-
1
-
-
0031014830
-
Role of fatty acids in the pathogenesis of insulin resistance and NIDDM
-
Boden G: Role of fatty acids in the pathogenesis of insulin resistance and NIDDM. Diabetes 46:3-10, 1997
-
(1997)
Diabetes
, vol.46
, pp. 3-10
-
-
Boden, G.1
-
2
-
-
0026529589
-
Stimulation of lipolysis in cultured fat cells by tumor necrosisfactor, interleukin-1, and the interferons is blocked by inhibition of prostaglandin synthesis
-
Feingold KR, Doerrler W, Dinarello CA, Fiers W, Grunfeld C: Stimulation of lipolysis in cultured fat cells by tumor necrosisfactor, interleukin-1, and the interferons is blocked by inhibition of prostaglandin synthesis. Endocrinology 130:10-16, 1992
-
(1992)
Endocrinology
, vol.130
, pp. 10-16
-
-
Feingold, K.R.1
Doerrler, W.2
Dinarello, C.A.3
Fiers, W.4
Grunfeld, C.5
-
3
-
-
0028302002
-
Tumor necrosis factor increases the rate of lipolysis in primary cultures of adipocytes without altering levels of hormone-sensitive lipase
-
Green A, Dobias SB, Walters DJA, Brasier AR: Tumor necrosis factor increases the rate of lipolysis in primary cultures of adipocytes without altering levels of hormone-sensitive lipase. Endocrinology 134:2581-2588, 1994
-
(1994)
Endocrinology
, vol.134
, pp. 2581-2588
-
-
Green, A.1
Dobias, S.B.2
Walters, D.J.A.3
Brasier, A.R.4
-
4
-
-
0029041905
-
Effects of tumor necrosis factor alpha (TNFα) on glucose transport and lipid metabolism of newly differentiated human fat cells in cell culture
-
Hauner H, Petruschke T, Russ M, Rohrig K, Eckel J: Effects of tumor necrosis factor alpha (TNFα) on glucose transport and lipid metabolism of newly differentiated human fat cells in cell culture. Diabetologia 38:764-771, 1995
-
(1995)
Diabetologia
, vol.38
, pp. 764-771
-
-
Hauner, H.1
Petruschke, T.2
Russ, M.3
Rohrig, K.4
Eckel, J.5
-
5
-
-
0023129921
-
Human recombinant TNF suppresses lipoprotein lipase activity and stimulates lipolysis in 3T3-L 1 cells
-
Kawakami M, Murase T, Ogawa H, Ishibashi S, Mori N, Takaku F, Shibata S: Human recombinant TNF suppresses lipoprotein lipase activity and stimulates lipolysis in 3T3-L1 cells. J Biochem 101:331-338, 1987
-
(1987)
J Biochem
, vol.101
, pp. 331-338
-
-
Kawakami, M.1
Murase, T.2
Ogawa, H.3
Ishibashi, S.4
Mori, N.5
Takaku, F.6
Shibata, S.7
-
6
-
-
0031948947
-
BRL 49653 blocks the lipolytic actions of tumor necrosis factor-α: A potential new insulin-sensitizing mechanism for the thiazolidinediones
-
Souza SC, Yamamoto MT, Franciosa MD, Lien P, Greenberg AS: BRL 49653 blocks the lipolytic actions of tumor necrosis factor-α: a potential new insulin-sensitizing mechanism for the thiazolidinediones. Diabetes 47:691-695, 1998
-
(1998)
Diabetes
, vol.47
, pp. 691-695
-
-
Souza, S.C.1
Yamamoto, M.T.2
Franciosa, M.D.3
Lien, P.4
Greenberg, A.S.5
-
7
-
-
0028931724
-
Increased adipose tissue expression of tumor necrosis factor-α in human obesity and insulin resistance
-
Hotamisligil GS, Arner P, Caro JF, Atkinson RL, Spiegelman BM: Increased adipose tissue expression of tumor necrosis factor-α in human obesity and insulin resistance. J Clin Invest 95:2409-2415, 1995
-
(1995)
J Clin Invest
, vol.95
