coils: Analysis with λ repressor-GCN4 leucine zipper fusions. Science 250, 1400-1403.
-
(1990)
Science
, vol.250
, pp. 1400-1403
-
-
Hu, J.1
O'Shea, E.K.2
Kim, P.S.3
Sauer, R.T.4
-
105
-
-
0002201599
-
Combinatorial chemistry
-
Borman, S. (1997). Combinatorial chemistry. Chem. Eng. News 75, 43-62.
-
(1997)
Chem. Eng. News
, vol.75
, pp. 43-62
-
-
Borman, S.1
-
106
-
-
0031444011
-
Small molecule-dependent genetic selection in stochastic nanodroplets as a means of detecting protein-ligand interactions on a large scale
-
Borchardt, A., Liberles, S.D., Biggar, S.R., Crabtree, G.R. & Schreiber, S.L. (1997). Small molecule-dependent genetic selection in stochastic nanodroplets as a means of detecting protein-ligand interactions on a large scale. Chem. Biol. 4, 961-968.
-
(1997)
Chem. Biol.
, vol.4
, pp. 961-968
-
-
Borchardt, A.1
Liberles, S.D.2
Biggar, S.R.3
Crabtree, G.R.4
Schreiber, S.L.5
-
107
-
-
0031472576
-
A miniaturized arrayed assay format for detecting small molecule-protein interactions in cells
-
You, A.J., Jackman, R.J., Whitesides, G.M. & Schreiber, S.L. (1997). A miniaturized arrayed assay format for detecting small molecule-protein interactions in cells. Chem. Biol. 4, 969-975.
-
(1997)
Chem. Biol.
, vol.4
, pp. 969-975
-
-
You, A.J.1
Jackman, R.J.2
Whitesides, G.M.3
Schreiber, S.L.4
-
108
-
-
0029315510
-
Tumour suppressors, kinases and clamps: How p53 regulates the cell cycle in response to DNA damage
-
Cox, L.S. & Lane, O.P. (1995). Tumour suppressors, kinases and clamps: how p53 regulates the cell cycle in response to DNA damage. Bioessays 17, 501-508.
-
(1995)
Bioessays
, vol.17
, pp. 501-508
-
-
Cox, L.S.1
Lane, O.P.2
-
109
-
-
0031439518
-
A nonnatural transcriptional coactivator
-
Nyanguile, O. Uesugi, M. Austin, D.J. & Verdine, G.L. (1997). A nonnatural transcriptional coactivator. Proc. Natl Acad. Sci. USA 94, 13402-13406.
-
(1997)
Proc. Natl Acad. Sci. USA
, vol.94
, pp. 13402-13406
-
-
Nyanguile, O.1
Uesugi, M.2
Austin, D.J.3
Verdine, G.L.4
-
110
-
-
0031881688
-
The Med proteins of yeast and their function through the RNA polymerase II carboxy-terminal domain
-
Myers, L.C., et al. & Kornberg, R.D. (1998). The Med proteins of yeast and their function through the RNA polymerase II carboxy-terminal domain. Genes Dev. 12, 45-54.
-
(1998)
Genes Dev.
, vol.12
, pp. 45-54
-
-
Myers, L.C.1
Kornberg, R.D.2
|