Effects of tumor necrosis factor-α on insulin action in cultured human muscle cells

Diabetes

Volumn 50, Issue 5, 2001, Pages 1102-1109

  Halse, Reza ^a   Pearson, Samantha L ^a   McCormack, James G ^b   Yeaman, Stephen J ^a   Taylor, Roy ^a  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

^b NOVO NORDISK A S   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLINERGIC RECEPTOR; CREATINE KINASE; CYTOKINE; GLUCOSE; GLYCOGEN SYNTHASE KINASE 3; INSULIN; ISOPROTEIN; MYOGENIN; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CELL CULTURE; CELL DIFFERENTIATION; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; ENZYME INHIBITION; GLUCOSE METABOLISM; GLYCOGEN SYNTHESIS; HORMONE ACTION; HUMAN; HUMAN CELL; IN VITRO STUDY; INSULIN RESISTANCE; INSULIN SENSITIVITY; MUSCLE CELL; MYOBLAST; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

EID: 0035034309     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diabetes.50.5.1102     Document Type: Article

References (30)

1. The biology of cachectin/TNF alpha primary mediator of the host response
2. The metabolic effects of tumor necrosis factor and other cytokines
3. Adipose expression of tumor necrosis factor alpha: Direct role in obesity-linked insulin resistance
4. Increased adipose expression of tumor necrosis factor alpha in human obesity and insulin resistance
5. The expression of tumor necrosis factor in adipose tissue: Regulation by obesity, weight loss and relationship to lipoprotein lipase
6. The expression of TNF alpha by human muscle: Relationship to insulin resistance
7. Tumor necrosis factor alpha induced phosphorylation of insulin receptor substrate-1: Possible mechanism for suppression of insulin-stimulated tyrosine phosphorylation of IRS-1
8. IRS-1 mediated inhibition of insulin receptor tyrosine kinase activity in TNF alpha and obesity-induced insulin resistance
9. Tumor necrosis factor alpha inhibits insulin signaling through stimulation of the p55 receptor and activation of sphingomyelinase
10. Identification of serines-967/968 in the juxtamembrane region of the insulin receptor as insulin-stimulated phosphorylation sites
11. Studies into the identity of the sites of insulin-stimulated insulin receptor serine phosphorylation: Characterization of synthetic peptide substrates for the insulin-stimulated insulin receptor serine kinase
12. Mitogen-activated protein kinase activation is not necessary for, but antagonizes, 3T3-L1 adipocytic differentiation
13. Wortmannin and demethoxyviridin inhibit insulin stimulated phospholipase A2 activity in Swiss 3T3 cells
14. Peptide substrates suitable for assaying glycogen synthase kinase-3 in crude cell extracts
15. A quantitative technique for growing human adult skeletal muscle in culture starting from mononucleated cells
16. Isolation and characterization of human muscle cells
17. Insulin action in cultured human myoblasts: Contribution of different signalling pathways to regulation of glycogen synthesis
18. A rapid filter paper assay for UDP glucose-glycogen glucosyltransferase, including an improved biosynthesis of UDP-14C-glucose
19. Glycogen synthase: A new activity ratio assay expressing a high sensitivity to the phosphorylation state
20. Radioactive method for the assay of glycogen phosphorylases
21. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
22. Elevated serum tumour necrosis factor alpha levels can contribute to the insulin resistance in type 2 (non-insulin dependent) diabetes and obesity
23. Veterans Affairs Cooperative Study on glycemic control and complications in type II diabetes (VA CSDM): Results of the feasibility trial: Veterans affairs cooperative study in type II diabetes
24. Tumor necrosis factor alpha promotes phosphorylation and binding of IRS-1 to phosphatidylinositol 3-kinase in 3T3-L1 adipocytes
25. Effect of tumor necrosis factor alpha on insulin action in cultured rat skeletal muscle cells
26. Effects of tumor necrosis factor-alpha on glucose metabolism in cultured human muscle cells from nondiabetic and type 2 diabetic subjects
27. Acute and chronic exposure to tumor necrosis factor alpha fails to affect insulin stimulated glucose metabolism of isolated rat soleus muscle
28. NF-kappa-B induced loss of MyoD messenger RNA: Possible role in muscle decay and cachexia
29. Tumor necrosis factor alpha induced apoptosis is associated with suppression of insulin-like growth factor protein-5 secretion in differentiating murine skeletal myoblasts
30. Evidence of an increased number of type IIb muscle fibers in insulin-resistant first-degree relatives of patients with NIDDM