, pp. 2409-2415
-
-
Hotamisligil, G.S.1
Arner, P.2
Caro, J.F.3
Atkinson, R.L.4
Spiegelman, B.M.5
-
8
-
-
0027459878
-
Adipose expression of tumor necrosis factor-α: Direct role in obesity-linked insulin resistance
-
Hotamisligil GS, Shargill NS, Spiegelman BM: Adipose expression of tumor necrosis factor-α: direct role in obesity-linked insulin resistance. Science 259:87-91, 1993
-
(1993)
Science
, vol.259
, pp. 87-91
-
-
Hotamisligil, G.S.1
Shargill, N.S.2
Spiegelman, B.M.3
-
9
-
-
0035023128
-
Adipose tissue tumor necrosis factor and interleukin-6 expression in human obesity and insulin resistance
-
Kern P, Ranganathan S, Wood L, Ranganathan G: Adipose tissue tumor necrosis factor and interleukin-6 expression in human obesity and insulin resistance. Am J Physiol Endocrinol Metab 280:E745-E751, 2001
-
(2001)
Am J Physiol Endocrinol Metab
, vol.280
-
-
Kern, P.1
Ranganathan, S.2
Wood, L.3
Ranganathan, G.4
-
10
-
-
0028968879
-
The expression of tumor necrosis factor in human adipose tissue: Regulation by obesity, weight loss, and relationship to lipoprotein lipase
-
Kern PA, Saghizadeh M, Ong JM, Bosch RJ, Deem R, Simsolo RB: The expression of tumor necrosis factor in human adipose tissue: regulation by obesity, weight loss, and relationship to lipoprotein lipase. J Clin Invest 95:2111-2119, 1995
-
(1995)
J Clin Invest
, vol.95
, pp. 2111-2119
-
-
Kern, P.A.1
Saghizadeh, M.2
Ong, J.M.3
Bosch, R.J.4
Deem, R.5
Simsolo, R.B.6
-
11
-
-
0033304608
-
The differential effect of food intake and β-adrenergic stimulation on adipose-derived hormones and cytokines in man
-
Orban Z, Remaley A, Sampson M, Trajanoski Z, Chrousos G: The differential effect of food intake and β-adrenergic stimulation on adipose-derived hormones and cytokines in man. J Clin Endocrinol Metab 84:2126-2133, 1999
-
(1999)
J Clin Endocrinol Metab
, vol.84
, pp. 2126-2133
-
-
Orban, Z.1
Remaley, A.2
Sampson, M.3
Trajanoski, Z.4
Chrousos, G.5
-
12
-
-
0026560336
-
Acute administration of tumor necrosis factor-alpha or interleukin-1 does not mimic the hypoketonaemia associated with sepsis and inflammatory stress in the rat
-
Evans R, Illic V, Williamson D: Acute administration of tumor necrosis factor-alpha or interleukin-1 does not mimic the hypoketonaemia associated with sepsis and inflammatory stress in the rat. Clin Sci 82:205-209, 1992
-
(1992)
Clin Sci
, vol.82
, pp. 205-209
-
-
Evans, R.1
Illic, V.2
Williamson, D.3
-
13
-
-
0023757088
-
Tumor necrosis factor and the acute metabolic response to tissue injury in man
-
Starnes HF, Warren R, Jeevanandam M, Gabriliove J, Larchian W, Oettgen H, Brennan M: Tumor necrosis factor and the acute metabolic response to tissue injury in man. J Clin Invest 82:1321-1325, 1988
-
(1988)
J Clin Invest
, vol.82
, pp. 1321-1325
-
-
Starnes, H.F.1
Warren, R.2
Jeevanandam, M.3
Gabriliove, J.4
Larchian, W.5
Oettgen, H.6
Brennan, M.7
-
14
-
-
0026075959
-
Tumor necrosis factor mimics the metabolic response to acute infection in healthy humans
-
Van Der Poll T, Romijn J, Endert E, Borm J, Buller H, Sauerwein H: Tumor necrosis factor mimics the metabolic response to acute infection in healthy humans. Am J Physiol 261:E457-E465, 1991
-
(1991)
Am J Physiol
, vol.261
-
-
Van Der Poll, T.1
Romijn, J.2
Endert, E.3
Borm, J.4
Buller, H.5
Sauerwein, H.6
-
15
-
-
0030756346
-
Protection from obesity-linked insulin resistance in mice lacking TNF-α function
-
Uysal K, Wiesbrock S, Marino M, Hotamisligil GS: Protection from obesity-linked insulin resistance in mice lacking TNF-α function. Nature 389:610-614, 1997
-
(1997)
Nature
, vol.389
, pp. 610-614
-
-
Uysal, K.1
Wiesbrock, S.2
Marino, M.3
Hotamisligil, G.S.4
-
16
-
-
4243608452
-
TNF-α increases lipolysis through activation of ERK and JNK1 MAP kinase pathways in 3T3-L1 adipocytes
-
Souza S, Palmer H, Lien P, Paulson K: TNF-α increases lipolysis through activation of ERK and JNK1 MAP kinase pathways in 3T3-L1 adipocytes (Abstract). Diabetes 47(Suppl. 1):A338, 1998
-
(1998)
Diabetes
, vol.47
, Issue.SUPPL. 1
-
-
Souza, S.1
Palmer, H.2
Lien, P.3
Paulson, K.4
-
17
-
-
0032969285
-
Tumor necrosis factor receptor and Fas signaling mechanisms
-
Wallach D, Varfolomeev E, Malini N, Goltsev Y, Kovalenko A, Boldin M: Tumor necrosis factor receptor and Fas signaling mechanisms. Annu Rev Immunology 17:331-367, 1999
-
(1999)
Annu Rev Immunology
, vol.17
, pp. 331-367
-
-
Wallach, D.1
Varfolomeev, E.2
Malini, N.3
Goltsev, Y.4
Kovalenko, A.5
Boldin, M.6
-
18
-
-
0033773334
-
Tumor necrosis factor-α-mediated insulin resistance, but not dedifferentiation, is abrogated by MEK1/2 inhibitors in 3T3-L 1 adipocytes
-
Engelman JA, Berg AH, Lewis RY, Lisanti MP, Scherer PE: Tumor necrosis factor-α-mediated insulin resistance, but not dedifferentiation, is abrogated by MEK1/2 inhibitors in 3T3-L1 adipocytes. Mol Endocrinol 14:1557-1569, 2000
-
(2000)
Mol Endocrinol
, vol.14
, pp. 1557-1569
-
-
Engelman, J.A.1
Berg, A.H.2
Lewis, R.Y.3
Lisanti, M.P.4
Scherer, P.E.5
-
19
-
-
0035976955
-
Stimulation of lipolysis and hormone-sensitive lipase via the extracellular signal related kinase pathway
-
454456-445461
-
Greenberg A, Shen W, Muliro K, Patel S, Souza S, Roth R, Kraemer F: Stimulation of lipolysis and hormone-sensitive lipase via the extracellular signal related kinase pathway. J Biol Chem 276:454456-445461, 2001
-
(2001)
J Biol Chem
, vol.276
-
-
Greenberg, A.1
Shen, W.2
Muliro, K.3
Patel, S.4
Souza, S.5
Roth, R.6
Kraemer, F.7
-
20
-
-
0034623950
-
Perilipin A increases triacylglycerol storage by decreasing the rate of triacylglycerol hydrolysis
-
Brasaemle D, Rubin B, Harten I, Gruia-Gray J, Kimmel A, Londos C: Perilipin A increases triacylglycerol storage by decreasing the rate of triacylglycerol hydrolysis. J Biol Chem 275:38486-38493, 2000
-
(2000)
J Biol Chem
, vol.275
, pp. 38486-38493
-
-
Brasaemle, D.1
Rubin, B.2
Harten, I.3
Gruia-Gray, J.4
Kimmel, A.5
Londos, C.6
-
21
-
-
0025772167
-
Perilipin, a major hormonally regulated adipocyte-specific phosphoprotein associated with the periphery of the lipid storage droplets
-
Greenberg A, Egan J, Wek S, Garty NEJ, Blanchette-Mackie E, Londos C: Perilipin, a major hormonally regulated adipocyte-specific phosphoprotein associated with the periphery of the lipid storage droplets. J Biol Chem 266:11341-11346, 1991
-
(1991)
J Biol Chem
, vol.266
, pp. 11341-11346
-
-
Greenberg, A.1
Egan, J.2
Wek, S.3
Garty, N.E.J.4
Blanchette-Mackie, E.5
Londos, C.6
-
22
-
-
0033671833
-
db/db mice
-
db/db mice. Nat Genet 26:474-479, 2000
-
(2000)
Nat Genet
, vol.26
, pp. 474-479
-
-
Martinez-Botas, J.1
Andreson, J.2
Tessler, D.3
Lapillojnne, A.4
Hung-Junn Chang, B.5
Quast, M.6
Gorenstein, D.7
Chen, K.-H.8
Chan, L.9
-
23
-
-
0032544690
-
Overexpression of perilipin A and B blocks the ability of tumor necrosis factor to increase adipocyte lipolysis in 3T3-L 1 adipocytes
-
Souza S, Moitoso de Vargas L, Yamamato M, Line P, Franciosa M, Moss L, Greenberg A: Overexpression of perilipin A and B blocks the ability of tumor necrosis factor to increase adipocyte lipolysis in 3T3-L1 adipocytes. J Biol Chem 273:24665-24669, 1998
-
(1998)
J Biol Chem
, vol.273
, pp. 24665-24669
-
-
Souza, S.1
Moitoso de Vargas, L.2
Yamamato, M.3
Line, P.4
Franciosa, M.5
Moss, L.6
Greenberg, A.7
-
24
-
-
0037040911
-
Modulation of hormone-sensitive lipase and protein kinase-A-mediated lipolysis by perilipin A in an adenoviral reconstituted system
-
Souza S, Muliro K, Liscum L, Lien P, Yamamoto Y, Schaffer J, Dallal G, Wang X, Kraemer F, Obin M, Greenberg A: Modulation of hormone-sensitive lipase and protein kinase-A-mediated lipolysis by perilipin A in an adenoviral reconstituted system. J Biol Chem 277:8267-8272, 2001
-
(2001)
J Biol Chem
, vol.277
, pp. 8267-8272
-
-
Souza, S.1
Muliro, K.2
Liscum, L.3
Lien, P.4
Yamamoto, Y.5
Schaffer, J.6
Dallal, G.7
Wang, X.8
Kraemer, F.9
Obin, M.10
Greenberg, A.11
-
25
-
-
14344268795
-
Perilipin ablation results in a lean mouse with aberrant adipocyte lipolysis, enhanced leptin production, and resistance to diet-induced obesity
-
Tansey J, Sztalryd C, Gruia-Gray J, Roush D, Zeo J, Gavrilova O, Reitman M, Deng, C-X, Ki C, Kimmel A, Londos C: Perilipin ablation results in a lean mouse with aberrant adipocyte lipolysis, enhanced leptin production, and resistance to diet-induced obesity. Proc Natl Acad Sci U S A 98:6494-6499, 2001
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 6494-6499
-
-
Tansey, J.1
Sztalryd, C.2
Gruia-Gray, J.3
Roush, D.4
Zeo, J.5
Gavrilova, O.6
Reitman, M.7
Deng, C.-X.8
Ki, C.9
Kimmel, A.10
Londos, C.11
-
26
-
-
0034681341
-
Translocation of hormone-sensitive lipase and perilipin upon lipolytic stimulation of rat adipocytes
-
Clifford G, Londos C, Kraemer F, Vernon R, Yeaman S: Translocation of hormone-sensitive lipase and perilipin upon lipolytic stimulation of rat adipocytes. J Biol Chem 275:5011-5015, 2000
-
(2000)
J Biol Chem
, vol.275
, pp. 5011-5015
-
-
Clifford, G.1
Londos, C.2
Kraemer, F.3
Vernon, R.4
Yeaman, S.5
-
27
-
-
0033071156
-
Perilipins ADRP and other proteins that associate with intracellular neutral lipid droplets in animal cells
-
Londos C, Brasaemle D, Schultz C, Segrest J, Kimmel A: Perilipins ADRP, and other proteins that associate with intracellular neutral lipid droplets in animal cells. Semin Cell Dev Biol 10:51-58, 1999
-
(1999)
Semin Cell Dev Biol
, vol.10
, pp. 51-58
-
-
Londos, C.1
Brasaemle, D.2
Schultz, C.3
Segrest, J.4
Kimmel, A.5
-
28
-
-
0034161845
-
Downregulation of cyclic nucleotide phosphodiesterase 3B in 3T3-L1 adipocytes induced by tumor necrosis factor α and cAMP
-
Landstrom R, Mie J, Karlsson M, Manganiello V, Degereman E: Downregulation of cyclic nucleotide phosphodiesterase 3B in 3T3-L1 adipocytes induced by tumor necrosis factor α and cAMP. Biochem J 346:337-343, 2000
-
(2000)
Biochem J
, vol.346
, pp. 337-343
-
-
Landstrom, R.1
Mie, J.2
Karlsson, M.3
Manganiello, V.4
Degereman, E.5
-
29
-
-
78651166782
-
Metabolism of isolated fat cells-effect of hormones on glucose metabolism and lipolysis
-
Rodbell M: Metabolism of isolated fat cells-effect of hormones on glucose metabolism and lipolysis. J Biol Chem 239:375-380, 1964
-
(1964)
J Biol Chem
, vol.239
, pp. 375-380
-
-
Rodbell, M.1
-
30
-
-
0030872062
-
Ras-dependent mitogen-activated protein kinase activation by G protein coupled receptors: Convergence of Gi- and Gq-mediated pathways on calcium, calmodulin, Pyk 2, and Src kinase
-
Della Rocca G, van Biesen T, Daaka Y, Luttrell D, Luttrell L, Lefkowitz R: Ras-dependent mitogen-activated protein kinase activation by G protein coupled receptors: convergence of Gi- and Gq-mediated pathways on calcium, calmodulin, Pyk2, and Src kinase. J Biol Chem 272:19125-19132, 1997
-
(1997)
J Biol Chem
, vol.272
, pp. 19125-19132
-
-
Della Rocca, G.1
Van Biesen, T.2
Daaka, Y.3
Luttrell, D.4
Luttrell, L.5
Lefkowitz, R.6
-
32
-
-
0029043582
-
How MAP kinases are regulated?
-
Cobb M, Goldsmith E: How MAP kinases are regulated? J Biol Chem 270:14843-14846, 1995
-
(1995)
J Biol Chem
, vol.270
, pp. 14843-14846
-
-
Cobb, M.1
Goldsmith, E.2
-
33
-
-
0027165150
-
The mitogen-activated protein kinase signal transduction pathway
-
Davis R: The mitogen-activated protein kinase signal transduction pathway. J Biol Chem 268:14553-14556, 1993
-
(1993)
J Biol Chem
, vol.268
, pp. 14553-14556
-
-
Davis, R.1
-
34
-
-
0028884033
-
PD 98059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo
-
Alessi D, Cuenda A, Cohen P, Dudley D, Saltiel A: PD 98059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo. J Biol Chem 70:27489-27494, 1995
-
(1995)
J Biol Chem
, vol.70
, pp. 27489-27494
-
-
Alessi, D.1
Cuenda, A.2
Cohen, P.3
Dudley, D.4
Saltiel, A.5
-
35
-
-
14444279192
-
Identification of a novel inhibitor of mitogen-activated protein kinase kinase
-
Favata M, Horiuchi K, Manos E, Daulerio A, Stradley D, Feeser W, Van Dyk D, Pitts W, Earl R, Hobbs F, Copeland R, Magolda R, Scherle P, Trzaskos J: Identification of a novel inhibitor of mitogen-activated protein kinase kinase. J Biol Chem 273:18623-18632, 1998
-
(1998)
J Biol Chem
, vol.273
, pp. 18623-18632
-
-
Favata, M.1
Horiuchi, K.2
Manos, E.3
Daulerio, A.4
Stradley, D.5
Feeser, W.6
Van Dyk, D.7
Pitts, W.8
Earl, R.9
Hobbs, F.10
Copeland, R.11
Magolda, R.12
Scherle, P.13
Trzaskos, J.14
-
36
-
-
0027233448
-
Signal transduction via the MAP kinases: Proceed at your own RSK
-
Blenis J: Signal transduction via the MAP kinases: proceed at your own RSK. Proc Natl Acad Sci U S A 90:5889-5892, 1993
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, pp. 5889-5892
-
-
Blenis, J.1
-
37
-
-
0038776380
-
Inhibition of adipogenesis through MAP kinase-mediated phosphorylation of PPARγ
-
Hu E, Kim JB, Sarraf P, Spiegelman B: Inhibition of adipogenesis through MAP kinase-mediated phosphorylation of PPARγ. Science 274:2100-2103, 1996
-
(1996)
Science
, vol.274
, pp. 2100-2103
-
-
Hu, E.1
Kim, J.B.2
Sarraf, P.3
Spiegelman, B.4
-
38
-
-
0029069574
-
Perilipin is located on the surface layer of the intracellular lipid droplets in adipocytes
-
Blanchette-Mackie EJ, Dwyer NK, Barber T, Coxey RA, Takeda T, Rondonine CM, Theodoraldas JL, Greenberg AS, Londos C: Perilipin is located on the surface layer of the intracellular lipid droplets in adipocytes. J Lipid Res 36:1211-1226, 1995
-
(1995)
J Lipid Res
, vol.36
, pp. 1211-1226
-
-
Blanchette-Mackie, E.J.1
Dwyer, N.K.2
Barber, T.3
Coxey, R.A.4
Takeda, T.5
Rondonine, C.M.6
Theodoraldas, J.L.7
Greenberg, A.S.8
Londos, C.9
-
39
-
-
0025131389
-
Control of endogenous phosphorylation of the major cAMP-dependent β-adrenergic stimulation
-
Egan JJ, Greenberg AS, Chang M-K, Londos C: Control of endogenous phosphorylation of the major cAMP-dependent β-adrenergic stimulation. J Biol Chem 265:18769-18775, 1990
-
(1990)
J Biol Chem
, vol.265
, pp. 18769-18775
-
-
Egan, J.J.1
Greenberg, A.S.2
Chang, M.-K.3
Londos, C.4
-
40
-
-
0027145164
-
Isolation of cDNAs for perilipins A and B: Sequence and expression of lipid droplet-associated proteins of adipocytes
-
Greenberg A, Egan J, Wek S, Moos J MC, Londos C, Kimmel A: Isolation of cDNAs for perilipins A and B: sequence and expression of lipid droplet-associated proteins of adipocytes. Proc Natl Acad Sci U S A 90: 12035-12039, 1993
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, pp. 12035-12039
-
-
Greenberg, A.1
Egan, J.2
Wek, S.3
Moos, J.M.C.4
Londos, C.5
Kimmel, A.6
-
41
-
-
2642614548
-
Identification of novel phosphorylation sites in hormone-sensitive lipase that are phosphorylated in response to isoproterenol and govern activation properties in vivo
-
Anthonsen M, Ronnstrand L, Wernstedt C, Degerman E, Holm C: Identification of novel phosphorylation sites in hormone-sensitive lipase that are phosphorylated in response to isoproterenol and govern activation properties in vivo. J Biol Chem 273:215-221, 1998
-
(1998)
J Biol Chem
, vol.273
, pp. 215-221
-
-
Anthonsen, M.1
Ronnstrand, L.2
Wernstedt, C.3
Degerman, E.4
Holm, C.5
-
42
-
-
0019481108
-
Hormone-sensitive lipase of rat adipose tissue: Purification and some properties
-
Fredrikson G, Stralfors P, Nilsson NO, Belfrage P: Hormone-sensitive lipase of rat adipose tissue: purification and some properties. J Biol Chem 356:6311-6320, 1981
-
(1981)
J Biol Chem
, vol.356
, pp. 6311-6320
-
-
Fredrikson, G.1
Stralfors, P.2
Nilsson, N.O.3
Belfrage, P.4
-
43
-
-
0032560615
-
Mutational analysis of structural features of rat hormone-sensitive lipase
-
Shen W, Patel S, Natu V, Kraemer F: Mutational analysis of structural features of rat hormone-sensitive lipase. Biochemistry 37:8973-8979, 1998
-
(1998)
Biochemistry
, vol.37
, pp. 8973-8979
-
-
Shen, W.1
Patel, S.2
Natu, V.3
Kraemer, F.4
|